EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

stannous chloride
dichlorostannane

Supplier Sponsors

CAS Number: 7772-99-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:231-868-0
FDA UNII: R30H55TN67
MDL:MFCD00011241
Molecular Weight:189.61400000
Formula:Cl2 Sn
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:antioxidants and preservatives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1845 Stannous Chloride View - review
JECFA Food Additive: Stannous Chloride
GSFA Codex: Stannous chloride (512)
DG SANTE Food Additives:stannous chloride
FDA Mainterm (SATF):7772-99-8 ; STANNOUS CHLORIDE
FDA Regulation:
FDA PART 155 -- CANNED VEGETABLES
Subpart B--Requirements for Specific Standardized Canned Vegetables
Sec. 155.200 Certain other canned vegetables.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart B--Food Preservatives
Sec. 172.180 Stannous chloride.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2600 Rubber articles intended for repeated use.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1845 Stannous chloride (anhydrous and dihydrated).
 
Physical Properties:
Appearance:white crystals (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 alcohol
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: reducing agents
 
Suppliers:
Allan Chemical
Stannous Chloride
BOC Sciences
For experimental / research use only.
Tin(II) chloride 95%
EMD Millipore
For experimental / research use only.
Tin(II) chloride
Kraft Chemical
Stannous Chloride
Santa Cruz Biotechnology
For experimental / research use only.
Tin(II) chloride ≥98%
Sigma-Aldrich
For experimental / research use only.
Tin(II) chloride anhydrous, powder, =99.99% trace metals basis
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 700 mg/kg
Food Research. Vol. 7, Pg. 313, 1942.

intravenous-rat LD50 17 mg/kg
United States Patent Document. Vol. #5015462

intraperitoneal-rat LD50 316 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.

oral-rabbit LD50 10000 mg/kg
FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 75, 1970.

oral-mouse LD50 250 mg/kg
FAO Nutrition Meetings Report Series. Vol. 50A, Pg. 101, 1972.

intravenous-mouse LD50 17.80 mg/kg
NIOSH Exchange Chemicals. Vol. NX#02202

intravenous-dog LDLo 20 mg/kg
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1420, 1935.

oral-dog LDLo 500 mg/kg
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1420, 1935.

oral-guinea pig LDLo 60 mg/kg
FAO Nutrition Meetings Report Series. Vol. 50A, Pg. 101, 1972.

unreported-mammal (species unspecified) LD50 215 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 55(12), Pg. 17, 1990.

intraperitoneal-mouse LD50 65598 ug/kg
Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.

intravenous-mouse LD50 17800 ug/kg
U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02202

Dermal Toxicity:
subcutaneous-dog LDLo 159 mg/kg
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.

subcutaneous-guinea pig LDLo 400 mg/kg
BEHAVIORAL: COMA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
British Medical Journal. Vol. 2, Pg. 217, 1913.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
antioxidants and preservatives
Recommendation for stannous chloride usage levels up to:
 not for fragrance use.
 
Recommendation for stannous chloride flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Re-evaluation of stannous chloride (E 512) as food additive
View page or View pdf

EPI System: View
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):7772-99-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24479
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
dichlorotin
Chemidplus:0007772998
EPA/NOAA CAMEO:hazardous materials
RTECS:7772-99-8
 
References:
 dichlorotin
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7772-99-8
Pubchem (cid):24479
Pubchem (sid):134990149
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
HMDB (The Human Metabolome Database):HMDB36545
FooDB:FDB015448
Export Tariff Code:2827.37.0000
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•stannous chloride is available in 2 forms: anhydrous and stannous chloride dihydrate, also called tin crystals or tin salts. •grades: technical; chemically pure; reagent. ... •anhydrous, 99.5% reagent and 99% technical grades. ...
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 reducing agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 dichlorostannane
 dichlorotin
 stannous chloride, anhydrous
 tin dichloride
 tin(II) chloride
 tin(II) chloride (1:2)
 

Articles:

Info:EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS
PubMed:Simultaneously determination of methyl and inorganic mercury in fish species by cold vapour generation atomic absorption spectrometry.
PubMed:Volatile generation in bell peppers during frozen storage and thawing using selected ion flow tube mass spectrometry (SIFT-MS).
PubMed:Using stannous ion as an excellent inorganic ECL coreactant for tris(2,2'-bipyridyl) ruthenium(II).
PubMed:Effect of enzymes on strawberry volatiles during storage, at different ripeness level, in different cultivars, and during eating.
PubMed:Effect of enzyme activity and frozen storage on jalapeƱo pepper volatiles by selected ion flow tube-mass spectrometry.
PubMed:Early life stage and genetic toxicity of stannous chloride on zebrafish embryos and adults: toxic effects of tin on zebrafish.
PubMed:Deacidification of high free fatty acid-containing rice bran oil by non-conventional reesterification process.
PubMed:Developmental and genetic toxicity of stannous chloride in mouse dams and fetuses.
PubMed:SnCl(2) reduces voltage-activated calcium channel currents of dorsal root ganglion neurons of rats.
PubMed:Determination of total mercury and methylmercury in biological samples by photochemical vapor generation.
PubMed:Stannous chloride induces alterations in enzyme activities, lipid peroxidation and histopathology in male rabbit: antioxidant role of vitamin C.
PubMed:Selenomethionine contents of NIST wheat reference materials.
PubMed:Comparative assessment of gastrointestinal irritant potency in man of tin(II) chloride and tin migrated from packaging.
PubMed:Evaluation of estrogenicity of major heavy metals.
PubMed:Effect of a chayotte (Sechium edule) extract on the labeling of red blood cells and plasma proteins with technetium-99m: in vitro and in vivo studies.
PubMed:Assessment of the effect of Fucus vesiculosus extract on the labeling of blood constituents with technetium-99m and the histological modifications on the shape of the red blood cells.
PubMed:Biological effects of stannous chloride, a substance that can produce stimulation or depression of the central nervous system.
PubMed:Genotoxic effects of stannous chloride (SnCl2) in K562 cell line.
PubMed:Effect of an extract of cauliflower (leaf) on the labeling of blood elements with technetium-99m and on the survival of Escherichia coli AB1157 submitted to the treatment with stannous chloride.
PubMed:Development and validation of hydroxy ethyl starch kits for instant use in gastroesophageal reflux and gastric motility studies.
PubMed:Effect of the Cymbopogon citratus, Maytenus ilicifolia and Baccharis genistelloides extracts against the stannous chloride oxidative damage in Escherichia coli.
PubMed:Selenomethionine content of candidate reference materials.
PubMed:An evaluation of analytical techniques for determination of lead, cadmium, chromium, and mercury in food-packaging materials.
PubMed:Damage induced by stannous chloride in plasmid DNA.
PubMed:Stannous chloride mediates single strand breaks in plasmid DNA through reactive oxygen species formation.
PubMed:Shark cartilage-containing preparation: protection against reactive oxygen species.
PubMed:Cellular inactivation induced by a radiopharmaceutical kit: role of stannous chloride.
PubMed:Estimation of toxicity of chemical mixtures through modeling of chemical interactions.
PubMed:Subacute toxicity of a mixture of nine chemicals in rats: detecting interactive effects with a fractionated two-level factorial design.
PubMed:Clinical efficacy of an optimized stannous fluoride dentifrice, Part 5: A 3-month study of extrinsic tooth staining, northeast USA.
PubMed:Headspace gas-liquid chromatographic determination of dithiocarbamate residues in fruits and vegetables with confirmation by conversion to ethylenethiourea.
PubMed:Lethality induced by stannous chloride on Escherichia coli AB1157: participation of reactive oxygen species.
PubMed:Evaluation of potential genotoxicity of stannous chloride: inactivation, filamentation and lysogenic induction of Escherichia coli.
PubMed:Speciation of inorganic and organotin compounds in biological samples by liquid chromatography with inductively coupled plasma mass spectrometric detection.
PubMed:4-week oral toxicity study of a combination of eight chemicals in rats: comparison with the toxicity of the individual compounds.
PubMed:[Toxic effects of tin. I. Inorganic tin compounds].
PubMed:Comparative toxicity of alkyltin and estertin stabilizers.
PubMed:Carcinogenesis Bioassay of Stannous Chloride (CAS No. 7772-99-8) in F344/N Rats and B6C3F1/N Mice (Feed Study).
PubMed:Effects of dietary tin on tin and calcium metabolism of adult males.
PubMed:[Nutritional and toxicological impacts of administered inorganic tin for six months in rats (author's transl)].
PubMed:Selenium in foods: evaluation of atomic absorption spectrometric techniques involving hydrogen selenide generation and carbon furnace atomization.
 
Notes:
Food additive (antioxidant) e.g. for colour retention in canned vegetables such as asparagus [DFC]
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