4-ethoxyphenol
p-ethoxyphenol

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  BOC Sciences

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  622-62-8 4-Ethoxyphenol

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  Penta International Corporation

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  08-53990 HYDROQUINONE MONOETHYL ETHER

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  Synerzine, Inc.

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  W0821 Hydroquinone Monoethyl Ether
  W0821A P-ETHOXY PHENOL

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  TCI AMERICA

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  E0216 4-Ethoxyphenol >98.0%(GC)
  SDS

Name: 4-ethoxyphenol CAS Number: 622-62-8 3D/inchi ECHA EINECS - REACH Pre-Reg: 210-748-1 FDA UNII: 605352N8AQ Nikkaji Web: J45.017K Beilstein Number: 1907114 MDL: MFCD00002334 CoE Number: 2258 XlogP3: 1.80 (est) Molecular Weight: 138.16610000 Formula: C8 H10 O2 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) EFSA/JECFA Comments: According to JECFA: Melting point is "64° (minimum)". Category:food contact closures with sealing gaskets for food containers   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search JECFA Food Flavoring: 720 hydroquinone monoethyl ether DG SANTE Food Flavourings: 04.037 4-ethoxyphenol FEMA Number: 3695 p-ethoxyphenol FDA: No longer provide for the use of these seven synthetic flavoring substances FDA Mainterm (SATF): 622-62-8 ; HYDROQUINONE MONOETHYL ETHER FDA Regulation: FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart B--Substances for Use Only as Components of Adhesives Sec. 175.105 Adhesives. FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS Subpart B--Substances for Use Only as Components of Paper and Paperboard Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use Sec. 177.2600 Rubber articles intended for repeated use.   Physical Properties: Appearance: white crystals (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Melting Point: 64.00 to 67.00 °C. @ 760.00 mm Hg Boiling Point: 246.00 to 247.00 °C. @ 760.00 mm Hg Boiling Point: 121.00 °C. @ 9.00 mm Hg Vapor Pressure: 0.017000 mmHg @ 25.00 °C. (est) Flash Point: 255.00 °F. TCC ( 123.89 °C. ) logP (o/w): 1.810 Soluble in:   alcohol   dipropylene glycol   propylene glycol   water, 9222 mg/L @ 25 °C (est) Insoluble in:   water   Organoleptic Properties: Odor Type: animal Odor Strength:low , recommend smelling in a 10.00 % solution or less Substantivity:141 hour(s) at 10.00 % in dipropylene glycol hawthorn phenolic plastic nutty Odor Description:at 10.00 % in dipropylene glycol. mild hawthorn phenolic plastic nutty Luebke, William tgsc, (2007) Odor sample from: Sigma-Aldrich Flavor Type: fruity fruity cherry cherry maraschino cherry medicinal nutty phenolic Taste Description: fruity cherry maraschino cherry medicinal nutty phenolic Luebke, William tgsc, (2007) Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: not used anymore   Suppliers: BOC Sciences For experimental / research use only. 4-Ethoxyphenol ExtraSynthese For experimental / research use only. Hydroquinone monoethylether (HPLC) ≥90% Parchem hydroquinone monoethyl ether Penta International HYDROQUINONE MONOETHYL ETHER Sigma-Aldrich: Aldrich For experimental / research use only. 4-Ethoxyphenol 99% sds Synerzine Hydroquinone Monoethyl Ether Synerzine P-ETHOXY PHENOL TCI AMERICA For experimental / research use only. 4-Ethoxyphenol >98.0%(GC) sds   Safety Information: Preferred SDS: View European information : Most important hazard(s): Xi - Irritant R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: intraperitoneal-mouse LDLo 250 mg/kg Revue Belge de Pathologie et de Medecine Experimentale. Vol. 22, Pg. 1, 1952. Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: food contact closures with sealing gaskets for food containers IFRA Critical Effect: Depigmentation   View the IFRA Standard Recommendation for 4-ethoxyphenol usage levels up to:   PROHIBITED: Should not be used as a fragrance ingredient.   Maximised Survey-derived Daily Intakes (MSDI-EU): 0.37 (μg/capita/day) Maximised Survey-derived Daily Intakes (MSDI-USA): 0.40 (μg/capita/day) Structure Class: I Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library publication number: 13 Click here to view publication 13   average usual ppm average maximum ppm baked goods: - 5.00000 beverages(nonalcoholic): - 5.00000 beverages(alcoholic): - - breakfast cereal: - - cheese: - - chewing gum: - - condiments / relishes: - - confectionery froastings: - - egg products: - - fats / oils: - - fish products: - - frozen dairy: - 5.00000 fruit ices: - - gelatins / puddings: - 5.00000 granulated sugar: - - gravies: - - hard candy: - - imitation dairy: - - instant coffee / tea: - - jams / jellies: - - meat products: - 0.50000 milk products: - - nut products: - - other grains: - - poultry: - - processed fruits: - - processed vegetables: - - reconstituted vegetables: - - seasonings / flavors: - - snack foods: - - soft candy: - 5.00000 soups: - - sugar substitutes: - - sweet sauces: - -   Safety References: European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... European Food Safety Authority (EFSA) reference(s): Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 22 (FGE.22): Ring-substituted phenolic substances from chemical groups 21 and 25 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf Flavouring Group Evaluation 58 (FGE.58) Consideration of phenol derivatives evaluated by JECFA (55th meeting) structurally related to ring substituted phenolic substances evaluated by EFSA in FGE.22 (2006) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf Scientific Opinion on Flavouring Group Evaluation 22, Revision 1 (FGE.22Rev1): Ring-substituted phenolic substances from chemical groups 21 and 25 View page or View pdf Scientific Opinion on Flavouring Group Evaluation 96 (FGE.96): Consideration of 88 flavouring substances considered by EFSA for which EU production volumes / anticipated production volumes have been submitted on request by DG SANCO. Addendum to FGE. 51, 52, 53, 54, 56, 58, 61, 62, 63, 64, 68, 69, 70, 71, 73, 76, 77, 79, 80, 83, 84, 85 and 87. View page or View pdf EPI System: View AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):622-62-8 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :12150 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 4-ethoxyphenol Chemidplus:0000622628 RTECS:SL3790000 for cas# 622-62-8   References:   4-ethoxyphenol NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 622-62-8 Pubchem (cid): 12150 Pubchem (sid): 134976757   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View FDA Indirect Additives used in Food Contact Substances: View CHEMBL: View HMDB (The Human Metabolome Database): HMDB32036 FooDB: FDB008737 Export Tariff Code: 2927.00.5000 VCF-Online: VCF Volatile Compounds in Food ChemSpider: View   Potential Blenders and core components note None Found   Potential Uses:   antioxidant in essential oils   Occurrence (nature, food, other):note   anise star anise oil Search Trop Picture   Synonyms: 1- ethoxy-4-hydroxybenzene 4- ethoxy-phenol 4- ethoxybenzolol p- ethoxyphenol para- ethoxyphenol   ethoxyphenol, p- 4- ethyloxyphenol   hydroquinone monoethyl ether   hydroquinone monoethylether 4- hydroxyphenetole p- hydroxyphenetole para- hydroxyphenetole   phenol, 4-ethoxy-   phenol, p-ethoxy-   Articles:   None found yet. 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Notes: Antioxidant in essential oils. Isol. from Chinese star anise oil (Illicium verum). Food flavourant