2(5H)-furanone
4-hydroxy-2-butenoic acid gamma-lactone

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  Beijing Lys Chemicals Co, LTD.

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  BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
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  10473 2(5H)-Furanone

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  497-23-4 2(5H)-Furanone 96%

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  Penta International Corporation

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  For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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  08-58350 4-HYDROXY-2-BUTENOIC ACID GAMMA-LACTONE

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  Soda Aromatic Co., Ltd.

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  Our international sales department is happy to design the most suitable flavor & fragrance for specific uses of processed food, cosmetics, and fragrance manufactures all over the world, specializing in Asia.Let us help you with your flavor & fragrance needs.
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  110204007 2-Buten-4-olide

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  TCI AMERICA

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  C1078 gamma-Crotonolactone >93.0%(GC)
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  Tianjin Danjun International Trade Co., LTD.

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  Tianjin danjun international trade co., LTD. is an organic chemicals trading company approved by the relevant state authorities to register. We have about 300 kinds of products (natural aroma chemicals, synthetic aroma chemicals and pharmaceutical intermediates). Most of the products are used in flavor and fragrance industry. We know the Chinese chemical market well and we have close relationship with many of the main manufacturers, and to provide our customers with quality goods together with comprehensive service.
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  5H-furan-2-one

Name: 5H-furan-2-one CAS Number: 497-23-4 3D/inchi ECHA EINECS - REACH Pre-Reg: 207-839-3 FDA UNII: 8KXK25H388 Nikkaji Web: J82.323F Beilstein Number: 0383585 MDL: MFCD00005376 XlogP3: -0.60 (est) Molecular Weight: 84.07428000 Formula: C4 H4 O2 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category: flavoring agents   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search JECFA Food Flavoring: 2000 4-hydroxy-2-butenoic acid gamma-lactone DG SANTE Food Flavourings: 10.066 furan-2(5H)-one FEMA Number: 4138 4-hydroxy-2-butenoic acid gamma-lactone FDA: No longer provide for the use of these seven synthetic flavoring substances FDA Mainterm (SATF): 497-23-4 ; 4-HYDROXY-2-BUTENOIC ACID GAMMA-LACTONE   Physical Properties: Appearance: colorless to pale brown yellow clear liquid (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Specific Gravity: 1.18200 to 1.18800 @ 25.00 °C. Pounds per Gallon - (est).: 9.835 to 9.885 Refractive Index: 1.46600 to 1.47200 @ 20.00 °C. Melting Point: 4.00 to 5.00 °C. @ 760.00 mm Hg Boiling Point: 86.00 to 87.00 °C. @ 12.00 mm Hg Boiling Point: 214.00 °C. @ 760.00 mm Hg Vapor Pressure: 0.273000 mmHg @ 25.00 °C. (est) Flash Point: 214.00 °F. TCC ( 101.11 °C. ) logP (o/w): -0.600 Shelf Life: 12.00 month(s) or longer if stored properly. Storage: refrigerate in tightly sealed containers. Soluble in:   alcohol   water, 4.178e+005 mg/L @ 25 °C (est)   Organoleptic Properties: Odor Type: buttery buttery Odor Description:buttery Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: Beijing Lys Chemicals 2(5H)-Furanone BOC Sciences For experimental / research use only. 2(5H)-Furanone 96% Parchem 2(5H)-furanone Penta International 4-HYDROXY-2-BUTENOIC ACID GAMMA-LACTONE Santa Cruz Biotechnology For experimental / research use only. 2(5H)-furanone Sigma-Aldrich: Aldrich For experimental / research use only. 2(5H)-Furanone 98% sds Soda Aromatic 2-Buten-4-olide TCI AMERICA For experimental / research use only. gamma-Crotonolactone >93.0%(GC) sds Tengzhou Xiang Yuan Aroma Chemicals Gamma-Crotolactone Tianjin Danjun International 5H-furan-2-one WholeChem 5H-furan-2-one   Safety Information: Preferred SDS: View European information : Most important hazard(s): Xi - Irritant R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: Not determined Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: flavoring agents Recommendation for 2(5H)-furanone usage levels up to:   not for fragrance use.   Maximised Survey-derived Daily Intakes (MSDI-EU): 0.01 (μg/capita/day) Structure Class: III Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library publication number: 22 Click here to view publication 22   average usual ppm average maximum ppm baked goods: - - beverages(nonalcoholic): - - beverages(alcoholic): 3.50000 5.00000 breakfast cereal: - - cheese: - - chewing gum: - - condiments / relishes: - - confectionery froastings: - - egg products: - - fats / oils: - - fish products: - - frozen dairy: - - fruit ices: - - gelatins / puddings: - - granulated sugar: - - gravies: - - hard candy: - - imitation dairy: - - instant coffee / tea: - - jams / jellies: - - meat products: 3.80000 5.00000 milk products: - - nut products: - - other grains: - - poultry: - - processed fruits: - - processed vegetables: - - reconstituted vegetables: - - seasonings / flavors: - - snack foods: - - soft candy: - - soups: - - sugar substitutes: - - sweet sauces: - -   Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.   average usage mg/kg maximum usage mg/kg Dairy products, excluding products of category 02.0 (01.0): 3.87000 14.99000 Fats and oils, and fat emulsions (type water-in-oil) (02.0): 1.00000 2.38000 Edible ices, including sherbet and sorbet (03.0): 1.00000 150.50000 Processed fruit (04.1): - - Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): 0.55000 0.90000 Confectionery (05.0): 7.64000 21.05000 Chewing gum (05.3): - - Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 5.33000 14.99000 Bakery wares (07.0): 4.08000 15.06000 Meat and meat products, including poultry and game (08.0): 0.00800 2.13000 Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): - - Eggs and egg products (10.0): - - Sweeteners, including honey (11.0): - - Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 1.20000 5.00000 Foodstuffs intended for particular nutritional uses (13.0): - - Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 1.90000 5.41000 Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 0.08100 3.10000 Ready-to-eat savouries (15.0): 0.05000 0.27000 Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): - -   Safety References: European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... European Food Safety Authority (EFSA) reference(s): List of apha, beta-Unsaturated Aldehydes and Ketones representative of FGE.19 substances for Genotoxicity Testing [1] - Statement of the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) View page or View pdf Flavouring Group Evaluation 217: alpha,beta-Unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones[1] View page or View pdf Scientific Opinion on Flavouring Group Evaluation 217, Revision 1 (FGE.217Rev1). Consideration of genotoxic potential for a,ß-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones View page or View pdf Scientific Opinion on Flavouring Group Evaluation 217 Revision 2 (FGE.217Rev2), consideration of genotoxic potential for a,ß-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: lactones View page or View pdf EPI System: View Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA GENetic TOXicology:Search EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :10341 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 5H-furan-2-one Chemidplus:0000497234 RTECS:LU3453000 for cas# 497-23-4   References:   5H-furan-2-one NIST Chemistry WebBook: Search Inchi Pubchem (cid): 10341 Pubchem (sid): 134977583   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View CHEBI: View CHEMBL: View KEGG (GenomeNet): C17601 HMDB (The Human Metabolome Database): HMDB32330 FooDB: FDB009600 Export Tariff Code: 2932.29.5050 VCF-Online: VCF Volatile Compounds in Food ChemSpider: View Wikipedia: View EFSA Update of results on the monitoring of furan levels in food: Read Report EFSA Previous report: Results on the monitoring of furan levels in food: Read Report EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report FAO: 4-Hydroxy-2-butenoic acid gamma-lactone   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   beer Search Picture   bread white bread Search Picture   coffee Search PMC Picture   filbert roasted filbert Search Picture   fish Search Picture   hazelnut Search Picture   honey Search Picture   licorice root Search Picture   onions heated in butter Search Picture   peanut roasted peanut Search Picture   pomegranate fruit juice Search Trop Picture   saffron Search Trop Picture   tea rooibos tea Search Trop Picture   wood smoke Search Picture   Synonyms: 2- buten-1,4-olide 2- buten-4-olide 2- butenoic acid gamma-lactone 2- butenolide delta,alpha,beta- butenolide gamma- crotolactone alpha,beta- crotonolactone gamma- crotonolactone iso crotonolactone 2-oxo-2,5- dihydrofuran 5H- furan-2-one   furan-2(5H)-one   furan-2(5H)-one; 2-Buten-1,4-olide 2[5H]- furanone 5- hydrofuran-2-one 4- hydroxy-2-butenoic acid gamma-lactone 4- hydroxy-2-butenoic acid lactone 4- hydroxycrotonic acid gamma-lactone gamma- hydroxycrotonic acid lactone   Articles:   None found yet. 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Notes: inhibits experimental allergic encephalomyelitis in rats. Used as a food additive [EAFUS]