benzocaine
4-aminobenzoic acid ethyl ester

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  American International Chemical, Inc.

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  BZCWCM Benzocaine
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  94-09-7 Benzocaine >98%
  Benzocaine is a local anesthetic commonly used as a topical pain reliever or in cough drops

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  GP2011 Benzocaine

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  02-11000 BENZOCAINE NON-MICRONIZED USP
  02-11010 BENZOCAINE USP/BP GRADE
  02-11002 BENZOCAINE MICORNIZED USP

Name: ethyl 4-aminobenzoate CAS Number: 94-09-7 3D/inchi Other(deleted CASRN): 71123-91-6 ECHA EINECS - REACH Pre-Reg: 202-303-5 FDA UNII: U3RSY48JW5 Nikkaji Web: J4.690F Beilstein Number: 0638434 XlogP3: 1.90 (est) Molecular Weight: 165.19207000 Formula: C9 H11 N O2 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:pharmaceuticals / chemical synthisis   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Appearance: white crystalline powder (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Melting Point: 92.00 °C. @ 760.00 mm Hg Boiling Point: 310.00 °C. @ 760.00 mm Hg Vapor Pressure: 0.001000 mmHg @ 25.00 °C. (est) Flash Point: 328.00 °F. TCC ( 164.20 °C. ) (est) logP (o/w): 1.860 Soluble in:   water, 1310mg/L @ 30 °C (exp)   water, 1671 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: not used anymore   Suppliers: American International Chemical, LLC. Benzocaine USP American International Chemical, LLC. Benzocaine BOC Sciences For experimental / research use only. Benzocaine >98% Odor: characteristic Use: Benzocaine is a local anesthetic commonly used as a topical pain reliever or in cough drops Glentham Life Sciences Benzocaine Penta International BENZOCAINE MICORNIZED USP Penta International BENZOCAINE NON-MICRONIZED USP Penta International BENZOCAINE USP/BP GRADE Qingdao Dacon Trading Benzocaine Sigma-Aldrich For experimental / research use only. Ethyl 4-aminobenzoate 98%   Safety Information:   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-bird - wild LD50 56 mg/kg Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972. intraperitoneal-mouse LD50 216 mg/kg Journal of Medicinal Chemistry. Vol. 17, Pg. 900, 1974. oral-mouse LD50 2500 mg/kg BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS LUNGS, THORAX, OR RESPIRATION: DYSPNEA Toksikologicheskii Vestnik. Vol. (2), Pg. 34, 1996. oral-rabbit LDLo 1150 mg/kg Drugs in Japan Vol. 6, Pg. 33, 1982. oral-rat LD50 3042 mg/kg BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: CYANOSIS Toksikologicheskii Vestnik. Vol. (2), Pg. 34, 1996. Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: pharmaceuticals / chemical synthisis Recommendation for benzocaine usage levels up to:   not for fragrance use.   Recommendation for benzocaine flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search Daily Med:search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):94-09-7 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :2337 National Institute of Allergy and Infectious Diseases:Data WGK Germany:2 ethyl 4-aminobenzoate Chemidplus:0000094097 RTECS:DG2450000 for cas# 94-09-7   References:   ethyl 4-aminobenzoate NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 94-09-7 Pubchem (cid): 2337 Pubchem (sid): 134970801   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View KEGG (GenomeNet): D00552 HMDB (The Human Metabolome Database): HMDB04992 FooDB: FDB023574 Export Tariff Code: 2922.49.1500 ChemSpider: View Wikipedia: View Formulations/Preparations: •oral: lozenges 5 mg vicks chloraseptic children's sore throat lozenges, (procter & gamble); 10 mg cepacol anesthetic lozenges (with cetylpyridinium chloride), (williams jb), s[ec-tthroat lozenges, (bristol-myers); 15 mg mycinettes, (pfeiffer). •otic: solution: 20% americaine-otic (with benzethonium chloride), (celltech), otocain, (abana). •topical: aerosol: 20% hurricaine spray (with or without disposable extension tube), (beutlich). gel: 6.3% anbesol regular strength (with alcohol 70% and phenol), (wyeth); 7.5% anbesol baby, (wyeth), orabase baby (alcohol free), (colgate), orajel baby regular, (del); 10% orajel baby nighttime, (del), orajel regular strength, (del), orajel denture (with eugenol and propylene glycol), (del), zilactin-b medicated gel with benzocaine, (zila); 15% orabase gel (with alcohol), (colgate); 20% americaine anesthetic lubricant (with benzethonium chloride), (celltech), anbesol maximum strength (with alcohol 60%), (wyeth), hurricaine, (beutlich), orajel maximum strength, (del), orajel mouth-aid (with benzalkonium chloride povidone propylene glycol and zinc chloride), (del). paste: 20% orabase-b with benzocaine, (colgate-hoyt). solution: 2.5% babee teething lotion (with alcohol 20% cetalkonium chloride and propylene glycol), (pfeiffer), 6.3% anbesol regular strength (with alcohol 70% phenol and povidone-iodine yielding 0.04% iodine), (wyeth); 20% anbesol maximum strength (with alcohol 60%), (wyeth), hurricaine, (beutich), kank-a (with alcohol 0.5% aspartame benzyl alcohol and propylene glycol), (blistex), orajel mouth-aid liquid (with alcohol 70% cetylpyridinium chloride povidone and tartrazine), (del). •topical: aerosol 5% foille medicated first aid (with benzyl alcohol and chloroxylenol 0.1%), (blistex); 20% dermoplast (with menthol 0.5% and methylparaben), (medtech), solarcaine (with isopropyl alcohol 35% ww and triclosan 0.13%), (schering-plough). cream: 1% solarcaine (with trilosan 0.2%), (schering-plough); 5% benzocaine cream, (cmc, rugby), benzocol, (hauck), ivarest (with calamine 14% and propylene glycol), (blistex), rhulicream (with calamine 3% and camphor 0.3%), (rhydelle); 6% bicozene (with resorcinol 1.67%), (novartis). gel: 20% americaine anesthetic lubricant, (celltech), detane, (del). lotion: 0.5% solarcaine (with triclosan 0.2%), (schering-plough); 5% ivarest (with calamine 14% and propylene glycol), (blistex). ointment: 2% chiggerex, (scherer), 5% foille medicated first aid (with chloroxylenol 0.1%), (blistex); 10% anacaine (with boric acid), (gordon). solution: 2.1% chiggertox (with benzyl benzoate 21.4%), (scherer); 20% outgro, (medtech). •trade names: anaesthesin (ritsert, germany); hurricaine (beutlich, usa)   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms:   amercaine 4- amino-benzoic acid ethyl ester 4- aminobenzoic acid ethyl ester p- aminobenzoic acid, ethyl ester p- aminobenzoic ethyl ester p- aminophenylacetic acid ethyl ester   benzocaina   benzocaine non-micronized USP   benzocaine USP   benzocaine USP EP   benzocaine USP EP micronized   benzocaine USP micronized   benzocaine USP/BP grade   benzocainum   benzoic acid, 4-amino-, ethyl ester   cetacaine   ethyl 4-aminobenzoate   ethyl p-aminobenzoate   ethyl para-aminobenzoate   orthesin   Articles: PubMed:Encapsulation altered starch digestion: toward developing starch-based delivery systems.

Notes: a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.; Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. Benzocaine is an ester, a compound made from the organic acid PABA (para-aminobenzoic acid) and ethanol. The process in which this ester is created is known as Fischer esterification. [HMDB]