EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

ci 16255
ponceau 4R

Supplier Sponsors

CAS Number: 2611-82-7Picture of molecule3D/inchi
Other(deleted CASRN):11138-24-2
ECHA EINECS - REACH Pre-Reg:220-036-2
FDA UNII: Z525CBK9PG
Beilstein Number:4122340
MDL:MFCD00004084
Molecular Weight:604.47797784
Formula:C20 H11 N2 Na3 O10 S3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:coloring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
EU SANCO Ponceau 4R, Cochineal Red A View - review
JECFA Food Additive: Ponceau 4R
GSFA Codex: Ponceau 4R (Cochineal red A) (124)
DG SANTE Food Additives:ponceau 4R
 
Physical Properties:
Appearance:reddish powder (est)
Assay: 85.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): 1.346 (est)
Soluble in:
 water, 8.00E+04 mg/L @ 25 °C (exp)
 alcohol, slightly
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data2
CosIng:cosmetic data
Cosmetic Uses: cosmetic colorants
hair dyeing agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
New Coccine Dye conte
Glentham Life Sciences
Ponceau 4R (C.I. 16255)
Kishi Kasei
Red No.102
Moellhausen
COLOUR RED PONCEAU E124
Rung International
Lake Ponceau 4R
Rung International
Ponceau 4R
Santa Cruz Biotechnology
For experimental / research use only.
New coccine
Sigma-Aldrich
For experimental / research use only.
Ponceau 4R
TCI AMERICA
For experimental / research use only.
Acid Red 18 >85.0%(E)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 > 8000 mg/kg
KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Food and Cosmetics Toxicology. Vol. 5, Pg. 187, 1967.

intraperitoneal-mouse LD50 1600 mg/kg
BEHAVIORAL: COMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Food and Cosmetics Toxicology. Vol. 5, Pg. 187, 1967.

oral-mouse LDLo 8000 mg/kg
Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979.

intraperitoneal-rat LD50 600 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: COMA
Food and Cosmetics Toxicology. Vol. 5, Pg. 187, 1967.

intravenous-rat LD50 1000 mg/kg
Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979.

unreported-rat LD50 2000 mg/kg
Nara Igaku Zasshi. Journal of the Nara Medical Association. Vol. 30, Pg. 179, 1979.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
coloring agents
Recommendation for ci 16255 usage levels up to:
 not for fragrance use.
 
Recommendation for ci 16255 flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the re-evaluation of Ponceau 4R (E 124) as a food additive
View page or View pdf

Assessment of the results of the study by McCann et al. (2007) on the effect of some colours and sodium benzoate on children’s behaviour [1] - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Food Contact Materials (AFC)
View page or View pdf

Statement on Allura Red AC and other sulphonated mono azo dyes authorised as food and feed additives
View page or View pdf

Refined exposure assessment for Ponceau 4R (E 124)
View page or View pdf

Safety and efficacy of ponceau 4R for cats, dogs and ornamental fish
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):2611-82-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :9570119
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
trisodium (8Z)-7-oxo-8-[(4-sulfonatonaphthalen-1-yl)hydrazinylidene]naphthalene-1,3-disulfonate
Chemidplus:0002611827
RTECS:QJ6530000 for cas# 2611-82-7
 
References:
 trisodium (8Z)-7-oxo-8-[(4-sulfonatonaphthalen-1-yl)hydrazinylidene]naphthalene-1,3-disulfonate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:2611-82-7
Pubchem (cid):9570119
Pubchem (sid):134981627
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C20344
HMDB (The Human Metabolome Database):HMDB29855
FooDB:FDB001076
Export Tariff Code:3204.12.5090
FDA Color Additive Status ListView
ChemSpider:View
Wikipedia:View
FAO:PONCEAU 4R
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 cosmetic colorants
 hair dyeing agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 acid brilliant scarlet 3R
 acid ponceau 4R
 acid red 18 (c.i. 16255)
 acid scarlet 3R
 brilliant ponceau 3R
 brilliant scarlet 3R
 c.i. 16255
 C.I. acid red 18, trisodium salt
 calcocid brilliant scarlet 3RN
 cochineal red A
 food red 7
7-hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-1,3-naphthalene disulfonic acid trisodium salt
7-hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-1,3-naphthalenedisulfon- ic acid, trisodium salt
7-hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-1,3-naphthalenedisulfonic acid trisodium salt
 naphthalene scarlet 4R
1,3-naphthalenedisulfonic acid, 7-hydroxy-8-((4-sulfo-1-naphthalenyl)azo)-, trisodium salt
 new coccine (c.i. 16255)
 ponceau 4R
 scarlet 4R
1-(4-sulpho-1-naphthylazo)-2-naphthol-6,8-disulphonic acid, trisodium salt
 trisodium (8Z)-7-oxo-8-[(4-sulfonatonaphthalen-1-yl)hydrazinylidene]naphthalene-1,3-disulfonate
 trisodium 1-(1-naphthyl azo)-2-hydroxynaphthalene-4',6,8-trisulfonate (c.i. 16255)
 victoria scarlet 3R
 
 
Notes:
Synthetic food colouring Because it is an azo dye, it may elicit intolerance in people allergic to salicylates (aspirin). Additionally, it is a histamine liberator, and may intensify symptoms of asthma.; Ponceau 4R (also known as Food Red 7[citation needed], C.I. 16255[citation needed], Cochineal Red A[citation needed], New Coccine, Acid Red 18, SX purple[citation needed]) is a synthetic colourant that may be added to foods to induce a colour change. It is denoted by E Number E124, and has the capacity for inducing an allergic reaction. Its chemical name is trisodium salt of 1-(4-sulpho-1-napthylazo)- 2-napthol- 6,8-disulphonic acid.; Ponceau 4R is a red azo dye usually synthesized from coal tar which can be used in a variety of food products.
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