EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

1,2,6-hexane triol
1,2,6-trihydroxyhexane

Supplier Sponsors

Name:hexane-1,2,6-triol
CAS Number: 106-69-4Picture of molecule3D/inchi
Other(deleted CASRN):112254-74-7
ECHA EINECS - REACH Pre-Reg:203-424-6
FDA UNII: W45XXM0XWE
Nikkaji Web:J35.168G
Beilstein Number:1304479
MDL:MFCD00002976
XlogP3-AA:0.70 (est)
Molecular Weight:134.17518000
Formula:C6 H14 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.10200 to 1.10500 @ 20.00 °C.
Pounds per Gallon - (est).: 9.180 to 9.205
Refractive Index:1.47400 to 1.47800 @ 20.00 °C.
Melting Point: -20.00 °C. @ 760.00 mm Hg
Boiling Point: 178.00 °C. @ 5.00 mm Hg
Boiling Point: 166.00 to 168.00 °C. @ 2.00 mm Hg
Vapor Pressure:0.000021 mmHg @ 25.00 °C. (est)
Vapor Density:4.63 ( Air = 1 )
Flash Point: 175.00 °F. TCC ( 79.44 °C. )
logP (o/w): -1.386 (est)
Soluble in:
 alcohol
 water, 4.05e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Taste Description: tasteless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: humectants
skin conditioning
skin conditioning - emollient
solvents
viscosity controlling agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
1,2,6-Hexanetriol 96%
Carbosynth
For experimental / research use only.
1,2,6-Hexanetriol
EMD Millipore
For experimental / research use only.
1,2,6-Hexanetriol
sds
Penta International
1,2,6-HEXANETRIOL
Santa Cruz Biotechnology
For experimental / research use only.
1,2,6-Hexanetriol
Sigma-Aldrich: Aldrich
For experimental / research use only.
1,2,6-Hexanetriol 96%
sds
TCI AMERICA
For experimental / research use only.
1,2,6-Hexanetriol >96.0%(GC)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 15500 mg/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969.

intravenous-rat LD50 5600 mg/kg
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF ENDOCRINE PANCREAS LIVER: OTHER CHANGES
Toxicology and Applied Pharmacology. Vol. 15, Pg. 282, 1969.

intraperitoneal-rat LD50 10000 mg/kg
LIVER: OTHER CHANGES GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF ENDOCRINE PANCREAS
Toxicology and Applied Pharmacology. Vol. 15, Pg. 282, 1969.

oral-mouse LD50 11400 mg/kg
Shell Chemical Company. Unpublished Report. Vol. -, Pg. 5, 1961.

Dermal Toxicity:
skin-rabbit LD50 > 20 ml/kg
Union Carbide Data Sheet. Vol. 7/13/1971

subcutaneous-rat LD50 10900 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 28, Pg. 276, 1972.

subcutaneous-mouse LD50 5800 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 28, Pg. 276, 1972.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic agents
Recommendation for 1,2,6-hexane triol usage levels up to:
 not for fragrance use.
 
Recommendation for 1,2,6-hexane triol flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):106-69-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :7823
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
hexane-1,2,6-triol
Chemidplus:0000106694
RTECS:MO4650000 for cas# 106-69-4
 
References:
 hexane-1,2,6-triol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):7823
Pubchem (sid):134971925
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
KEGG (GenomeNet):C20334
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2905.49.1000
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 humectants
 solvents
 viscosity controlling agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
1,2,6-hexane triol
 hexane-1,2,6-triol
1,2,6-hexanetriol
 hexanetriol-1,2,6
1,2,6-trihydroxyhexane
 

Articles:

PubMed:Deviations from plane-wave Mie scattering and precise retrieval of refractive index for a single spherical particle in an optical cavity.
PubMed:Measurements of the evaporation and hygroscopic response of single fine-mode aerosol particles using a Bessel beam optical trap.
PubMed:Surface-enhanced Raman spectroscopy detection of polybrominated diphenylethers using a portable Raman spectrometer.
PubMed:Impact of organic coating on optical growth of ammonium sulfate particles.
PubMed:Communication: Two measures of isochronal superposition.
PubMed:Solid-support immobilization of a "swing" fusion protein for enhanced glucose oxidase catalytic activity.
PubMed:Enhanced stability of Janus nanoparticles by covalent cross-linking of surface ligands.
PubMed:Poly(meth)acrylates obtained by cascade reaction.
PubMed:Thermal glycosylation and degradation reactions occurring at the reducing ends of cellulose during low-temperature pyrolysis.
PubMed:Dynamics and structure of hydrogen-bonding glass formers: comparison between hexanetriol and sugar alcohols based on dielectric relaxation.
PubMed:Microfluidic etching and oxime-based tailoring of biodegradable polyketoesters.
PubMed:Time and pH dependent colon specific, pulsatile delivery of theophylline for nocturnal asthma.
PubMed:Stereoselective oxidation of aliphatic diols and reduction of hydroxy-ketones with galactitol dehydrogenase from Rhodobacter sphaeroides D.
PubMed:Chiral direction and interconnection of helical three-connected networks in metal-organic frameworks.
PubMed:Improved method for quantifying levoglucosan and related monosaccharide anhydrides in atmospheric aerosols and application to samples from urban and tropical locations.
PubMed:Allergic contact dermatitis from 1,2,6-hexanetriol in fluocinonide cream.
PubMed:Hydrogels of poly(ethylene glycol): mechanical characterization and release of a model drug.
PubMed:Development of a drug delivery system for the treatment of periodontal disease based on bioerodible poly(ortho esters).
PubMed:Experimental toxicity and metabolism of 1,2,6-hexanetriol.
PubMed:[1,2,6-Hexanetriol, a new substance in preparation of water soluble ointment bases].
 
Notes:
None found
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