Name: | (2E,4E)-hexa-2,4-dienoic acid |
CAS Number: | 110-44-1 | 3D/inchi
|
Other(deleted CASRN): | 1197240-56-4 |
ECHA EINECS - REACH Pre-Reg: | 203-768-7 |
FDA UNII: | X045WJ989B |
Nikkaji Web: | J2.449J |
Beilstein Number: | 1098547 |
MDL: | MFCD00002703 |
CoE Number: | 8085 |
XlogP3: | 1.30 (est) |
Molecular Weight: | 112.12816000 |
Formula: | C6 H8 O2 |
BioActivity Summary: | listing |
NMR Predictor: | Predict (works with chrome, Edge or firefox) |
EFSA/JECFA Comments: |
The JECFA evaluated (E,E)-2,4-hexadienoic acid (CASrn as in Register). CASrn in Register refers to the (E,E)-isomer. Register name to be changed to (E,E)-Hexa-2,4-dienoic acid.
This favouring substance is also called sorbic acid and corresponds to food additive (E-200) |
Category:antimicrobial preservatives, fungistatic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: | Search |
Google Books: | Search |
Google Scholar: with word "volatile" | Search |
Google Scholar: with word "flavor" | Search |
Google Scholar: with word "odor" | Search |
Perfumer and Flavorist: | Search |
Google Patents: | Search |
US Patents: | Search |
EU Patents: | Search |
Pubchem Patents: | Search |
PubMed: | Search |
NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: |
182.3089 | Sorbic acid View - review |
EU SANCO | Sorbic acid View - review |
EU SANCO | Sorbic acid - sorbates (SA) View - review |
EU SANCO | Sorbic acid - sorbates; p-hydroxybenzoates (SA + PHB) View - review |
EU SANCO | Sorbic acid - sorbates; Benzoic acid - benzoates (SA + BA) View - review |
EU SANCO | Sorbic acid - sorbates; Benzoic acid - benzoates; p-hydroxybenzoates (SA + BA + PHB) View - review |
FCN 1214 | Sorbic acid View - notice |
FCN 1833 | Sorbic Acid REPLACES FCN 1305 View - notice |
JECFA Food Flavoring: | 1176 (E,E)-2,4-hexadienoic acid |
JECFA Food Additive: | Sorbic Acid |
GSFA Codex: | Sorbic acid (200) |
DG SANTE Food Flavourings: | 08.085 (E,E)-hexa-2,4-dienoic acid
08.085 (E,E)-sorbic acid |
DG SANTE Food Additives: | (E,E)-hexa-2,4-dienoic acid
(E,E)-sorbic acid |
DG SANTE Food Contact Materials: | (E,E)-hexa-2,4-dienoic acid
(E,E)-sorbic acid |
FEMA Number: | 3921 (E,E)-2,4-hexadienoic acid |
FDA: | No longer provide for the use of these seven synthetic flavoring substances |
FDA Mainterm (SATF): | 110-44-1 ; SORBIC ACID |
FDA Regulation: | FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.118 Colby cheese.
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.123 Cold-pack and club cheese.
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.124 Cold-pack cheese food.
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.169 Pasteurized process cheese.
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.173 Pasteurized process cheese food.
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.179 Pasteurized process cheese spread.
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.187 Semisoft cheeses.
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS Subpart B--Requirements for Specific Standardized Cheese and Related Products Sec. 133.188 Semisoft part-skim cheeses.
FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products Sec. 150.141 Artificially sweetened fruit jelly.
FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products Sec. 150.161 Artificially sweetened fruit preserves and jams.
FDA PART 166 -- MARGARINE Subpart B--Requirements for Specific Standardized Margarine Sec. 166.110 Margarine.
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart I--Multipurpose Additives Sec. 172.872 Methyl ethyl cellulose.
FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use Sec. 177.2260 Filters, resin-bonded.
FDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS Subpart B--Specific Prior-Sanctioned Food Ingredients Sec. 181.23 Antimycotics.
FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE Subpart D--Chemical Preservatives Sec. 182.3089 Sorbic acid.
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Physical Properties:
Appearance: | white powder (est) |
Assay: | 99.00 to 100.00
|
Food Chemicals Codex Listed: | Yes |
Melting Point: | 132.00 to 135.00 °C. @ 760.00 mm Hg
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Boiling Point: | 232.98 °C. @ 760.00 mm Hg (est)
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Acid Value: | 1.00 max. KOH/g
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Vapor Pressure: | 0.020000 mmHg @ 25.00 °C. (est) |
Flash Point: | 261.00 °F. TCC ( 127.22 °C. )
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logP (o/w): | 1.330 |
Soluble in: |
| alcohol | | water, 1910 mg/L @ 30 °C (exp) |
Insoluble in: |
| water |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Alfa Biotechnology |
For experimental / research use only. |
2,4-Hexadienoic acid 98%
|
American International Chemical, LLC. |
SORBIC ACID FCC
|
APAC Chemical |
Sorbic Acid
Odor: characteristic Use: appears as white, free flowing crystalline granules with a mild and characteristic odor. It is slightly soluble in water, and completely soluble in alcohol. Sorbic Acid Kosher is Passover Certified. |
BOC Sciences |
For experimental / research use only. |
SORBIC ACID 95%
|
Covalent Chemical |
Sorbic Acid
|
ECSA Chemicals |
SORBIC ACID
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ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
EMD Millipore |
For experimental / research use only. |
Sorbic Acid
|
Foodchem International |
Sorbic Acid
|
Glentham Life Sciences |
Sorbic acid
|
Graham Chemical |
Sorbic Acid
|
Indenta Group |
Sorbic Acid
|
Indis NV |
For experimental / research use only. |
Sorbic Acid
|
Penta International |
SORBIC ACID NF
|
Penta International |
SORBIC ACID NF/EP GRADE
|
Penta International |
SORBIC ACID
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Prinova |
Sorbic Acid
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Qingdao Dacon Trading |
Sorbic Acid
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Sigma-Aldrich |
2,4-Hexadienoic acid, ≥99%, FCC
|
Certified Food Grade Products |
Silver Fern Chemical |
Sorbic Acid
Odor: characteristic Use: Sorbic acid is used as an antimicrobial agent, fungicide, and preservative in foods. It can also be found in resins, coatings, oils, rubber, plastics, and lubricants. |
Sinofi Food Ingredients |
Sorbic Acid
Odor: characteristic Use: Preservative, Cosmetics, Feed, Tobacco, Mold Inhibitor, Yeast Inhibitor, Bactericide, Antimicrobial, Beverages, Beverage Powder, Soft Drink, Cakes, Cheese, Fish, Fruit Juice, Margarine, Pickled Goods, Salad Dressings, Fresh Salad, Wine, Puddings, Sauces, Baking Food, Sauage, Food Colors, Milk, Wine, Flavoring Agent. |
TCI AMERICA |
For experimental / research use only. |
Sorbic Acid >99.0%(HPLC)(T)
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Tianjin Talent Chemical |
Sorbic Acid
|
United International |
Sorbic Acid
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Safety Information:
Preferred SDS: View |
European information : |
Most important hazard(s): | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-rat LD50 7360 mg/kg Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 63, 1948.
intraperitoneal-rat LD50 800 mg/kg "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4953, 1982.
intraperitoneal-mouse LD50 2820 mg/kg Journal of Pharmacy and Pharmacology. Vol. 21, Pg. 85, 1969.
oral-mouse LD50 3200 mg/kg "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4953, 1982.
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Dermal Toxicity: |
skin-rabbit LD50 > 1000 mg/kg Union Carbide Data Sheet. Vol. 7/14/1965
subcutaneous-mouse LD50 2820 mg/kg Journal of Pharmacy and Pharmacology. Vol. 21, Pg. 85, 1969.
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | antimicrobial preservatives, fungistatic agents |
Recommendation for (E,E)-sorbic acid usage levels up to: | | not for fragrance use.
|
|
Maximised Survey-derived Daily Intakes (MSDI-EU): | 61.00 (μg/capita/day) |
Maximised Survey-derived Daily Intakes (MSDI-USA): | 6.00 (μg/capita/day) |
Threshold of Concern: | 1800 (μg/person/day) |
Structure Class: | I |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 19 |
Click here to view publication 19 |
| average usual ppm | average maximum ppm |
baked goods: | 10.00000 | 14.00000 |
beverages(nonalcoholic): | 2.00000 | 3.00000 |
beverages(alcoholic): | 3.00000 | 5.00000 |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | 3.00000 | 6.00000 |
fruit ices: | - | - |
gelatins / puddings: | 2.00000 | 4.00000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | - |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | 3.00000 | 5.00000 |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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European Food Safety Authority (EFSA) reference(s):
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Flavouring Group Evaluation 70 (FGE.70): Consideration of aliphatic, alicyclic, linear, alpha,beta-unsaturated, di- and trienals and related alcohols, acids and esters evaluated by JECFA (61st meeting) View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 96 (FGE.96): Consideration of 88 flavouring substances considered by EFSA for which EU production volumes / anticipated production volumes have been submitted on request by DG SANCO. Addendum to FGE. 51, 52, 53, 54, 56, 58, 61, 62, 63, 64, 68, 69, 70, 71, 73, 76, 77, 79, 80, 83, 84, 85 and 87. View page or View pdf
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Scientific Opinion on the safety and efficacy of sorbic acid and potassium sorbate when used as technological additives for all animal species View page or View pdf
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Scientific Opinion on the re-evaluation of sorbic acid (E 200), potassium sorbate (E 202) and calcium sorbate (E 203) as food additives View page or View pdf
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Scientific Opinion on the safety and efficacy of sorbic acid and potassium sorbate when used as technological additives for all animal species based on two dossiers from Nutrinova Nutrition Specialties & Food Ingredients GmbH View page or View pdf
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Opinion on the follow-up of the re-evaluation of sorbic acid (E200) and potassium sorbate (E202) as food additives View page or View pdf
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Scientific Opinion on Flavouring Group Evaluation 70, Revision 1 (FGE.70Rev1): consideration of aliphatic, linear, a,ß-unsaturated, di- and trienals and related alcohols, acids and esters evaluated by JECFA (61st-68th-69th meeting) View page or View pdf
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EPI System: View |
NIOSH International Chemical Safety Cards:search |
Chemical Carcinogenesis Research Information System:Search |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
Carcinogenic Potency Database:Search |
EPA Substance Registry Services (TSCA):110-44-1 |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :643460 |
National Institute of Allergy and Infectious Diseases:Data |
SCCNFP:opinion |
WGK Germany:1 |
(2E,4E)-hexa-2,4-dienoic acid |
Chemidplus:0000110441 |
EPA/NOAA CAMEO:hazardous materials |
RTECS:110-44-1 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
(2E,4E)- | hexa-2,4-dienoic acid | (E,E)- | hexa-2,4-dienoic acid | (2E,4E)-2,4- | hexadienoic acid | (E,E)-2,4- | hexadienoic acid | trans-trans-2,4- | hexadienoic acid | trans,trans-2,4- | hexadienoic acid | 2,4- | hexadienoic acid, (2E,4E)- | | panosorb | (E,E)-1,3- | pentadiene-1-carboxylic acid | (E)-1,(E)-3- | pentadiene-1-carboxylic acid | trans-1,trans-3- | pentadiene-1-carboxylic acid | 1,3- | pentadiene-1-carboxylic acid, (E,E)- | trans,trans- | sorbic acid | | sorbic acid FCC | | sorbic acid NF | | sorbistat |
Articles:
PubMed:Quantifying the effect of sorbic acid, heat and combination of both on germination and outgrowth of Bacillus subtilis spores at single cell resolution. |
PubMed:Simultaneous quantification of five proteins and seven additives in dairy products with a heart-cutting two-dimensional liquid chromatography method. |
PubMed:Microencapsulated Sorbic Acid and Pure Botanicals Affect Salmonella Typhimurium Shedding in Pigs: A Close-Up Look from Weaning to Slaughter in Controlled and Field Conditions. |
PubMed:Influence of the antimicrobial compound allyl isothiocyanate against the Aspergillus parasiticus growth and its aflatoxins production in pizza crust. |
PubMed:An environment-friendly procedure for the high performance liquid chromatography determination of benzoic acid and sorbic acid in soy sauce. |
PubMed:The inhibitory effects of sorbate and benzoate against Clostridium perfringens type A isolates. |
PubMed:Dietary exposure estimates for the food preservatives benzoic acid and sorbic acid in the total diet in Taiwan. |
PubMed:HPLC and LC-MS/MS methods for determination of sodium benzoate and potassium sorbate in food and beverages: performances of local accredited laboratories via proficiency tests in Turkey. |
PubMed:Investigation of the solubility enhancement mechanism of rebaudioside D using a solid dispersion technique with potassium sorbate as a carrier. |
PubMed:Effects of different sorbic acid and moisture levels on chemical and microbial qualities of sun-dried apricots during storage. |
PubMed:Strategies to increase the stability of intermediate moisture foods towards Zygosaccharomyces rouxii: the effect of temperature, ethanol, pH and water activity, with or without the influence of organic acids. |
PubMed:Comparative physiological and transcriptional analysis of weak organic acid stress in Bacillus subtilis. |
PubMed:"Effect of sorbic acid on the storage quality of Kaladhi-an acid coagulated milk product". |
PubMed:Inhibitory effects of nisin and potassium sorbate alone or in combination on vegetative cells growth and spore germination of Bacillus sporothermodurans in milk. |
PubMed:Effect of baking improvers on the quality of whole cassava biscuits. |
PubMed:Growth/no growth models for Zygosaccharomyces rouxii associated with acidic, sweet intermediate moisture food products. |
PubMed:Benzoic and sorbic acid in soft drink, milk, ketchup sauce and bread by dispersive liquid-liquid microextraction coupled with HPLC. |
PubMed:Modelling the effect of lactic acid bacteria from starter- and aroma culture on growth of Listeria monocytogenes in cottage cheese. |
PubMed:Distinct effects of sorbic acid and acetic acid on the electrophysiology and metabolism of Bacillus subtilis. |
PubMed:Antifungal agents against Aspergillus niger for rearing rice leaffolder larvae (Lepidoptera: Pyralidae) on artificial diet. |
PubMed:Identification and characterisation of organisms associated with chocolate pralines and sugar syrups used for their production. |
PubMed:Influence of temperature and preserving agents on the stability of cornelian cherries anthocyanins. |
PubMed:Sodium benzoate and potassium sorbate preservatives in Iranian doogh. |
PubMed:Population heterogeneity and dynamics in starter culture and lag phase adaptation of the spoilage yeast Zygosaccharomyces bailii to weak acid preservatives. |
PubMed:Shelf life study of hurdle treated ready-to-eat spiced buffalo meat product stored at 30 ± 3 °C for 7 weeks under vacuum and aerobic packaging. |
PubMed:Sorbate and benzoate in Turkish retail foodstuffs. |
PubMed:Biotechnological production of muconic acid: current status and future prospects. |
PubMed:Evaluating food additives as antifungal agents against Monilinia fructicola in vitro and in hydroxypropyl methylcellulose-lipid composite edible coatings for plums. |
PubMed:Effect of treatments and packaging on the quality of dried carrot slices during storage. |
PubMed:Quantification of the impact of single and multiple mild stresses on outgrowth heterogeneity of Bacillus cereus spores. |
PubMed:Simultaneous determination of sorbic and benzoic acids in milk products using an optimised microextraction technique followed by gas chromatography. |
PubMed:[Formation of trans-1,3-pentadiene in off-flavor food]. |
PubMed:Sorbic acid stress activates the Candida glabrata high osmolarity glycerol MAP kinase pathway. |
PubMed:Optimization of medium composition for cis,cis-muconic acid production by a Pseudomonas sp. mutant using statistical methods. |
PubMed:Online dynamic pH junction-sweeping for the determination of benzoic and sorbic acids in food products by capillary electrophoresis. |
PubMed:Plasma treated polyethylene terephthalate/polypropylene films assembled with chitosan and various preservatives for antimicrobial food packaging. |
PubMed:Simultaneous separation and determination of five organic acids in beverages and fruits by capillary electrophoresis using diamino moiety functionalized silica nanoparticles as pseudostationary phase. |
PubMed:Risk assessment of additives through soft drinks and nectars consumption on Portuguese population: a 2010 survey. |
PubMed:Characterisation of the lipidic components of margarines by 1H Nuclear Magnetic Resonance. |
PubMed:Optimal designs of the median run length based double sampling X chart for minimizing the average sample size. |
PubMed:[Simultaneous determination of twelve sweeteners and nine preservatives in foods by solid-phase extraction and LC-MS/MS]. |
PubMed:Extreme resistance to weak-acid preservatives in the spoilage yeast Zygosaccharomyces bailii. |
PubMed:Potassium sorbate controlled release from corn starch films. |
PubMed:Combined effects of potassium sorbate, hot water and thiabendazole against green mould of citrus fruit and residue levels. |
PubMed:Yeast adaptation to weak acids prevents futile energy expenditure. |
PubMed:Active biodegradable films produced with blends of rice flour and poly(butylene adipate co-terephthalate): effect of potassium sorbate on film characteristics. |
PubMed:Immunoregulatory impact of food antioxidants. |
PubMed:Dispersive liquid-liquid microextraction followed by high-performance liquid chromatography for determination of benzoate and sorbate in yogurt drinks and method optimization by central composite design. |
PubMed:Effect of naturally occurring antimicrobials and chemical preservatives on the growth of Aspergillus Parasiticus. |
PubMed:Degradation of ascorbic acid and potassium sorbate by different Lactobacillus species isolated from packed green olives. |
PubMed:Sorbic and benzoic acid in non-preservative-added food products in Turkey. |
PubMed:Weak-acid preservatives: pH and proton movements in the yeast Saccharomyces cerevisiae. |
PubMed:The application of bioactive compounds from the food industry to control mold growth in indoor waterborne coatings. |
PubMed:Assessing the effect, on animal model, of mixture of food additives, on the water balance. |
PubMed:Comparing organic acids and salt derivatives as antimicrobials against selected poultry-borne Listeria monocytogenes strains in vitro. |
PubMed:[Determination of sixteen food additives in beverage by capillary zone electrophoresis]. |
PubMed:Food avoidance diets for systemic, lip, and oral contact allergy: an american contact alternatives group article. |
PubMed:[Detection of sorbic acid in food by homemade micro-spectrometer analytical system]. |
PubMed:Development of a feed additive to reduce caecal Campylobacter jejuni in broilers at slaughter age: from in vitro to in vivo, a proof of concept. |
PubMed:[Benzene in soft drinks: a study in Florence (Italy)]. |
PubMed:Analysis of nine food additives in red wine by ion-suppression reversed-phase high-performance liquid chromatography using trifluoroacetic acid and ammonium acetate as ion-suppressors. |
PubMed:Application of dispersive solid-phase extraction and ultra-fast liquid chromatography-tandem quadrupole mass spectrometry in food additive residue analysis of red wine. |
PubMed:Impact of sorbic acid on germination and outgrowth heterogeneity of Bacillus cereus ATCC 14579 spores. |
PubMed:Screening of different stress factors and development of growth/no growth models for Zygosaccharomyces rouxii in modified Sabouraud medium, mimicking intermediate moisture foods (IMF). |
PubMed:Multi-detection of preservatives in cheeses by liquid chromatography-tandem mass spectrometry. |
PubMed:[Highly efficient and rapid capillary electrophoretic analysis of seven organic acid additives in beverages using polymeric ionic liquid as additive]. |
PubMed:Mapping the structural requirements of inducers and substrates for decarboxylation of weak acid preservatives by the food spoilage mould Aspergillus niger. |
PubMed:Absolute quantitative analysis for sorbic acid in processed foods using proton nuclear magnetic resonance spectroscopy. |
PubMed:Effect of preservatives on Shiga toxigenic phages and Shiga toxin of Escherichia coli O157:H7. |
PubMed:Effects of benzalkonium chloride and potassium sorbate on airway ciliary activity. |
PubMed:Development of a fast capillary electrophoresis method for determination of carbohydrates in honey samples. |
PubMed:Effects of nisin, EDTA and salts of organic acids on Listeria monocytogenes, Salmonella and native microflora on fresh vacuum packaged shrimps stored at 4 °C. |
PubMed:Susceptibility of food-contaminating Penicillium genus fungi to some preservatives and disinfectants. |
PubMed:Shelf life extension of sugarcane juice using preservatives and gamma radiation processing. |
PubMed:[Influences of ion-suppressors on retention behaviors of nine food additives in reversed-phase high performance liquid chromatographic separation]. |
PubMed:Exposure assessment of food preservatives (sulphites, benzoic and sorbic acid) in Austria. |
PubMed:Effect of diet composition and mixture of selected food additives on the erythrocytic system and iron metabolism in peripheral blood of male rats. |
PubMed:Ultrasound application for the control of decay on apple at different stage of ripening. |
PubMed:Establishing equivalence for microbial-growth-inhibitory effects ("iso-hurdle rules") by analyzing disparate listeria monocytogenes data with a gamma-type predictive model. |
PubMed:pH-stat fed-batch process to enhance the production of cis, cis-muconate from benzoate by Pseudomonas putida KT2440-JD1. |
PubMed:Generation of a catR deficient mutant of P. putida KT2440 that produces cis, cis-muconate from benzoate at high rate and yield. |
PubMed:Development of an RP-HPLC method for the simultaneous determination of benzoic acid, sorbic acid, natamycin and lysozyme in hard and pasta filata cheeses. |
PubMed:[The estimation of intake of selected and permissible preservatives used in food industry among people from Podlaskie voivodeship]. |
PubMed:Antimicrobial effects of weak acids on the survival of Escherichia coli O157:H7 under anaerobic conditions. |
PubMed:Simultaneous determination of some food additives in soft drinks and other liquid foods by flow injection on-line dialysis coupled to high performance liquid chromatography. |
PubMed:Fast and sensitive high performance liquid chromatography analysis of cosmetic creams for hydroquinone, phenol and six preservatives. |
PubMed:Antifungal effectiveness of potassium sorbate incorporated in edible coatings against spoilage molds of apples, cucumbers, and tomatoes during refrigerated storage. |
PubMed:Effects of antimicrobial coating from catfish skin gelatin on quality and shelf life of fresh white shrimp (Penaeus vannamei). |
PubMed:Application of polylactic acid coating with antimicrobials in reduction of Escherichia coli O157:H7 and Salmonella Stanley on apples. |
PubMed:Control of Listeria monocytogenes on cold-smoked salmon using chitosan-based antimicrobial coatings and films. |
PubMed:Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored "Ortanique" mandarins. |
PubMed:[Simultaneous determination of six food additives in meat products by high performance liquid chromatography]. |
PubMed:Antimicrobial activity of weak acids in liquid feed fermentations, and its effects on yeasts and lactic acid bacteria. |
PubMed:Characterization of germination and outgrowth of sorbic acid-stressed Bacillus cereus ATCC 14579 spores: phenotype and transcriptome analysis. |
PubMed:Low occupational exposure to benzene in a petrochemical plant: modulating effect of genetic polymorphisms and smoking habit on the urinary t,t-MA/SPMA ratio. |
PubMed:Impact of sorbic acid on germinant receptor-dependent and -independent germination pathways in Bacillus cereus. |
PubMed:The ensiling capability of a mixture of sodium benzoate, potassium sorbate, and sodium nitrite. |
PubMed:Determination of preservatives by integrative coupling method of headspace liquid-phase microextraction and capillary zone electrophoresis. |
PubMed:Simultaneous determination of electroactive and non-electroactive food preservatives by novel capillary electrophoresis with amperometric detection. |
PubMed:Inhibition of growth and caseinase production of Pseudomonas aeruginosa and Escherichia coli 28 by combination of low pH and NaCl, potassium sorbate or Thymus vulgaris extract. |
PubMed:[Simultaneous determination of various aseptics and sweeteners in milk and dairy products]. |
PubMed:Determination of food grade antioxidants using microemulsion electrokinetic chromatography. |
PubMed:Prevention of intestinal Campylobacter jejuni colonization in broilers by combinations of in-feed organic acids. |
PubMed:Transcriptomic and phenotypic responses of Listeria monocytogenes strains possessing different growth efficiencies under acidic conditions. |
PubMed:Estimated intake of benzoic and sorbic acids in Denmark. |
PubMed:Modeling the efficacy of triplet antimicrobial combinations: yeast suppression by lauric arginate, cinnamic acid, and sodium benzoate or potassium sorbate as a case study. |
PubMed:Simultaneous spectrophotometric determination of benzoic acid, sorbic acid, and ascorbic acid using a net analyte signal-based method. |
PubMed:[Study on development of the principles for determination and evaluation of antimicrobial effectiveness of food preservatives]. |
PubMed:Negative and positive ion mode LC/MS/MS for simple, sensitive analysis of sorbic acid. |
PubMed:Proteolytic activity of beef luncheon fungi as affected by incorporation of some food preservatives. |
PubMed:Does potassium sorbate induce genotoxic or mutagenic effects in lymphocytes? |
PubMed:Evaluation of the efficacy of four weak acids as antifungal preservatives in low-acid intermediate moisture model food systems. |
PubMed:Quantification of sorbic acid using the molecularly imprinted chemiluminescence method with rhodanine derivative. |
PubMed:Growth response of Escherichia coli ATCC 35218 adapted to several concentrations of sodium benzoate and potassium sorbate. |
PubMed:Inhibition of spoilage mould conidia by acetic acid and sorbic acid involves different modes of action, requiring modification of the classical weak-acid theory. |
PubMed:Development and validation of an extensive growth and growth boundary model for Listeria monocytogenes in lightly preserved and ready-to-eat shrimp. |
PubMed:Levels of preservatives (sulfite, sorbate and benzoate) in New Zealand foods and estimated dietary exposure. |
PubMed:Sorbate-nitrite interactions: acetonitrile oxide as an alkylating agent. |
PubMed:Association between quality of cheap and unrecorded alcohol products and public health consequences in Poland. |
PubMed:Effect of agar concentration on the matric potential of glycerol agar media and the germination and growth of xerophilic and non-xerophilic fungi. |
PubMed:Solid-state NMR spectroscopic studies on the interaction of sorbic acid with phospholipid membranes at different pH levels. |
PubMed:Inhibition of Listeria monocytogenes by acetate, benzoate and sorbate: weak acid tolerance is not influenced by the glutamate decarboxylase system. |
PubMed:Antimycotic activity of 5'-prenylisoflavanones of the plant Geoffroea decorticans, against Aspergillus species. |
PubMed:Potassium sorbate residue levels and persistence in citrus fruit as detected by a simple colorimetric method. |
PubMed:Study on the performance of the headspace liquid-phase microextraction, gas chromatography-mass spectrometry in the determination of sorbic and benzoic acids in soft drinks and environmental water samples. |
PubMed:Live-Cell imaging and measurement of intracellular pH in filamentous fungi using a genetically encoded ratiometric probe. |
PubMed:In vivo measurement of cytosolic and mitochondrial pH using a pH-sensitive GFP derivative in Saccharomyces cerevisiae reveals a relation between intracellular pH and growth. |
PubMed:Reactivity of some products formed by the reaction of sorbic acid with sodium nitrite: decomposition of 1,4-dinitro-2-methylpyrrole and ethylnitrolic acid. |
PubMed:Evaluation of urinary biomarkers of exposure to benzene: correlation with blood benzene and influence of confounding factors. |
PubMed:Effect of preservatives on microbial safety and quality of smoked blue catfish (Ictalurus furcatus) steaks during room-temperature storage. |
PubMed:[Compound preservative and cyclamat determinated by gas chromatography]. |
PubMed:Effects of potassium sorbate on postharvest brown rot of stone fruit. |
PubMed:Quantification of hurdles: predicting the combination of effects -- Interaction vs. non-interaction. |
PubMed:Determination of preservatives in meat products by flow injection analysis (FIA). |
PubMed:Determination of benzoic acid and sorbic acid in food products using electrokinetic flow analysis-ion pair solid phase extraction-capillary zone electrophoresis. |
PubMed:Cytogenetic study in cultured human lymphocytes treated with three commonly used preservatives. |
PubMed:Physiological state of single cells of Listeria innocua in organic acids. |
PubMed:Modelling the inhibition of sorbic and benzoic acids on a native yeast cocktail from table olives. |
PubMed:Effect of environmental factors and cell physiological state on Pulsed Electric Fields resistance and repair capacity of various strains of Escherichia coli. |
PubMed:Development and antifungal evaluation of a food-grade U-type microemulsion. |
PubMed:[Biological monitoring in oil refinery workers]. |
PubMed:Effects of commonly used food preservatives on biofilm formation of Streptococcus mutans in vitro. |
PubMed:Microbial growth and the effects of mild acidification and preservatives in refrigerated sweet potato puree. |
PubMed:Sensitive and simple analysis of sorbic acid using liquid chromatography with electrospray ionization tandem mass spectrometry. |
PubMed:Auxotrophy for uridine increases the sensitivity of Aspergillus niger to weak-acid preservatives. |
PubMed:Effect of food preservatives on in situ biofilm formation. |
PubMed:Comprehensive analysis of polar and apolar constituents of butter and margarine by nuclear magnetic resonance, reflecting quality and production processes. |
PubMed:Oral lichenoid lesions and allergy to dental materials. |
PubMed:Potential antimicrobials to control Listeria monocytogenes in vacuum-packaged cold-smoked salmon pâté and fillets. |
PubMed:[Simultaneous determination of 7 kinds of preservatives and saccharin in foods with HPLC, and identification with LC/MS/MS]. |
PubMed:Transcriptome analysis of sorbic acid-stressed Bacillus subtilis reveals a nutrient limitation response and indicates plasma membrane remodeling. |
PubMed:The weak-acid preservative sorbic acid is decarboxylated and detoxified by a phenylacrylic acid decarboxylase, PadA1, in the spoilage mold Aspergillus niger. |
PubMed:Control of browning and microbial growth on fresh-cut apples by sequential treatment of sanitizers and calcium ascorbate. |
PubMed:Combinations of antimycotics to inhibit the growth of molds capable of producing 1,3-pentadiene. |
PubMed:Controlling Listeria monocytogenes on sliced ham and turkey products using benzoate, propionate, and sorbate. |
PubMed:Caffeine induces macroautophagy and confers a cytocidal effect on food spoilage yeast in combination with benzoic acid. |
PubMed:Toxicological evaluation of potassium sorbate added to cigarette tobacco. |
PubMed:Performance of a growth-no growth model for Listeria monocytogenes developed for mayonnaise-based salads: influence of strain variability, food matrix, inoculation level, and presence of sorbic and benzoic acid. |
PubMed:Decarboxylation of sorbic acid by spoilage yeasts is associated with the PAD1 gene. |
PubMed:Fumaric and sorbic acid as additives in broiler feed. |
PubMed:Simultaneous determination of preservatives in soft drinks, yogurts and sauces by a novel solid-phase extraction element and thermal desorption-gas chromatography. |
PubMed:Modelling the behaviour of Listeria monocytogenes in ground pork as a function of pH, water activity, nature and concentration of organic acid salts. |
PubMed:Identification of TLC markers and quantification by HPLC-MS of various constituents in noni fruit powder and commercial noni-derived products. |
PubMed:Microbiological changes occurring in trout fillets (Oncorhynchus mykiss W. 1792) salted and treated with potassium sorbate during production and storage. |
PubMed:[Simultaneous determination of nine kinds of preservatives in foods by HPLC]. |
PubMed:1,3-diene probes for detection of triplet carbonyls in biological systems. |
PubMed:Mycoflora of two types of Portuguese dry-smoked sausages and inhibitory effect of sodium benzoate, potassium sorbate, and methyl p-hydroxybenzoate on mold growth rate. |
PubMed:Inactivation of Salmonella enteritidis and Salmonella senftenberg in liquid whole egg using generally recognized as safe additives, ionizing radiation, and heat. |
PubMed:Bactericidal synergism through enterocin AS-48 and chemical preservatives against Staphylococcus aureus. |
PubMed:Organic acid and formaldehyde treatment of animal feeds to control Salmonella: efficacy and masking during culture. |
PubMed:A simple and rapid method for simultaneous determination of benzoic and sorbic acids in food using in-tube solid-phase microextraction coupled with high-performance liquid chromatography. |
PubMed:A genetic screen identifies mutations in the yeast WAR1 gene, linking transcription factor phosphorylation to weak-acid stress adaptation. |
PubMed:Relationship between sublethal injury and inactivation of yeast cells by the combination of sorbic acid and pulsed electric fields. |
PubMed:On-line preconcentration of weak electrolytes by electrokinetic accumulation in CE: experiment and simulation. |
PubMed:Modelling of the growth-no growth interface of Issatchenkia occidentalis, an olive spoiling yeast, as a function of the culture media, NaCl, citric and sorbic acid concentrations: study of its inactivation in the no growth region. |
PubMed:Weakening of salmonella with selected microbial metabolites of berry-derived phenolic compounds and organic acids. |
PubMed:Inhibition of conidia germination and mycelial growth of Botrytis cinerea by some alternative chemicals. |
PubMed:Production in food of 1,3-pentadiene and styrene by Trichoderma species. |
PubMed:Use of logistic regression with dummy variables for modeling the growth-no growth limits of Saccharomyces cerevisiae IGAL01 as a function of sodium chloride, acid type, and potassium sorbate concentration according to growth media. |
PubMed:FaGT2: a multifunctional enzyme from strawberry (Fragaria x ananassa) fruits involved in the metabolism of natural and xenobiotic compounds. |
PubMed:Effects of sorbate speciation on sorption of selected sulfonamides in three loamy soils. |
PubMed:Inhibition of Listeria monocytogenes in turkey and pork-beef bologna by combinations of sorbate, benzoate, and propionate. |
PubMed:Susceptibility of food-borne bacteria to binary combinations of antimicrobials at selected a(w) and pH. |
PubMed:Physiological characterization of spoilage strains of Zygosaccharomyces bailii and Zygosaccharomyces rouxii isolated from high sugar environments. |
PubMed:Determination of neurotoxin gene expression in Clostridium botulinum type A by quantitative RT-PCR. |
PubMed:High Pdr12 levels in spoilage yeast (Saccharomyces cerevisiae) correlate directly with sorbic acid levels in the culture medium but are not sufficient to provide cells with acquired resistance to the food preservative. |
PubMed:Food preservatives sodium sulfite and sorbic acid suppress mitogen-stimulated peripheral blood mononuclear cells. |
PubMed:Use of experimental design methodology to prepare Maillard reaction products from glucose and cysteine inhibitors of polyphenol oxidase from eggplant (Solanum melongena). |
PubMed:Microbial evolution during storage of seasoned olives prepared with organic acids with potassium sorbate, sodium benzoate, and ozone used as preservatives. |
PubMed:Simultaneous determination of sorbic and benzoic acids in food dressing by headspace solid-phase microextraction and gas chromatography. |
PubMed:Development of an alternative eluent system for Ag+-HPLC analysis of conjugated linoleic acid isomers. |
PubMed:Alkylating potential of potassium sorbate. |
PubMed:Weak acid and alkali stress regulate phosphatidylinositol bisphosphate synthesis in Saccharomyces cerevisiae. |
PubMed:Application of predictive models to estimate Listeria monocytogenes growth on frankfurters treated with organic acid salts. |
PubMed:Determination of vitamin C and preservatives in beverages by conventional capillary electrophoresis and microchip electrophoresis with capacitively coupled contactless conductivity detection. |
PubMed:Occupational contact dermatitis from potassium sorbate in milk transformation plant. |
PubMed:Combined efficacy of nisin and pediocin with sodium lactate, citric acid, phytic acid, and potassium sorbate and EDTA in reducing the Listeria monocytogenes population of inoculated fresh-cut produce. |
PubMed:Kinetic study of the physicochemical and microbiological changes in "seasoned" olives during the shelf-life period. |
PubMed:Naturally occurring antifungal agents against Zygosaccharomyces bailii and their synergism. |
PubMed:High-pressure liquid chromatographic-mass spectrometric determination of sorbic acid in urine: verification of formation of trans,trans-muconic acid. |
PubMed:Simultaneous determination of preservatives (benzoic acid, sorbic acid, methylparaben and propylparaben) in foodstuffs using high-performance liquid chromatography. |
PubMed:The effects of various antifungal additives on the fermentation and aerobic stability of corn silage. |
PubMed:An attempt to optimize potassium sorbate use to preserve low pH (4.5-5.5) intermediate moisture bakery products by modelling Eurotium spp., Aspergillus spp. and Penicillium corylophilum growth. |
PubMed:Study of benzoate, propionate, and sorbate salts as mould spoilage inhibitors on intermediate moisture bakery products of low pH (4.5-5.5). |
PubMed:Microbial content of commercial South African high-moisture dried fruits. |
PubMed:Dietary self-selection for organic acids by the piglet. |
PubMed:Effect of gas environment and sorbate addition on flavor characteristics of irradiated apple cider during storage. |
PubMed:Effect of nisin in combination with EDTA, sodium lactate, and potassium sorbate for reducing Salmonella on whole and fresh-cut cantaloupet. |
PubMed:Prevalence of Clostridium species and behaviour of Clostridium botulinum in gnocchi, a REPFED of italian origin. |
PubMed:Screening the yeast deletant mutant collection for hypersensitivity and hyper-resistance to sorbate, a weak organic acid food preservative. |
PubMed:Effect of weak acid preservatives on growth of bakery product spoilage fungi at different water activities and pH values. |
PubMed:Assessment of the influence of energy under-reporting on intake estimates of four food additives. |
PubMed:The weak acid preservative sorbic acid inhibits conidial germination and mycelial growth of Aspergillus niger through intracellular acidification. |
PubMed:Pentadiene production from potassium sorbate by osmotolerant yeasts. |
PubMed:Purification of bacteriocins produced by lactic acid bacteria. |
PubMed:Influence of antimicrobial agents on the spoilage of a meat-based entomophage diet. |
PubMed:New method for the determination of benzoic and sorbic acids in commercial orange juices based on second-order spectrophotometric data generated by a pH gradient flow injection technique. |
PubMed:Antimicrobial edible films and coatings. |
PubMed:Use of survival analysis and Classification and Regression Trees to model the growth/no growth boundary of spoilage yeasts as affected by alcohol, pH, sucrose, sorbate and temperature. |
PubMed:Quantification of toxin-encoding mRNA from Clostridium botulinum type E in media containing sorbic acid or sodium nitrite by competitive RT-PCR. |
PubMed:Effects of cetylpyridinium chloride, acidified sodium chlorite, and potassium sorbate on populations of Escherichia coli O157:H7, Listeria monocytogenes, and Staphylococcus aureus on fresh beef. |
PubMed:Chemical interactions between additives in foodstuffs: a review. |
PubMed:Effect of prestorage treatmlents and storage conditions on the survival of Salmonella enteritidis PT4 and Listeria monocytogenes on fresh marine and freshwater aquaaculture fish. |
PubMed:Global phenotypic analysis and transcriptional profiling defines the weak acid stress response regulon in Saccharomyces cerevisiae. |
PubMed:Efficacy of sorbates on the control of the growth of Eurotium species in bakery products with near neutral pH. |
PubMed:Weak organic acid stress inhibits aromatic amino acid uptake by yeast, causing a strong influence of amino acid auxotrophies on the phenotypes of membrane transporter mutants. |
PubMed:Zygosaccharomyces kombuchaensis: the physiology of a new species related to the spoilage yeasts Zygosaccharomyces lentus and Zygosaccharomyces bailii. |
PubMed:trans,trans-Muconic acid excretion in relation to environmental exposure to benzene. |
PubMed:Spectrophotometric determination of sorbic and benzoic acids in fruit juices by a net analyte signal-based method with selection of the wavelength range to avoid non-modelled interferences. |
PubMed:Effects of processing treatment and sorbate addition on the flavor characteristics of apple cider. |
PubMed:[Simultaneous rapid determination of eight food additives in foods by reversed-phase high performance liquid chromatography]. |
PubMed:[Simultaneous determination of various food additives by high performance liquid chromatography]. |
PubMed:Lack of sensitivity of urinary trans,trans-muconic acid in determining low-level (ppb) benzene exposure in children. |
PubMed:Effect of sorbic acid administration on urinary trans,trans-muconic acid excretion in rats exposed to low levels of benzene. |
PubMed:Personal exposure to different levels of benzene and its relationships to the urinary metabolites S-phenylmercapturic acid and trans,trans-muconic acid. |
PubMed:Risk assessment of the use of sub-optimal levels of weak-acid preservatives in the control of mould growth on bakery products. |
PubMed:Mutagenicity and DNA-damaging activity caused by decomposed products of potassium sorbate reacting with ascorbic acid in the presence of Fe salt. |
PubMed:Estimates of the mean per capita daily intake of benzoic and sorbic acids in Brazil. |
PubMed:Microbiological and sensory quality of stored croissant-type bakery products depending on external (sorbic acid) and internal (dough, aw value) conditions. |
PubMed:Combined effects of weak acid preservatives, pH and water activity on growth of Eurotium species on a sponge cake. |
PubMed:Simultaneous determination of preservatives in beverages, vinegar, aqueous sauces, and quasi-drug drinks by stir-bar sorptive extraction (SBSE) and thermal desorption GC-MS. |
PubMed:Plasma membrane injury induced by nonyl gallate in Saccharomyces cerevisiae. |
PubMed:Evaluation of food additives and low-toxicity compounds as alternative chemicals for the control of Penicillium digitatum and Penicillium italicum on citrus fruit. |
PubMed:Aspergillus flavus dose-response curves to selected natural and synthetic antimicrobials. |
PubMed:Modeling yeast spoilage in cold-filled ready-to-drink beverages with Saccharomyces cerevisiae, Zygosaccharomyces bailii, and Candida lipolytica. |
PubMed:Staphylococcus aureus growth boundaries: moving towards mechanistic predictive models based on solute-specific effects. |
PubMed:Estimation of preservative concentrations in foods and their daily intake based on official inspection results in Japan in fiscal year 1998. |
PubMed:Occurrence of xerophilic fungi in bakery gingerbread production. |
PubMed:Simultaneous determination of trans-resveratrol and sorbic acid in wine by capillary zone electrophoresis. |
PubMed:Controlled release of water-soluble polymeric complexes of sorbic acid with antifungal activities. |
PubMed:Simultaneous determination of artificial sweeteners, preservatives, caffeine, theobromine and theophylline in food and pharmaceutical preparations by ion chromatography. |
PubMed:Parallel and comparative analysis of the proteome and transcriptome of sorbic acid-stressed Saccharomyces cerevisiae. |
PubMed:The ZbYME2 gene from the food spoilage yeast Zygosaccharomyces bailii confers not only YME2 functions in Saccharomyces cerevisiae, but also the capacity for catabolism of sorbate and benzoate, two major weak organic acid preservatives. |
PubMed:The effects of benzoate and fluoride on dental caries in intact and desalivated rats. |
PubMed:Effects of storage temperature and preservative treatment on shelf life of the pond-raised freshwater fish, silver perch (Bidyanus bidyanus). |
PubMed:Weak acid adaptation: the stress response that confers yeasts with resistance to organic acid food preservatives. |
PubMed:Failure of urinary trans,trans-muconic acid as a biomarker for indoor environmental benzene exposure at PPB levels. |
PubMed:Modelling the effects of (green) antifungals, droplet size distribution and temperature on mould outgrowth in water-in-oil emulsions. |
PubMed:Modelling bacterial spoilage in cold-filled ready to drink beverages by Acinetobacter calcoaceticus and Gluconobacter oxydans. |
PubMed:[Effects of chemical agents on the prevention of fungal contamination during household wheat storage in Cixian county]. |
PubMed:Effect of nitrite and propolis preservative on volatile basic nitrogen changes in meat products. |
PubMed:Acid tolerance of Escherichia coli O157:H7 and its survival in apple juice. |
PubMed:Effect of novel water-soluble polymeric forms of sorbic acid against Fusarium oxysporum f.sp. radicis-cucumerinum. |
PubMed:Influence of various parameters on the browning of potassium sorbate in the presence of amines. |
PubMed:Mutagenicity and genotoxicity of sorbic acid-amine reaction products. |
PubMed:Volatile release from an emulsion: headspace and in-mouth studies. |
PubMed:Prevalence and behaviour of Bacillus cereus in a REPFED of Italian origin. |
PubMed:Modeling the growth boundary of Staphylococcus aureus for risk assessment purposes. |
PubMed:Targeted gene deletion in Zygosaccharomyces bailii. |
PubMed:Effects of food preservatives on Alternaria alternata growth and tenuazonic acid production. |
PubMed:Effect of preservation techniques and food additives on staphylococcal thermonuclease. |
PubMed:Sorbic acid resistance: the inoculum effect. |
PubMed:Mutagenicity and genotoxicity of sorbic acid-amine reaction products. |
PubMed:Inhibition of Aeromonas caviae and A. sobria by sodium choloride, citric acid, ascorbic acid, potassium sorbate and extracts of Thymus vulgaris. |
PubMed:Genotoxicity study of reaction products of sorbic acid. |
PubMed:Simultaneous determination of sweeteners and preservatives in preserved fruits by micellar electrokinetic capillary chromatography. |
PubMed:Heat inactivation of Escherichia coli O157:H7 in apple cider containing malic acid, sodium benzoate, and potassium sorbate. |
PubMed:Isolation and identification of tetracycline resistant lactic acid bacteria from pre-packed sliced meat products. |
PubMed:Lack of specificity of trans,trans-muconic acid as a benzene biomarker after ingestion of sorbic acid-preserved foods. |
PubMed:Growth of Bacillus cereus on solid media as affected by agar, sodium chloride, and potassium sorbate. |
PubMed:Rapid high-performance liquid chromatography method for the analysis of sodium benzoate and potassium sorbate in foods. |
PubMed:Chemical and toxicological studies of products resulting from sorbic acid and methylamine interaction in food conditions. |
PubMed:Effect of common food preservatives on mycelial growth and spore germination of Fusarium oxysporum. |
PubMed:Effects of weak acid preservatives on the growth and thermal death of the yeast Pichia membranifaciens in a commercial apple juice. |
PubMed:Comparing HPLC and UV spectrophotometric analysis methods for determining the stability of sorbic acid in nonionic creams containing lactic acid. |
PubMed:Inhibitory action of potassium sorbate degradation products against Staphylococcus aureus growth in laboratory media. |
PubMed:Long-term use of preservatives on rat nasal respiratory mucosa: effects of benzalkonium chloride and potassium sorbate. |
PubMed:Probabilistic modeling of Saccharomyces cerevisiae inhibition under the effects of water activity, pH, and potassium sorbate concentration. |
PubMed:Zygosaccharomyces lentus: a significant new osmophilic, preservative-resistant spoilage yeast, capable of growth at low temperature. |
PubMed:Survival of Listeria monocytogenes in commercial cheese brines. |
PubMed:Simultaneous determination of antioxidants, preservatives and sweeteners permitted as additives in food by mixed micellar electrokinetic chromatography. |
PubMed:Determination of sorbic acid in urine by gas chromatography-mass spectrometry. |
PubMed:Gas chromatographic flow method for the preconcentration and simultaneous determination of antioxidant and preservative additives in fatty foods. |
PubMed:Inhibition of aflatoxin-producing fungi by Welsh onion extracts. |
PubMed:Modeling the aerobic growth and decline of Staphylococcus aureus as affected by pH and potassium sorbate concentration. |
PubMed:Sol-gel composite films with controlled release of biocides. |
PubMed:Individual and combined effects of vanillin and potassium sorbate on Penicillium digitatum, Penicillium glabrum, and Penicillium italicum growth. |
PubMed:Combinations of intervention treatments resulting in 5-log10-unit reductions in numbers of Escherichia coli O157:H7 and Salmonella typhimurium DT104 organisms in apple cider. |
PubMed:Trans,trans-muconic acid, a biological indicator to low levels of environmental benzene: some aspects of its specificity. |
PubMed:Estimation of the distribution of the maximum theoretical intake for ten additives in France. |
PubMed:Weak organic acid treatment causes a trehalose accumulation in low-pH cultures of Saccharomyces cerevisiae, not displayed by the more preservative-resistant Zygosaccharomyces bailii. |
PubMed:Evidence that sorbic acid does not inhibit yeast as a classic 'weak acid preservative'. |
PubMed:Thermal death rate of ascospores of Neosartorya fischeri ATCC 200957 in the presence of organic acids and preservatives in fruit juices. |
PubMed:Sorbic acid-amine function interactions. |
PubMed:Effects of modified atmosphere packaging and preservatives on the shelf-life of high moisture prunes and raisins. |
PubMed:The pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast. |
PubMed:Prediction of Listeria spp. growth as affected by various levels of chemicals, pH, temperature and storage time in a model broth. |
PubMed:Potato pulp: microbiological characterization, physical modification, and application of this agricultural waste product. |
PubMed:Resistance of yeast flora of labaneh to potassium sorbate and sodium benzoate. |
PubMed:Hsp30, the integral plasma membrane heat shock protein of Saccharomyces cerevisiae, is a stress-inducible regulator of plasma membrane H(+)-ATPase. |
PubMed:Influence of modified atmosphere and preservatives on the growth of Zygosaccharomyces rouxii isolated from dried fruits. |
PubMed:Thermal resistance of Bacillus stearothermophilus spores in different heating systems containing some approved food additives. |
PubMed:Activity of the plasma membrane H(+)-ATPase and optimal glycolytic flux are required for rapid adaptation and growth of Saccharomyces cerevisiae in the presence of the weak-acid preservative sorbic acid. |
PubMed:Comparison of the inhibitory action on Saccharomyces cerevisiae of weak-acid preservatives, uncouplers, and medium-chain fatty acids. |
PubMed:Investigation of a pulsed-laser thermo-optical absorbance detector for the determination of food preservatives separated by capillary electrophoresis. |
PubMed:Prolongation of the keeping quality of Mozzarella cheese by treatment with sorbate. |
PubMed:Effects of Sorbic Acid and Methyl Paraben on Susceptibility of Alfalfa Leafcutting Bees (Megachile rotundata) to Chalkbrood (Ascosphaera aggregata) |
PubMed:Control of microbiological quality and shelf-life of catfish (Clarias gariepinus) by chemical preservatives and smoking. |
PubMed:Heat resistance of Escherichia coli O157:H7 in apple juice. |
PubMed:The effects of potassium sorbate and lactic acid on the shelf-life of vacuum-packed chicken meats. |
PubMed:Determination of benzoic and sorbic acids in packaged vegetable products. Comparative evaluation of methods. |
PubMed:Listeriolysin O secretion by Listeria monocytogenes in the presence of cysteine and sorbate. |
PubMed:Topical benzoic acid induces the increased biosynthesis of prostaglandin D2 in human skin in vivo. |
PubMed:Micellar electrokinetic capillary chromatographic determination of artificial sweeteners in low-Joule soft drinks and other foods. |
PubMed:14C-sorbic acid distribution in the aqueous and non-aqueous extracts of cooked millet dough (fura). |
PubMed:The effect of hydroxycinnamic acids and potassium sorbate on the growth of 11 strains of spoilage yeasts. |
PubMed:Simultaneous determination of sorbic acid, benzoic acid and parabens in foods: a new gas chromatography-mass spectrometry technique adopted in a survey on Italian foods and beverages. |
PubMed:Use of indirect conductimetry to predict the growth of spoilage yeasts, with special consideration of Zygosaccharomyces bailii. |
PubMed:Antimicrobial action of some GRAS compounds against Vibrio vulnificus. |
PubMed:Reaction of sorbic acid in millet and sorghum doughs: reaction with thiols. |
PubMed:Potential growth and control of Salmonella in Hispanic type soft cheese. |
PubMed:Weak acid preservatives block the heat shock response and heat-shock-element-directed lacZ expression of low pH Saccharomyces cerevisiae cultures, an inhibitory action partially relieved by respiratory deficiency. |
PubMed:Changes in fatty acid composition of various lipid components of Zygosaccharomyces rouxii as influenced by solutes, potassium sorbate and incubation temperature. |
PubMed:[The influence of potassium sorbate addition on the quality of pickled zucchini fruit]. |
PubMed:Evaluation of phototoxic properties of some food additives: sulfites exhibit prominent phototoxicity. |
PubMed:Fate of enterohemorrhagic Escherichia coli O157:H7 in apple cider with and without preservatives. |
PubMed:Effects of potassium sorbate on growth and penicillic acid production by Aspergillus ochraceus and Penicillium aurantiogriseum. |
PubMed:Effect of potassium sorbate and pH on the survival of Staphylococcus aureus in saturated sugar solutions. |
PubMed:Effect of three preservatives on the growth of Bacillus cereus, Vero cytotoxigenic Escherichia coli and Staphylococcus aureus, on plates with gradients of pH and sodium chloride concentration. |
PubMed:Microculture model studies on the effect of sorbic acid on Penicillium chrysogenum, Cladosporium cladosporioides and Ulocladium atrum at different pH levels. |
PubMed:Development and use of a selective medium for isolation of Leuconostoc spp. from vegetables and dairy products. |
PubMed:Interactive effects of solutes, potassium sorbate and incubation temperature on growth, heat resistance and tolerance to freezing of Zygosaccharomyces rouxii. |
PubMed:Effects of food preservatives on growth and metabolism of plaque bacteria in vitro and in vivo. |
PubMed:Effects of potassium sorbate on growth patterns, morphology, and heat resistance of Zygosaccharomyces rouxii at reduced water activity. |
PubMed:Culture media for non-sporulating gram-positive food spoilage bacteria. |
PubMed:The potential genotoxicity of sorbates: effects on cell cycle in vitro in V79 cells and somatic mutations in Drosophila. |
PubMed:Nutritional aspects of food preservatives. |
PubMed:Reaction of sorbic acid in wheat flour doughs: reaction with thiols. |
PubMed:Kinetics of the reaction of sorbic acid with sulphite species. |
PubMed:Effect of some food preservatives on aflatoxin production. |
PubMed:Genotoxicity and cell transformation studies with sorbates in Syrian hamster embryo fibroblasts. |
PubMed:Analysis of acesulfame-K, saccharin and preservatives in beverages and jams by HPLC. |
PubMed:[Production of a carp-based hamburger-like product by reducing the water activity]. |
PubMed:Limiting bacterial contamination of enteral nutrient solutions: 6-year history with reduction of contamination at two institutions. |
PubMed:Evaluation of the genotoxic potential of sorbic acid and potassium sorbate. |
PubMed:Fungal contamination of Kashar cheese in Turkey. |
PubMed:Effect of preservatives on patulin production by Penicillium expansum. |
PubMed:Effect of chemical treatments on the micro-organisms associated with malting of sorghum grains and sorghum malt. |
PubMed:Action of sorbic acid on Staphylococcus metabolism: a microcalorimetric investigation. |
PubMed:[A demand for authorization for the use of sorbic acid and its salts in acidified, refrigerated salads]. |
PubMed:Metabolism of 1,4-dinitro-2-methylpyrrole, a mutagen formed by a sorbic acid-nitrite reaction, by intestinal bacteria. |
PubMed:[Preservatives and dental caries. Can preservatives in food and beverages influence oral health?]. |
PubMed:The combined effect of incubation temperature, pH and sorbic acid on the probability of growth of non-proteolytic, type B Clostridium botulinum. |
PubMed:Food applications of sorbic acid and its salts. |
PubMed:Effect of surfactants and dispersed components on the activity and reactivity of sorbic acid. |
PubMed:Nucleophilic reactions of sorbic acid. |
PubMed:Stability of sorbic acid in intermediate moisture systems. |
PubMed:Toxicology of sorbic acid and sorbates. |
PubMed:Fungal metabolites of sorbic acid. |
PubMed:[Preparation of microbial silage from fish of underutilized species]. |
PubMed:Re-examination of potassium sorbate and sodium sorbate for possible genotoxic potential. |
PubMed:Mould growth on black table olives and prevention by sorbic acid, methyl-eugenol and spice essential oil. |
PubMed:Potential for the development of tolerance by Aspergillus amstelodami, A. repens and A. ruber after repeated exposure to potassium sorbate. |
PubMed:[Use of gas chromatography for determining benzoic and sorbic acid levels in orange beverage and tomato concentrate]. |
PubMed:Survival and growth of food poisoning bacteria following inoculation into cottage cheese varieties. |
PubMed:[The health status and metabolic indicators in calves fed colostrum and first milk preserved with potassium sorbate and milk replacements]. |
PubMed:The response of Gluconobacter oxydans to sorbic and benzoic acids. |
PubMed:Morphological changes in putrefactive anaerobe 3679 (Clostridium sporogenes) induced by sorbate, hydrochloric acid, and nitrite. |
PubMed:Spectrophotometric method for the determination of sorbic acid in various food samples with iron(III) and 2-thiobarbituric acid as reagents. |
PubMed:Simultaneous determination of the nine food additives using high-performance liquid chromatography. |
PubMed:The relationship of insects to the deterioration of stored grain by fungi. |
PubMed:Use of MRSD medium and the hydrophobic grid membrane filter technique to differentiate between pediococci and lactobacilli in fermented meat and starter cultures. |
PubMed:Determination of seven artificial sweeteners in diet food preparations by reverse-phase liquid chromatography with absorbance detection. |
PubMed:Reverse-phase liquid chromatographic determination of benzoic and sorbic acids in fresh cheese. |
PubMed:Burning mouth syndrome due to nicotinic acid esters and sorbic acid. |
PubMed:Effects of food components and additives on the formation of nitrosamides. |
PubMed:Inhibitory effects of selected Turkish spices and oregano components on some foodborne fungi. |
PubMed:Influence of organic acids on heat resistance characteristics of Talaromyces flavus ascospores. |
PubMed:[Use of sorbic acid (E 200) and its potassium (E 202) and calcium (E 203) salts for the preservation of vegetable pastes destined for baked products]. |
PubMed:[Potassium sorbate, pH and aqueous activity as inhibitors of the growth of Staphylococcus aureus]. |
PubMed:Hypersensitivity reactions to food additives. |
PubMed:Reverse-phase liquid chromatographic determination of benzoic and sorbic acids in foods. |
PubMed:[Results of studies in chronic urticaria with special reference to nutritional factors]. |
PubMed:Effects of natamycin and potassium sorbate on growth and aflatoxin production in olives. |
PubMed:Metabolic aspects of antioxidants and preservatives. |
PubMed:Synergistic effects of weak-acid preservatives and pH on the growth of Zygosaccharomyces bailii. |
PubMed:[Adverse reactions to food preservatives]. |
PubMed:Studies on the analysis of food additives by high-performance liquid chromatography. V. Simultaneous determination of preservatives and saccharin in foods by ion-pair chromatography. |
PubMed:Potential for Development of Tolerance by Penicillium digitatum and Penicillium italicum after Repeated Exposure to Potassium Sorbate. |
PubMed:[Preservation of margarine in fungicidal paper]. |
PubMed:Simultaneous gas chromatographic determination of carboxylic acids in soft drinks and jams. |
PubMed:Evaluation of 1,3-pentadiene for mutagenicity by the Salmonella/mammalian microsome assay. |
PubMed:Effect of anti-oxidants on growth and lactic acid production by Streptococcus mutans. |
PubMed:Inhibition by antimicrobial food additives of ochratoxin A production by Aspergillus sulphureus and Penicillium viridicatum. |
PubMed:Comparative effects of antifungal compounds on the nutritional value of diets containing moldy corn for broiler chicks. |
PubMed:Effects of sorbic acid feed fungistat on the intestinal microflora of floor-reared broiler chickens. |
PubMed:[Chemical preservation of food]. |
PubMed:[Sodium sorbate as a preservative for ready-to-eat foods]. |
PubMed:Effects of sodium nitrite and potassium sorbate on in vitro cultured mammalian cells. |
PubMed:Extraction of organic acids by ion-pair formation with tri-n-octylamine. Part 6. Determination of sorbic acid, benzoic acid, and saccharin in yogurt. |
PubMed:The effect of sorbic acid and esters of p-hydroxybenzoic acid on the protonmotive force in Escherichia coli membrane vesicles. |
PubMed:Benzoic acid and sorbic acid in foods quantitative determination by gas chromatography. |
PubMed:The effect of food preservatives on pH homeostasis in Escherichia coli. |
PubMed:[Effect of potassium sorbate on the growth of Yersinia enterocolitica]. |
PubMed:Extraction of organic acids by ion-pair formation with tri-n-octylamine. Part V. Simultaneous determination of synthetic dyes, benzoic acid, sorbic acid, and saccharin in soft drinks and lemonade syrups. |
PubMed:Effects of sorbic acid and its salts on chromosome aberrations, sister chromatid exchanges and gene mutations in cultured Chinese hamster cells. |
PubMed:Influence of combinations of Lactobacillus lactis and potassium sorbate on growth of psychrotrophs in raw milk. |
PubMed:Gas-liquid chromatographic determination of benzoic acid and sorbic acid in foods: NMKL collaborative study. |
PubMed:Effect of preservatives on the germination and growth of thermally injured fungal spores. |
PubMed:Review: putative mutagens and carcinogens in foods. II: sorbate and sorbate-nitrite interactions. |
PubMed:Food additives and food components in total diets in the Netherlands. |
PubMed:Drug-nitrite interactions in human saliva: effects of food constituents on carcinogenic N-nitrosamine formation. |
PubMed:A bacteriostatic mixture for milk samples and its effect on bacteriological, cytological and chemical compositional analysis. |
PubMed:Perioral contact urticaria from sorbic acid and benzoic acid in a salad dressing. |
PubMed:Nitrite, nitrite alternatives, and the control of Clostridium botulinum in cured meats. |
PubMed:[Mayonnaise eczema in a day nursery]. |
PubMed:Effect of five cycle rapid freeze-thaw treatment in conjunction with various chemicals for the reduction of Salmonella typhimurium. |
PubMed:Evaluation of the mutagenicity of sorbic acid-sodium nitrite reaction products. |
PubMed:Recurrent urticaria: clinical investigation of 330 patients. |
PubMed:Physiological criteria and mycotoxin production as AIDS in identification of common asymmetric penicillia. |
PubMed:Chemical aspects of mutagen formation by sorbic acid-sodium nitrite reaction. |
PubMed:Combined effects of solutes and food preservatives on rates of inactivation of and colony formation by heated spores and vegetative cells of molds. |
PubMed:Prevention of surface mold growth on Italian dry sausage by natamycin and potassium sorbate. |
PubMed:[Agents for the aerosol disinfection of the air in meat freezers]. |
PubMed:An actidione resistant Candida tropicalis from custard apple juice. |
PubMed:Desmutagenic actions of ascorbic acid and cysteine on a new pyrrole mutagen formed by the reaction between food additives; sorbic acid and sodium nitrite. |
PubMed:Comparison of anti-Vibrio activities of potassium sorbate, sodium benzoate, and glycerol and sucrose esters of fatty acids. |
PubMed:Evaluation of the mutagenicity of sorbic acid-sodium nitrite reaction products produced in bacon-curing brines. |
PubMed:Spectrophotometric determination of sulfites, benzoates, sorbates, ascorbates, and added blood in ground beef: collaborative study. |
PubMed:[Isotachophoretic determination of preservatives (author's transl)]. |
PubMed:[Various methods for the determination of preservatives in food. I. Extraction and spectrophotometric determinations (author's transl)]. |
PubMed:Effect of processing variables on the outgrowth of Clostridium sporogenes PA 3679 spores in comminuted meat cured with sorbic acid and sodium nitrite. |
PubMed:Possible use of dietary surveys to assess intake of food additives. |
PubMed:Gas chromatographic determination of preservatives in rennet. |
PubMed:Sodium nitrite and sorbic acid effects on Clostridium botulinum spore germination and total microbial growth in chicken frankfurter emulsions during temperature abuse. |
PubMed:Determination of food preservatives and saccharin by high-performance liquid chromatography. |
PubMed:[Determination of sorbic acid, its salts and salicylic acid in food products of animal origin]. |
PubMed:Analysis of sorbic acid in dried prunes by gas chromatography. |
PubMed:System for evaluating clostridial inhibition in cured meat products. |
PubMed:Inhibition of nitrosamine formation in vitro by sorbic acid. |
PubMed:[Effects of sorbic acid (food additive) on preservation of "Miso" (author's transl)]. |
PubMed:[Effects of sorbic acid (food additive) on preservation of "Tsukudani" (author's transl)]. |
PubMed:Spectrophotometric determination of some preservatives in milk. |
PubMed:[Food additives and their possible genetic toxicity; microbiological determination]. |
PubMed:[Pathogenic factors in foodstuffs of animal origin. 1. Food additives]. |
PubMed:[Re--estimation of preservation effectiveness of potassium sorbate (food additive) in jams and marmalade (author's transl)]. |
PubMed:Growth and toxin production by Clostridium botulinum in moldy tomato juice. |
PubMed:Effectiveness of various food preservatives in controlling the outgrowth of Byssochlamys nivea ascospores. |
PubMed:Long-term toxicity of parasorbic acid in mice. |
PubMed:Long-term toxicity of parasorbic acid in rats. |
PubMed:Long-term toxicity studies of sorbic acid in mice. |
PubMed:Letter: Rapid analysis of potassium sorbate in dried prunes by ultraviolet or colorimetric procedures. |
PubMed:Rapid screening procedure for the determination of preservatives in ground beef: sulfites, benzoates, sorbates, and ascorbates. |
PubMed:Determination of benzoic and sorbic acids in orange juice. |
PubMed:Generation of mutagenic compound(s) by a reaction between sorbci acid and nitrite. |
PubMed:Problems posed by essential food preservatives. |
PubMed:Automated analysis of benzoic acid in food: colorimetric determination after continuous volatilization. |
PubMed:Spectrophotometric estimation of benzoic and sorbic acids. |
PubMed:Long-term toxicity of sorbic acid in the rat. |
PubMed:Improved method for the estimation of parasorbic acid in sorbic acid. |
PubMed:A preliminary study of the suitability of sorbic acid for use as a preservative in cat food preparations. |
PubMed:Rapid spectrophotometric method for the determination of sorbic acid in fresh dairy products. |
PubMed:[Effect of food preservatives on the activity of plant and animal catalase and peroxidase. I. Effect of benzoic acid, sodium benzoate, sorbic acid and potassium sorbate on the activity of catalase and peroxidase of seedlings of Lepidium sativum L]. |
PubMed:Collaborative study of the colorimetric determination of sorbic acid in cheese. |
PubMed:Quantitative determination of sorbic acid in cheddar cheese by gas-liquid chromatography. |
PubMed:[Sorbic acid and sorboylpalmitate against aflatoxin building in bread]. |
PubMed:[Effects of food preservatives on the survival rate of rats following whole-body irradiation. 2. I. Lactic acid, II. Lactose, 3. Sorbic acid, IV. Sodium phosphate]. |
PubMed:Effect of sorbic acid on the grpwtj pf sp growth of some species of yeast. |
PubMed:Growth of Staphylococcus aureus MF31 on the top and cut surfaces of Southern custard pies. |
PubMed:Bloater Formation by Gas-forming Lactic Acid Bacteria in Cucumber Fermentations. |
PubMed:Preservation of cheese with combined use of gamma-rays and sorbic acid. |
PubMed:[Attempts at killing Salmonellae in duck egg compounds; addition of ammonia, benzoic acid, p-hydroxybenzoic acid--ethyl ester and sorbic acid]. |
PubMed:[THE BROMINATION METHOD FOR THE DIFFERENTIATION OF SORBIC ACID AND BENZOIC ACID ON PAPER CHROMATOGRAPHY]. |
PubMed:[The "in vitro" and "in vivo" effects of sorbic acid. Preservation of foods and inoculation in chick embryos]. |
PubMed:Influence of sorbic acid on populations and species of yeasts occurring in cucumber fermentations. |
PubMed:[Rapid method for the detection of sorbic acid in foods]. |
PubMed:[Sorbic acid in food preservation]. |
PubMed:Sorbic acid as a selective agent in cucumber fermentations. II. Effect of sorbic acid on the yeast and lactic acid fermentations in brined cucumbers. |
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