fd&c blue no. 2 (c.i. 73015 (Na))
indigotine

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  860-22-0 Indigo Carmine PRACTICAL

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  I0214 Indigo Carmine >95.0%(E)
  SDS

CAS Number: 860-22-0 3D/inchi ECHA EINECS - REACH Pre-Reg: 212-728-8 FDA UNII: D3741U8K7L Beilstein Number: 4103904 MDL: MFCD00005723 Molecular Weight: 468.37283856 Formula: C16 H10 N2 Na2 O8 S2 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:coloring agents   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   FDA/DG SANTE Petitions, Reviews, Notices: EU SANCO Indigotine, Indigo carmine View - review JECFA Food Additive: Indigotine GSFA Codex: Indigotine (Indigo carmine) (132) DG SANTE Food Additives: indigotine FDA Mainterm (SATF): 860-22-0 ; FD&C BLUE NO. 2 FDA Regulation: FDA PART 74 -- LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Subpart A--Foods Sec. 74.102 FD&C Blue No. 2. FDA PART 74 -- LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Subpart B--Drugs Sec. 74.1102 FD&C Blue No. 2. FDA PART 82 -- LISTING OF CERTIFIED PROVISIONALLY LISTED COLORS AND SPECIFICATIONS Subpart B--Foods, Drugs, and Cosmetics Sec. 82.102 FD&C Blue No. 2.   Physical Properties: Appearance: blue powder (est) Assay: 85.00 to 100.00 Food Chemicals Codex Listed: No Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est) logP (o/w): 1.627 (est) Soluble in:   water, 1e+006 mg/L @ 25 °C (est)   water, 1.00E+04 mg/L @ 25 °C (exp)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data2 CosIng: cosmetic data Cosmetic Uses: cosmetic colorants   Suppliers: BOC Sciences For experimental / research use only. Indigo Carmine PRACTICAL EMD Millipore For experimental / research use only. Indigo carmine (C.I. 73015) sds Flavorchem FD&C Blue No. 2 Glentham Life Sciences Indigo Carmine (C.I. 73015) Kishi Kasei Blue No.2 Pangaea Sciences Indigo Rung International FD&C Blue No.2 Rung International Lake Indigo Carmine Santa Cruz Biotechnology For experimental / research use only. Indigo carmine Sigma-Aldrich For experimental / research use only. Indigo carmine analytical standard TCI AMERICA For experimental / research use only. Indigo Carmine >95.0%(E) sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-rat LD50 2000 mg/kg Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979. oral-mouse LD50 2500 mg/kg Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979. intravenous-rat LD50 93 mg/kg Drugs in Japan Vol. 6, Pg. 83, 1982. Dermal Toxicity: subcutaneous-mouse LD50 405 mg/kg Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979. Inhalation Toxicity: Not determined   Safety in Use Information: Category: coloring agents Recommendation for fd&c blue no. 2 (c.i. 73015 (Na)) usage levels up to:   not for fragrance use.   Recommendation for fd&c blue no. 2 (c.i. 73015 (Na)) flavor usage levels up to:   not for flavor use.   Safety References: European Food Safety Authority (EFSA) reference(s): Scientific Opinion on the re-evaluation of Indigo Carmine (E 132) as a food additive View page or View pdf Scientific Opinion on the safety and efficacy of indigo carmine (E 132) for cats and dogs and ornamental fish View page or View pdf EPI System: View ClinicalTrials.gov:search Daily Med:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search Carcinogenic Potency Database:Search EPA GENetic TOXicology:Search EPA Substance Registry Services (TSCA):860-22-0 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :5282429 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 disodium;(2E)-3-oxo-2-(3-oxo-5-sulfo-1H-indol-2-ylidene)-1H-indole-5-sulfonic acid Chemidplus:0000860220 EPA/NOAA CAMEO:hazardous materials RTECS:DU3000000 for cas# 860-22-0   References:   disodium;(2E)-3-oxo-2-(3-oxo-5-sulfo-1H-indol-2-ylidene)-1H-indole-5-sulfonic acid NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 860-22-0 Pubchem (cid): 5282429 Pubchem (sid): 134980234   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View HMDB (The Human Metabolome Database): Search FooDB: FDB011141 Export Tariff Code: 3204.12.0000 FDA Color Additive Status List View ChemSpider: View Formulations/Preparations: marketed as a paste with water; the dye contents varying according to specification or requirements of the user. it almost always contains sodium chloride or sulfate used for "salting" it out.   Potential Blenders and core components note None Found   Potential Uses:   cosmetic colorants   hair dyeing agents   Occurrence (nature, food, other):note   not found in nature   Synonyms:   acid blue 74   acid blue 74 (c.i. 73015 (Na)) (d(sup 2,2')- biindoline)-5,5'-disulfonic acid, 3,3'-dioxo-, disodium salt (d2,2'- biindoline)-5,5'-disulfonic acid, 3,3'-dioxo-, disodium salt   c.i. 73015 (Na)   c.i. 75781   C.I. food blue 1, disodium salt   C.I. natural blue 2   ci 73015 (Na)   ci 75781 2-(1,3- dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-1H-indole-5-sulfonic acid, disodium salt   disodium 3,3'-dioxo-(d(sup 2,2')-biindoline)-5,5'-disulfonate   disodium 3,3'-dioxo-(d2,2'-biindoline)-5,5'-disulfonate   disodium 5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-ylidene)-1,2-dihydro-3H-indol-3-one) disulfonate (c.i. 73015)   disodium 5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-ylidene)-1,2-dihydro-3H-indol-3-one)disulphonate   disodium 5,5'-indigotin disulfonate   disodium indigo-5,5-disulfonate   disodium salt of 1-indigotin-s,s'-disulfonic acid   disodium salt of 1-indigotin-S,S'-disulphonic acid   fd&c blue no. 2 (c.i. 73015 (Na))   food blue 1   food blue 1 disodium salt   food blue no. 1   indigo carmine (c.i. 73015 (Na)) 5,5- indigo disulfonic acid disodium salt (c.i. 73015 (Na))   indigotin-5,5'-disulfonic acid disodium salt   indigotine 1H- indole-5-sulfonic acid, 2-(1,3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-, disodium salt   natural blue 2   sodium 5,5'-indigotindisulfonate   sodium indigo-5,5'-bisulfonate   usacert blue no. 2   Articles: Info:Indigotin

Notes: indolesulfonic acid used as a dye in renal function testing for the detection of nitrates and chlorates, and in the testing of milk. Colour additive for food