1,2-dichloroethane
1,2-ethylidene dichloride

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Name: 1,2-dichloroethane CAS Number: 107-06-2 3D/inchi ECHA EINECS - REACH Pre-Reg: 203-458-1 FDA UNII: 55163IJI47 Nikkaji Web: J4.049E Beilstein Number: 605264 MDL: MFCD00000963 XlogP3: 1.50 (est) Molecular Weight: 98.95788000 Formula: C2 H4 Cl2 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:extraction solvents   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search FDA Mainterm (SATF): 107-06-2 ; ETHYLENE DICHLORIDE FDA Regulation: FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart D--Special Dietary and Nutritional Additives Sec. 172.385 Whole fish protein concentrate. FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart F--Flavoring Agents and Related Substances Sec. 172.560 Modified hop extract. FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION H--Other Specific Usage Additives Sec. 172.710 Adjuvants for pesticide use dilutions. FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION Subpart C--Solvents, Lubricants, Release Agents and Related Substances Sec. 173.230 Ethylene dichloride. FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION Subpart D--Specific Usage Additives Sec. 173.315 Chemicals used in washing or to assist in the peeling of fruits and vegetables. FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart B--Substances for Use Only as Components of Adhesives Sec. 175.105 Adhesives. FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS Subpart B--Substances for Use Only as Components of Paper and Paperboard Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Surfaces Sec. 177.1580 Polycarbonate resins. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Surfaces Sec. 177.1585 Polyestercarbonate resins. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use Sec. 177.2550 Reverse osmosis membranes. FDA PART 573 -- FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Subpart B--Food Additive Listing Sec. 573.440 Ethylene dichloride. FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Subpart A--Foods Sec. 73.30 Annatto extract. FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Subpart A--Foods Sec. 73.345 Paprika oleoresin. FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Subpart A--Foods Sec. 73.615 Turmeric oleoresin.   Physical Properties: Food Chemicals Codex Listed: No Specific Gravity: 1.25600 @ 25.00 °C. Boiling Point: 83.00 to 84.00 °C. @ 760.00 mm Hg Vapor Pressure: 78.900000 mmHg @ 25.00 °C. Flash Point: 60.00 °F. TCC ( 15.56 °C. ) logP (o/w): 1.480 Soluble in:   water, 8600 mg/L @ 25 °C (exp)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: not used anymore   Suppliers: Covalent Chemical Ethylene Dichloride Shandong Luyue Chemical Dichloroethane(EDC) Sigma-Aldrich For experimental / research use only. 1,2-Dichloroethane anhydrous, 99.8% Wedor Corporation ETHYLENE DICHLORIDE   Safety Information:   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-rat LD50 670 mg/kg Farm Chemicals Handbook. Vol. -, Pg. C130, 1991. oral-dog LD50 5700 mg/kg BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: ATAXIA SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 91, 1970. intravenous-dog LDLo 175 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. intraperitoneal-guinea pig LDLo 600 mg/kg American Industrial Hygiene Association Journal. Vol. 35, Pg. 21, 1974. oral-human LDLo 286 mg/kg LIVER: FATTY LIVER DEGERATION GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH Casopis Lekaru Ceskych. Journal of Czech Physicians. Vol. 86, Pg. 203, 1947. oral-human TDLo 428 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITING LUNGS, THORAX, OR RESPIRATION: COUGH BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Sovetskaia Meditsina. Vol. 22(10), Pg. 132, 1958. oral-man LDLo 714 mg/kg LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) CARDIAC: CHANGE IN RATE Klinische Wochenscrift. Vol. 48, Pg. 822, 1970. oral-man TDLo 892 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITING LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED" GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" Wiadomosci Lekarskie. Medical News. Vol. 28, Pg. 983, 1975. intraperitoneal-mouse LD50 470 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 902, 1961. oral-mouse LD50 413 mg/kg LIVER: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES EHP, Environmental Health Perspectives. Vol. 43, Pg. 41, 1982. oral-rabbit LD50 860 mg/kg Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 264, 1973. intraperitoneal-rat LD50 807 mg/kg Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 26(4), Pg. 26, 1982. intratracheal-rat LDLo 120 mg/kg National Technical Information Service. Vol. OTS0520615 Dermal Toxicity: skin-rabbit LD50 2800 mg/kg BEHAVIORAL: ATAXIA SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: GENERAL ANESTHETIC FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 91, 1970. subcutaneous-mouse LDLo 380 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945. subcutaneous-rabbit LDLo 1200 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. subcutaneous-rat LD50 1000 mg/kg BEHAVIORAL: GENERAL ANESTHETIC SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: ATAXIA FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 91, 1970. Inhalation Toxicity: inhalation-rat LC50 1000 ppm/7H BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: CYANOSIS AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 482, 1951. inhalation-cat LC > 3000 ppm/7H Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945. inhalation-guinea pig LCLo 1500 ppm/7H BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945. inhalation-mammal (species unspecified) LC > 3000 ppm/7H Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945. inhalation-man TCLo 4000 ppm/1H BEHAVIORAL: COMA PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) GASTROINTESTINAL: NAUSEA OR VOMITING Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 500, 1966. inhalation-mouse LCLo 5000 mg/m3/2H Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 141, Pg. 19, 1929. inhalation-rabbit LCLo 3000 ppm/7H LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945.   Safety in Use Information: Category: extraction solvents Recommendation for 1,2-dichloroethane usage levels up to:   not for fragrance use.   Recommendation for 1,2-dichloroethane flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View EPA-Iris:IRIS NIOSH International Chemical Safety Cards:search NIOSH Pocket Guide:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search Carcinogenic Potency Database:Search EPA GENetic TOXicology:Search EPA Substance Registry Services (TSCA):107-06-2 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :11 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 1,2-dichloroethane Chemidplus:0000107062 EPA/NOAA CAMEO:hazardous materials RTECS:107-06-2   References:   1,2-dichloroethane NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 107-06-2 Pubchem (cid): 11 Pubchem (sid): 134972247   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View FDA Indirect Additives used in Food Contact Substances: View CHEBI: View CHEMBL: View Metabolomics Database: Search UM BBD: Search KEGG (GenomeNet): C06752 HMDB (The Human Metabolome Database): HMDB29571 FooDB: FDB000726 Export Tariff Code: 2903.15.0000 FDA Listing of Food Additive Status: View Wikipedia: View Formulations/Preparations: •usepaopp pesticide code 042003; trade names: ent-1656; borer sol; brocide; destruxol borer-sol; dichloremulsion; dowfume; dutch liquid; dutch oil; freon 150. •granosan: disinfectant composed of 30% carbon tetrachloride and 70% ethylene dichloride. •grades: technical, spectrophotometric. •ethylene dichloride - carbon tetrachloride (dowfume 75). principal ingredient: 1,2-dichloroethane, commercial formulation, 70% active ingredient; & tetrachloromethane, commercial formulation, 30% active ingredient .   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms: 1,2- bichloroethane alpha,beta- dichloroethane   ethylene dichloride 1,2- ethylene dichloride 1,2- ethylidene dichloride   Articles:   None found yet. 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Notes: Solvent used in food processing The chemical compound 1,2-dichloroethane, commonly known by its old name of ethylene dichloride (EDC), is a chlorinated hydrocarbon, mainly used to produce vinyl chloride monomer (VCM, chloroethene), the major precursor for PVC production. It is a colourless liquid with a chloroform-like odour. 1,2-Dichloroethane is also used generally as an intermediate for other organic chemical compounds, and as a solvent.

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