EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

beta-cyclodextrin
dextrin, b-cyclo

Supplier Sponsors

CAS Number: 7585-39-9Picture of molecule3D/inchi
Other(deleted CASRN):1187028-35-8
ECHA EINECS - REACH Pre-Reg:231-493-2
FDA UNII: JV039JZZ3A
Beilstein Number:0078623
MDL:MFCD00078139
XlogP3-AA:-15.00 (est)
Molecular Weight:1134.99190000
Formula:C42 H70 O35
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:carrier solvents, encapsulating agent for food additives, flavorings, stabilizers and absorbents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 74 Beta-cyclodextrin View - notice PDF
EU SANCO Beta-cyclodextrin View - review
JECFA Food Additive: beta-Cyclodextrin
GSFA Codex: Cyclodextrin, beta- (459)
DG SANTE Food Additives:beta-cyclodextrin
DG SANTE Food Contact Materials:beta-cyclodextrin
FEMA Number:4028 beta-cyclodextrin
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):7585-39-9 ; BETA-CYCLODEXTRIN
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 260.00 °C. @ 760.00 mm Hg
Flash Point:1627.00 °F. TCC ( 885.90 °C. ) (est)
logP (o/w):-13.960 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage:store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol, slightly
 water, hot
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor Type: odorless
Odor Strength:none
Odor Description:at 100.00 %. odorless
Flavor Type: sweet
sweet
Taste Description: slightly sweet
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: absorbents
chelating agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Cyclomaltoheptaose
Glentham Life Sciences
beta-Cyclodextrin
Maypro Industries
Cyclodextrin
Penta International
CYCLODEXTRIN
Santa Cruz Biotechnology
For experimental / research use only.
beta-Cyclodextrin
Sigma-Aldrich
b-Cyclodextrin, produced by Wacker Chemie AG, Burghausen, Germany
sds
Certified Food Grade Products
TCI AMERICA
For experimental / research use only.
beta-Cyclodextrin >95.0%(LC)
sds
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 18800 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 26, Pg. 287, 1983.

intravenous-rat LD50 1008 mg/kg
American Journal of Pathology. Vol. 83, Pg. 367, 1976.

intraperitoneal-rat LD50 356 mg/kg
"Proceedings of the International Symposium on Cyclodextrins, 1st, 1981," Szejtli, J., ed., Hingham, MA, Kluwer Academic Pub., 1982Vol. 1, Pg. 109, 1982.

oral-mouse LD50 > 12500 mg/kg
Pesticide Science. Vol. 11, Pg. 134, 1980.

intraperitoneal-mouse LD50 330 mg/kg
"Proceedings of the International Symposium on Cyclodextrins, 1st, 1981," Szejtli, J., ed., Hingham, MA, Kluwer Academic Pub., 1982Vol. 1, Pg. 109, 1982.

Dermal Toxicity:
subcutaneous-rat LD50 3700 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 26, Pg. 287, 1983.

subcutaneous-mouse LD50 412 mg/kg
"Proceedings of the International Symposium on Cyclodextrins, 1st, 1981," Szejtli, J., ed., Hingham, MA, Kluwer Academic Pub., 1982Vol. 1, Pg. 109, 1982.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
carrier solvents, encapsulating agent for food additives, flavorings, stabilizers and absorbents
Recommendation for beta-cyclodextrin usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 21
Click here to view publication 21
 average usual ppmaverage maximum ppm
baked goods: 5000.000005000.00000
beverages(nonalcoholic): 3000.000003000.00000
beverages(alcoholic): --
breakfast cereal: 5000.000005000.00000
cheese: 4000.000004000.00000
chewing gum: 5000.000005000.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: 5000.000005000.00000
granulated sugar: --
gravies: --
hard candy: 4000.000004000.00000
imitation dairy: --
instant coffee / tea: 3000.000003000.00000
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: 5000.000005000.00000
soft candy: --
soups: 2000.000002000.00000
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Re-evaluation of ß-cyclodextrin (E 459) as a food additive
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):7585-39-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24238
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
Chemidplus:0007585399
RTECS:GU2293000 for cas# 7585-39-9
 
References:
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7585-39-9
Pubchem (cid):24238
Pubchem (sid):134987124
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
KEGG (GenomeNet):C13183
HMDB (The Human Metabolome Database):HMDB29926
FooDB:FDB001185
Export Tariff Code:3505.10.0020
FDA Listing of Food Additive Status:View
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 absorbants
 chelating agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 betadex
 cyclodextrin
beta-cyclodextrin
 cycloheptaamylose
 cycloheptaglucan
 cycloheptaglucosan
 cycloheptapentylose
 cyclomaltoheptaose
 dextrin, b-cyclo
 kleptose
 rhodocap N
 ringdex B
 

Articles:

Google Patents:Cyclodextrin flavor delivery systems
PubMed:Study of production and pyrolysis characteristics of sweet orange flavor-β-cyclodextrin inclusion complex.
J-Stage:The Aqueous Solubility and Thermal Stability of a-Lipoic Acid Are Enhanced by Cyclodextrin
PubMed:Comparative study of flavor in cholesterol-removed Gouda cheese and Gouda cheese during ripening.
PubMed:Off-flavor precursors in soy protein isolate and novel strategies for their removal.
PubMed:Effects of cyclodextrins on the flavor of goat milk and its yogurt.
PubMed:Microencapsulated antimicrobial compounds as a means to enhance electron beam irradiation treatment for inactivation of pathogens on fresh spinach leaves.
PubMed:Sensory properties of ginseng solutions modified by masking agents.
PubMed:Rational development of taste masked oral liquids guided by an electronic tongue.
PubMed:The accelerated ripening of cholesterol-reduced Cheddar cheese by crosslinked beta-cyclodextrin.
PubMed:Distribution and organoleptic impact of sotolon enantiomers in dry white wines.
PubMed:Effect of beta-cyclodextrin on aroma release and flavor perception.
PubMed:Enantioselective analysis of methyl-branched alcohols and acids in rhubarb (Rheum rhabarbarum L.) stalks.
PubMed:Biogenetic studies in Syringa vulgaris L.: synthesis and bioconversion of deuterium-labeled precursors into lilac aldehydes and lilac alcohols.
PubMed:Removal of cholesterol from Cheddar cheese by beta-cyclodextrin.
PubMed:Cyclodextrin encapsulation to prevent the loss of l-menthol and its retention during drying.
PubMed:Study of interaction phenomena between aroma compounds and carbohydrate matrixes by inverse gas chromatography.
PubMed:Encapsulation of lemon oil by paste method using beta-cyclodextrin: encapsulation efficiency and profile of oil volatiles.
PubMed:Restricted access chiral stationary phase synthesized via reversible addition-fragmentation chain-transfer polymerization for direct analysis of biological samples by high performance liquid chromatography.
PubMed:Distribution and organoleptic impact of ethyl 2-methylbutanoate enantiomers in wine.
PubMed:Method for the determination of catechin and epicatechin enantiomers in cocoa-based ingredients and products by high-performance liquid chromatography: First Action 2013.04.
PubMed:Mutations enhance β-cyclodextrin specificity of cyclodextrin glycosyltransferase from Bacillus circulans.
PubMed:New type of chitosan/2-hydroxypropyl-β-cyclodextrin composite membrane for gallic acid encapsulation and controlled release.
PubMed:Fixation-induced cell blebbing on spread cells inversely correlates with phosphatidylinositol 4,5-bisphosphate level in the plasma membrane.
PubMed:Nanosilica sol leads to further increase in polyethylene glycol (PEG) 1000-enhanced thermostability of β-cyclodextrin glycosyltransferase from Bacillus circulans.
PubMed:Antioxidant and Hepatoprotective Effects of Naringenin and Its β-Cyclodextrin Formulation in Mice Intoxicated with Carbon Tetrachloride: A Comparative Study.
PubMed:Mild and novel electrochemical preparation of β-cyclodextrin/graphene nanocomposite film for super-sensitive sensing of quercetin.
PubMed:2-Hydroxypropyl-β-cyclodextrin promotes transcription factor EB-mediated activation of autophagy: implications for therapy.
PubMed:Curcumin-β-cyclodextrin inclusion complex: stability, solubility, characterisation by FT-IR, FT-Raman, X-ray diffraction and photoacoustic spectroscopy, and food application.
PubMed:Association of bi-functional activity in the N-terminal domain of glycogen debranching enzyme.
PubMed:Characterization of an inclusion complex of ethyl benzoate with hydroxypropyl-β-cyclodextrin.
PubMed:Optimization of debittering of soybean antioxidant hydrolysates with β-cyclodextrins using response surface methodology.
PubMed:Optimizing separation conditions of 19 polycyclic aromatic hydrocarbons by cyclodextrin-modified capillary electrophoresis and applications to edible oils.
PubMed:Conversion of exogenous cholesterol into glycoalkaloids in potato shoots, using two methods for sterol solubilisation.
PubMed:Synthesis and characterization of nano-encapsulated black pepper oleoresin using hydroxypropyl beta-cyclodextrin for antioxidant and antimicrobial applications.
PubMed:Effect of pH on the Complexation of Kaempferol-4'-glucoside with Three β-Cyclodextrin Derivatives: Isothermal Titration Calorimetry and Spectroscopy Study.
PubMed:The role of cyclodextrins in ORAC-fluorescence assays. antioxidant capacity of tyrosol and caffeic acid with hydroxypropyl-β-cyclodextrin.
PubMed:Characterizing the natural canthaxanthin/2-hydroxypropyl-β-cyclodextrin inclusion complex.
PubMed:Preparation, characterization, and thermal stability of β-cyclodextrin/soybean lecithin inclusion complex.
PubMed:Use of β-cyclodextrin and activated carbon for quantification of Salmonella enterica ser. Enteritidis from ground beef by conventional PCR without enrichment.
PubMed:Inclusion complexes of red bell pepper pigments with β-cyclodextrin: preparation, characterisation and application as natural colorant in yogurt.
PubMed:Synthesis of a thiol-β-cyclodextrin, a potential agent for controlling enzymatic browning in fruits and vegetables.
PubMed:Advances in nanomedicines for malaria treatment.
PubMed:Preparative separation of conjugated linoleic acids (CLAs) from fermented Camellia oleifera Abel cake by β-cyclodextrin (β-CD) encapsulation using pH-zone-refining countercurrent chromatography.
PubMed:A chiral ligand exchange CE system for monitoring inhibitory effect of kojic acid on tyrosinase.
PubMed:Mechanical, rheological and release behaviors of a poloxamer 407/ poloxamer 188/carbopol 940 thermosensitive composite hydrogel.
PubMed:Continuous production of β-cyclodextrin from starch by highly stable cyclodextrin glycosyltransferase immobilized on chitosan.
PubMed:Allopregnanolone as regenerative therapeutic for Alzheimer's disease: translational development and clinical promise.
PubMed:Analytical approaches to determination of carnitine in biological materials, foods and dietary supplements.
PubMed:Encapsulation of volatiles in nanofibrous polysaccharide membranes for humidity-triggered release.
PubMed:Hydroxypropyl-β-cyclodextrin impacts renal and systemic hemodynamics in the anesthetized dog.
PubMed:Separation of dietary omega-3 and omega-6 fatty acids in food by capillary electrophoresis.
PubMed:Isolation of the four methyl jasmonate stereoisomers and their effects on selected chiral volatile compounds in red raspberries.
PubMed:Use of response surface methodology to optimize the simultaneous separation of eight polycyclic aromatic hydrocarbons by capillary zone electrophoresis with laser-induced fluorescence detection.
PubMed:Physicochemical characterisation of the supramolecular structure of luteolin/cyclodextrin inclusion complex.
PubMed:A way for improving the stability of the essential oils in an environmental friendly formulation.
PubMed:Fabrication of β-cyclodextrin-coated poly (diallyldimethylammonium chloride)-functionalized graphene composite film modified glassy carbon-rotating disk electrode and its application for simultaneous electrochemical determination colorants of sunset yellow and tartrazine.
PubMed:Encapsulation and Delivery of Crystalline Hydrophobic Nutraceuticals using Nanoemulsions: Factors Affecting Polymethoxyflavone Solubility.
PubMed:Cholesterol reduction from milk using β-cyclodextrin immobilized on glass.
PubMed:Encapsulation of a flavonoid-rich Allium cepa L. var. agrogatum don extract in β-cyclodextrin for transdermal drug delivery.
PubMed:Immobilisation of β-cyclodextrin on glass: characterisation and application for cholesterol reduction from milk.
PubMed:Reversed phase High Performance Liquid Chromatography used for the physicochemical and thermodynamic characterization of piceatannol/β-cyclodextrin complex.
PubMed:Comparative study of flavor in cholesterol-removed Gouda cheese and Gouda cheese during ripening.
PubMed:Pharmacokinetics of pterostilbene in Sprague-Dawley rats: the impacts of aqueous solubility, fasting, dose escalation, and dosing route on bioavailability.
PubMed:Apoptosis of human breast cancer cells induced by microencapsulated betulinic acid from sour jujube fruits through the mitochondria transduction pathway.
PubMed:Off-flavor precursors in soy protein isolate and novel strategies for their removal.
PubMed:Cyclodextrin-mediated enantioseparation in microemulsion electrokinetic chromatography.
PubMed:Improved stability of chokeberry juice anthocyanins by β-cyclodextrin addition and refrigeration.
PubMed:Study on the intermediate ions formed by glutathione peroxidase mimic 2,2'-ditellurobis(2-deoxy-β-cyclodextrin) by electrospray ionization mass spectrometry.
PubMed:Incorporation of β-sitosterol into mitochondrial membrane enhances mitochondrial function by promoting inner mitochondrial membrane fluidity.
PubMed:Physicochemical [corrected] properties of the inclusion complex of puerarin and glucosyl-β-cyclodextrin.
PubMed:Preparation and slowly digestible properties of β-cyclodextrins (β-CDs)-modified starches.
PubMed:Empirical, thermodynamic and quantum-chemical investigations of inclusion complexation between flavanones and (2-hydroxypropyl)-cyclodextrins.
PubMed:Extraction of phenolic compounds from grapes and their pomace using β-cyclodextrin.
PubMed:Spectrofluorimetric determination of trace nitrite with o-phenylenediamine enhanced by hydroxypropyl-β-cyclodextrin.
PubMed:Formulation development and evaluation of mouth dissolving film of domperidone.
PubMed:Storage stability and antioxidant activity of complex of astaxanthin with hydroxypropyl-β-cyclodextrin.
PubMed:Determination of estrogens in pork and chicken samples by stir bar sorptive extraction combined with high-performance liquid chromatography-ultraviolet detection.
PubMed:An investigation into the supramolecular structure, solubility, stability and antioxidant activity of rutin/cyclodextrin inclusion complex.
PubMed:Enhanced mineralization of diuron using a cyclodextrin-based bioremediation technology.
PubMed:Resveratrol ameliorates high-glucose-induced hyperpermeability mediated by caveolae via VEGF/KDR pathway.
PubMed:Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells.
PubMed:Tenside-free preparation of nanogels with high functional β-cyclodextrin content.
PubMed:Preparation of the β-cyclodextrin-vitamin C (β-CD-Vc) inclusion complex under high hydrostatic pressure (HHP).
PubMed:Inclusion complex of astaxanthin with hydroxypropyl-β-cyclodextrin: UV, FTIR, 1H NMR and molecular modeling studies.
PubMed:Purification and characterization of an amylase from Opuntiaficus-indica seeds.
PubMed:Preparation of natural borneol/2-hydroxypropyl-β-cyclodextrin inclusion complex and its effect on the absorption of tetramethylpyrazine phosphate in mouse.
PubMed:Method for the determination of catechin and epicatechin enantiomers in cocoa-based ingredients and products by high-performance liquid chromatography: single-laboratory validation.
PubMed:Formation of β-cyclodextrin inclusion enhances the stability and aqueous solubility of natural borneol.
PubMed:Sorption of ochratoxin A from aqueous solutions using β-cyclodextrin-polyurethane polymer.
PubMed:Characterization of volatiles and aroma-active compounds in honeybush (Cyclopia subternata) by GC-MS and GC-O analysis.
PubMed:Effects of cyclodextrins on the flavor of goat milk and its yogurt.
PubMed:Antimicrobial activity of cyclodextrin entrapped allyl isothiocyanate in a model system and packaged fresh-cut onions.
PubMed:The major soyabean allergen P34 resists proteolysis in vitro and is transported through intestinal epithelial cells by a caveolae-mediated mechanism.
PubMed:Determination of phenylureas herbicides in food stuffs based on matrix solid-phase dispersion extraction and capillary electrophoresis with electrochemiluminescence detection.
PubMed:Single- and 14-day repeat-dose toxicity of cross-linked β-cyclodextrin in rats.
PubMed:Peptide binding to β-cyclodextrins: structure, dynamics, energetics, and electronic effects.
PubMed:Enhancing effect of hydroxypropyl-β-cyclodextrin on the intestinal absorption process of genipin.
PubMed:Development of active polyvinyl alcohol/β-cyclodextrin composites to scavenge undesirable food components.
PubMed:Testosterone as a discriminative stimulus in male rats.
PubMed:Microencapsulated antimicrobial compounds as a means to enhance electron beam irradiation treatment for inactivation of pathogens on fresh spinach leaves.
PubMed:Sensory properties of ginseng solutions modified by masking agents.
PubMed:Optimizing the use of garlic oil as antimicrobial agent on fresh-cut tomato through a controlled release system.
PubMed:Preclinical pharmacokinetic evaluation of resveratrol trimethyl ether in sprague-dawley rats: the impacts of aqueous solubility, dose escalation, food and repeated dosing on oral bioavailability.
PubMed:Studies on the supramolecular interaction between dimethomorph and disulfide linked β-cyclodextrin dimer by spectrofluorimetry and its analytical application.
PubMed:The effect of cyclodextrins on the ethanol tolerance of microorganisms suggests potential application.
PubMed:Evaluation of cholesterol depletion as a marker of nephrotoxicity in vitro for novel β-cyclodextrin derivatives.
PubMed:Interaction of curcumin and bixin with β-cyclodextrin: complexation methods, stability, and applications in food.
PubMed:Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains.
PubMed:Formation of acrylamide from glucans and asparagine.
PubMed:Quantification of trans-3,4,5,4'-Tetramethoxystilbene in rat plasma by HPLC: application to pharmacokinetic study.
PubMed:Platinum nanoparticles and their cellular uptake and DNA platination at non-cytotoxic concentrations.
PubMed:Enhancement of plant essential oils' aqueous solubility and stability using alpha and beta cyclodextrin.
PubMed:Assessment of hydroxypropyl methylcellulose, propylene glycol, polysorbate 80, and hydroxypropyl-β-cyclodextrin for use in developmental and reproductive toxicology studies.
PubMed:β-cyclodextrin and caffeine complexes with natural polyphenols from olive and olive oils: NMR, thermodynamic, and molecular modeling studies.
PubMed:Development of capillary electrophoresis fingerprint for quality control of rhizoma Smilacis Glabrae.
PubMed:Risperidone solid dispersion for orally disintegrating tablet: its formulation design and non-destructive methods of evaluation.
PubMed:Effects of central administration of distinct fatty acids on hypothalamic neuropeptide expression and energy metabolism.
PubMed:Host-guest system of nimbin and beta-cyclodextrin or its derivatives: preparation, characterization, inclusion mode, and solubilization.
PubMed:Controlled release of α-tocopherol, quercetin, and their cyclodextrin inclusion complexes from linear low-density polyethylene (LLDPE) films into a coconut oil model food system.
PubMed:Determination of L-tyrosine by beta-cyclodextrin sensitized fluorescence quenching method.
PubMed:Preparation and physicochemical properties of the complex of naringenin with hydroxypropyl-beta-cyclodextrin.
PubMed:Comprehensive investigation of hydroxypropyl methylcellulose, propylene glycol, polysorbate 80, and hydroxypropyl-beta-cyclodextrin for use in general toxicology studies.
PubMed:Comparison of chiral electrophoretic separation methods for phenethylamines and application on impurity analysis.
PubMed:Beta-cyclodextrin/surface plasmon resonance detection system for sensing bitter-astringent taste intensity of green tea catechins.
PubMed:Use of reversed phase high pressure liquid chromatography for the physicochemical and thermodynamic characterization of oxyresveratrol/beta-cyclodextrin complexes.
PubMed:Preparation of passion fruit-typical 2-alkyl ester enantiomers via lipase-catalyzed kinetic resolution.
PubMed:Interaction between amylose and beta-cyclodextrin investigated by complexing with conjugated linoleic acid.
PubMed:Preparation and physicochemical characterization of amoxicillin beta-cyclodextrin complexes.
PubMed:Enantioselective analysis of chiral anteiso fatty acids in the polar and neutral lipids of food.
PubMed:Release characteristics of freeze-dried eugenol encapsulated with beta-cyclodextrin by molecular inclusion method.
PubMed:Effect of Complexation Cyclodextrins with Phenolic Acids and Coenzyme Q10 on their Physico-Chemical Properties and Bioavailability.
PubMed:In vitro intestinal absorption of carotenoids delivered as molecular inclusion complexes with beta-cyclodextrin is not inhibited by high-density lipoproteins.
PubMed:Structure and absolute configuration of an unsaturated anteiso fatty acid from Bacillus megaterium.
PubMed:Bioavailability of xenobiotics in the soil environment.
PubMed:Fertilizability, developmental competence, and chromosomal integrity of oocytes microinjected with pre-treated spermatozoa in mice.
PubMed:Mutations of Lysine 47 in cyclodextrin glycosyltransferase from Paenibacillus macerans enhance beta-cyclodextrin specificity.
PubMed:Fractionation of polycyclic aromatic hydrocarbon residues in soils.
PubMed:Inclusion complex of butachlor with beta-cyclodextrin: characterization, solubility, and speciation-dependent adsorption.
PubMed:Delivery of bioactive conjugated linoleic acid with self-assembled amylose-CLA complex.
PubMed:Role of maltogenic amylase and pullulanase in maltodextrin and glycogen metabolism of Bacillus subtilis 168.
PubMed:Mechanistic approach by which polysaccharides inhibit α-amylase/procyanidin aggregation.
PubMed:Detection of carbendazim by surface-enhanced Raman scattering using cyclodextrin inclusion complexes on gold nanorods.
PubMed:Development of a dual-analyte fluorescent sensor for the determination of bioactive nitrite and selenite in water samples.
PubMed:Use of beta-cyclodextrin to decrease the level of cholesterol in milk fat.
PubMed:The accelerated ripening of cholesterol-reduced Cheddar cheese by crosslinked beta-cyclodextrin.
PubMed:Analysis of flavonoids in propolis and Ginkgo biloba by micellar electrokinetic capillary chromatography.
PubMed:Quantification of salsolinol enantiomers by stable isotope dilution liquid chromatography with tandem mass spectrometric detection.
PubMed:Characterization of a novel debranching enzyme from Nostoc punctiforme possessing a high specificity for long branched chains.
PubMed:Separation and determination of l-tyrosine and its metabolites by capillary zone electrophoresis with a wall-jet amperometric detection.
PubMed:Cyclodextrin enhanced spectrofluorimetric determination of fluoxetine in pharmaceuticals and biological fluids.
PubMed:Spectrofluorimetric study of the beta-cyclodextrin:vitamin K3 complex and determination of vitamin K3.
PubMed:Adsorbed resin phase spectrophotometric determination of vanillin or/and its derivatives.
PubMed:Differences in lipogenesis and lipolysis in obese and non-obese adult human adipocytes.
PubMed:Thermal stability of anthocyanin extract of Hibiscus sabdariffa L. in the presence of beta-cyclodextrin.
PubMed:Beta-cyclodextrins as carriers of monoterpenes into the hemolymph of the honey bee (Apis mellifera) for integrated pest management.
PubMed:Relative bioavailability of two forms of a novel water-soluble coenzyme Q10.
PubMed:Characterization of cyclodextrin glucanotransferase produced by Bacillus megaterium.
PubMed:Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography.
PubMed:Preparation, stabilization, and bioefficacy of beta-cyclodextrin inclusion compounds of chloramidophos.
PubMed:Cyclodextrins.
PubMed:Distribution and organoleptic impact of sotolon enantiomers in dry white wines.
PubMed:Encapsulation of nutraceutical monoterpenes in beta-cyclodextrin and modified starch.
PubMed:Development of an innovative soil remediation: "Cyclodextrin-enhanced combined technology".
PubMed:Extracellular secretion of a maltogenic amylase from Lactobacillus gasseri ATCC33323 in Lactococcus lactis MG1363 and its application on the production of branched maltooligosaccharides.
PubMed:Enzymatic synthesis of dimaltosyl-beta-cyclodextrin via a transglycosylation reaction using TreX, a Sulfolobus solfataricus P2 debranching enzyme.
PubMed:Cloning and characterization of glycogen-debranching enzyme from hyperthermophilic archaeon Sulfolobus shibatae.
PubMed:Enantioselective analysis of secondary alcohols and their esters in purple and yellow passion fruits.
PubMed:Preferential efflux of phytosterols over cholesterol from macrophages.
PubMed:Kinetic study of the activation of banana juice enzymatic browning by the addition of maltosyl-beta-cyclodextrin.
PubMed:Cyclodextrin enhanced biodegradation of polycyclic aromatic hydrocarbons and phenols in contaminated soil slurries.
PubMed:Encapsulation of olive leaf extract in beta-cyclodextrin.
PubMed:Enantioselective separation of all-E-astaxanthin and its determination in microbial sources.
PubMed:A new technique to prevent the main post harvest diseases in berries during storage: inclusion complexes beta-cyclodextrin-hexanal.
PubMed:Pharmacokinetics of itraconazole after intravenous and oral dosing of itraconazole-cyclodextrin formulations.
PubMed:Direct and rapid discrimination of aflatoxigenic strains based on fibre-optic room temperature phosphorescence detection.
PubMed:Linear solvation energy correlation of the solvatochromic response of amino acid functionalized chromophores.
PubMed:Enantioselective determination of anteiso fatty acids in food samples.
PubMed:Complexation study of brilliant cresyl blue with beta-cyclodextrin and its derivatives by UV-vis and fluorospectrometry.
PubMed:Preparation and characterization of inclusion complex of iprodione and beta-cyclodextrin to improve fungicidal activity.
PubMed:The use of fetal bovine serum as delivery vehicle to improve the uptake and stability of lycopene in cell culture studies.
PubMed:Preparation and study on the solid inclusion complex of cloxacillin sodium with beta-cyclodextrin.
PubMed:Simultaneous mobilization of heavy metals and polychlorinated biphenyl (PCB) compounds from soil with cyclodextrin and EDTA in admixture.
PubMed:Study of a room temperature phosphorescence phenomenon to allow the detection of aflatoxigenic strains in culture media.
PubMed:Properties of cholesterol-reduced butter made with beta-cyclodextrin and added evening primrose oil and phytosterols.
PubMed:Sodium cromoglycate inhibits absorption of the major soybean allergen, Gly m Bd 30K, in mice and human intestinal Caco-2 cells.
PubMed:Dimerization of CXCR4 in living malignant cells: control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions.
PubMed:Release of alpha-tocopherol from antioxidative low-density polyethylene film into fatty food simulant: influence of complexation in beta-cyclodextrin.
PubMed:Effect of the simultaneous addition of beta-cyclodextrin and the herbicide norflurazon on its adsorption and movement in soils.
PubMed:Cyclodextrin (CD) complexes of cholesterol--their potential use in reducing dietary cholesterol intake.
PubMed:Use of a complexation of tebuconazole with beta-cyclodextrin for controlling foot and crown rot of durum wheat incited by Fusarium culmorum.
PubMed:Study on the supramolecular interaction of thiabendazole and beta-cyclodextrin by spectrophotometry and its analytical application.
PubMed:Development of fast-dissolving tablets of flurbiprofen-cyclodextrin complexes.
PubMed:Fluorescence resonance energy transfer (FRET) microscopy in living cells as a novel tool for the study of cytokine action.
PubMed:Stable polymeric microballoons as multifunctional device for biomedical uses: synthesis and characterization.
PubMed:Enantioselective determination of chiral toxaphene congeners in laying hens and eggs using multidimensional high-resolution gas chromatography.
PubMed:Environmental effects of inclusion complexation between methylated beta-cyclodextrin and diclofop-methyl.
PubMed:Characterization of cyclodextrin glycosyltransferase of the same gene expressed from Bacillus macerans, Bacillus subtilis, and Escherichia coli.
PubMed:2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD): a toxicology review.
PubMed:Chiral comprehensive two-dimensional gas chromatography with electron-capture detection applied to the analysis of chiral polychlorinated biphenyls in food samples.
PubMed:Improvement of the desorption of the herbicide norflurazon from soils via complexation with beta-cyclodextrin.
PubMed:Highly sensitive and selective room-temperature phosphorescence determination of thiabendazole by the supramolecular interaction of thiabendazole/beta-cyclodextrin/triton X-100.
PubMed:Development and validation of a separation method for the diastereomers and enantiomers of aziridine-type protease inhibitors.
PubMed:Effect of beta-cyclodextrin in improving the correlation between lycopene concentration and ORAC values.
PubMed:Long-term shelf stability of amphiphilic beta-cyclodextrin nanosphere suspensions monitored by dynamic light scattering and cryo-transmission electron microscopy.
PubMed:Chiral capillary electrophoresis-mass spectrometry of amino acids in foods.
PubMed:Enantiomeric separation of chiral polychlorinated biphenyls on beta-cyclodextrin capillary columns by means of heart-cut multidimensional gas chromatography and comprehensive two-dimensional gas chromatography. Application to food samples.
PubMed:Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug.
PubMed:Sulfluramid volatility reduction by beta-cyclodextrin.
PubMed:Crosslinking of beta-cyclodextrin on cholesterol removal from milk.
PubMed:Enzymatic analysis of an amylolytic enzyme from the hyperthermophilic archaeon Pyrococcus furiosus reveals its novel catalytic properties as both an alpha-amylase and a cyclodextrin-hydrolyzing enzyme.
PubMed:Immobilized beta-cyclodextrin as a simple and recyclable method for cholesterol removal in milk.
PubMed:Separation of flavanone-7-O-glycoside diastereomers and analysis in citrus juices by multidimensional liquid chromatography coupled with mass spectrometry.
PubMed:Determination of binding constants of cyclodextrin inclusion complexes with amino acids and dipeptides by potentiometric titration.
PubMed:Effect of beta-cyclodextrin on aroma release and flavor perception.
PubMed:Structural characterization of imazalil/beta-cyclodextrin inclusion complex.
PubMed:Separation of purine and pyrimidine bases by capillary electrophoresis using beta-cyclodextrin as an additive.
PubMed:Preparation and characterization of inclusion complex of norflurazon and beta-cyclodextrin to improve herbicide formulations.
PubMed:Separation and analysis of diastereomers and enantiomers of cypermethrin and cyfluthrin by gas chromatography.
PubMed:Determination of enantiomers of synthetic pyrethroids in water by solid phase microextraction - enantioselective gas chromatography.
PubMed:Stability of natamycin and its cyclodextrin inclusion complexes in aqueous solution.
PubMed:Enantioselective analysis of methyl-branched alcohols and acids in rhubarb (Rheum rhabarbarum L.) stalks.
PubMed:Enantioseparation of imazalil residue in orange by capillary electrophoresis with 2-hydroxypropyl-beta-cyclodextrin as a chiral selector.
PubMed:Functional properties of cholesterol-removed whipping cream treated by beta-cyclodextrin.
PubMed:A new micellar electrokinetic capillary chromatography method for separation of the components of the aminoglycoside antibiotics.
PubMed:Complexation of several fungicides with beta-cyclodextrin: determination of the association constants and isolation of the solid complexes.
PubMed:Kinetics of inhibition of polyphenol oxidase mediated browning in apple juice by beta-cyclodextrin and L-ascorbate-2-triphosphate.
PubMed:Development of a method for direct visual determination of aflatoxin production by colonies of the Aspergillus flavus group.
PubMed:Coupled column chromatography for separation and determination of enantiomers of phenylcarbamic acid derivatives in serum.
PubMed:Biogenetic studies in Syringa vulgaris L.: synthesis and bioconversion of deuterium-labeled precursors into lilac aldehydes and lilac alcohols.
PubMed:Removal of cholesterol from Cheddar cheese by beta-cyclodextrin.
PubMed:Complexation of imazalil with beta-cyclodextrin, residue uptake, persistence, and activity against penicillium decay in citrus fruit following postharvest dip treatments.
PubMed:The self-association of the drug acemetacin and its interactions and stabilization with beta-cyclodextrin in aqueous solution as inferred from NMR spectroscopy and HPLC studies.
PubMed:Liquid chromatographic determination of alcohols in food and beverages with indirect polarimetric detection using a beta-cyclodextrin mobile phase.
PubMed:Determining eight colorants in milk beverages by capillary electrophoresis.
PubMed:Selective fluorescent molecular sensing based on 2A,2D-disulfonyl dibenzosulfolane-diphenyl-capped beta-cyclodextrin for phenolic guests.
PubMed:Evaluation of the impurity profile of alcuronium by means of capillary electrophoresis.
PubMed:Inclusion complex of conjugated linoleic acid (CLA) with cyclodextrins.
PubMed:Development and validation of oxygen radical absorbance capacity assay for lipophilic antioxidants using randomly methylated beta-cyclodextrin as the solubility enhancer.
PubMed:Monte Carlo docking simulations of cyclomaltoheptaose and dimethyl cyclomaltoheptaose with paclitaxel.
PubMed:Study on the supramolecular interaction of curcumin and beta-cyclodextrin by spectrophotometry and its analytical application.
PubMed:Improved amperometric method for the rapid and quantitative measurement of lipoxygenase activity in vegetable tissue crude homogenates.
PubMed:Catalytic activities of intracellular dimeric neopullulanase on cyclodextrin, acarbose and maltose.
PubMed:Behaviors of D- and L-lactic acids during the brewing process of sake (Japanese rice wine).
PubMed:Cross-linked beta-cyclodextrin microcapsules. II. Retarding effect on drug release through semi-permeable membranes.
PubMed:The solid-state stability of amorphous quinapril in the presence of beta-cyclodextrins.
PubMed:New reversed-phase liquid chromatographic method to detect aflatoxins in food and feed with cyclodextrins as fluorescence enhancers added to the eluent.
PubMed:Interpreting nonracemic ratios of chiral organochlorines using naturally contaminated fish.
PubMed:Do we know the mechanism of chiral recognition between cyclodextrins and analytes?
PubMed:Complexation of several benzimidazole-type fungicides with alpha- and beta-cyclodextrins.
PubMed:Synthesis and analysis of thio-, thiono-, and dithio-derivatives of whiskey lactone.
PubMed:Competitive binding of aroma compounds by beta-cyclodextrin.
PubMed:Modulation of the multisubstrate specificity of Thermus maltogenic amylase by truncation of the N-terminal domain and by a salt-induced shift of the monomer/dimer equilibrium.
PubMed:Enantioseparation of chiral thiobarbiturates using cyclodextrin-modified capillary electrophoresis.
PubMed:Derivatization, stabilization and detection of biogenic amines by cyclodextrin-modified capillary electrophoresis-laser-induced fluorescence detection.
PubMed:Elucidation of solution state complexation in wet-granulated oven-dried ibuprofen and beta-cyclodextrin: FT-IR and 1H-NMR studies.
PubMed:Enhancement of ibuprofen dissolution via wet granulation with beta-cyclodextrin.
PubMed:[Food additives: effects on pregnancy and lactation].
PubMed:General approach to the synthesis of persubstituted hydrophilic and amphiphilic beta-cyclodextrin derivatives.
PubMed:Study on the chiral recognition of the enantiomers of ephedrine derivatives with neutral and sulfated heptakis(2,3-O-diacetyl)-beta-cyclodextrins using capillary electrophoresis, UV, nuclear magnetic resonance spectroscopy and mass spectrometry.
PubMed:Stereochemical composition of clenbuterol residues in edible tissues of swine.
PubMed:Structure, dynamics, and stability of beta-cyclodextrin inclusion complexes of aspartame and neotame.
PubMed:Determination of RS,E/Z-tocotrienols by HPLC.
PubMed:Analytical and Sensory Characterization of gamma- and delta-Thiolactones.
PubMed:Liposomes containing drug and cyclodextrin prepared by the one-step spray-drying method.
PubMed:Direct compression tablets containing a series of four beta-cyclodextrin complexes formed by neutralizing an acidic drug.
PubMed:Cross-linked beta-cyclodextrin microcapsules: preparation and properties.
PubMed:Interaction of 6-p-toluidinylnaphthalene-2-sulphonate with beta-cyclodextrin.
PubMed:Comparative population pharmacokinetic-pharmacodynamic analysis for piroxicam-beta-cyclodextrin and piroxicam.
PubMed:Nimesulide and beta-cyclodextrin inclusion complexes: physicochemical characterization and dissolution rate studies.
PubMed:The influence of diluent on the release of theophylline from hydrophilic matrix tablets.
PubMed:Release characteristics of a short-chain fatty acid, n-butyric acid, from its beta-cyclodextrin ester conjugate in rat biological media.
PubMed:Determination of fumaric acid in apple juice by on-line coupled capillary isotachophoresis-capillary zone electrophoresis with UV detection.
PubMed:Study of interaction phenomena between aroma compounds and carbohydrate matrixes by inverse gas chromatography.
PubMed:Direct chiral resolution of lactic acid in food products by capillary electrophoresis.
PubMed:Enantioselective determination of persistent and partly degradable toxaphene congeners in high trophic level biota.
PubMed:Stereodifferentiation of 3-hydroxyisobutyric- and 3-aminoisobutyric acid in human urine by enantioselective multidimensional capillary gas chromatography-mass spectrometry.
PubMed:Pharmacokinetics of SCH 56592, a new azole broad-spectrum antifungal agent, in mice, rats, rabbits, dogs, and cynomolgus monkeys.
PubMed:Encapsulation of lemon oil by paste method using beta-cyclodextrin: encapsulation efficiency and profile of oil volatiles.
PubMed:Stabilization of the avicide 3-chloro-p-toluidine as the beta-cyclodextrin adduct.
PubMed:Cyclodextrin-based optosensor for the determination of warfarin in waters.
PubMed:Cholesterol removal from homogenized milk with beta-cyclodextrin.
PubMed:Quantification of racemization of amino acids in alkaline-treated duck eggs by micellar capillary electrophoresis.
PubMed:Poly(acrylic acid) microspheres containing beta-cyclodextrin: loading and in vitro release of two dyes.
PubMed:Modes of action of acarbose hydrolysis and transglycosylation catalyzed by a thermostable maltogenic amylase, the gene for which was cloned from a Thermus strain.
PubMed:Impact of beta-cyclodextrin and resistant starch on bile acid metabolism and fecal steroid excretion in regard to their hypolipidemic action in hamsters.
PubMed:Preparation and characterization of beta-cyclodextrin and poly(acrylic acid) microspheres.
PubMed:Crystal structure of recombinant soybean beta-amylase complexed with beta-cyclodextrin.
PubMed:Reduction of the suppressive effects of gurmarin on sweet taste responses by addition of beta-cyclodextrin.
PubMed:beta-Cyclodextrin production by simultaneous fermentation and cyclization.
PubMed:Molecular and enzymatic characterization of a maltogenic amylase that hydrolyzes and transglycosylates acarbose.
PubMed:Food interaction and steady-state pharmacokinetics of itraconazole oral solution in healthy volunteers.
PubMed:Novel non-acidic formulations of haloperidol complexed with beta-cyclodextrin derivatives.
PubMed:Use of cyclodextrin to deliver lipids and to modulate apolipoprotein B-100 production in HepG2 cells.
PubMed:Acetylation of or beta-cyclodextrin addition to potato beneficial effect on glucose metabolism and appetite sensations.
PubMed:Solution structure of the granular starch binding domain of Aspergillus niger glucoamylase bound to beta-cyclodextrin.
PubMed:Composition and functional properties of cholesterol reduced egg yolk.
PubMed:Carcinogenicity study of beta-cyclodextrin in F344 rats.
PubMed:Inducing cholesterol precipitation from pig bile with beta-cyclodextrin and cholesterol dietary supplementation.
PubMed:Assay for the (R)- and (S)-enantiomers of salsolinols in biological samples and foods with ion-pair high-performance liquid chromatography using beta-cyclodextrin as a chiral mobile phase additive.
PubMed:Penicillin Acylase-Mediated Synthesis of 2-Acetyl-1-pyrroline and of 2-Propionyl-1-pyrroline, Key Roast-Smelling Odorants in Food. Inclusion Complexes with beta-Cyclodextrin and Their NMR and MS Characterization.
PubMed:Derivative spectrophotometric resolution of mixtures of the food colourants Tartrazine, Amaranth and Curcumin in a micellar medium.
PubMed:Effect of food on the pharmacokinetics of a new hydroxypropyl-beta-cyclodextrin formulation of itraconazole.
PubMed:Effects of SKF 108922, an HIV-1 protease inhibitor, on retrovirus replication in mice.
PubMed:Synthetic pyridopurines derived from food pyrolysis products: intercalation, interactions with membranes, cyclodextrin complexation, and biological mitogenic properties.
PubMed:Postcolumn excitation of aflatoxins using cyclodextrins in liquid chromatography for food analysis.
PubMed:Hydroxypropyl cyclodextrins: potential synergism with carcinogens.
PubMed:Determination of ephedrine compounds in nutritional supplements by cyclodextrin-modified capillary electrophoresis.
PubMed:The reproductive and developmental toxicity profile of beta-cyclodextrin in rodents.
PubMed:Differential scanning calorimetric studies on the domain structure of Aspergillus glucoamylase.
PubMed:beta-Cyclodextrin: 52-week toxicity studies in the rat and dog.
PubMed:Effect of temperature on separation of estradiol stereoisomers and equilin by liquid chromatography using mobile phases modified with beta-cyclodextrin.
PubMed:Use of principal component analysis for the evaluation of the retention behaviour of monoamine oxidase inhibitory drugs on beta-cyclodextrin column.
PubMed:Evaluation of certain food additives and contaminants.
PubMed:[Hepatic lesions in F344 rats treated orally with beta-cyclodextrin for 13 weeks].
PubMed:Investigation of potential oncogenetic effects of beta-cyclodextrin in the rat and mouse.
PubMed:A stable water-soluble tetramethylbenzidine-2-hydroxypropyl-beta-cyclodextrin inclusion complex and its applications in enzyme assays.
PubMed:Comparison of the binding of beta-cyclodextrin and alpha- and gamma-cyclodextrins with pullulanase from Klebsiella pneumoniae as studied by equilibrium and kinetic fluorometry.
PubMed:Determination of synthetic food dyes by capillary electrophoresis.
PubMed:Chemical profiling of pharmaceuticals by capillary electrophoresis in the determination of drug origin.
PubMed:Neutral and anionic cyclodextrins in capillary zone electrophoresis: enantiomeric separation of ephedrine and related compounds.
PubMed:Starch-binding domain of Aspergillus glucoamylase-I. Interaction with beta-cyclodextrin and maltoheptaose.
PubMed:Safety of oral cyclodextrins: effects of hydroxypropyl cyclodextrins, cyclodextrin sulfates and cationic cyclodextrins on steroid balance in rats.
PubMed:Evaluation of piroxicam-beta-cyclodextrin, piroxicam, paracetamol and placebo in post-operative oral surgery pain.
PubMed:Evidence for beta-galactosidase catalyzed hydrolysis of paranitrophenyl-beta-D-galactopyranoside anchored in cyclodextrins.
PubMed:Fate of beta-cyclodextrin in the human intestine.
PubMed:Interaction between pullulanase from Klebsiella pneumoniae and cyclodextrins.
PubMed:Supermolecular inclusion of piroxicam with beta-cyclodextrin: pharmacokinetic properties in man.
PubMed:O-glycosylation and stability. Unfolding of glucoamylase induced by heat and guanidine hydrochloride.
PubMed:O-glycosylation in Aspergillus glucoamylase. Conformation and role in binding.
PubMed:Binding of Cu(2+)-beta-cyclodextrin complex to calf thymus DNA.
PubMed:Interaction of beta-cyclodextrin with the granular starch binding domain of glucoamylase.
PubMed:Soybean lipoxygenase catalysed oxygenation of unsaturated fatty acid encapsulated in cyclodextrin.
PubMed:Beta-cyclodextrin post-column fluorescence enhancement of aflatoxins for reverse-phase liquid chromatographic determination in corn.
 
Notes:
GRAS status for use as a flavour carrier or protectant in food
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