beta-naphthol
2-hydroxynaphthalene

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  CODE105799 CODE105799
  Product(s):
  135-19-3 Tolnaflate Impurity A
  One of the impurities of Tolnaftate, which could be used as an Antifungal agent.

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  Charkit Chemical Corporation

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  NAPHTHOL, BETA-

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  GK1330 2-Naphthol

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  14-01200 beta-NAPHTHOL

Name: naphthalen-2-ol CAS Number: 135-19-3 3D/inchi Other(deleted CASRN): 860440-31-9 ECHA EINECS - REACH Pre-Reg: 205-182-7 FDA UNII: P2Z71CIK5H Nikkaji Web: J2.530E Beilstein Number: 742134 MDL: MFCD00004067 XlogP3: 2.70 (est) Molecular Weight: 144.17296000 Formula: C10 H8 O BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:pharmaceuticals / chemical synthisis   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search FDA Mainterm (IAUFC): 135-19-3 ; BETA-NAPHTHOL   Physical Properties: Appearance: colorless crystalline solid (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Melting Point: 122.30 °C. @ 760.00 mm Hg Boiling Point: 285.00 to 286.00 °C. @ 760.00 mm Hg Boiling Point: 145.00 to 146.00 °C. @ 10.00 mm Hg Vapor Pressure: 0.002000 mmHg @ 25.00 °C. (est) Flash Point: 291.00 °F. TCC ( 144.00 °C. ) (est) logP (o/w): 2.700 Soluble in:   water, 755 mg/L @ 25 °C (exp)   water, 1512 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: BOC Sciences For experimental / research use only. Tolnaflate Impurity A Odor: characteristic Use: One of the impurities of Tolnaftate, which could be used as an Antifungal agent. Charkit Chemical NAPHTHOL, BETA- EMD Millipore For experimental / research use only. beta-Naphthol for synthesis sds ExtraSynthese For experimental / research use only. beta-Naphthol (GC) ≥99% Glentham Life Sciences 2-Naphthol Indenta Group beta-Naphthol Penta International beta-NAPHTHOL Santa Cruz Biotechnology For experimental / research use only. beta-Naphthol Sigma-Aldrich: Aldrich For experimental / research use only. beta-Naphthol 99% sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-cat LDLo 100 mg/kg "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. oral-guinea pig LD50 1335 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 30(9), Pg. 22, 1965. intraperitoneal-mouse LD50 97500 mg/kg European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 381, 1978. oral-mouse LDLo 100 mg/kg "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. oral-rabbit LDLo 3800 mg/kg Yakkyoku. Pharmacy. Vol. 31, Pg. 1499, 1980. unreported-rabbit LDLo 3800 mg/kg Yakkyoku. Pharmacy. Vol. 32, Pg. 605, 1981. oral-rat LD50 1960 mg/kg Gigiena Truda i Professional'naya Patologiya v Estonskoi SSR. Labor Hygiene and Occupational Pathology in the Estonian SSR. Vol. 8, Pg. 145, 1972. Dermal Toxicity: subcutaneous-guinea pig LDLo 2670 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 186, Pg. 195, 1937. subcutaneous-mouse LDLo 100 mg/kg Zeitschrift fuer Hygiene und Infektionskrankheiten. Vol. 64, Pg. 113, 1909. skin-rabbit LD50 > 10000 mg/kg BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 26-4/1973 subcutaneous-rabbit LDLo 3000 mg/kg "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. subcutaneous-rat LDLo 2940 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SLEEP BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 186, Pg. 195, 1937. Inhalation Toxicity: inhalation-rat LC50 > 770 mg/m3/1H GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 26-4/1973   Safety in Use Information: Category: pharmaceuticals / chemical synthisis Recommendation for beta-naphthol usage levels up to:   not for fragrance use.   Recommendation for beta-naphthol flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View NIOSH International Chemical Safety Cards:search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA GENetic TOXicology:Search EPA Substance Registry Services (TSCA):135-19-3 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :8663 National Institute of Allergy and Infectious Diseases:Data WGK Germany:2 naphthalen-2-ol Chemidplus:0000135193 RTECS:135-19-3   References:   naphthalen-2-ol NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 135-19-3 Pubchem (cid): 8663 Pubchem (sid): 134975404   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Indirect Additives used in Food Contact Substances: View CHEBI: View CHEMBL: View KEGG (GenomeNet): C11713 HMDB (The Human Metabolome Database): HMDB12322 FooDB: FDB000877 Export Tariff Code: 2907.15.00.10 ChemSpider: View Wikipedia: View Formulations/Preparations: grade: technical, sublimed, resublimed   Potential Blenders and core components note None Found   Potential Uses:   anticeptic   deodorants   germicid   Occurrence (nature, food, other):note   not found in nature   Synonyms:   azogen developer A   betanaphthol   C.I. azoic coupling component 1   C.I. developer 5   developer A   developer BN   developer NA 2- hydroxynaphthalene b- hydroxynaphthalene beta- hydroxynaphthalene   microcidin 2- naftol   naphthalen-2-ol 2- naphthalenol 2- naphthol b- naphthol   naphthol B b- naphthyl alcohol beta- naphthyl alcohol beta- naphthyl hydroxide 2- napththol   Articles:   None found yet. Try the PubMed Search.

Notes: Trace constit. of essential oils 2-Naphthol is a colorless crystalline solid and an isomer of 1-naphthol, differing by the location of the hydroxyl group on naphthalene. The naphthols are naphthalene homologues of phenol, with the hydroxyl group being more reactive than in the phenols. 2-Naphthol has several different uses including dyes, pigments, fats, oils, insecticides, pharmaceuticals, perfumes, antiseptics, synthesis of fungicides, and antioxidants for rubber. Detection of 2-Naphthol in urine usually results from long-term persistent exposure to pesticides such as chlorpyrifos, but also due to exposure to naphthalene in older types of mothballs, fires that produce polyaromatic hydrocarbons (PAHs), and tobacco smoke.; 2-Naphthol, or ?-naphthol, is a colorless crystalline solid with the formula C10H7OH. It is an isomer of 1-naphthol, differing by the location of the hydroxyl group on naphthalene. The naphthols are naphthalene homologues of phenol, with the hydroxyl group being more reactive than in the phenols. Both isomers are soluble in simple alcohols, ethers, and chloroform. They can be used in the production of dyes and in organic synthesis. For example, 2-naphthol reacts to form BINOL.