EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

forchlorfenuron

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CAS Number: 68157-60-8Picture of molecule3D/inchi
FDA UNII: K62IP7463J
Nikkaji Web:J236.162K
Beilstein Number:481338
XlogP3-AA:2.40 (est)
Molecular Weight:247.68390000
Formula:C12 H10 Cl N3 O
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 39 mg/L @ 21C (exp)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
4-CPPU
Odor: characteristic
Use: A plant growth regulator that increases fruit size; works synergistically with the plants auxin hormones to increase growth; is considered a dangerous good
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
herbicides / pesticides
Recommendation for forchlorfenuron usage levels up to:
 not for fragrance use.
 
Recommendation for forchlorfenuron flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Peer review of the pesticide risk assessment of the active substance forchlorfenuron
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :93379
National Institute of Allergy and Infectious Diseases:Data
1-(2-chloropyridin-4-yl)-3-phenylurea
Chemidplus:0068157608
 
References:
 1-(2-chloropyridin-4-yl)-3-phenylurea
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):93379
Pubchem (cas):68157-60-8
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C18604
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
1-(2-chloro-4-pyridinyl)-3-phenylurea
N-(2-chloro-4-pyridyl)-N'-phenylurea
1-(2-chloropyridin-4-yl)-3-phenylurea
 methanol, 1-[(2-chloro-4-pyridinyl)amino]-1-(phenylimino)-, (E)-
 

Articles:

PubMed:A molecularly imprinted polymer synthesized using β-cyclodextrin as the monomer for the efficient recognition of forchlorfenuron in fruits.
PubMed:The requirement of SEPT2 and SEPT7 for migration and invasion in human breast cancer via MEK/ERK activation.
PubMed:Small molecule perturbations of septins.
PubMed:Septins guide microtubule protrusions induced by actin-depolymerizing toxins like Clostridium difficile transferase (CDT).
PubMed:Proteomic Response and Quality Maintenance in Postharvest Fruit of Strawberry (Fragaria × ananassa) to Exogenous Cytokinin.
PubMed:Analysis of forchlorfenuron and thidiazuron in fruits and vegetables by surface-enhanced Raman spectroscopy after selective solid-phase extraction with modified β-cyclodextrin.
PubMed:Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells.
PubMed:Massive immuno multiresidue screening of water pollutants.
PubMed:Comparison of extraction solvents and sorbents in the quick, easy, cheap, effective, rugged, and safe method for the determination of pesticide multiresidue in fruits by ultra high performance liquid chromatography with tandem mass spectrometry.
PubMed:Identification, synthesis, and safety assessment of forchlorfenuron (1-(2-chloro-4-pyridyl)-3-phenylurea) and its metabolites in kiwifruits.
PubMed:Septin dynamics are essential for exocytosis.
PubMed:Degradation of forchlorfenuron by nitrification and denitrification reactions in the gut and shell biofilm of Limnoperna fortunei.
PubMed:[Determination of 21 plant growth regulator residues in fruits by QuEChERS-high performance liquid chromatography-tandem mass spectrometry].
PubMed:Off-target effects of the septin drug forchlorfenuron on nonplant eukaryotes.
PubMed:An efficient method in breaking of dormancy from Bunium persicum (Boiss) Fedtsch seeds: a valuable herb of Middle East and Central Asia.
PubMed:Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis.
PubMed:Forchlorfenuron detection based on its inhibitory effect towards catalase immobilized on boron nitride substrate.
PubMed:[Effect of forchlorfenuron on fruit morphology and lignans content of Schisandra chinensis].
PubMed:[Monolith column solid-phase extraction coupled with high performance liquid chromatography in online mode for the determination of forchlorfenuron in fruits].
PubMed:Determination of forchlorfenuron in fruits by solid phase or QuECHERS extraction and LC-UV or LC/MS/MS.
PubMed:Recruitment of septin cytoskeletal proteins by botulinum toxin A protease determines its remarkable stability.
PubMed:In silico docking of forchlorfenuron (FCF) to septins suggests that FCF interferes with GTP binding.
PubMed:Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins.
PubMed:Pre-anthesis CPPU low dosage application increases 'Hayward' kiwifruit weight without affecting the other qualitative and nutritional characteristics.
PubMed:[Determination of four plant growth regulator residues in amphisarcas by high performance liquid chromatography-tandem mass spectrometry].
PubMed:Dispersive liquid-liquid microextraction for the determination of three cytokinin compounds in fruits and vegetables by liquid chromatography with time-of-flight mass spectrometry.
PubMed:Dissipation kinetics of forchlorfenuron, 6-benzyl aminopurine, gibberellic acid and ethephon residues in table grapes (Vitis vinifera).
PubMed:Forchlorfenuron disrupts SEPT9_i1 filaments and inhibits HIF-1.
PubMed:Dissipation and residue of forchlorfenuron in citrus fruits.
PubMed:[Determination of six plant growth regulator residues in strawberry by liquid chromatography-quadrupole time of flight mass spectrometry].
PubMed:Development of an immunochromatographic assay based on carbon nanoparticles for the determination of the phytoregulator forchlorfenuron.
PubMed:Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking.
PubMed:Development and validation of a direct competitive monoclonal antibody-based immunoassay for the sensitive and selective analysis of the phytoregulator forchlorfenuron.
PubMed:[Determination of forchlorfenuron and gibberellin acid in the grapes using high performance liquid chromatography-tandem mass spectrometry].
PubMed:Multiresidue analysis of plant growth regulators in grapes by triple quadrupole and quadrupole-time of flight-based liquid chromatography/mass spectrometry.
PubMed:Simultaneous determination of five plant growth regulators in fruits by modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction and liquid chromatography-tandem mass spectrometry.
PubMed:Submembranous septins as relatively stable components of actin-based membrane skeleton.
PubMed:Multiresidue analysis of multiclass plant growth regulators in grapes by liquid chromatography/tandem mass spectrometry.
PubMed:Forchlorfenuron-mimicking haptens: from immunogen design to antibody characterization by hierarchical clustering analysis.
PubMed:Application of plant growth regulators mitigates chlorotic foliar injury by the black pecan aphid (Hemiptera: Aphididae).
PubMed:Hapten synthesis and polyclonal antibody-based immunoassay development for the analysis of forchlorfenuron in kiwifruit.
PubMed:Cellular requirements for the small molecule forchlorfenuron to stabilize the septin cytoskeleton.
PubMed:Analysis of forchlorfenuron in vegetables by LC/TOF-MS after extraction with the buffered QuEChERS method.
PubMed:Production and characterization of monoclonal and polyclonal antibodies to forchlorfenuron.
PubMed:Forchlorfenuron alters mammalian septin assembly, organization, and dynamics.
PubMed:Degradation kinetics of forchlorfenuron in typical grapevine soils of India and its influence on specific soil enzyme activities.
PubMed:Sorption behaviour of forchlorfenuron in soil.
PubMed:Clean-up method of forchlorfenuron in agricultural products for HPLC analysis.
PubMed:Analysis and residue levels of forchlorfenuron (CPPU) in watermelons.
PubMed:[Determination of forchlorfenuron in Chinese gooseberry with dispersive solid phase extraction and HPLC].
PubMed:Determination of forchlorfenuron residues in watermelon by solid-phase extraction and high-performance liquid chromatography.
PubMed:Forchlorfenuron, a phenylurea cytokinin, disturbs septin organization in Saccharomyces cerevisiae.
PubMed:Behaviour of forchlorfenuron residues in grape, soil and water.
PubMed:Induction of high-frequency somatic embryogenesis in geranium (Pelargonium x hortorum Bailey cv Ringo Rose) cotyledonary cultures.
PubMed:Somatic embryogenesis in peanut (Arachis hypogaea L.): stimulation of direct differentiation of somatic embryos by forchlorfenuron (CPPU).
PubMed:[Cytokinins].
PubMed:Cytokinin-specific binding protein in etiolated mung bean seedlings.
 
Notes:
None found
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