Category:antioxidants and preservatives for fragrance and flavor
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless clear liquid (est) |
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | Yes |
Specific Gravity: | 1.00500 to 1.01100 @ 25.00 °C.
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Pounds per Gallon - (est).: | 8.363 to 8.413
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Refractive Index: | 1.43000 to 1.43600 @ 20.00 °C.
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Boiling Point: | 188.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 0.600000 mmHg @ 30.00 °C. |
Flash Point: | > 300.00 °F. TCC ( > 148.89 °C. )
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logP (o/w): | -0.180 (est) |
Shelf Life: | 12.00 month(s) or longer if stored properly. |
Storage: | store under nitrogen. |
Storage: | refrigerate in tightly sealed containers. store under nitrogen. |
Soluble in: |
| alcohol | | water, 1.672e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
Odor Description:at 50.00 % in water. pungent fruity medicinal |
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | T N - Toxic, Dangerous for the environment. |
R 23/25 - Toxic by inhalation and if swallowed. R 34 - Causes burns. R 42/43 - May cause sensitization by inhalation and skin contact. R 50 - Very toxic to aquatic organisms. S 02 - Keep out of the reach of children. S 20/21 - When using do not eat, drink or smoke. S 23 - Do not breath fumes. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection. S 45 - In case of accident or if you feel unwell seek medical advice immediately. S 61 - Avoid release to the environment. Refer to special instructions/safety data sheet.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
gavage-rat LD50 252 mg/kg (Stonehill et al., 1963)
gavage-rat LD50 [sex: M] 733 mg/kg (Ballantyne & Myers, 2001)
gavage-rat LD50 [sex: M] 2380 mg/kg (Smyth et al., 1962)
gavage-rat LD50 [sex: M] 540 mg/kg (Striegel & Carpenter, 1964)
oral-rat LD50 [sex: M] 134 mg/kg (Ikeda, 1980)
oral-rat LD50 [sex: F] 165 mg/kg (Ikeda, 1980)
gavage-rat LD50 [sex: M] 1300 mg/kg (Myers et al., 1977b)
gavage-rat LD50 [sex: M] 1870 mg/kg (Myers et al., 1977c)
gavage-mouse LD50 352 mg/kg (Stonehill et al., 1963)
oral-mouse LD50 [sex: M] 100 mg/kg (Ikeda, 1980)
oral-mouse LD50 [sex: F] 110 mg/kg (Ikeda, 1980)
gavage-mouse LD50 [sex: M] 152 mg/kg (Ballantyne & Myers, 2001)
gavage-mouse LD50 [sex: F] 113 mg/kg (Ballantyne & Myers, 2001)
gavage-mouse LD50 [sex: M] 151 mg/kg (Union Carbide Corp., 1992)
gavage-mouse LD50 [sex: F] 115 mg/kg (Union Carbide Corp., 1992)
oral-guinea pig LD50 50 mg/kg (Union Carbide Corp., 1992)
oral-duck LD50 820 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: FOOD INTAKE (ANIMAL) National Technical Information Service. Vol. OTS0526410-1
oral-guinea pig LD50 50 mg/kg BEHAVIORAL: EXCITEMENT
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 52(3), Pg. 77, 1987.
intraperitoneal-mouse LD50 13900 ug/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 232, 1979.
intravenous-mouse LD50 15400 ug/kg Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 503, 1980.
oral-mouse LD50 100 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 503, 1980.
intraperitoneal-rat LD50 17900 ug/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 10, Pg. 232, 1979.
intravenous-rat LD50 9800 ug/kg United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1290-1008
oral-rat LD50 134 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 503, 1980.
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Dermal Toxicity: |
skin-rabbit LD50 560 ul/kg Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 503, 1980.
subcutaneous-rat LD50 > 750 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 503, 1980.
skin-rat LD50 > 2500 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 503, 1980.
skin-mouse LD50 > 5840 mg/kg Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 503, 1980.
skin-mouse LD50 > 5840 mg/kg SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 11, 1976.
subcutaneous-mouse LD50 > 590 mg/kg Drugs in Japan Vol. -, Pg. 395, 1995.
skin-rabbit LD50 560 uL/kg Union Carbide Data Sheet. Vol. 11/4/1971
skin-rat LD50 > 2500 mg/kg SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 11, 1976.
subcutaneous-rat LD50 > 750 mg/kg Drugs in Japan Vol. -, Pg. 395, 1995.
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Inhalation Toxicity: |
inhalation-rat LC50 480 mg/m3/4H Drugs in Japan Vol. -, Pg. 395, 1995.
inhalation-rat LC50 480 mg/m3/4H United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1290-1008
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Safety in Use Information:
Category: | antioxidants and preservatives for fragrance and flavor |
Recommendation for glutaric dialdehyde 50% in water usage levels up to: | | not for fragrance use.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.055 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | I (μg/capita/day) |
Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 1600 (μg/person/day) |
Threshold of Concern: | 1800 (μg/person/day) |
Structure Class: | I |
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Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). |
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. |
| average usage mg/kg | maximum usage mg/kg |
Dairy products, excluding products of category 02.0 (01.0): | 3.00000 | 15.00000 |
Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 2.00000 | 10.00000 |
Edible ices, including sherbet and sorbet (03.0): | 3.00000 | 15.00000 |
Processed fruit (04.1): | 2.00000 | 10.00000 |
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - |
Confectionery (05.0): | 4.00000 | 20.00000 |
Chewing gum (05.3): | - | - |
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 2.00000 | 10.00000 |
Bakery wares (07.0): | 5.00000 | 25.00000 |
Meat and meat products, including poultry and game (08.0): | 1.00000 | 5.00000 |
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 1.00000 | 5.00000 |
Eggs and egg products (10.0): | - | - |
Sweeteners, including honey (11.0): | - | - |
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 2.00000 | 10.00000 |
Foodstuffs intended for particular nutritional uses (13.0): | 3.00000 | 15.00000 |
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 2.00000 | 10.00000 |
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 4.00000 | 20.00000 |
Ready-to-eat savouries (15.0): | 5.00000 | 25.00000 |
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 2.00000 | 10.00000 |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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European Food Safety Authority (EFSA) reference(s):
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Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf
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Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf
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Flavouring Group Evaluation 64 (FGE.64): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated by EFSA in FGE.10Rev1 (EFSA, 2008ab) View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 92 (FGE.92): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (68th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones evaluated by EFSA in FGE.10Rev1 (2009) View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 10, Revision 3 (FGE.10Rev3): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 View page or View pdf
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EPI System: View |
NIOSH International Chemical Safety Cards:search |
NIOSH Pocket Guide:search |
Chemical Carcinogenesis Research Information System:Search |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
Carcinogenic Potency Database:Search |
EPA GENetic TOXicology:Search |
EPA Substance Registry Services (TSCA):111-30-8 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :3485 |
National Institute of Allergy and Infectious Diseases:Data |
WGK Germany:3 |
pentanedial |
Chemidplus:0000111308 |
EPA/NOAA CAMEO:hazardous materials |
RTECS:111-30-8 |
References:
Other Information:
(IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
Videos: | The Periodic Table of Videos |
tgsc: | Atomic Weights use for this web site |
(IUPAC): | Periodic Table of the Elements |
FDA Substances Added to Food (formerly EAFUS): | View |
FDA Indirect Additives used in Food Contact Substances: | View |
CHEBI: | View |
CHEMBL: | View |
KEGG (GenomeNet): | C12518 |
HMDB (The Human Metabolome Database): | HMDB29599 |
FooDB: | FDB000763 |
Export Tariff Code: | 2912.19.5000 |
FDA Listing of Food Additive Status: | View |
Wikipedia: | View |
Formulations/Preparations: •usepaopp pesticide code 043901; trade names: cidex, component of; odix, component of; aldesan; alhydex; glutaralum; hospex; nci-c55425; sonacide; coldcide-25 microbiocide concentrate; gkn-o microbiocide concentrate (043901+069104+069154).
•soluble concentrates, ready-to-use solutions, impregnated materials, water soluble packages, and microencapsulated preparations (medical waste). glutaraldehyde is not available as a neat, undiluted chemical. however, it is commercially available as 4%, 15%, 25%, 45%, and 50% (vv) aqueous solutions.
•it has been marketed as 2% alkaline soln in 70% isopropanol...
•cidex (arbrook) topical: soln (aq) 2%.
•grades: 99%; 50% biological solution; 25% solution.
•employed as 25% soln in water for embalming fluid.
•2% aq soln buffered with 0.3% sodium carbonate to ph of 7.5-8.5 is useful for disinfection and sterilization of endoscopic instruments & plastic & rubber apparatus used for inhalation therapy & anesthesia.
•usually sold commercially as a 45% or 50% aqueous solution.
•electron microscopy grade is highly purified
•biocide; supplied in acid solution and subsequently buffered to ph 8
•a-215 (ecolab) glutaral 15%
•a-245 (ecolab) glutaral 45%
•ama-1500g (kemira chemicals) glutaral 15%
•ama-2500g (kemira chemicals) glutaral 25%
•ama-5000g (kemira chemicals) glutaral 50%
•aqucar ga 23 sb water treatment microbicide (dow chemical) glutaral 23%
•aqucar ga 30lt water treatment microbicide (dow chemical) glutaral 30%
•aqucar 504 water treatment microbicide (dow chemical) glutaral 4%
•bactron k-31 microbicide (champion technologies) glutaral 25%
•bactron k-86 microbicide (champion technologies) glutaral 43.3%, alkyl dimethyl benzyl ammonium chloride 3.5%, alkyl dimethyl ethylbenzyl ammonium chloride 3.5%
•busan 1202 (buckman laboratories) glutaral 50%
•coldcide 0.25% (colcide) glutaral 0.275%, 4-ter-amylphenol 0.0027%, o-phenylphenol 0.0137%
•diald 15 (buckman laboratories) glutaral 15%
•diald 25 (buckman laboratories) glutaral 25%
•diald 45 (buckman laboratories) glutaral 45%
•diald 50 (buckman laboratories) glutaral 50%
•gkn-o (champion technologies) glutaral 25.75%, alkyl dimethyl benzyl ammonium chloride 6.25%, alkyl dimethyl ethylbenzyl ammonium chloride 6.25%
•glutex gq1 sanitizer and disinfectant (dow chemical) glutaral 14%, alkyl dimethyl benzyl ammonium chloride 2.5%
•maquat 25:12 (mason chemical) glutaral 25.7 %, alkyl dimethyl benzyl ammonium chloride 5%, alkyl dimethyl benzyl ammonium chloride 7.5%
•myacide ga 15 (basf) glutaral 15%
•myacide ga 25 (basf) glutaral 25%
•myacide ga 45 (basf) glutaral 45%
•myacide ga 50 (basf) glutaral 50%
•myacide gda technical (basf) glutaral 50%
•n-5033 antimicrobial (verichem) glutaral 50%
•owt-908 microbicide (nch) glutaral 25.75%, alkyl dimethyl ethylbenzyl ammonium chloride 6.25%, n-alkyl dimethyl benzyl ammonium chlorides 6.25%
•piror 842 slimicide (dow chemical) glutaral 42.5%, alkyl dimethyl benzyl ammonium chloride 7.5%
•premicide (metrex research) glutaral 9.61%
•sanisorbx (multisorb technologies) glutaral 9.6%
•spectrus nx1105 (ge betz) glutaral 45%
•sporicidin-hd concentrated for hemodialysis (contec) glutaral 13%, phenol 7.05%, sodium phenate 1.2%
•ster-cid (mcm environmental technologies) glutaral 10.72%, alkyl dimethyl benzyl ammonium chloride 17.06%, didecyl dimethyl ammonium chloride 7.8%
•surcide g-50 (surety laboratories) glutaral 50%
•ucarsan sanitizer 4128 (dow chemical) 12.8%
•ucarsan sanitizer 420 (dow chemical) glutaral 20%
•ucarcide 25 (dow chemical) glutaral 25%
•ucarcide 15 antimicrobial (dow chemical) glutaral 15%
•ucarcide 42 antimicrobial (dow chemical) glutaral 42.5%, alkyl dimethyl benzyl ammonium chloride 7.5%
•ucarcide 45 antimicrobial (dow chemical) glutaral 45%
•ucarcide 225 antimicrobial (dow chemical) glutaral 25%
•ucarcide 250 antimicrobial (dow chemical) glutaral 50%
•virocid (cid lines n.v.) glutaral 10.725%, alkyl dimethyl benzyl ammonium chloride 17.06%, didecyl dimethyl ammonium chloride 7.8%
•wavicide-06 plus (medical chemical corp) ethyl alcohol 50%, glutaral 0.25%
•x-cide 102 industrial bactericide (baker petrolite corp) glutaral 25%
•x-cide 105 (baker petrolite corp) glutaral 50%
•x-cide 107 industrial bactericide (baker petrolite corp.) glutaral 20%
•glutarol 10% glutaraldehyde wv cutaneous solution (dermal laboratories limited, uk).
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Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| cidex | 1,3- | diformyl propane | 1,3- | diformylpropane | | glutaral | | glutaraldehyde | | glutaraldehyde aqueous solution, 25% | | pentane dial | 1,5- | pentane dial | 1,5- | pentane dione | | pentanedial | 1,5- | pentanedial | | sonacide |
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PubMed:Physicochemical modification of kafirin microparticles and their ability to bind bone morphogenetic protein-2 (BMP-2), for application as a biomaterial. |
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PubMed:Macroscopic and microscopic analysis of the tongue of the common opossum (Didelphis marsupialis). |
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PubMed:Improvement of water barrier property of paperboard by coating application with biodegradable polymers. |
PubMed:Development of an immunoassay for rapid screening of vardenafil and its potential analogues in herbal products based on a group specific monoclonal antibody. |
PubMed:A comparison of the efficacy of different disinfection methods in eliminating Salmonella contamination from turkey houses. |
PubMed:Alternative reaction mechanism for the cross-linking of gelatin with glutaraldehyde. |
PubMed:A proton NMR relaxation study of water dynamics in bovine serum albumin nanoparticles. |
PubMed:Production of fructooligosaccharides by beta-fructofuranosidases from Aspergillus oryzae KB. |
PubMed:Bactericidal activity of glutaraldehyde-like compounds from olive products. |
PubMed:A comparison of the efficacy of cleaning and disinfection methods in eliminating Salmonella spp. from commercial egg laying houses. |
PubMed:Efficacy of chemical treatments against murine norovirus, feline calicivirus, and MS2 bacteriophage. |
PubMed:Morphology, release characteristics, and antimicrobial effect of nisin-loaded electrospun gelatin fiber mat. |
PubMed:Wireless biosensor system for real-time cholesterol monitoring in fish "Nile tilapia". |
PubMed:Lactose nano-probe optimized using response surface methodology. |
PubMed:Physicochemical and bioactivity of cross-linked chitosan-PVA film for food packaging applications. |
PubMed:Cytotoxicity and genotoxicity of superporous hydrogel containing interpenetrating polymer networks. |
PubMed:Collagen-based dermal fillers: past, present, future. |
PubMed:Hg(II) removal from water by chitosan and chitosan derivatives: a review. |
PubMed:Multidetermination of four nitrofurans in animal feeds by a sensitive and simple enzyme-linked immunosorbent assay. |
PubMed:Immobilization of recombinant thermostable beta-galactosidase from Bacillus stearothermophilus for lactose hydrolysis in milk. |
PubMed:Simultaneous detection of multifood-borne pathogenic bacteria based on functionalized quantum dots coupled with immunomagnetic separation in food samples. |
PubMed:Biofilm development capacity of Salmonella strains isolated in poultry risk factors and their resistance against disinfectants. |
PubMed:Stabilization of beta-galactosidase (from peas) by immobilization onto amberlite MB-150 beads and its application in lactose hydrolysis. |
PubMed:Warts (non-genital). |
PubMed:Juvéderm injectable gel: a multicenter, double-blind, randomized study of safety and effectiveness. |
PubMed:Neutrase immobilization on alginate-glutaraldehyde beads by covalent attachment. |
PubMed:Direct determination of sulfite in food samples by a biosensor based on plant tissue homogenate. |
PubMed:Performance enhancement of polyaniline-based polymeric wire biosensor. |
PubMed:Release properties of chemical and enzymatic crosslinked gelatin-gum Arabic microparticles containing a fluorescent probe plus vetiver essential oil. |
PubMed:Tests for genotoxicity and mutagenicity of furan and its metabolite cis-2-butene-1,4-dial in L5178Y tk+/- mouse lymphoma cells. |
PubMed:Determination of florfenicol amine residues in animal edible tissues by an indirect competitive ELISA. |
PubMed:Use of glutaraldehyde and benzalkonium chloride for minimizing post-harvest physio-chemical and microbial changes responsible for sucrose losses in sugar cane. |
PubMed:Chemistry and physical properties of melt-processed and solution-cross-linked corn zein. |
PubMed:Characterization of amino cross-linked soy protein hydrogels. |
PubMed:Immobilization of polygalacturonase from Aspergillus niger onto activated polyethylene and its application in apple juice clarification. |
PubMed:Simultaneous determination of sulphamerazine, sulphamethazine and sulphadiazine in honey and chicken muscle by a new monoclonal antibody-based fluorescence polarisation immunoassay. |
PubMed:Hemostats, sealants, and adhesives: components of the surgical toolbox. |
PubMed:Supramolecular structure of the casein micelle. |
PubMed:Modeling the inactivation kinetics of bacillus spores by glutaraldehyde. |
PubMed:Rapid enzyme-linked immunosorbent assay and colloidal gold immunoassay for kanamycin and tobramycin in Swine tissues. |
PubMed:[Study on isoflavone active aglycone preparation by immobilized beta-glucosidase from Aspergillus niger]. |
PubMed:Mechanism of infection of a human isolate Salmonella (3,10:r:-) in chicken ileum: ultrastructural study. |
PubMed:Extraction and electrospinning of gelatin from fish skin. |
PubMed:Bienzyme amperometric biosensor using gold nanoparticle-modified electrodes for the determination of inulin in foods. |
PubMed:Optimization of cross-linking parameters during production of transglutaminase-hardened spherical multinuclear microcapsules by complex coacervation. |
PubMed:Two biosensors for phenolic compounds based on mushroom (Agaricus bisporus) homogenate: comparison in terms of some important parameters of the biosensors. |
PubMed:Covalent attachment of lactase to low-density polyethylene films. |
PubMed:Analytical characterisation of glutardialdehyde cross-linking products in gelatine-gum arabic complex coacervates. |
PubMed:Immobilized protein films for assessing surface proteolysis kinetics. |
PubMed:Comparative study of thermostability and ester synthesis ability of free and immobilized lipases on cross linked silica gel. |
PubMed:An interference free amperometric biosensor for the detection of biogenic amines in food products. |
PubMed:Use of insoluble yeast beta-glucan as a support for immobilization of Candida rugosa lipase. |
PubMed:Interference with the quorum sensing systems in a Vibrio harveyi strain alters the growth rate of gnotobiotically cultured rotifer Brachionus plicatilis. |
PubMed:AOAC method 966.04: preliminary evaluation of cooked meat medium with manganese sulfate for the cultivation of Clostridium sporogenes: precollaborative study. |
PubMed:Immunohistochemical profile of some neurotransmitters and neurotrophins in the seminiferous tubules of rats treated by lonidamine. |
PubMed:Optimization of covalent immobilization of pectinase on sodium alginate support. |
PubMed:Composite films from pectin and fish skin gelatin or soybean flour protein. |
PubMed:Construction of a dimethyl sulfoxide sensor based on dimethyl sulfoxide reductase immobilized on a au film electrode. |
PubMed:Warts (non-genital). |
PubMed:Enantioselective screen-printed amperometric biosensor for the determination of D-amino acids. |
PubMed:Electrochemical estimation of the polyphenol index in wines using a laccase biosensor. |
PubMed:Patient safety considerations regarding dermal filler injections. |
PubMed:Study of immobilized and extracellular saccharase of watermelon. |
PubMed:Impact of sodium chloride on Escherichia coli O157:H7 and Staphylococcus aureus analysed using transmission electron microscopy. |
PubMed:Spores of Bacillus subtilis: their resistance to and killing by radiation, heat and chemicals. |
PubMed:Development of cholesterol biosensor based on immobilized cholesterol esterase and cholesterol oxidase on oxygen electrode for the determination of total cholesterol in food samples. |
PubMed:Efficient biosynthesis of D-allose from D-psicose by cross-linked recombinant L-rhamnose isomerase: separation of product by ethanol crystallization. |
PubMed:Development of biosensor based on immobilized L-glutamate oxidase for determination of monosodium glutamate in food. |
PubMed:Microgravity effects on leaf morphology, cell structure, carbon metabolism and mRNA expression of dwarf wheat. |
PubMed:Physicochemical, antimicrobial, and cytotoxic characteristics of a chitosan film cross-linked by a naturally occurring cross-linking agent, aglycone geniposidic acid. |
PubMed:Construction and analysis of fractional multifactorial designs to study attachment strength and transfer of Listeria monocytogenes from pure or mixed biofilms after contact with a solid model food. |
PubMed:Tegress: a new approach to urethral implants. |
PubMed:Softening of cattle hoof soles and swelling of heel horn by environmental agents. |
PubMed:Interaction of live and dead Escherichia coli O157:H7 and fluorescent microspheres with lettuce tissue suggests bacterial processes do not mediate adherence. |
PubMed:A biosensor based on co-immobilized L-glutamate oxidase and L-glutamate dehydrogenase for analysis of monosodium glutamate in food. |
PubMed:Improved immobilization yields by addition of protecting agents in glutaraldehyde-induced immobilization of protease. |
PubMed:Development and characterization of films based on chemically cross-linked gliadins. |
PubMed:A biosensor based on catalase for determination of highly toxic chemical azide in fruit juices. |
PubMed:A fluorescent glucose biosensor based on immobilized glucose oxidase on bamboo inner shell membrane. |
PubMed:Evaluation of a capillary immunoassay system for detection of Salmonella typhimurium in poultry products. |
PubMed:Development of time-resolved chemiluminescence for the determination of antu in river water, wheat, barley, and oat grain samples. |
PubMed:Study of immobilized and extracellular aminopeptidases of watermelon. |
PubMed:Development of an amperometric hypoxanthine biosensor for determination of hypoxanthine in fish and meat tissue. |
PubMed:Conformation-dependent inactivation of human betaine-homocysteine S-methyltransferase by hydrogen peroxide in vitro. |
PubMed:Structural and functional characterization of glutaraldehyde-polymerized bovine hemoglobin and its isolated fractions. |
PubMed:Possible associations between Salmonella persistence in poultry houses and resistance to commonly used disinfectants and a putative role of mar. |
PubMed:Uncovering the first double brimmed hat-shaped ascospores in Ambrosiozyma platypodis Van der Walt. |
PubMed:Preparation and characterization of nanoparticles containing trypsin based on hydrophobically modified chitosan. |
PubMed:Surface disinfection tests with Salmonella and a putative indicator bacterium, mimicking worst-case scenarios in poultry houses. |
PubMed:Evaluation of a new biosensor-based mushroom (Agaricus bisporus) tissue homogenate: investigation of certain phenolic compounds and some inhibitor effects. |
PubMed:Production of low-lactose milk by means of nonisothermal bioreactors. |
PubMed:Inactivation of the coronavirus that induces severe acute respiratory syndrome, SARS-CoV. |
PubMed:Production of lipase in a fermentor using a mutant strain of Corynebacterium species: its partial purification and immobilization. |
PubMed:Impact of cleaning and disinfection agents on biofilm structure and on microbial transfer to a solid model food. |
PubMed:Fungal mycelium--the source of chitosan for chromatography. |
PubMed:Immobilization of catalase by entrapment of permeabilized yeast cells in hen egg white using glutaraldehyde. |
PubMed:Oligomerization is required for betaine-homocysteine S-methyltransferase function. |
PubMed:Chitosan microspheres as a potential carrier for drugs. |
PubMed:Freeze-substitution and low-temperature embedding of dairy products for transmission electron microscopy. |
PubMed:Continuous disinfection as a means to control infectious diseases in poultry. Evaluation of a continuous disinfection programme for broilers. |
PubMed:Generation of group-specific antibodies against sulfonamides. |
PubMed:Intrinsic and acquired resistance to quaternary ammonium compounds in food-related Pseudomonas spp. |
PubMed:Symmetric focal degeneration in the cerebellar and vestibular nuclei in swine caused by ingestion of Aeschynomene indica seeds. |
PubMed:[Preparation and identification of anti-fumonisin B1 monoclonal antibody]. |
PubMed:Efficacy of glutaraldehyde disinfectant against Cryptosporidium parvum in the presence of various organic soils. |
PubMed:Cytotoxicity of liquid disinfectants. |
PubMed:Encapsulation of chlorothiazide in whey proteins: effects of wall-to-core ratio and cross-linking conditions on microcapsule properties and drug release. |
PubMed:Immobilisation of cyclodextrin glucanotransferase from Bacillus circulans ATCC 21783 on purified seasand. |
PubMed:Effectiveness of commercial disinfectants for inactivating hepatitis A virus on agri-food surfaces. |
PubMed:Addition of fish oil to diets for dairy cows. II. Effects on milk fat and gene expression of mammary lipogenic enzymes. |
PubMed:Addition of protected and unprotected fish oil to diets for dairy cows. I. Effects on the yield, composition and taste of milk. |
PubMed:Reversible denaturation behavior of immobilized glucose oxidase. |
PubMed:Production of alginate microspheres by internal gelation using an emulsification method. |
PubMed:Study on a Horseradish Peroxidase Biosensor Based on N-methylene Phenazine as a Mediator. |
PubMed:Chronic toxicity and oncogenicity study with glutaraldehyde dosed in the drinking water of Fischer 344 rats. |
PubMed:Gliadin matrices for microencapsulation processes by simple coacervation method. |
PubMed:Enzyme sensor array for the determination of biogenic amines in food samples. |
PubMed:In vivo biocompatibility and degradability of a novel injectable-chitosan-based implant. |
PubMed:Chemical reactions in cottonseed protein cross-linking by formaldehyde, glutaraldehyde, and glyoxal for the formation of protein films with enhanced mechanical properties. |
PubMed:Generation of class-selective monoclonal antibodies against the penicillin group. |
PubMed:Minimizing hazardous exposures in the healthcare environment. |
PubMed:Effects of glutaraldehyde polymerization on oxygen transport and redox properties of bovine hemoglobin. |
PubMed:Simultaneous monitoring of glucose and lactate by an interference and cross-talk free dual electrode amperometric biosensor based on electropolymerized thin films. |
PubMed:Scanning electron-microscopic view of the oral and basal epithelial surfaces of the rat soft palate. |
PubMed:A rapid method for determining the tuberculocidal activity of liquid chemical germicides. |
PubMed:Delivery of injectable agents for treatment of stress urinary incontinence in women: evolving techniques. |
PubMed:The hydrophobic character of peanut (Arachis hypogaea) isoagglutinins. |
PubMed:Microencapsulation of theophylline in composite wall system consisting of whey proteins and lipids. |
PubMed:Efficacy of high-level disinfectants for reprocessing GI endoscopes in simulated-use testing. |
PubMed:A novel chitosan derivative to immobilize alpha-L-rhamnopyranosidase from Aspergillus niger for application in beverage technologies. |
PubMed:Development and application of an enzyme-linked immunosorbent assay for the analysis of hydrolyzed fumonisins. |
PubMed:Enzyme immobilization on nylon-optimization and the steps used to prevent enzyme leakage from the support. |
PubMed:Resistance of Pseudomonas aeruginosa to liquid disinfectants on contaminated surfaces before formation of biofilms. |
PubMed:Injectable agents in the treatment of stress urinary incontinence in women: where are we now? |
PubMed:Two-generation reproduction study by dosing with glutaraldehyde in the drinking water of CD rats. |
PubMed:Microencapsulation of theophylline in whey proteins: effects of core-to-wall ratio. |
PubMed:Development of a sensitive ELISA for the determination of fumonisin B(1) in cereals. |
PubMed:Evaluation of silica- and sepharose-based immunoaffinity sorbents for sample cleanup in determination of fumonisins B1 and B2 in corn products. |
PubMed:Stabilization of D-amino acid oxidase and catalase in permeabilized Rhodotorula gracilis cells and its application for the preparation of alpha-ketoacids*. |
PubMed:Recovery and sporicidal resistance of various B. subtilis spore preparations on porcelain penicylinders compared with results from AOAC test methods. |
PubMed:Preparation and some properties of water-insoluble, whey protein-based microcapsules. |
PubMed:Preparation and properties of glutaraldehyde cross-linked whey protein-based microcapsules containing theophylline. |
PubMed:GI endoscopic reprocessing practices in the United States. |
PubMed:Don't make a splash. |
PubMed:The efficacy of three common hospital liquid germicides to inactivate Cryptosporidium parvum oocysts. |
PubMed:The potential of monoclonal antibodies against ampicillin for the preparation of a multi-immunoaffinity chromatography for penicillins. |
PubMed:Injection therapy for stress incontinence in women. |
PubMed:In vitro evaluation of cytotoxicity of a naturally occurring cross-linking reagent for biological tissue fixation. |
PubMed:Sporicidal testing of commercial germicides using a chemical standard and a calibrated bioindicator. |
PubMed:Testing the potential of sodium fluoride to affect spermatogenesis: a morphometric study. |
PubMed:Study of the morphology of the cell walls of some strains of lactic acid bacteria and related species. |
PubMed:Effects of salt and serum on the sporicidal activity of liquid disinfectants. |
PubMed:Investigation with chitosan-oxalate oxidase-catalase conjugate for degrading oxalate from hyperoxaluric rat chyme. |
PubMed:Comparative sensitivity of 13 species of pathogenic bacteria to seven chemical germicides. |
PubMed:Continuous sucrose hydrolysis by yeast cells immobilized to wool. |
PubMed:A solvent-based fixative for electron microscopy to improve retention and visualization of the intestinal mucus blanket for probiotics studies. |
PubMed:Comparison of the properties of trypsin immobilized on 2 Celite derivatives. |
PubMed:Germ warfare! Infection control rules, regulations and guidelines. |
PubMed:Comparative sporicidal effect of liquid chemical germicides on three medical devices contaminated with spores of Bacillus subtilis. |
PubMed:Bovine pericardium for dural grafts: clinical results in 35 patients. |
PubMed:Reuse of disposable medical products. |
PubMed:Submucosal bladder neck injection of bovine dermal collagen for stress urinary incontinence in the pediatric population. |
PubMed:Glutaraldehyde. FDA holds firm on need for 45-minute soak. |
PubMed:Cupric and ferric ions inactivate HIV. |
PubMed:Comparative sporicidal effects of liquid chemical agents. |
PubMed:Glutaraldehyde retains its disinfectant properties in presence of hydroxypropylmethyl cellulose (HPMC) gel. |
PubMed:Comparative morphology and cytology of the olfactory organs in Moray eels with remarks on their foraging behavior. |
PubMed:Collagen injections for treatment of urinary incontinence secondary to intrinsic sphincter deficiency. |
PubMed:Development of a flow injection analysis (FIA) immunosensor for the detection of Escherichia coli. |
PubMed:New glutaraldehyde labeling controversial. |
PubMed:Glutaraldehyde sterilants: FDA vs. APIC soaking times. |
PubMed:Effects of intra- and intermolecular crosslinking on the free radical reactions of bovine hemoglobins. |
PubMed:Chalcone synthase localization in early stages of plant development. I. Immunohistochemical use of plasmolysis for localizing the enzyme in epidermal cell cytoplasm of illuminated buckwheat hypocotyls. |
PubMed:Detection of lectin activity on western blots using erythrocytes. |
PubMed:Convenience of immobilized Bacillus licheniformis alpha-amylase as time-temperature-integrator (TTI). |
PubMed:Virus inactivation by copper or iron ions alone and in the presence of peroxide. |
PubMed:Sporicidal activity of chemical sterilants used in hospitals. |
PubMed:Simultaneous kinetic-based determination of fructose and ascorbate with a rotating bioreactor and amperometric detection: application to the analysis of food samples. |
PubMed:Evaluation of 57 teat sanitizers using excised cow teats. |
PubMed:Production of polyclonal antibodies to the trichothecene mycotoxin 4,15-diacetylnivalenol with the carrier-adjuvant cholera toxin. |
PubMed:A simple technique for the immobilization of lysozyme by cross-linking of hen egg white foam. |
PubMed:Sporicidin update: are the government's regulatory teeth tearing a hole in industry? |
PubMed:Preliminary evaluation of a simple method for detection of bovine tuberculosis: the glutaraldehyde test. |
PubMed:Identification and enumeration of Listeria monocytogenes by nonradioactive DNA probe colony hybridization. |
PubMed:Improvement of the selectivity of an FIA amperometric biosensor system for glucose. |
PubMed:Intracellular digestion of human erythrocytes by Entamoeba histolytica: a kinetic study in vitro. |
PubMed:Teratological assessment of glutaraldehyde in rats by gastric intubation. |
PubMed:Metal-based formulations with high microbicidal activity. |
PubMed:Sporicidin responds to the recall of its products. |
PubMed:Thermostability of soluble and immobilized alpha-amylase from Bacillus licheniformis. |
PubMed:Processing flexible endoscopes: glutaraldehyde and the STERIS SYSTEM 1. |
PubMed:Immobilization of invertase through its carbohydrate moiety on Ocimum basilicum seed. |
PubMed:Pharmacokinetics of doxorubicin loaded and glutaraldehyde treated erythrocytes in healthy and lymphoma bearing dogs. |
PubMed:Porcine aortic valve bioprostheses: morphologic and functional considerations. |
PubMed:The Sporicidin recall. |
PubMed:Identification and characterization of cerebral-to-buccal interneurons implicated in the control of motor programs associated with feeding in Aplysia. |
PubMed:Factors associated with failure of passive transfer of colostral antibodies in Standardbred foals. |
PubMed:Amperometric determination of amino group on a solid support using glutaraldehyde. |
PubMed:Adaptations of the rat small intestine to a single and a double period of undernutrition. |
PubMed:A method for the preparation of coimmobilizates by adhesion using polyethylenimine. |
PubMed:Transport of exogenous fluorescent phosphatidylserine analogue to the Golgi apparatus in cultured fibroblasts. |
PubMed:Rapid and sensitive sandwich enzyme-linked immunosorbent assay for detection of staphylococcal enterotoxin B in cheese. |
PubMed:Endoscopic injection of glutaraldehyde cross-linked bovine dermal collagen for correction of vesicoureteral reflux. |
PubMed:Evaluation of titanium dental implant osseointegration in posterior edentulous areas of micro swine. |
PubMed:Striated brush border of intestinal absorptive epithelial cells: stereological studies on microvillous morphology in different adaptive states. |
PubMed:Immobilization of the serine protease from Thermomonospora fusca YX on porous glass. |
PubMed:Local tissue reaction to the subureteral injection of glutaraldehyde cross-linked bovine collagen in humans. |
PubMed:Porcine aortic valve bioprostheses: a morphologic comparison of the effects of fixation pressure. |
PubMed:Enzyme immobilization by the formation of enzyme coating on small pore-size ion-exchangers. |
PubMed:Hydrolysis of concentrated sucrose syrups by invertase immobilized on anion exchanger waste cotton thread. |
PubMed:Expression of pre-S2 region of hepatitis B surface antigen in Escherichia coli. |
PubMed:Comparison of four screening techniques for the diagnosis of equine neonatal hypogammaglobulinemia. |
PubMed:Forced-flow bioreactor for sucrose inversion using ceramic membrane activated by silanization. |
PubMed:Ten year experience with the negatively charged glutaraldehyde-tanned vascular graft in peripheral vascular surgery. Initial multicenter trial. |
PubMed:Characterization of erythropoietin receptor of murine erythroid cells. |
PubMed:Enzymatic enhancement of the catalytic rate of sulfhydryl oxidase. |
PubMed:Effects of a lengthy period of undernutrition from birth and subsequent nutritional rehabilitation on the synapse: granule cell neuron ratio in the rat dentate gyrus. |
PubMed:Decontamination of Campylobacter jejuni on chicken drumsticks using chemicals and radiation. |
PubMed:Response of the medullary thick ascending limb to hypothyroidism in the rat. |
PubMed:The effects of a 30 day period of environmental diversity on well-fed and previously undernourished rats: neuronal and synaptic measures in the visual cortex (area 17). |
PubMed:Perinatal age determines the severity of retarded lung development induced by starvation. |
PubMed:Preparative resolution of D,L-threonine catalyzed by immobilized phosphatase. |
PubMed:Hydrolysis of milk lactose by immobilized beta-galactosidase-hen egg white powder. |
PubMed:The effects of environmental diversity on well fed and previously undernourished rats: neuronal and glial cell measurements in the visual cortex (area 17). |
PubMed:Comparative evaluation of different enzyme-linked immunosorbent assay systems for the detection of staphylococcal enterotoxins A, B, C, and D. |
PubMed:Food deprivation and surfactant in adult rats. |
PubMed:Kidney structure in hypothyroidism. |
PubMed:Mutagenicity evaluation of glutaraldehyde in a battery of in vitro bacterial and mammalian test systems. |
PubMed:Ultrastructural evidence of long-lasting cerebellar degeneration after early exposure to phenobarbital in mice. |
PubMed:Comparison of extracellular space in the mature and aging rat brain using a new technique. |
PubMed:The effect of pH adjustment on the microbiology of chicken scald-tank water with particular reference to the death rate of salmonellas. |
PubMed:An analysis of discoidin I binding sites in Dictyostelium discoideum (NC4). |
PubMed:Lung morphometry in guinea pigs acclimated to cold during growth. |
PubMed:Food capture and ingestion in the large heliozoan, Echinosphaerium nucleofilum. |
PubMed:[Protein A research in 1200 strains of Staphylococcus (using a rapid detection technic by passive hemagglutination with glutaraldehyde treated erythrocytes]. |
PubMed:Pepsin immobilized on inorganic supports for the continuous coagulation of skim milk. |
PubMed:Immobilized enzymes on chitosan columns: alpha-chymotrypsin and acid phosphatase. |
PubMed:[The circadian structure of the parotid gland. morphologic and morphometric investigations (author's transl)]. |
PubMed:Reaction of glutaraldehyde with food-and-mouth disease virus. |
PubMed:Lactase and other enzymes bound to a phenol-formaldehyde resin with glutaraldehyde. |
PubMed:Effects of glutaraldehyde on the protein loss and photochemical properties of kale chloroplasts: preliminary studies on food conversion. |
PubMed:The influence of the mode of nutrition on the digestive system of Ochromonas malhamensis. |
PubMed:The feeding mechanism of avian malarial parasites. |
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one of the protein cross-linking reagents that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative. Used as an antimicrobial agent in sugar mills and as a fixing agent in the immobilisation of glucose isomerase enzyme preparations for use in the manuf. of high fructose corn syrup
A polymerized isomer of glutaraldehyde known as polycycloglutaracetal is a fertilizer for aquatic plants. It is claimed that it provides a bioavailable source of carbon for higher plants that is not available to algae. Though not marketed as such due to federal regulations, the biocidal effect of glutaraldehyde kills most algae at concentrations of 0.5 - 5.0 ppm. These levels are not harmful to most aquatic fauna and flora. Adverse reactions have been observed by some aquarists at these concentrations in some aquatic mosses, liverworts, and vascular plants.; Glutaraldehyde is a colorless liquid with a pungent odor used to disinfect medical and dental equipment. It is also used for industrial water treatment and as a chemical preservative.; Glutaraldehyde is an oily liquid at room temperature (density 1.06 g/mL), and miscible with water, alcohol, and benzene. It is used as a tissue fixative in electron microscopy. It is employed as an embalming fluid, is a component of leather tanning solutions, and occurs as an intermediate in the production of certain industrial chemicals. Glutaraldehyde is frequently used in biochemistry applications as an amine-reactive homobifunctional crosslinker. The oligomeric state of proteins can be examined through this application.; However, it is toxic, causing severe eye, nose, throat and lung irritation, along with headaches, drowsiness and dizziness. It is a main source of occupational asthma among health care providers.
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