EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro-glutamic acid
(R)-2-aminopentanedioic acid

Supplier Sponsors

Name:(2R)-2-aminopentanedioic acid
CAS Number: 6893-26-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:230-000-8
FDA UNII: Q479989WEA
Nikkaji Web:J9.214B
Beilstein Number:1723800
MDL:MFCD00063112
XlogP3:-3.70 (est)
Molecular Weight:147.13053000
Formula:C5 H9 N O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:colorless crystals (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 201.00 to 202.00 °C. @ 760.00 mm Hg
Boiling Point: 333.00 to 334.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000025 mmHg @ 25.00 °C. (est)
Flash Point: 312.00 °F. TCC ( 155.70 °C. ) (est)
logP (o/w): -0.969 (est)
Soluble in:
 water, 8880 mg/L @ 25 °C (exp)
Insoluble in:
 alcohol
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
D-(-)-Glutamic acid >98.0%(T)
Carbosynth
For experimental / research use only.
Glutamic acid
Changzhou Longo Chemical
D-Glutamic Acid
Glentham Life Sciences
D-Glutamic Acid
sds
Penta International
D-GLUTAMIC ACID
Sigma-Aldrich: Sigma
For experimental / research use only.
D-Glutamic acid ≥99% (TLC)
sds
TCI AMERICA
For experimental / research use only.
D-Glutamic Acid >98.0%(T)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for dextro-glutamic acid usage levels up to:
 not for fragrance use.
 
Recommendation for dextro-glutamic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Re-evaluation of glutamic acid (E 620), sodium glutamate (E 621), potassium glutamate (E 622), calcium glutamate (E 623), ammonium glutamate (E 624) and magnesium glutamate (E 625) as food additives
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):6893-26-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23327
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
(2R)-2-aminopentanedioic acid
Chemidplus:0006893261
 
References:
 (2R)-2-aminopentanedioic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):23327
Pubchem (sid):134987070
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C00217
HMDB (The Human Metabolome Database):HMDB03339
FooDB:FDB023148
Export Tariff Code:2922.42.5000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
(R)-2-amino-pentanedioic acid
(R)-2-aminoglutaric acid
(2R)-2-aminopentanedioic acid
(R)-2-aminopentanedioic acid
(R)-(-)-glutamic acid
D-glutamic acid
D-(-)-glutamic acid
D(-)-glutamic acid
 glutamic acid D-form
 glutamic acid, D-
 

Articles:

PubMed:IgE binding to peanut allergens is inhibited by combined d-aspartic and d-glutamic acids.
PubMed:Improved production of poly-γ-glutamic acid by Bacillus subtilis D7 isolated from Doenjang, a Korean traditional fermented food, and its antioxidant activity.
PubMed:Recombinant expression, purification and characterisation of the native glutamate racemase from Lactobacillus plantarum NC8.
PubMed:Alterations in D-amino acid concentrations and microbial community structures during the fermentation of red and white wines.
PubMed:Odor detection thresholds and enantiomeric distributions of several 4-alkyl substituted gamma-lactones in Australian red wine.
PubMed:Microstructure of poly(gamma-glutamic acid) produced by Bacillus subtilis consisting of clusters of D- and L-glutamic acid repeating units.
PubMed:The influence of manufacture on the free D-amino acid content of Cheddar cheese.
PubMed:D-amino acid formation in sterilized alkali-treated olives.
PubMed:Characterization of Bacillus cereus isolates associated with fatal pneumonias: strains are closely related to Bacillus anthracis and harbor B. anthracis virulence genes.
PubMed:Identification of anthrax toxin genes in a Bacillus cereus associated with an illness resembling inhalation anthrax.
PubMed:Anthrax toxin.
PubMed:Chemical analysis of poly-gamma-glutamic acid produced by plasmid-free Bacillus subtilis (natto): Evidence that plasmids are not involved in poly-gamma-glutamic acid production.
PubMed:A novel type of meso-diaminopimelic acid-based peptidoglycan and novel poly(erythritol phosphate) teichoic acids in cell walls of two coryneform isolates from the surface flora of French cooked cheeses.
PubMed:Evaluation of serologic tests for diagnosis of anthrax after an outbreak of cutaneous anthrax in Paraguay.
 
Notes:
There are two forms of glutamic acid found in nature: L-glutamic acid and D-glutamic acid. D-glutamic acid, is not endogenously produced in higher mammals. It is found naturally primarily in the cell walls of certain bacteria. D-glutamate is also present in certain foods e.g., soybeans and also arises from the turnover of the intestinal tract microflora, whose cell walls contain significant D-glutamate. Unlike other D-amino acids, D-glutamate is not oxidized by the D-amino acid oxidases, and therefore this detoxification pathway is not available for handling D-glutamate. Likewise, D-glutamic acid, when ingested, largely escapes most deamination reactions (unlike the L-counterpart). Free D-glutamate is found in mammalian tissue at surprisingly high levels, with D-glutamate accounting for 9% of the total glutamate present in liver. D-glutamate is the most potent natural inhibitor of glutathione synthesis identified to date and this may account for its localization to the liver, since circulating D-glutamate may alter redox stabiity (PMID 11158923). Certain eels are known to use D-glutamic acid as a phermone for chemical communication. [HMDB]
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