disodium EDTA
sodium N,N'-ethane-1,2-diylbis(N-(carboxymethyl)glycinate)

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  05-00205 EDETATE DISODIUM DIHYDRATE

Name: disodium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate CAS Number: 139-33-3 3D/inchi Other(deleted CASRN): 104244-09-9 ECHA EINECS - REACH Pre-Reg: 205-358-3 FDA UNII: 8NLQ36F6MM Beilstein Number: 3822669 MDL: MFCD00070672 Molecular Weight: 336.20871856 Formula: C10 H14 N2 Na2 O8 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:sequestrant, antioxidant synergist, preservative   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   FDA/DG SANTE Petitions, Reviews, Notices: GRN 363 Calcium disodium ethylenediaminetetraacetic acid (EDTA) and disodium EDTA View - notice PDF JECFA Food Additive: Disodium Ethylenediaminetetraacetate GSFA Codex: Disodium ethylenediaminetetraacetate (386) FDA Mainterm (SATF): 139-33-3 ; EDTA, DISODIUM FDA Regulation: FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.200 Certain other canned vegetables. FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings Sec. 169.115 French dressing. FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings Sec. 169.140 Mayonnaise. FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings Sec. 169.150 Salad dressing. FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart B--Food Preservatives Sec. 172.120 Calcium disodium EDTA. FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart B--Food Preservatives Sec. 172.135 Disodium EDTA. FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart B--Substances for Use Only as Components of Adhesives Sec. 175.105 Adhesives. FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS Subpart B--Substances for Use Only as Components of Paper and Paperboard Sec. 176.150 Chelating agents used in the manufacture of paper and paperboard. FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS Subpart B--Substances for Use Only as Components of Paper and Paperboard Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1200 Cellophane. FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS Subpart B--Substances Utilized To Control the Growth of Microorganisms Sec. 178.1010 Sanitizing solutions. FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS Subpart D--Certain Adjuvants and Production Aids Sec. 178.3570 Lubricants with incidental food contact. FDA PART 573 -- FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS Subpart B--Food Additive Listing Sec. 573.360 Disodium EDTA. FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION Subpart A--Foods Sec. 73.1 Diluents in color additive mixtures for food use exempt from certification.   Physical Properties: Appearance: white crystalline powder (est) Assay: 99.00 to 100.00 Food Chemicals Codex Listed: No Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est) Soluble in:   water, 1e+006 mg/L @ 25 °C (est) Insoluble in:   alcohol   Organoleptic Properties: Odor Description:at 100.00 %. odorless Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: chelating agents viscosity controlling agents   Suppliers: American Elements Disodium Dihydrogen Ethylenediaminetetraacetate Solution 99% Odor: characteristic Use: Disodium Dihydrogen Ethylenediaminetetraacetate Solution is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. BOC Sciences For experimental / research use only. Ethylenediaminetetraacetic acid disodium salt Charkit Chemical DISODIUM EDTA, USP Connect Chemicals Ethylenediaminetetraacetic acid disodium salt (EDTA 2Na) Odor: characteristic Use: Ethylenediaminetetraacetic acid disodium salt (EDTA 2Na) is used in detergents, liquid soap, shampoo, agricultural chemicals, fixer solution for development of color film, water cleaner, pH modifier. When stating the redox reaction for the polymerization of butyl benzene rubber, it is used as part of activator for the control of polymerization speed. ECSA Chemicals EDTA DISODIUM SALT POWDER ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY Graham Chemical Disodium Ethylenediamine, Tetraacetate Dihydrate Indis NV For experimental / research use only. Disodium Edta Kraft Chemical Disodium EDTA Penta International EDETATE DISODIUM DIHYDRATE Prinova Edta Na2p Disodium Santa Cruz Biotechnology For experimental / research use only. Ethylenediaminetetraacetic acid disodium salt solution Sigma-Aldrich For experimental / research use only. Ethylenediaminetetraacetic acid disodium salt solution for molecular biology, 0.5 M in H2O, DNase, RNase, NICKase and protease, none detected   Safety Information:   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-rat LD50 2000 mg/kg Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 27, Pg. 465, 1968. oral-rabbit LD50 2300 mg/kg Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 113, 1956. intravenous-rabbit LD50 47 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 113, 1956. oral-mouse LD50 2050 mg/kg Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 126S, 1956. intravenous-mouse LD50 56 mg/kg U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03781 intraperitoneal-mouse LD50 260 mg/kg Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 126S, 1956. Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: sequestrant, antioxidant synergist, preservative Recommendation for disodium EDTA usage levels up to:   not for fragrance use.   Recommendation for disodium EDTA flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA GENetic TOXicology:Search EPA Substance Registry Services (TSCA):139-33-3 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :8759 National Institute of Allergy and Infectious Diseases:Data WGK Germany:2 disodium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate Chemidplus:0000139333   References:   disodium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 139-33-3 Pubchem (cid): 8759 Pubchem (sid): 134974234   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View FDA Indirect Additives used in Food Contact Substances: View CHEMBL: View KEGG (GenomeNet): D03945 HMDB (The Human Metabolome Database): Search FooDB: FDB015445 FDA Listing of Food Additive Status: View ChemSpider: View Wikipedia: View Formulations/Preparations: •the cosmetic-grade material contains a minimum of 99.0% tetrasodium edta as na4edta.2h2o •anhydrous or dihydrate.   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms:   disodium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate   disodium 2,2'-({2-[bis(carboxymethyl)amino]ethyl}imino)diacetate   disodium 2,2'-{ethane-1,2-diylbis[(carboxymethyl)imino]}diacetate   disodium dihydrogen ethylene diamine tetraacetate   disodium edetate   disodium EDTA, anhydrous   disodium ethylenediaminetetraacetate   edetate disodium   edetate sodium   sodium N,N'-ethane-1,2-diylbis(N-(carboxymethyl)glycinate)   Articles: Info:EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS

Notes: Preservative and sequestrant in foods Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is a polyamino carboxylic acid and a colourless, water-soluble solid. Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve limescale. Its usefulness arises because of its role as a hexadentate ("six-toothed") ligand and chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+. After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity. EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA. (Wikipedia) Chelating agent used in food processing Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is a polyamino carboxylic acid and a colourless, water-soluble solid. Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve limescale. Its usefulness arises because of its role as a hexadentate ("six-toothed") ligand and chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+. After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity. EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA. (Wikipedia) Sequestrant, preservative and discolouration inhibitor for foods Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is a polyamino carboxylic acid and a colourless, water-soluble solid. Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve limescale. Its usefulness arises because of its role as a hexadentate ("six-toothed") ligand and chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+. After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity. EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA. (Wikipedia)