EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

laevo-methionine
L-methionine

Supplier Sponsors

CAS Number: 63-68-3Picture of molecule3D/inchi
Other(deleted CASRN):24425-78-3
ECHA EINECS - REACH Pre-Reg:200-562-9
FDA UNII: AE28F7PNPL
Nikkaji Web:J9.174J
Beilstein Number:1722294
MDL:MFCD00063097
XlogP3:-1.90 (est)
Molecular Weight:149.21307000
Formula:C5 H11 N O2 S
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:special dietary and nutritional additives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
DG SANTE Food Flavourings:17.027 L-methionine
FEMA Number:3301 L-methionine
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):63-68-3 ; L-METHIONINE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart D--Special Dietary and Nutritional Additives
Sec. 172.320 Amino acids.
 
Physical Properties:
Appearance:white crystalline solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 283.00 to 284.00 °C. @ 760.00 mm Hg
Boiling Point: 306.00 to 308.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.000170 mmHg @ 25.00 °C. (est)
Flash Point: 282.00 °F. TCC ( 138.89 °C. )
logP (o/w): 0.217 (est)
Soluble in:
 water, 2.574e+004 mg/L @ 25 °C (est)
 water, 5.66E+04 mg/L @ 25 °C (exp)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
AIDP
L-Methionine 98.5%
Ajinomoto USA
L-Methionine
Flavor: characteristic
L-methionine is an essential amino acid. The human body cannot manufacture this amino acid and must obtain it from the daily diet. The male adult’s daily requirement is 13 mg per kg of body weight. L-methionine deficiency is unlikely as it is readily available from meat, fish, dairy and other high protein foods.
Alfa Biotechnology
For experimental / research use only.
L-Methionine 98%
Atlantic Chemicals
L-Methionine
AuNutra® Industries
L-Methionine
Bio Springer
Springer® 4000 yeast extracts
Flavor: characteristic
The Springer® 4000 yeast extracts provide Kokumi taste, or mouthfullness, thanks to the naturally occurring sulfur amino acids and peptides they contain. They provide intense poultry stock flavour and enhance meat and cheese flavours. These glutathione-rich extracts work well on their own or in synergy with one of our Springer® yeast extracts. Because they are naturally rich in sulfur amino acids, Springer® 4000 yeast extracts eliminate the need for adding individual sulfur amino acids during flavour production.
BOC Sciences
For experimental / research use only.
H-Met-OH >98%
Charkit Chemical
METHIONINE, L- NATURAL
Charkit Chemical
METHIONINE, L-
ExtraSynthese
For experimental / research use only.
L-Methionine
Glentham Life Sciences
L-Methionine, 99%, GlenCell, suitable for cell culture, Ph. Eur., USP grade
Glentham Life Sciences
L-Methionine
sds
Graham Chemical
L-Methionine
Indis NV
For experimental / research use only.
L-Methionine
Jiangyin Healthway
L-Methionine
New functional food ingredients
Penta International
L-METHIONINE USP
Penta International
L-METHIONINE
Prinova
L-Methionine USP
Sigma-Aldrich
For experimental / research use only.
L-Methionine reagent grade, ≥98% (TLC)
TCI AMERICA
For experimental / research use only.
L-Methionine >99.0%(T)
sds
Tianjin Talent Chemical
Methionine (DL / L)
United International
L-Methionine Nat.
Zhong Ya Chemical
L-Methionine
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 > 9500 mg/kg
Progress in Mutation Research. Vol. 1, Pg. 682, 1981.

intraperitoneal-rat LD50 4328 mg/kg
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Archives of Biochemistry and Biophysics. Vol. 58, Pg. 253, 1955.

oral-rat LD50 36000 mg/kg
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(6), Pg. 20, 1983.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
special dietary and nutritional additives
Recommendation for laevo-methionine usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 5
Click here to view publication 5
 average usual ppmaverage maximum ppm
baked goods: -50.00000
beverages(nonalcoholic): -50.00000
beverages(alcoholic): --
breakfast cereal: -50.00000
cheese: --
chewing gum: --
condiments / relishes: -50.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: -50.00000
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -50.00000
milk products: -50.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -50.00000
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Amino acids from chemical group 34 Flavouring Group Evaluation 26, Revision 1 - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 29 (FGE29)[1] - Substance from the priority list: Vinylbenzene from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 79, (FGE.79)[1] - Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008)
View page or View pdf

Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1]
View page or View pdf

Scientific Opinion on the safety and efficacy of L-methionine produced by Escherichia coli (KCCM 11252P) and Escherichia coli (KCCM 11340P) for all animal species
View page or View pdf

Scientific Opinion on the safety and efficacy of the use of amino acids (chemical group 34) when used as flavourings for all animal species
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 49, Revision 1 (FGE.49Rev1): xanthine alkaloids from the priority list
View page or View pdf

Safety and efficacy of l-methionine produced by fermentation with Corynebacterium glutamicum KCCM 80184 and Escherichia coli KCCM 80096 for all animal species
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):63-68-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6137
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
(2S)-2-amino-4-methylsulfanylbutanoic acid
Chemidplus:0000063683
EPA/NOAA CAMEO:hazardous materials
RTECS:PD0457000 for cas# 63-68-3
 
References:
 (2S)-2-amino-4-methylsulfanylbutanoic acid
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:63-68-3
Pubchem (cid):6137
Pubchem (sid):134971809
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
Metabolomics Database:Search
UM BBD:Search
KEGG (GenomeNet):C00073
HMDB (The Human Metabolome Database):HMDB00696
FooDB:FDB012683
YMDB (Yeast Metabolome Database):YMDB00318
Export Tariff Code:2930.40.0000
FDA Listing of Food Additive Status:View
MedlinePlusSupp:View
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•nf, feed 98% •usp and fcc grades; 99% feed grade •racemate mixture of d- and l- methionine
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
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 goosefoot leaf
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 gourd calabash gourd fruit
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 kohlrabi stem
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 leek wild leek plant
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 lentil sprout
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 lettuce lamb's lettuce plant
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 lettuce leaf
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 lime fruit
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 lotus indian lotus rhizome
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 lotus indian lotus seed
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 lupine white lupine seed
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 poppy opium poppy seed
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 potato sweet potato root
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 potato tuber
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 radish root
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 rice plant
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 rosemary leaf
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 rye seed
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 soybean seed
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 soybean shoot
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 spearmint leaf
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 spinach indian spinach leaf
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 spinach leaf
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 wheat seed
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 yam mountain yam root
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Synonyms:
(S)-2-amino-4-(methyl thio) butanoic acid
(S)-2-amino-4-(methylmercapto)butyric acid
(2S)-2-amino-4-(methylsulfanyl)butanoic acid
(S)-2-amino-4-(methylthio)-butanoic acid
(S)-2-amino-4-(methylthio)butanoic acid
L-2-amino-4-(methylthio)butanoic acid
(S)-2-amino-4-(methylthio)butyric acid
L-2-amino-4-(methylthio)butyric acid
2-amino-4-(methylthio)butyric acid, (S)-
(S)-2-amino-4-methyl thiobutanoic acid
(2S)-2-amino-4-methylsulfanylbutanoic acid
2-amino-4-methylthiobutanoic acid (S)-
L-2-amino-4methylthiobutyric acid
L-a-amino-g-methylmercaptobutyric acid
laevo-alpha-amino-gamma-methyl mercaptobutyric acid
laevo-alpha-amino-gamma-methyl thiobutyric acid
laevo(-)-amino-gamma-methyl thiobutyric acid
L-alpha-amino-gamma-methylmercaptobutyric acid
L-alpha-amino-gamma-methylthiobutyric acid
 butanoic acid, 2-amino-4-(methylthio)-, (S)-
 cymethion
 liquimeth
(L)-methionine
(S)-methionine
(S)-(-)-methionine
(S)-(+)-methionine
L-methionine
L-(-)-methionine
laevo-(-)-methionine
S-methionine
 methionine L-
L-methionine USP
 methionine, L-
L-methioninum
laevo-methioninum
laevo-gamma-methyl thio-alpha-aminobutyric acid
S-methyl-laevo-homocysteine
L-gamma-methylthio-alpha-aminobutyric acid
 

Articles:

PubMed:Olfactory perception of 6 amino acids by human subjects.
J-Stage:Folic Acid Fortification Ameliorates Hyperhomocysteinemia Caused by a Vitamin B6-Deficient Diet Supplemented with L-Methionine
PubMed:Utilization of L-methionine sulfoxide by the rat.
J-Stage:Involvement of 5-Methyltetrahydrofolate in the Amelioration of Hyperhomocysteinemia Caused by Vitamin B6 Deficiency and L-Methionine Supplementation
PubMed:Kokumi-active glutamyl peptides in cheeses and their biogeneration by Penicillium roquefortii.
PubMed:Heterologous production of methionine-gamma-lyase from Brevibacterium linens in Lactococcus lactis and formation of volatile sulfur compounds.
PubMed:Production of the aroma chemicals 3-(methylthio)-1-propanol and 3-(methylthio)-propylacetate with yeasts.
PubMed:Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol.
PubMed:Cloning and characterization of two Lactobacillus casei genes encoding a cystathionine lyase.
PubMed:YtjE from Lactococcus lactis IL1403 Is a C-S lyase with alpha, gamma-elimination activity toward methionine.
PubMed:Involvement of a branched-chain aminotransferase in production of volatile sulfur compounds in Yarrowia lipolytica.
PubMed:Development and validation of a plate technique for screening of microorganisms that produce volatile sulfur compounds.
PubMed:Production of volatile organic sulfur compounds (VOSCs) by basidiomycetous yeasts.
PubMed:Identification and functional analysis of the gene encoding methionine-gamma-lyase in Brevibacterium linens.
PubMed:Sulfur metabolism in bacteria associated with cheese.
PubMed:Purification and characterization of L-methionine gamma-lyase from brevibacterium linens BL2
PubMed:Conversion of methionine to thiols by lactococci, lactobacilli, and brevibacteria
PubMed:Purification and Characterization of Cystathionine (gamma)-Lyase from Lactococcus lactis subsp. cremoris SK11: Possible Role in Flavor Compound Formation during Cheese Maturation.
PubMed:Dietary l-methionine supplementation mitigates gamma-radiation induced global DNA hypomethylation: Enhanced metabolic flux towards S-adenosyl-l-methionine (SAM) biosynthesis increases genomic methylation potential.
PubMed:Targeting Cystalysin, a Virulence Factor of Treponema denticola-Supported Periodontitis.
PubMed:Fast quantification of S-adenosyl-L-methionine in dietary health products utilizing reversed-phase high-performance liquid chromatography: teaching an old method new tricks.
PubMed:Comparative performance of S-adenosyl-L-methionine biosynthesis and degradation in Pichia pastoris using different promoters and novel consumption inhibitors.
PubMed:Development of a minimal chemically defined medium for Ketogulonicigenium vulgare WSH001 based on its genome-scale metabolic model.
PubMed:Identification and active site analysis of the 1-aminocyclopropane-1-carboxylic acid oxidase catalysing the synthesis of ethylene in Agaricus bisporus.
PubMed:Nonchromatographic speciation of selenium in edible oils using dispersive liquid-liquid microextraction and electrothermal atomic absorption spectrometry.
PubMed:Simultaneous quantitation and identification of organic and inorganic selenium in diet supplements by liquid chromatography with tandem mass spectrometry.
PubMed:Obesity-related metabolomic analysis of human subjects in black soybean peptide intervention study by ultraperformance liquid chromatography and quadrupole-time-of-flight mass spectrometry.
PubMed:Digestive recovery of sulfur-methyl-L-methionine and its bioaccessibility in Kimchi cabbages using a simulated in vitro digestion model system.
PubMed:Effect of metformin on the urinary metabolites of diet-induced-obese mice studied by ultra performance liquid chromatography coupled to time-of-flight mass spectrometry (UPLC-TOF/MS).
PubMed:Enhancing the production of S-adenosyl-L-methionine in Pichia pastoris GS115 by metabolic engineering.
PubMed:Genetic Modification and Bioprocess Optimization for S-Adenosyl-L-methionine Biosynthesis.
PubMed:Selenium and zinc internalized by Lactobacillus buchneri Lb26 (DSM 16341) and Bifidobacterium lactis Bb1 (DSM 17850): improved bioavailability using a new biological approach.
PubMed:Selenium-enriched Candida utilis: efficient preparation with l-methionine and antioxidant capacity in rats.
PubMed:Reconstruction and analysis of a genome-scale metabolic model of the vitamin C producing industrial strain Ketogulonicigenium vulgare WSH-001.
PubMed:Activation of Nrf2 is required for up-regulation of the π class of glutathione S-transferase in rat primary hepatocytes with L-methionine starvation.
PubMed:Protection of L-methionine against H₂O₂-induced oxidative damage in mitochondria.
PubMed:Dietary supplement drug therapies for depression.
PubMed:Epigenetics and breast cancers.
PubMed:Epigenetic mechanisms in anti-cancer actions of bioactive food components--the implications in cancer prevention.
PubMed:Volatile sulphur compounds and pathways of L-methionine catabolism in Williopsis yeasts.
PubMed:A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension.
PubMed:Cloning of metK from Actinoplanes teichomyceticus ATCC31121 and effect of its high expression on antibiotic production.
PubMed:New insights into the metabolism of organomercury compounds: mercury-containing cysteine S-conjugates are substrates of human glutamine transaminase K and potent inactivators of cystathionine γ-lyase.
PubMed:Dietary self-selection of protein-unbalanced diets supplemented with three essential amino acids in Nile tilapia.
PubMed:Gelatin enhances 2-keto-L-gulonic acid production based on Ketogulonigenium vulgare genome annotation.
PubMed:Volatile sulphur compounds-forming abilities of lactic acid bacteria: C-S lyase activities.
PubMed:Biosynthesis of methoxypyrazines: elucidating the structural/functional relationship of two Vitis viniferaO-methyltransferases capable of catalyzing the putative final step of the biosynthesis of 3-alkyl-2-methoxypyrazine.
PubMed:Olfactory sensitivity to amino acids in the blackspot sea bream (Pagellus bogaraveo): a comparison between olfactory receptor recording techniques in seawater.
PubMed:Nutritional and medicinal aspects of D-amino acids.
PubMed:HC-Pro silencing suppressor significantly alters the gene expression profile in tobacco leaves and flowers.
PubMed:Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
PubMed:Selenium accumulation in coturnix quail fed seleno-L-methionine.
PubMed:Production of flavour-active methionol from methionine metabolism by yeasts in coconut cream.
PubMed:Investigation of reactive alpha-dicarbonyl compounds generated from the Maillard reactions of L-methionine with reducing sugars via their stable quinoxaline derivatives.
PubMed:Metabolic pathways and fermentative production of L-aspartate family amino acids.
PubMed:Olfactory perception of 6 amino acids by human subjects.
PubMed:Methionine restriction up-regulates the expression of the pi class of glutathione S-transferase partially via the extracellular signal-regulated kinase-activator protein-1 signaling pathway initiated by glutathione depletion.
PubMed:Competition between selenomethionine and methionine absorption in the intestinal tract of green sturgeon (Acipenser medirostris).
PubMed:Heterologous production of methionine-gamma-lyase from Brevibacterium linens in Lactococcus lactis and formation of volatile sulfur compounds.
PubMed:Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS.
PubMed:Dietary crude protein has minimal effect on the activity of selected enzymes of methionine catabolism in kittens fed diets near-limiting in methionine.
PubMed:[Methionine dependency of cancer cells: a new therapeutic approach?].
PubMed:Potential role of cysteine and methionine in the protection against hormonal imbalance and mutagenicity induced by furazolidone in female rats.
PubMed:The transfer of different forms of 35S to goat milk.
PubMed:2-keto-4-(methylthio)butyric acid (keto analog of methionine) is a safe and efficacious precursor of L-methionine in chicks.
PubMed:Gene expression and biochemical analysis of cheese-ripening yeasts: focus on catabolism of L-methionine, lactate, and lactose.
PubMed:Molecular and functional characterization of Lactobacillus sanfranciscensis strains isolated from sourdoughs.
PubMed:Kluyveromyces lactis and Saccharomyces cerevisiae, two potent deacidifying and volatile-sulphur-aroma-producing microorganisms of the cheese ecosystem.
PubMed:Protease and esterase activity of staphylococci.
PubMed:Improved L-threonine production of Escherichia coli mutant by optimization of culture conditions.
PubMed:Poly-beta-hydroxybutyrate accumulation in Nostoc muscorum: effects of metabolic inhibitors.
PubMed:Water-soluble vitamins.
PubMed:Cystathionine gamma-lyase contributes to selenomethionine detoxification and cytosolic glutathione peroxidase biosynthesis in mouse liver.
PubMed:The role of prey nutritional status in governing protozoan nitrogen regeneration efficiency.
PubMed:Developmental responses of a terrestrial insect detritivore, Megaselia scalaris (Loew) to four selenium species.
PubMed:Effects of dietary selenomethionine on larval rainbow trout (Oncorhynchus mykiss).
PubMed:Chlorogenic acid moderately decreases the quality of whey proteins in rats.
PubMed:Effect of adding dietary L-lysine, L-threonine and L-methionine to a low gluten diet on urea synthesis in rats.
PubMed:Aberrant transcription of FHIT gene in intrahepatic cholangiocellular carcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
PubMed:Transfer of selenium from prey to predators in a simulated terrestrial food chain.
PubMed:The influence of dietary vitamin E, fat, and methionine on blood cholesterol profile, homocysteine levels, and oxidizability of low density lipoprotein in the gerbil.
PubMed:Trophic and maternal transfer of selenium in brown house snakes (Lamprophis fuliginosus).
PubMed:NMR regulatory analysis: determination and characterization of S-adenosyl-L-methionine in dietary supplements.
PubMed:Influences of different selenium species on the uptake and assimilation of Hg(II) and methylmercury by diatoms and green mussels.
PubMed:Pharmacokinetics, methionine depletion, and antigenicity of recombinant methioninase in primates.
PubMed:Methioninase and selenomethionine but not Se-methylselenocysteine generate methylselenol and superoxide in an in vitro chemiluminescent assay: implications for the nutritional carcinostatic activity of selenoamino acids.
PubMed:Screening crucifer seeds as sources of specific intact glucosinolates using ion-pair high-performance liquid chromatography negative ion electrospray mass spectrometry.
PubMed:Catabolism of volatile sulfur compounds precursors by Brevibacterium linens and Geotrichum candidum, two microorganisms of the cheese ecosystem.
PubMed:Characterization of an inducible chlorophenol O-methyltransferase from Trichoderma longibrachiatum involved in the formation of chloroanisoles and determination of its role in cork taint of wines.
PubMed:Review article: Nutritional therapy in alcoholic liver disease.
PubMed:Betaine supplementation lowers plasma homocysteine in healthy men and women.
PubMed:Soy protein isolate enhances hepatic copper accumulation and cell damage in LEC rats.
PubMed:Enzymatic synthesis and characterization of l-methionine and 2-hydroxy-4-(methylthio)butanoic acid (HMB) co-oligomers.
PubMed:Hepatic glycine N-methyltransferase is up-regulated by excess dietary methionine in rats.
PubMed:Effects of soy protein supplemented with methionine on blood lipids and adiposity of rats.
PubMed:Peptidolytic, esterolytic and amino acid catabolic activities of selected bacterial strains from the surface of smear cheese.
PubMed:Vitamin A and its derivatives induce hepatic glycine N-methyltransferase and hypomethylation of DNA in rats.
PubMed:Sulfur amino acid deficiency depresses brain glutathione concentration.
PubMed:Sulfur compound production by Geotrichum candidum from L-methionine: importance of the transamination step.
PubMed:Efficacy of the dietary supplement S-adenosyl-L-methionine.
PubMed:Effect of vitamin B6 deficiency on the synthesis and accumulation of S-adenosylhomocysteine and S-adenosylmethionine in rat tissues.
PubMed:Amino acid catabolism in cheese-related bacteria: selection and study of the effects of pH, temperature and NaCl by quadratic response surface methodology.
PubMed:Changes in nitrogen compounds in must and wine during fermentation and biological aging by flor yeasts.
PubMed:Retinoid compounds activate and induce hepatic glycine N-methyltransferase in rats.
PubMed:Lactobacillus casei and Lactobacillus plantarum initiate catabolism of methionine by transamination.
PubMed:L-methionine and naltrexone for insomnia.
PubMed:Effect of supplementation of dry cat food with D,L-methionine and ammonium chloride on struvite activity product and sediment in urine.
PubMed:Carbohydrate and amino acid degradation pathways in L-methionine/D-[13C] glucose model systems.
PubMed:Characterization of monocot and dicot plant S-adenosyl-l-methionine decarboxylase gene families including identification in the mRNA of a highly conserved pair of upstream overlapping open reading frames.
PubMed:Antisense modulation of 5,10-methylenetetrahydrofolate reductase expression produces neural tube defects in mouse embryos.
PubMed:Polyamines and thiols in the cytoprotective effect of L-cysteine and L-methionine on carbon tetrachloride-induced hepatotoxicity.
PubMed:Depletion of delta 9 desaturase (EC 1.14.99.5) activity in lactating rat during protein restriction.
PubMed:Olfactory discrimination of amino acids in brown bullhead catfish.
PubMed:Biotransformation of protocatechuic aldehyde and caffeic acid to vanillin and capsaicin in freely suspended and immobilized cell cultures of Capsicum frutescens.
PubMed:Synthesis and characterisation of a new class of stable S-adenosyl-L-methionine salts.
PubMed:Regulation of L-methionine and L-lysine uptake in chicken jejunal brush-border membrane by dietary methionine.
PubMed:Sulfur metabolism in bacteria associated with cheese.
PubMed:Rumen-protected methionine fed to dairy cows: bioavailability and effects on plasma amino acid pattern and plasma metabolite and insulin concentrations.
PubMed:Influence of S-adenosyl-L-methionine on chronic mild stress-induced anhedonia in castrated rats.
PubMed:Methylation of tea catechins by rat liver homogenates.
PubMed:Nutritional effects of a D-methionine-containing solution on AH109A hepatoma-bearing rats.
PubMed:Conversion of methionine to thiols by lactococci, lactobacilli, and brevibacteria
PubMed:The relative effectiveness of 2-hydroxy-4-(methylthio) butanoic acid and DL-methionine in young swine.
PubMed:Characterization of S-adenosyl-L-methionine:(iso)eugenol O-methyltransferase involved in floral scent production in Clarkia breweri.
PubMed:The hog intestinal mucosa acylase I: subcellular localization, isolation, kinetic studies and biological function.
PubMed:Dietary sulphur amino acid adequacy influences glutathione synthesis and glutathione-dependent enzymes during the inflammatory response to endotoxin and tumour necrosis factor-alpha in rats.
PubMed:Enhanced anticancer effect of vincristine with methionine infusion after methionine-depleting total parenteral nutrition in tumor-bearing rats.
PubMed:Lack of attenuation of valproic acid-induced embryotoxicity by compounds involved in one-carbon transfer reactions.
PubMed:Methionine deficiency decreases protein accretion and synthesis but not tRNA acylation in muscles of chicks.
PubMed:Tracer kinetic studies on a methionine-supplemented soy-based infant formula using 1-13C- and 15N-methionine as tracers.
PubMed:Supplemental dietary cystine elevates kidney metallothionein in rats by a mechanism involving altered zinc metabolism.
PubMed:Rats fed a low protein diet supplemented with sulfur amino acids have increased cysteine dioxygenase activity and increased taurine production in hepatocytes.
PubMed:Stability-indicating proton nuclear magnetic resonance spectroscopic method for determination of S-adenosyl-L-methionine in tablets.
PubMed:The protein quality of some enteral products is inferior to that of casein as assessed by rat growth methods and digestibility-corrected amino acid scores.
PubMed:Low methionine ingestion by rats extends life span.
PubMed:Efficiency of dietary methionine utilization by young pigs.
PubMed:Prolonged acetaminophen ingestion by mice fed a methionine-limited diet does not affect iron-induced liver lipid peroxidation or S-adenosylmethionine.
PubMed:The effect of blood sample aging and food consumption on plasma total homocysteine levels.
PubMed:Decreased glutathione S-transferase activity in mice livers by acute treatment with lead, independent of alteration in glutathione content.
PubMed:Formation, nutritional value, and safety of D-amino acids.
PubMed:Prolonged survival of female AKR mice fed diets supplemented with methionine and choline.
PubMed:Effects of feeding rats low protein diets containing casein or soy protein isolate supplemented with methionine or oligo-L-methionine.
PubMed:Effects of elevated foodborne selenium on growth and reproduction of the fathead minnow (Pimephales promelas).
PubMed:Hepatic glutathione metabolism in mice acutely treated with lead acetate.
PubMed:[Nutritional recovery in marasmus using soy formula enriched with L-methionine].
PubMed:Effect of EDTA and zinc-methionine complex on zinc absorption by rat intestine.
PubMed:Effect of supplementing low protein diets with the limiting amino acids on the excretion of N1-methylnicotinamide and its pyridones in rats.
PubMed:[Cell growth of skeletal muscle as an indicator of protein requirements of the adult rat].
PubMed:Effects of prolonged acetaminophen ingestion and dietary methionine on mouse liver glutathione.
PubMed:Methionine-induced acidosis in the weanling rat.
PubMed:Effect of methionine supplementation of a soy protein isolate on short-term nitrogen balance in young women.
PubMed:Comparative metabolism of L-methionine, DL-methionine and DL-2-hydroxy 4-methylthiobutanoic acid by broiler chicks.
PubMed:Response of broilers to DL-methionine hydroxy analog free acid, DL-methionine, and L-methionine.
PubMed:Development of a basal diet to study broiler chicken responses to the sulfur-containing amino acids and sodium sulfate.
PubMed:The utilization and safety of isomeric sulfur-containing amino acids in mice.
PubMed:Comparative absorption of 2-hydroxy-4-(methylthio)-butanoic acid and L-methionine in the broiler chick.
PubMed:Portal and vena caval plasma methionine concentrations in young pigs administered L-methionine, N-acetyl-L-methionine and N-acetyl-D-methionine.
PubMed:Methionine peptides as potential food supplements: efficacy and susceptibility to Maillard browning.
PubMed:Evaluation of the protein quality of an isolated soy protein in young men: relative nitrogen requirements and effect of methionine supplementation.
PubMed:Methionine requirement of kittens given amino acid diets containing adequate cystine.
PubMed:Amino acid-enriched plasteins: a source of limiting amino acids for the weanling rat.
PubMed:Plasma and urinary methionine levels in one-year-old infants after oral loading with L-methionine and N-acetyl-L-methionine.
PubMed:Inhibition of nitrosation of amines by thiols, alcohols and carbohydrates.
PubMed:Intestinal transport of amino acids in protein-deficient rats and the effect of rehabilitation using a casein diet.
PubMed:Fetal growth retardation induced by dietary imbalance of threonine and dispensable amino acids, with adequate energy and protein-equivalent intakes, in pregnant rats.
PubMed:Effectiveness of the free acid of methionine hydroxy analogue as a methionine supplement in broiler diets.
PubMed:Growth and liver enzyme response in growing rats to graded levels of methionine plus cystine in fortified-barley diets. Response at constant methionine:cystine.
PubMed:Methionine fortification of a soy protein formula fed to infants.
PubMed:Efficacy of the D- and L-isomers of N-acetylmethionine for chicks fed diets containing either crystalline amino acids or intact protein.
PubMed:Effect of diets supplemented with amino acids on intestinal sucrase and leucine aminopeptidase activities in rats.
PubMed:Plasma amino acid response to single test meals in humans. III. Supplementary effect of dried skim milk and L-methionine on a vegetable protein mixture.
PubMed:[Induction of tyrosine aminotransferase (EC 2.5.1.5) by nicotinamide in rat liver (author's transl)].
PubMed:Factors affecting methionine toxicity and its alleviation in the chick.
PubMed:Nutritional improvement of food proteins by enzymatic modification, especially by plastein synthesis reaction.
PubMed:Bioavailability of acetylated derivatives of methionine, threonine, and lysine.
PubMed:[The influence of the quality of proteins in fluoride bone fixation].
PubMed:Chemosensory tracking of scent trails by the planktonic shrimp Acetes sibogae australis.
PubMed:Nitrogen retention in men fed isolated soybean protein supplemented with L-methionine, D-methionine, N-acetyl-L-methionine, or inorganic sulfate.
PubMed:Utilization of L-methionine sulfoxide, L-methionine sulfone and cysteic acid by the weanling rat.
PubMed:Amino acid transport inhibition: brain and behavioral correlates.
PubMed:Effects of amino acid imbalance and protein content of diets on food intake and preference of young, adult, and diabetic rats.
PubMed:Cystathionine excretion in relation to vitamin B-6 nutriture of rats: strain differences and effects of DL- or L-methionine supplementation.
PubMed:Comparative value of L-, and D-methionine supplementation of an oat-based diet for humans.
PubMed:Acetylmethionine as a source of methionine for the rat.
 
Notes:
a sulfur containing essential amino acid that is important in many body functions. it is a chelating agent for heavy metals. Dietary supplement and nutrient Methionine is an alpha-amino acid with the chemical formula HO2CCH(NH2)CH2CH2SCH3. This essential amino acid is classified as nonpolar. (Wikipedia)
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