disodium 5'-guanylate
disodium guanylate

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  5550-12-9 Disodium 5'-guanylate 98%

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  GE5826 Guanosine 5'-monophosphate disodium salt hydrate

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  G0172 Guanosine 5'-Monophosphate Disodium Salt Hydrate >98.0%(HPLC)(N)
  SDS

Name: disodium [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate CAS Number: 5550-12-9 3D/inchi ECHA EINECS - REACH Pre-Reg: 226-914-1 FDA UNII: B768T44Q8V Beilstein Number: 3586801 MDL: MFCD00070575 CoE Number: 11772 Molecular Weight: 407.18754056 Formula: C10 H12 N5 Na2 O8 P NMR Predictor: Predict (works with chrome, Edge or firefox) Category:flavor enhancers   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search JECFA Food Additive: Disodium 5'-Guanylate GSFA Codex: Disodium 5'-guanylate (627) DG SANTE Food Additives: disodium guanylate FEMA Number: 3668 disodium 5'-guanylate FDA: No longer provide for the use of these seven synthetic flavoring substances FDA Mainterm (SATF): 5550-12-9 ; DISODIUM GUANYLATE FDA Regulation: FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.120 Canned green beans and canned wax beans. FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.130 Canned corn. FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.170 Canned peas. FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.200 Certain other canned vegetables. FDA PART 155 -- CANNED VEGETABLES Subpart B--Requirements for Specific Standardized Canned Vegetables Sec. 155.201 Canned mushrooms. FDA PART 170 -- FOOD ADDITIVES Subpart C--Specific Administrative Rulings and Decisions Sec. 170.60 Nitrites and/or nitrates in curing premixes. FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart F--Flavoring Agents and Related Substances Sec. 172.530 Disodium guanylate.   Physical Properties: Appearance: white crystalline powder (est) Assay: 99.00 to 100.00 Food Chemicals Codex Listed: No Boiling Point: 890.20 °C. @ 760.00 mm Hg (est) Flash Point: 918.00 °F. TCC ( 492.20 °C. ) (est) logP (o/w): -0.423 (est) Soluble in:   water, 1e+006 mg/L @ 25 °C (est) Insoluble in:   alcohol   ether   Organoleptic Properties: Odor Description:at 100.00 %. odorless Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: humectants skin conditioning skin conditioning - emollient   Suppliers: Ajinomoto USA Ajitide™ Nucleotides Flavor: characteristic A premium line of nucleotides with the Ajinomoto touch which unlocks the taste characteristics of foods synergy with glutamates and other flavor enhancers nucleotides have. BOC Sciences For experimental / research use only. Disodium 5'-guanylate 98% Carbosynth For experimental / research use only. Guanosine 5'-monophosphate disodium salt Changzhou Longo Chemical Guanosine 5'-monophosphate disodium salt Glentham Life Sciences Guanosine 5'-monophosphate disodium salt hydrate Penta International DISODIUM-5-GUANYLATE Prinova GMP Santa Cruz Biotechnology For experimental / research use only. Guanosine 5'-monophosphate disodium salt hydrate Sigma-Aldrich: Sigma For experimental / research use only. Guanosine 5'-monophosphate disodium salt hydrate from yeast, ≥99% sds Sinofi Food Ingredients Disodium Guanylate (E627 Flavour Enhancer) Flavor: characteristic Flavour Enhancer, Instant Noodle, Pizza, Cheese, Snack Foods, Potato Chip, Crackers, Sauces, Fast Food, Baking Food, Ice Cream, Canned Food, Meats, Poultry, Sauces, Soups, Soft Candy, Puddings, Condiments, Seasonings. TCI AMERICA For experimental / research use only. Guanosine 5'-Monophosphate Disodium Salt Hydrate >98.0%(HPLC)(N) sds   Safety Information: Preferred SDS: View European information : Most important hazard(s): None - None found. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: intraperitoneal-rat LD50 3880 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. oral-mouse LD50 15000 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LUNGS, THORAX, OR RESPIRATION: DYSPNEA Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. intravenous-mouse LD50 3580 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. intraperitoneal-mouse LD50 5010 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. intravenous-rat LD50 2720 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. oral-rat LD50 > 17300 mg/kg Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. Dermal Toxicity: subcutaneous-mouse LD50 5050 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. subcutaneous-rat LD50 3400 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Ajinomoto Co., Inc. Vol. -, Pg. -, 1973. Inhalation Toxicity: Not determined   Safety in Use Information: Category: flavor enhancers Recommendation for disodium 5'-guanylate usage levels up to:   not for fragrance use.   Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library publication number: 13 Click here to view publication 13   average usual ppm average maximum ppm baked goods: - 143.00000 beverages(nonalcoholic): - 2000.00000 beverages(alcoholic): - - breakfast cereal: - - cheese: - 0.40000 chewing gum: - - condiments / relishes: - 3200.00000 confectionery froastings: - - egg products: - - fats / oils: - 2000.00000 fish products: - 10.00000 frozen dairy: - 3000.00000 fruit ices: - - gelatins / puddings: - 2000.00000 granulated sugar: - - gravies: - 240.00000 hard candy: - - imitation dairy: - - instant coffee / tea: - - jams / jellies: - - meat products: - 200.00000 milk products: - 46.00000 nut products: - - other grains: - 240.00000 poultry: - 200.00000 processed fruits: - - processed vegetables: - 140.00000 reconstituted vegetables: - 150.00000 seasonings / flavors: - 1000.00000 snack foods: - 50.00000 soft candy: - 3000.00000 soups: - 720.00000 sugar substitutes: - - sweet sauces: - -   Safety References: European Food Safety Authority (EFSA) reference(s): Scientific Opinion on the safety and efficacy of disodium 5'-ribonucleotides, disodium 5'-guanylate, disodium 5'-inosinate for all animal species and categories View page or View pdf Safety and efficacy of a feed additive consisting of disodium 5’-guanylate produced with Corynebacterium stationis KCCM 10530 and Escherichia coli K-12 KFCC 11067 for all animal species (CJ Europe GmbH) View page or View pdf EPI System: View Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):5550-12-9 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :21712 National Institute of Allergy and Infectious Diseases:Data WGK Germany:2 disodium [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate Chemidplus:0005550129 RTECS:MF9290000 for cas# 5550-12-9   References:   disodium [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 5550-12-9 Pubchem (cid): 21712 Pubchem (sid): 134987267   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View CHEBI: View HMDB (The Human Metabolome Database): Search FooDB: FDB001167 Export Tariff Code: 2934.99.9000 FDA Listing of Food Additive Status: View ChemSpider: View Wikipedia: View EFSA Update of results on the monitoring of furan levels in food: Read Report EFSA Previous report: Results on the monitoring of furan levels in food: Read Report EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report   Potential Blenders and core components note None Found   Potential Uses:   emollients   humectants   skin conditioning   Occurrence (nature, food, other):note   not found in nature   Synonyms:   ajitide nucleotides (guanylate)   disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-imino-6-oxo-2,3,6,9-tetrahydro-1H-purin-9-yl)oxolan-2-yl]methyl phosphate   disodium [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate   disodium 2-amino-9-(5-O-phosphonato-b-D-ribofuranosyl)-9H-purin-6-ol   disodium 5'-GMP   disodium 5'-O-phosphonatoguanosine   disodium GMP   disodium guanosine 5'-monophosphate   disodium guanosine-5'-monophosphate   disodium guanylate   disodium-5-guanylate   disodium-5'-guanylate   GMP   GMP disodium salt 5'- GMP disodium salt   GMP sodium salt   guanosine 5'-(disodium phosphate)   guanosine 5'-monophosphate disodium salt   guanosine 5'-monophosphate disodium salt hydrate   guanosine 5'-monophosphate, disodium salt   guanosine 5'-phosphate disodium salt   guanosine 5'MP, disodium salt   guanosine5'-monophosphatedisodiumsalt 5- guanylic acid disodium salt   guanylic acid sodium salt 5'- guanylic acid, sodium salt (1:2) 9H- purin-6-ol, 2-amino-9-(5-O-phosphono-β-D-ribofuranosyl)-, sodium salt (1:2)   ribotide   sodium ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate   Articles:   None found yet. 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Notes: guanosine 5'-monophosphate. a guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. Flavour enhancer As it is a fairly expensive additive, it is not used independently of glutamic acid; if disodium guanylate is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient such as a processed soy protein complex. It is often added to foods in conjunction with disodium inosinate; the combination is known as disodium 5'-ribonucleotides.; Disodium guanylate (E627), also known as sodium 5'-guanylate and disodium 5'-guanylate, is the disodium salt of the flavor enhancer guanosine monophosphate (GMP). Disodium guanylate is a food additive and is commonly used in conjunction with glutamic acid (monosodium glutamate, MSG).