disodium 5'-inosinate
disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate

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  4691-65-0 Disodium 5'-inosinate

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  MP-001776 IMP-INOSINE 5'-DISODIUM PHOSPHATE

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  I0036 Inosine 5'-Monophosphate Disodium Salt Hydrate >98.0%(HPLC)(E)
  SDS

Name: disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate CAS Number: 4691-65-0 3D/inchi ECHA EINECS - REACH Pre-Reg: 225-146-4 FDA UNII: T2ZYA7KC05 MDL: MFCD00150372 CoE Number: 11895 Molecular Weight: 392.17257056 Formula: C10 H11 N4 Na2 O8 P BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:flavor enhancers   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search JECFA Food Additive: Disodium 5'-Inosinate GSFA Codex: Disodium 5'-inosinate (631) DG SANTE Food Additives: disodium inosinate FEMA Number: 3669 disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate FDA: No longer provide for the use of these seven synthetic flavoring substances FDA Mainterm (SATF): 4691-65-0 ; DISODIUM INOSINATE FDA Regulation: FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.120 Canned green beans and canned wax beans. FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.130 Canned corn. FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.170 Canned peas. FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.200 Certain other canned vegetables. FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.201 Canned mushrooms. FDA PART 170 -- FOOD ADDITIVES Subpart C--Specific Administrative Rulings and Decisions Sec. 170.60 Nitrites and/or nitrates in curing premixes. FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart F--Flavoring Agents and Related Substances Sec. 172.535 Disodium inosinate.   Physical Properties: Appearance: white crystalline powder (est) Assay: 97.00 to 100.00 Food Chemicals Codex Listed: No Boiling Point: 851.40 °C. @ 760.00 mm Hg (est) Flash Point: 876.00 °F. TCC ( 468.70 °C. ) (est) logP (o/w): -1.023 (est) Soluble in:   water, 1e+006 mg/L @ 25 °C (est)   alcohol, slightly Insoluble in:   ether   Organoleptic Properties: Odor Description:at 100.00 %. odorless Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: humectants skin conditioning skin conditioning - emollient   Suppliers: Ajinomoto USA Ajitide™ Nucleotides Flavor: characteristic A premium line of nucleotides with the Ajinomoto touch which unlocks the taste characteristics of foods synergy with glutamates and other flavor enhancers nucleotides have. BOC Sciences For experimental / research use only. Disodium 5'-inosinate Carbosynth For experimental / research use only. Inosine 5'-monophosphate disodium salt hydrate ECSA Chemicals IMP-INOSINE 5'-DISODIUM PHOSPHATE ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY Kraft Chemical I + G Penta International DISODIUM-5-INOSINATE Prinova Disodium Inosinate Santa Cruz Biotechnology For experimental / research use only. Inosine 5'-monophosphate disodium salt hydrate Sigma-Aldrich: Sigma For experimental / research use only. Inosine 5'-monophosphate disodium salt from muscle, Sigma Grade, 99-100% sds Sinofi Food Ingredients Disodium Inosinate (E631 Flavor Enhancer) Flavor: characteristic Flavour Enhancer, Instant Noodle, Pizza, Cheese, Snack Foods, Potato Chip, Crackers, Sauces, Fast Food, Baking Food, Ice Cream, Canned Food, Meats, Poultry, Sauces, Soups, Soft Candy, Puddings, Condiments, Snack Food, Fish, Seasonings. TCI AMERICA For experimental / research use only. Inosine 5'-Monophosphate Disodium Salt Hydrate >98.0%(HPLC)(E) sds   Safety Information: Preferred SDS: View European information : Most important hazard(s): None - None found. R 02 - Risk of explosion by shock, friction, fire or other sources of ignition. R 23/24 - Toxic by inhalation and in contact with skin.   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: intraperitoneal-rat LD50 4850 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. oral-mouse LD50 12000 mg/kg Tokyo Ika Daigaku Zasshi. Journal of Tokyo Medical College. Vol. 24, Pg. 553, 1966. intravenous-mouse LD50 3300 mg/kg Tokyo Ika Daigaku Zasshi. Journal of Tokyo Medical College. Vol. 24, Pg. 553, 1966. intraperitoneal-mouse LD50 5400 mg/kg Tokyo Ika Daigaku Zasshi. Journal of Tokyo Medical College. Vol. 24, Pg. 553, 1966. intravenous-rat LD50 2730 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. oral-rat LD50 15900 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. Dermal Toxicity: subcutaneous-mouse LD50 5480 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. subcutaneous-rat LD50 3900 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. Inhalation Toxicity: Not determined   Safety in Use Information: Category: flavor enhancers Recommendation for disodium 5'-inosinate usage levels up to:   not for fragrance use.   Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library publication number: 13 Click here to view publication 13   average usual ppm average maximum ppm baked goods: - 141.00000 beverages(nonalcoholic): - 220.00000 beverages(alcoholic): - - breakfast cereal: - - cheese: - 0.40000 chewing gum: - - condiments / relishes: - 3200.00000 confectionery froastings: - - egg products: - - fats / oils: - 2000.00000 fish products: - 10.00000 frozen dairy: - 3000.00000 fruit ices: - - gelatins / puddings: - - granulated sugar: - - gravies: - 660.00000 hard candy: - - imitation dairy: - - instant coffee / tea: - - jams / jellies: - - meat products: - 314.00000 milk products: - 46.00000 nut products: - - other grains: - 240.00000 poultry: - 200.00000 processed fruits: - - processed vegetables: - 220.00000 reconstituted vegetables: - 50.00000 seasonings / flavors: - 1000.00000 snack foods: - 50.00000 soft candy: - 3000.00000 soups: - 660.00000 sugar substitutes: - - sweet sauces: - -   Safety References: European Food Safety Authority (EFSA) reference(s): Scientific Opinion on the safety and efficacy of disodium 5'-ribonucleotides, disodium 5'-guanylate, disodium 5'-inosinate for all animal species and categories View page or View pdf Safety and efficacy of IMP (disodium 5'-inosinate) produced by fermentation with Corynebacterium stationis KCCM 80161 for all animal species View page or View pdf EPI System: View Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):4691-65-0 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :20819 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate Chemidplus:0004691650 RTECS:NM7519500 for cas# 4691-65-0   References:   disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 4691-65-0 Pubchem (cid): 20819 Pubchem (sid): 134984663   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View HMDB (The Human Metabolome Database): Search FooDB: FDB019972 Export Tariff Code: 2934.99.9000 FDA Listing of Food Additive Status: View ChemSpider: View Wikipedia: View EFSA Update of results on the monitoring of furan levels in food: Read Report EFSA Previous report: Results on the monitoring of furan levels in food: Read Report EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report   Potential Blenders and core components note None Found   Potential Uses:   emollients   humectants   skin conditioning   Occurrence (nature, food, other):note   not found in nature   Synonyms:   ajitide nucleotides   disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphate   disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methyl phosphate   disodium 5'-O-phosphonatoinosine   disodium 5'-ribonucleotide   disodium 9-(5-O-phosphonato-b-D-ribofuranosyl)-9H-purin-6-ol   disodium inosinate   disodium inosine 5'-monophosphate   disodium inosine 5'-phosphate   disodium inosine-5'-monophosphate   disodium-5-inosinate   disodium-5'-inosinate   IMP disodium salt 5'- imp disodium salt   IMP sodium salt 5'- IMP-Na2   Inosin-5'-monophosphate disodium   inosine 5'-monophosphate disodium   inosine 5'-monophosphate disodium salt   inosine 5'-monophosphate disodium salt hydrate   inosine 5'-monphosphate disodium salt   inosine-5'-monophosphate disodium 5'- inosinic acid, sodium salt (1:2) 9H- purin-6-ol, 9-(5-O-phosphono-b-D-ribofuranosyl)-, sodium salt (1:2)   sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)-tetrahydrofuran-2-yl)methyl phosphate   sodium 5'-inosinate   Articles:   None found yet. Try the PubMed Search.

Notes: Flavour enhancer As it is a fairly expensive additive, it usually is not used independently of glutamic acid; if disodium inosinate is present in a list of ingredients but MSG does not appear to be, it is possible that glutamic acid is provided as part of another ingredient or is naturally occurring in another ingredient like tomatoes, Parmesan cheese or yeast extract. It is often added to foods in conjunction with disodium guanylate; the combination is known as disodium 5'-ribonucleotides.; Disodium inosinate (E631), chemical formula C10H11N2Na2O8P, is the disodium salt of inosinic acid. It is a food additive often found in instant noodles, potato chips, and a variety of other snacks. It is used as a flavor enhancer, in synergy with monosodium glutamate (also known as MSG; the sodium salt of glutamic acid) to provide the umami taste. It is mainly found in animals like pigs and fish.