EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

2-methyl imidazole
1H-imidazole, 2-methyl-

Supplier Sponsors

Name:2-methyl-1H-imidazole
CAS Number: 693-98-1Picture of molecule3D/inchi
Other(deleted CASRN):112288-03-6
ECHA EINECS - REACH Pre-Reg:211-765-7
FDA UNII: T0049Z45LZ
Nikkaji Web:J49.341D
Beilstein Number:0001368
MDL:MFCD00005190
XlogP3:0.20 (est)
Molecular Weight:82.10582000
Formula:C4 H6 N2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 144.00 °C. @ 760.00 mm Hg
Boiling Point: 267.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.015000 mmHg @ 25.00 °C. (est)
Flash Point: 293.00 °F. TCC ( 144.90 °C. ) (est)
logP (o/w): 0.240
Soluble in:
 water, 8.085e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BASF
2-Methylimidazole
BOC Sciences
For experimental / research use only.
2-Methylimidazole
EMD Millipore
For experimental / research use only.
2-Methylimidazole
Glentham Life Sciences
2-Methylimidazole
Sigma-Aldrich: Aldrich
For experimental / research use only.
2-Methylimidazole 99%
TCI AMERICA
For experimental / research use only.
2-Methylimidazole >97.0%(GC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 480 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 14, Pg. 301, 1969.

oral-mouse LD50 1400 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 14, Pg. 301, 1969.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for 2-methyl imidazole usage levels up to:
 not for fragrance use.
 
Recommendation for 2-methyl imidazole flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):693-98-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :12749
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
2-methyl-1H-imidazole
Chemidplus:0000693981
RTECS:NI7175000 for cas# 693-98-1
 
References:
 2-methyl-1H-imidazole
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:693-98-1
Pubchem (cid):12749
Pubchem (sid):134976433
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
KEGG (GenomeNet):C19261
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2933.29.9000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 imidazole, 2-methyl-
1H-imidazole, 2-methyl-
2-methyimidazole
2-methyl-1H-imidazole
2-methylimdazole
2-methylimidazole
 

Articles:

PubMed:Second generation silver(I)-mediated imidazole base pairs.
PubMed:Separation and determination of 4-methylimidazole, 2-methylimidazole and 5-hydroxymethylfurfural in beverages by amino trap column coupled with pulsed amperometric detection.
PubMed:Combined Experimental and Theoretical Study on the Reactivity of Compounds I and II in Horseradish Peroxidase Biomimetics.
PubMed:Introduction of an Ionic Liquid into the Micropores of a Metal-Organic Framework and Its Anomalous Phase Behavior.
PubMed:Highly Porous ZIF-8 Nanocrystals Prepared by a Surfactant Mediated Method in Aqueous Solution with Enhanced Adsorption Kinetics.
PubMed:Structural insight into activity enhancement and inhibition of H64A carbonic anhydrase II by imidazoles.
PubMed:Determination of caramel colorants' by-products in liquid foods by ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).
PubMed:Solvent extraction of lanthanides and yttrium from aqueous solution with methylimidazole in an ionic liquid.
PubMed:Fabrication of a high-stability cross-linked quaternized poly(epichlorolydrin)/PTFE composite membrane via a facile route.
PubMed:New cyano bridged heteropolynuclear Cu(II) and Cd(II)-tetracyanopalladate(II) polymeric complexes with 2-methylimidazole ligand.
PubMed:SAR genotoxicity and tumorigenicity predictions for 2-MI and 4-MI using multiple SAR software.
PubMed:Zeolitic imidazolate framework-8 for fast adsorption and removal of benzotriazoles from aqueous solution.
PubMed:Correlated ligand dynamics in oxyiron picket fence porphyrins: structural and Mössbauer investigations.
PubMed:Probing heme vibrational anisotropy: an imidazole orientation effect?
PubMed:A two-dimensional zeolitic imidazolate framework with a cushion-shaped cavity for CO2 adsorption.
PubMed:In situ and real-time monitoring of mechanochemical milling reactions using synchrotron X-ray diffraction.
PubMed:Comparison and evaluation of five types of imidazole-modified silica adsorbents for the removal of 2,4-dinitrophenol from water samples with the methyl group at different positions of imidazolium ring.
PubMed:Determination of 2-methylimidazole and 4-methylimidazole in caramel colors by capillary electrophoresis.
PubMed:ZIF-8 crystal coatings on a polyimide substrate and their catalytic behaviours for the Knoevenagel reaction.
PubMed:Axial ligand exchange of N-heterocyclic cobalt(III) Schiff base complexes: molecular structure and NMR solution dynamics.
PubMed:Synthesis of N3'-P5'-linked phosphoramidate DNA by nonenzymatic template-directed primer extension.
PubMed:Studies on the activity of two Trans-planaramine platinum(II) complexes coded as DH4 and DH5 in human ovarian tumour models.
PubMed:Determination of 2-methylimidazole, 4-methylimidazole and 2-acetyl-4-(1,2,3,4-tetrahydroxybutyl)imidazole in caramel colours and cola using LC/MS/MS.
PubMed:Carcinogenicity and regulation of caramel colorings.
PubMed:Iridium nanoparticles stabilized by metal organic frameworks (IrNPs@ZIF-8): synthesis, structural properties and catalytic performance.
PubMed:CAF@ZIF-8: one-step encapsulation of caffeine in MOF.
PubMed:Chemical rescue of the distal histidine mutants of tryptophan 2,3-dioxygenase.
PubMed:Dichloridotris(2-methyl-1H-imidazole-κN(3))cadmium.
PubMed:Adsorption of Cd(II) and Pb(II) onto a one step-synthesized polyampholyte: kinetics and equilibrium studies.
PubMed:Aqueous room temperature synthesis of cobalt and zinc sodalite zeolitic imidizolate frameworks.
PubMed:Nuclear resonance vibrational spectra of five-coordinate imidazole-ligated iron(II) porphyrinates.
PubMed:Simultaneous quantitation of 2-acetyl-4-tetrahydroxybutylimidazole, 2- and 4-methylimidazoles, and 5-hydroxymethylfurfural in beverages by ultrahigh-performance liquid chromatography-tandem mass spectrometry.
PubMed:Bis-(2-methyl-1H-imidazole-κN)bis[2-(naphthalen-2-yl)acetato-κO]copper(II).
PubMed:Tetra-aqua-bis-(2-methyl-1H-imidazole-κN)cobalt(II) naphthalene-1,5-disulfonate.
PubMed:H/D isotopic recognition in hydrogen bonded systems: H/D isotopic self-organization effects in the IR spectra of the hydrogen bond in 2-methylimidazole crystals.
PubMed:1D and 2D assembly structures by imidazole···chloride hydrogen bonds of iron(II) complexes [Fe(II)(HL(n-Pr))3]Cl·Y (HL(n-Pr) = 2-methylimidazol-4-yl-methylideneamino-n-propyl; Y = AsF6, BF4) and their spin states.
PubMed:Water increases rates of epoxidation by Mn(III)porphyrins/imidazole/IO4(-) in CH2Cl2. Analogy with peroxidase and chlorite dismutase.
PubMed:Poly[(μ(3)-benzene-1,3,5-tricarboxyl-ato-κO:O:O)(μ(2)-2-methyl-imidazolato-κN:N')tris-(2-methyl-imidazole-κN)dizinc(II)].
PubMed:Fast nucleation and growth of ZIF-8 nanocrystals monitored by time-resolved in situ small-angle and wide-angle X-ray scattering.
PubMed:Investigation of porous Ni-based metal-organic frameworks containing paddle-wheel type inorganic building units via high-throughput methods.
PubMed:Unexpected property of ectoine synthase and its application for synthesis of the engineered compatible solute ADPC.
PubMed:N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase.
PubMed:Fluorescent-based solid sensor for HSO4(-) in water.
PubMed:Iron porphyrins with different imidazole ligands. A theoretical comparative study.
PubMed:Synthesis and properties of nano zeolitic imidazolate frameworks.
PubMed:Searching for multi-target antipsychotics: Discovery of orally active heterocyclic N-phenylpiperazine ligands of D2-like and 5-HT1A receptors.
PubMed:Oxygenation of cobalt porphyrinates: coordination or oxidation?
PubMed:Pressure-induced amorphization and porosity modification in a metal-organic framework.
PubMed:9-Triptycenecarboxylate-Bridged Diiron(II) Complexes: Capture of the Paddlewheel Geometric Isomer.
PubMed:Noncovalent synthesis of hierarchical zinc phosphates from a single Zn(4)O(12)P(4) double-four-ring building block: dimensionality control through the choice of auxiliary ligands.
PubMed:Effects of 4-methylimidazole on cerebral glutamate decarboxylase activity and specific GABA receptor binding in mice.
PubMed:New 2-methylimidazole-dicarboxylic acid molecular crystals: crystal structure and proton conductivity.
PubMed:3-Oxoandrosta-4,6-dien-17beta-yl 2-methyl-1H-imidazole-1-carboxylate and 3-oxo-5alpha-androst-17beta-yl 2-methyl-1H-imidazole-1-carboxylate: C-H...pi and pi-pi intermolecular interactions.
PubMed:Comparative analysis of mutant tyrosine kinase chemical rescue.
PubMed:Effect of imidazole and phenolate axial ligands on the electronic structure and reactivity of oxoiron(IV) porphyrin pi-cation radical complexes: drastic increase in oxo-transfer and hydrogen abstraction reactivities.
PubMed:Bis[2-(3,4-disulfanylphen-yl)acetato]bis-(2-methyl-1H-imidazole-κN)zinc(II).
PubMed:Synthesis and characterisation of mixed ligand Pt(II) and Pt(IV) oxadiazoline complexes.
PubMed:Hydrogen bonding influence of 1,10-phenanthroline on five-coordinate high-spin imidazole-ligated iron(II) porphyrinates.
PubMed:Synthesis of novel C17 steroidal carbamates. Studies on CYP17 action, androgen receptor binding and function, and prostate cancer cell growth.
PubMed:Lycopene production using Blakeslea trispora in the presence of 2-methyl imidazole: yield, selectivity, and safety aspects.
PubMed:Density functional theory calculations of the lowest energy quintet and triplet states of model hemes: role of functional, basis set, and zero-point energy corrections.
PubMed:Hydrogen bonding effects on the electronic configuration of five-coordinate high-spin iron(II) porphyrinates.
PubMed:Induction of thyroid and liver tumors by chronic exposure to 2-methylimidazole in F344/N rats and B6C3F1 mice.
PubMed:Temperature-dependent heme kinetics with nonexponential binding and barrier relaxation in the absence of protein conformational substates.
PubMed:Low frequency spectral density of ferrous heme: perturbations induced by axial ligation and protein insertion.
PubMed:Copper-catalyzed N-arylation of imidazoles and benzimidazoles.
PubMed:Absorption, metabolism, and excretion of [14C]imidafenacin, a new compound for treatment of overactive bladder, after oral administration to healthy male subjects.
PubMed:Manganese(II) tri-tert-butoxysilanethiolate complexes with imidazole-based coligands: a neutral complex with four independent ligands and MNOS2 core (M=Mn) related to the liver alcohol dehydrogenase catalytic center (M=Zn).
PubMed:Low-spin bis(2-methylimidazole)(octaethylporphyrinato)iron(III) chloride (perp-[Fe(OEP)(2-MeHIm)(2)]Cl): a consequence of hydrogen bonding?
PubMed:Systematic regulation of the enzymatic activity of phenylacetaldoxime dehydratase by exogenous ligands.
PubMed:Letter: Influence of experimental conditions on electrospray ionization mass spectrometry of ferrocenylalkylazoles.
PubMed:Pyrazolyl-functionalized 2-methylimidazolium-based ionic liquids and their palladium(II) complexes as recyclable catalysts.
PubMed:Reaction of azole heterocycles with tris(dimethylamino)borane, a new method for the construction of tripodal borate-centred ligands.
PubMed:Human serum albumin hybrid incorporating tailed porphyrinatoiron(II) in the alpha,alpha,alpha,beta-conformer as an O2-binding site.
PubMed:Spectroscopic characterization of hydroxide and aqua complexes of Fe(II)-protoheme, structural models for the axial coordination of the atypical heme of membrane cytochrome b6f complexes.
PubMed:Monocyclic carotenoid biosynthetic pathway in the yeast Phaffia rhodozyma (Xanthophyllomyces dendrorhous).
PubMed:Heme carbonyls: environmental effects on nu(C-O) and Fe-C/C-O bond length correlations.
PubMed:NMR and EPR studies of low-spin Fe(III) complexes of meso-tetra-(2,6-disubstituted phenyl)porphyrinates complexed to imidazoles and pyridines of widely differing basicities.
PubMed:Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice.
PubMed:NMR and theoretical study on the coordination and solution structures of the interaction between diperoxovanadate complexes and histidine-like ligands.
PubMed:Ligand orientation control in low-spin six-coordinate (porphinato)iron(II) species.
PubMed:E.S.R., magnetic, electronic and superoxide dismutase studies of imidazolate-bridged Cu(II)-Cu(II) complexes with ethylenediamine as capping ligand.
PubMed:Thermodynamic profiles for CO photodissociation from heme model compounds: effect of proximal ligands.
PubMed:Efficacy of colestimide coadministered with atorvastatin in japanese patients with heterozygous familial hypercholesterolemia (FH).
PubMed:Epididymal sperm granuloma induced by chronic administration of 2-methylimidazole in B6C3F1 mice.
PubMed:[Synthesis and spectral properties of tailed sercine tetraphenylporphyrin cobalt complex].
PubMed:Toxicology and carcinogensis studies of 2-methylimidazole (Cas No. 693-98-1) in B6C3F1 mice (feed studies).
PubMed:From model compounds to protein binding: syntheses, characterizations and fluorescence studies of [RuII(bipy)(terpy)L]2+ complexes (bipy = 2,2'-bipyridine; terpy = 2,2':6',2''-terpyridine; L = imidazole, pyrazole and derivatives, cytochrome c).
PubMed:Effect of bis(acetato)tetrakis(imidazole) copper(II) in delaying the onset and reducing the mortality rate of strychnine- and thiosemicarbazide- induced convulsions.
PubMed:Reactions of antimicrobial species to imidazole-microwave plasma reacted poly(dimethylsiloxane) surfaces.
PubMed:Study on reactions of 2-(dinitromethylene)-4,5-imidazolidinedione.
PubMed:Proximal and distal influences on ligand binding kinetics in microperoxidase and heme model compounds.
PubMed:NTP technical report on the toxicity studies of 2- and 4-Methylimidazole (CAS No. 693-98-1 and 822-36-6) administered in feed to F344/N rats and B6C3F1 mice.
PubMed:Synthesis of N-alkylated derivatives of imidazole as antibacterial agents.
PubMed:A new family of spin crossover complexes with a tripod ligand containing three imidazoles: synthesis, characterization, and magnetic properties of [FeIIH3LMe](NO3)2.1.5H2O, [FeIIILMe].3.5H2O, [FeIIH3LMe][FeIILMe]NO3, and [FeIIH3LMe][FeIIILMe](NO3)2 (H3LMe) = Tris[2-(((2-methylimidazol-4-yl)methylidene)amino)ethyl]amine).
PubMed:Synthesis and in vitro pharmacology of novel heterocyclic muscarinic ligands.
PubMed:Models of the bis-histidine-coordinated ferricytochromes: Mössbauer and EPR spectroscopic studies of low-spin iron(III) tetrapyrroles of various electronic ground states and axial ligand orientations.
PubMed:Induced fit process in the selective distal binding of imidazoles in zinc(II) porphyrin receptors.
PubMed:Electrochemical and NMR spectroscopic studies of distal pocket mutants of nitrophorin 2: stability, structure, and dynamics of axial ligand complexes.
PubMed:Effects of a nonplanar porphyrin rings on the spin-spin interactions in low-spin ferric porphyrin radical cationst.
PubMed:Preparation of unsymmetrical sulfonylureas from N,N'-sulfuryldiimidazoles.
PubMed:Iron normal mode dynamics in a porphyrin-imidazole model for deoxyheme proteins.
PubMed:Paramagnetic resonance in imidazolate-bridged homobinuclear (copper-copper) and heterobinuclear (copper-zinc) complexes.
PubMed:Biomimetic oxidation of 2-methylimidazole derivative with a chemical model system for cytochrome P-450.
PubMed:Toxicokinetics of 2-methylimidazole in male and female F344 rats.
PubMed:Effect of heme structure on O(2)-binding properties of human serum albumin-heme hybrids: intramolecular histidine coordination provides a stable O(2)-adduct complex.
PubMed:Control of cytochrome C redox potential: axial ligation and protein environment effects.
PubMed:Structure of the deoxymyoglobin model [Fe(TPP)(2-MeHIm)] reveals unusual porphyrin core distortions.
PubMed:Spectroscopic studies on human serum albumin and methemalbumin: optical, steady-state, and picosecond time-resolved fluorescence studies, and kinetics of substrate oxidation by methemalbumin.
PubMed:Low-Spin Iron(III) Chiroporphyrins: (1)H NMR Studies of Cyanide and Substituted Imidazole Coordination.
PubMed:Copper(II) Complexes of N,N'-Bis((2-substituted-imidazol-4-yl)methylene)-3,3'-diaminodi- propylamine (2-Substituent = H, Me): Delta and Lambda Enantiomorphs of the Protonated Complex and Helical Structure of the Deprotonated Complex Formed by Hydrogen Bonds.
PubMed:Properties of a binaphthyl-bridged porphyrin-iron complex bearing hydroxy groups inside its cavity.
PubMed:Molecular structures and magnetic resonance spectroscopic investigations of highly distorted six-coordinate low-spin iron(III) porphyrinate complexes.
PubMed:Spectroscopic, kinetic, and mechanistic study of a new mode of coordination of indole derivatives to platinum(II) and palladium(II) ions in complexes.
PubMed:Inhibition of neuronal nitric oxide synthase by N-phenacyl imidazoles.
PubMed:Kinetic studies of imidazole and its methyl derivative binding to metmyoglobin: effects of substitute methyl on the binding affinity.
PubMed:Nonenzymatic oligomerization on templates containing phosphodiester-linked acyclic glycerol nucleic acid analogues.
PubMed:Comparison of imidazole- and 2-methyl imidazole-containing farnesyl-protein transferase inhibitors: interaction with and metabolism by rat hepatic cytochrome P450s.
PubMed:Relative reactivity of ribosyl 2'-OH vs. 3'-OH in concentrated aqueous solutions of phosphoimidazolide activated nucleotides.
PubMed:The binding of imidazole in an azurin-like blue-copper site.
PubMed:Retention mechanism of imidazoles in connective tissue. IV. Identification of a nucleophilic imidazolone metabolite in rats.
PubMed:Novel imidazole derivatives with subtype-selective antimuscarinic activity (1).
PubMed:Oligomerization of activated D- and L-guanosine mononucleotides on templates containing D- and L-deoxycytidylate residues.
PubMed:Retention mechanism of imidazoles in connective tissue. III. Aldehyde adduct formation of a 4(5H)(or5(4H))-imidazolone product in vitro.
PubMed:Imidazoles suppress rat testosterone secretion and testicular interstitial fluid formation In vivo.
PubMed:Disposition of 2-methylimidazole in rats.
PubMed:Mutational analysis of the role of the distal histidine and glutamine residues of prostaglandin-endoperoxide synthase-2 in peroxidase catalysis, hydroperoxide reduction, and cyclooxygenase activation.
PubMed:Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.
PubMed:Oxomolybdenum(V)/Iron(III) Porphyrinate Complexes: Effect of Axial Ligand Plane Orientation on Complex Stability, Reduction Potential, and NMR and EPR Spectra.
PubMed:Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: protein N-myristoyltransferase: a new approach to antifungal therapy.
PubMed:Retention mechanism of imidazoles in connective tissue. I. Binding to elastin.
PubMed:Hypoglycemic effect of copper(II) acetate imidazole complexes.
PubMed:Coordination of copperpolyamine complex with imidazoles potentiates it superoxide dismutase mimicking activity and abolishes its interaction with albumin.
PubMed:Rescue of the catalytic activity of an H42A mutant of horseradish peroxidase by exogenous imidazoles.
PubMed:Fixation of the 2-Methylimidazole Ligand and Anomalous Pyrrole Chemical Shifts in Bis(2-methylimidazole)(meso-tetraalkylporphyrinato)iron(III) Chloride Caused by the Nonplanar Porphyrin Ring.
PubMed:Structure of metal site in Cd-substituted His117Gly mutant of azurin with and without addition of imidazole derivatives.
PubMed:Marked effects of alcohols and imidazoles on the cumyl hydroperoxide reaction with the wild-type cytochrome P450 1A2.
PubMed:Large steric effect in the substitution reaction of amines with phosphoimidazolide-activated nucleosides.
PubMed:The effects of phenelzine and other monoamine oxidase inhibitor antidepressants on brain and liver I2 imidazoline-preferring receptors.
PubMed:Mononuclear and binuclear copper(II) complexes of the antiinflammatory drug ibuprofen: synthesis, characterization, and catecholase-mimetic activity.
PubMed:Inhibition of p-nitrophenol hydroxylase in rat liver microsomes by small aromatic and heterocyclic molecules.
PubMed:Small molecule binding to an artificially created cavity at the active site of cytochrome c peroxidase.
PubMed:Synthesis of porphinatoirons having an alkyl amphiphilic chain and their O2 binding properties in lipid bilayers.
PubMed:Nitroimidazoles, XIV: Synthesis of 4-nitroimidazoles with 1-substituents containing acid, ester or phenol functions, and radiosensitizing efficiency of some of these compounds.
PubMed:Synthesis and antineoplastic activity of some cyano-, carboxy-, carbomethoxy-, and carbamoylborane adducts of heterocyclic amines.
PubMed:Contribution of protein conformation to heme stereochemistry and reactivity. Low-temperature magnetic circular dichroism data.
PubMed:Uranyl-ion catalyzed oligonucleotide synthesis from adenosine-5'-phosphorazolide. The effect of azoles as nucleotide activating groups.
PubMed:[Contribution of protein conformation to stereochemistry and reactivity of the active center of heme proteins and enzymes. The existence of horseradish peroxidase conformations and their possible role in the catalysis mechanism].
PubMed:Heme-linked ionization and ligand binding produce identical changes of proximal heme stereochemistry in reduced horseradish peroxidase. Evidence for existence of two protein conformations.
PubMed:Bile acid binding and hypocholesterolemic activity of a new anion exchange resin from 2-methylimidazol and epichlorohydrin.
PubMed:Resonance Raman studies of dioxygen and carbon monoxide binding to imidazole-appended hemes.
PubMed:Formation of an amino reduction product of metronidazole in bacterial cultures: lack of bactericidal activity.
PubMed:Effects of imidazole and some imidazole-derivatives on lisuride-induced mounting and aggressiveness.
PubMed:Template-directed synthesis on short oligoribocytidylates.
PubMed:Inhibition of tolbutamide metabolism by substituted imidazole drugs in vivo: evidence for a structure-activity relationship.
PubMed:Spin-state equilibrium in the model complexes of azide hemoprotein.
PubMed:A simple and convenient synthesis of 3'-5'- or 2'-5'-linked oligoribonucleotide by polymerization of unprotected ribonucleoside using phosphorus tris-azole.
PubMed:The prebiotic synthesis and catalytic role of imidazoles and other condensing agents.
PubMed:Template-directed synthesis with 2-aminoadenosine.
PubMed:Role of sulfhydryl compounds in the bactericidal effect of metronidazole.
PubMed:Liposomal heme as oxygen carrier under semi-physiological conditions. Orientation study of heme embedded in a phospholipid bilayer by an electrooptical method.
PubMed:Chemotherapy of childhood rhabdomyosarcomas growing as xenografts in immune-deprived mice.
PubMed:Preliminary evaluation of mesoionic 6-substituted 1-methylimidazo[2,1-b][1,3]thiazine-5,7-diones as potential novel prodrugs of methimazole.
PubMed:Proximal strain and visible absorption changes in the model complexes of imidazole methemoglobin.
PubMed:Magnetic circular dichroism studies of cytochrome P-450cam. Characterization of axial ligands of ferric and ferrous low-spin complexes.
PubMed:Selective inhibition of thromboxane biosynthesis in human blood mononuclear cells and the effects of mitogen-stimulated lymphocyte proliferation.
PubMed:The coordination environment of mitochondrial cytochromes b.
PubMed:Binding of imidazoles to manganese (III) protoporphyrin in water.
PubMed:Copper (II) complex-catalyzed oxidation of NADH by hydrogen peroxide.
PubMed:The preoperative use of cimetidine in reducing acidity of gastric secretion.
PubMed:Proton nmr spectroscopy of high-spin ferrous cytochrome P-450 models.
PubMed:1H-NMR and rosonance Raman spectra of octaethylporphyrinatoiron(III) perchlorate and its mono imidazole adduct.
PubMed:High magnetic field Mössbauer studies of deoxymyoglobin, deoxyhemoglobin, and synthetic analogues.
PubMed:Chemical and enzymatic intermediates in the peroxidation of o-dianisidine by horseradish peroxidase. 2. Evidence for a substrate radical--enzyme complex and its reaction with nucleophiles.
PubMed:Absence of heme-localized strain in T state hemoglobin: insensitivity of heme-imidazole resonance Raman frequencies to quaternary structure.
PubMed:Reduction by dithionite ion of adducts of metmyoglobin with imidazole, pyridine, and derivatives.
PubMed:Oxygen binding to cobalt(II) proto-, deutero- and meso-porphyrin IX dimethyl ester complexes in organic solvents.
PubMed:Complexes between synthetic polymer ligands and ferri-delta and ferro-protoporphyrin IX.
PubMed:Spectroscopic properties of ferrous heme complexes of sterically hindered ligands.
PubMed:Modification by imidazoles of ocular inflammatory and pressure responses.
PubMed:Which of caffeine's chemical relatives are able to evoke contractures in mammalian heart?
PubMed:Antimetastatic effect of 4-carbethoxy-5-(3,3-dimethyl-1-triazeno)-2-methylimidazole.
PubMed:Binding of imidazole and 2-methylimidazole by hemes in organic solvents. Evidence for five-coordination.
PubMed:Evaluation of 4-carbethoxy-5(3,3-dimethyl-1-triazeno)-2-phenylimidazole (NSC-166721) and 4-carbethoxy-5-(3,3-dimethyl-1-triazeno)-2-methylimidazole (NSC-166722) as potential antitumor agents.
PubMed:DL-1-( -methylbenzyl)-2-methylimidazole-5-carboxylate esters. Synthesis and pharmacological properties.
 
Notes:
None found
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy