|
Category:antioxidants and preservatives for fragrance and flavor
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | pale yellow to red clear liquid (est) |
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 2.00 to 3.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 482.00 to 485.00 °C. @ 760.00 mm Hg
|
| Flash Point: | 410.00 °F. TCC ( 210.00 °C. )
|
| logP (o/w): | 10.962 (est) |
| Shelf Life: | 12.00 month(s) or longer if stored properly. |
| Storage: | refrigerate in tightly sealed containers. |
| Soluble in: |
| | alcohol | | | water, 2.978e-007 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
| ADM |
| NOVATOL 1490
|
| ADM |
| NOVATOL 5-67 NON GMO
|
| ADM |
| NOVATOL 5-67
Flavor: characteristic NOVATOL 5-67 is a clear, amber color, viscous oil having a slight characteristic vegetable oil aroma and a mild taste. NOVATOL 5-67 may oxidize upon exposure to air and light, resulting in gradual darkening. Nitrogen blanketing and protection from light, from heat, from transition metals and from alkalis are recommended. NOVATOL 5-67 is a concentrated form of natural source d-alpha-tocopherol derived from edible vegetable oils. Research indicates that the human body prefers the natural source Vitamin E, such as NOVATOL 5-67, over the synthetic forms. Moreover, based on the Food and Nutrition Board Expert Panel report on Vitamin E, d-alpha-tocopherol has twice the activity of synthetic forms, which means that natural Vitamin E is 100% more effective. (Dietary Reference Intakes For Vitamin C, Vitamin E, Selenium, and Carotenoids. 2000. Vitamin E , National Academy Press, Washington, D.C.,186-283.) NOVATOL 5-67 is an essential nutrient and dietary supplement widely used in softgel capsules and liquid preparations. |
| ADM |
| NOVATOL 5-87
Flavor: characteristic NOVATOL 5-87 is a clear, amber color, viscous oil having a slight characteristic vegetable oil aroma and a mild taste. NOVATOL 5-87 may oxidize upon exposure to air and light, resulting in gradual darkening. Nitrogen blanketing and protection from light, from heat, from transition metals and from alkalis are recommended. NOVATOL 5-87 is a concentrated form of natural source d-alpha-tocopherol derived from edible vegetable oils. Research indicates that the human body prefers the natural source Vitamin E, such as NOVATOL 5-87, over the synthetic forms. Moreover, based on the Food and Nutrition Board Expert Panel report on Vitamin E, d-alpha-tocopherol has twice the activity of synthetic forms, which means that natural Vitamin E is 100% more effective. (Dietary Reference Intakes For Vitamin C, Vitamin E, Selenium, and Carotenoids.2000. Vitamin E, National Academy Press, Washington, D.C., 186-283.) NOVATOL 5-87 is an essential nutrient and dietary supplement widely used in softgel capsules and liquid preparations. |
| ADM |
| NOVATOL HPMC
Flavor: characteristic NOVATOL HPMC has little to no taste or odor and is a white to off-white crystalline powder. d-Alpha-Tocopherol is the form of tocopherol that is better retained in human tissues. It is the only form of alpha-tocopherol found in nature. The low viscosity and high concentration make d-alpha tocopherol ideal for soft gel capsules. |
| ADM |
| NOVATOL REGULAR GRADE
Flavor: characteristic NOVATOL REGULAR GRADE has little to no taste or odor and is a white to off-white crystalline powder. d-Alpha-Tocopherol is the form of tocopherol that is better retained in human tissues. It is the only form of alpha-tocopherol found in nature. The low viscosity and high concentration make d-alpha tocopherol ideal for soft gel capsules. |
| Alfa Biotechnology |
| For experimental / research use only. |
| Vitamin E 98%
|
| Ambles Nature et Chimie |
| ALPHA TOCOPHEROL NAT
|
| American International Chemical, LLC. |
| Natural Vitamin E Alcohol 1000IU Light USP
|
| BOC Sciences |
| For experimental / research use only. |
| a-Tocophenol
|
| Jiangyin Healthway |
| Natural Vitamin E
|
| New functional food ingredients |
| OQEMA |
| Vitamin E
|
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| (+)-a-Tocopherol from vegetable oil, Type V, ∼1000 IU/g
|
| Sinoway Industrial |
| For experimental / research use only. |
| Natural vitamin E
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | None - None found. |
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | antioxidants and preservatives for fragrance and flavor |
| Recommendation for alpha-tocophenol usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for alpha-tocophenol flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
European Food Safety Authority (EFSA) reference(s):
|
Inability to assess the safety of beta-, gamma- and delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl-tocotrienol added for nutritional purposes as sources of beta-, gamma- and delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl- tocotrienol in food supplements and the bioavailability of beta-, gamma-, delta- tocopherol and alpha-, beta-, gamma-, delta- and desmethyl-tocotrienol from the different sources, based on the supporting dossiers [1]
View page or View pdf
|
Opinion on mixed tocopherols, tocotrienol tocopherol and tocotrienols as sources for vitamin E added as a nutritional substance in food supplements[1] - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing aids and Materials in Contact with food (AFC)
View page or View pdf
|
Scientific Opinion on the safety and efficacy of tocopherol-rich extracts of natural origin, tocopherol-rich extracts of natural origin/delta rich, synthetic tocopherol for all animal species
View page or View pdf
|
Scientific Opinion on the safety and efficacy of synthetic alpha-tocopherol for all animal species
View page or View pdf
|
Outcome of a public consultation on the Draft Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on Dietary Reference Values for vitamin E as a-tocopherol
View page or View pdf
|
Scientific Opinion on Dietary Reference Values for vitamin E as a-tocopherol
View page or View pdf
|
Scientific Opinion on the re-evaluation of tocopherol-rich extract (E 306), a-tocopherol (E 307), ?-tocopherol (E 308) and d-tocopherol (E 309) as food additives
View page or View pdf
|
| EPI System: View |
| ClinicalTrials.gov:search |
| Daily Med:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):59-02-9 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :6033 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:1 |
| (2S)-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]chroman-6-ol |
| Chemidplus:0000059029 |
| RTECS:DJ2900000 for cas# 59-02-9 |
References:
| | (2S)-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]chroman-6-ol |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 59-02-9 |
| Pubchem (cid): | 6033 |
| Pubchem (sid): | 134972125 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | almefrol | | | aquasol E | | 2H-1- | benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-, (2S)- | | | denamone | | 3,4- | dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol | | | emipherol | | | endo E | | | etamican | | | evitaminum | | | phytogermine | | | profecundin | | | syntopherol | | (S)-2,5,7,8- | tetramethyl-2-((4R,8S)-4,8,12-trimethyl-tridecyl)-chroman-6-ol | | (2S)-2,5,7,8- | tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol | | (2S)-2,5,7,8- | tetramethyl-2-[(4R,8S)-4,8,12-trimethyltridecyl]chroman-6-ol | | (+)-a- | tocopherol | | (+)-alpha- | tocopherol | | D-a- | tocopherol | | D-alpha | tocopherol | | D-alpha- | tocopherol | | dextro-alpha | tocopherol | | | tokopharm | | | vascuals | | natural | vitamin E | | natural | vitamin E alcohol 1000iu light USP | | natural | vitamin E alcohol 1000iu USP | | | vitamin E alpha | | | vitaplex E |
Articles:
|
3D/inchi