EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

isoascorbic acid
D-isoascorbic acid

Supplier Sponsors

Name:(2R)-2-[(1R)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one
CAS Number: 89-65-6Picture of molecule3D/inchi
Other(deleted CASRN):74242-57-2
ECHA EINECS - REACH Pre-Reg:201-928-0
FDA UNII: 311332OII1
Nikkaji Web:J2.837A
Beilstein Number:0084271
MDL:MFCD00005378
XlogP3:-1.60 (est)
Molecular Weight:176.12496000
Formula:C6 H8 O6
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:antioxidants and preservatives for fragrance and flavor
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
182.3041 Erythorbic acid (D-isoascorbic acid) View - review
EU SANCO Erythorbic acid View - review
JECFA Food Additive: Erythorbic Acid
GSFA Codex: Erythorbic Acid (Isoascorbic acid) (315)
DG SANTE Food Additives:erythorbic acid
FEMA Number:2410 D-isoascorbic acid
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):89-65-6 ; ERYTHORBIC ACID
FDA Regulation:
FDA PART 101 -- FOOD LABELING


FDA PART 145 -- CANNED FRUITS
Subpart B--Requirements for Specific Standardized Canned Fruits
Sec. 145.110 Canned applesauce.


FDA PART 155 -- CANNED VEGETABLES
Subpart B--Requirements for Specific Standardized Canned Vegetables
Sec. 155.200 Certain other canned vegetables.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart D--Chemical Preservatives
Sec. 182.3041 Erythorbic acid.
 
Physical Properties:
Appearance:white to yellowish crystalline powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: Yes
Melting Point: 164.00 to 171.00 °C. @ 760.00 mm Hg
Boiling Point: 552.00 to 553.00 °C. @ 760.00 mm Hg (est)
Flash Point:> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): -2.779 (est)
Soluble in:
 alcohol
 water, 4.00E+05 mg/L @ 25 °C (exp)
 
Organoleptic Properties:
Odor Strength:none
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antioxidants
 
Suppliers:
American International Chemical, LLC.
ERYTHORBIC ACID FCC
APAC Chemical
Erythorbic Acid
Flavor: characteristic
Erythorbic Acid is a stereoisomer of ascorbic acid. It is widely used as a preservative and color stabilizer for foods and beverages. As a vegetable-derived food additive, it can be considered natural.
Atlantic Chemicals
Erythorbic Acid
BOC Sciences
For experimental / research use only.
isoAscorbic Acid
Carbosynth
For experimental / research use only.
D-Isoascorbic acid
Foodchem International
Erythorbic Acid
Graham Chemical
Erythorbic Acid
Indis NV
For experimental / research use only.
Erythorbic Acid
Kraft Chemical
Erythorbic Acid
Penta International
D-ISOASCORBIC ACID
Penta International
ERYTHORBIC ACID
Pfaltz & Bauer
For experimental / research use only.
D-Araboascorbic acid
sds
Prinova
Erythorbic Acid
Santa Cruz Biotechnology
For experimental / research use only.
D-(-)-IsoAscorbic Acid ≥97%
Sigma-Aldrich
D-Isoascorbic acid, ≥99%, FCC, FG
sds
Certified Food Grade Products
Silver Fern Chemical
Erythorbic Acid
Odor: characteristic
Use: Erythorbic acid is mostly used as an antioxidant (industrial and food), especially in the brewing industry, and as a reducing agent for photography.
Sinofi Food Ingredients
Erythorbic Acid
Odor: characteristic
Use: Antioxidants, Bacon, Sauage, Meats, Brewing, Soft Drink, Beverage Powder, Fruit Juice, Ice Cream, Fruit Sauces, Chewing Gum, Confections, Baking Food, Yogurt, Color Stabilizer Flavoring Agent, Preservative, Nutrient, Dietary Supplement, Cosmetics, Feed, Pharmaceutical.
Sinoway Industrial
For experimental / research use only.
D-Isoascorbic Acid
(99%up, powder)
TCI AMERICA
For experimental / research use only.
D-Araboascorbic Acid >98.0%(T)
sds
Tianjin Talent Chemical
Erythorbic Acid
Zhong Ya Chemical
Erythorbic Acid
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 18000 mg/kg
International Journal of Toxicology. Vol. 18

oral-mouse LD50 8300 mg/kg
International Journal of Toxicology. Vol. 18

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
antioxidants and preservatives for fragrance and flavor
Recommendation for isoascorbic acid usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -500.00000
beverages(nonalcoholic): -100.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -20.00000
fruit ices: -20.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -380.00000
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):89-65-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :54675810
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
(2R)-2-[(1R)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one
Chemidplus:0000089656
RTECS:KF3015000 for cas# 89-65-6
 
References:
 (2R)-2-[(1R)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:89-65-6
Pubchem (cid):54675810
Pubchem (sid):134972987
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
KEGG (GenomeNet):C20364
HMDB (The Human Metabolome Database):Search
FooDB:FDB012005
Export Tariff Code:2936.27.0000
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 antioxidants
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 araboascorbic acid
D-araboascorbic acid
dextro-araboascorbic acid
D-araboascorbic acid FCC
D-(-)-isoascorbic acid
D-isoascorbic acid
dextro-isoascorbic acid
isoascorbic acid
iso-ascorbic acid
neo-cebicure
neo-cebitate
2,3-didehydro-D-erythro-hexono-1,4-lactone
2,3-didehydro-dextro-erythro-hexono-1,4-lactone
(5R)-5-(1,2-dihydroxyethyl)-3,4-dihydroxy-5-hydrofuran-2-one
(5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2(5H)-furanone
(5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
(2R)-2-[(1R)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one
 erycorbin
 erythorbic acid
D-erythorbic acid
dextro-erythorbic acid
 erythorbic acid FCC
D-erythro-3-ketohexonic acid lactone
dextro-erythro-3-ketohexonic acid lactone
D-erythro-3-oxohexonic acid lactone
dextro-erythro-3-oxohexonic acid lactone
D-erythro-hex-2-enono-1,4-lactone
3-keto-D-erythro-hexonic acid gamma-lactone
3-keto-dextro-erythro-hexonic acid gamma-lactone
D-erythroascorbic acid
dextro-erythroascorbic acid
 glucosaccharonic acid
D-erythro-hex-2-enonic acid g-lactone
 mercate 5
 saccharosonic acid
isovitamin C
 

Articles:

Info:EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS
PubMed:Toward synthesis of carbasugars (+)-gabosine C, (+)-COTC, (+)-pericosine B, and (+)-pericosine C.
PubMed:L-ascorbic Acid- and L-ascorbic Acid 2-glucoside accelerate in vivo liver regeneration and lower serum alanine aminotransaminase activity in 70% partially hepatectomized rats.
PubMed:Pericarp browning and quality management of litchi fruit by antioxidants and salicylic acid during ambient storage.
PubMed:Ultrasound-assisted lipase-catalyzed synthesis of D-isoascorbyl palmitate: process optimization and Kinetic evaluation.
PubMed:Industrial Production of L-Ascorbic Acid (Vitamin C) and D-Isoascorbic Acid.
PubMed:D-isoascorbyl palmitate: lipase-catalyzed synthesis, structural characterization and process optimization using response surface methodology.
PubMed:Sensorially important aldehyde production from amino acids in model wine systems: impact of ascorbic acid, erythorbic acid, glutathione and sulphur dioxide.
PubMed:Effect of meat ingredients (sodium nitrite and erythorbate) and processing (vacuum storage and packaging atmosphere) on germination and outgrowth of Clostridium perfringens spores in ham during abusive cooling.
PubMed:Enhancing operational stability and exhibition of enzyme activity by removing water in the immobilized lipase-catalyzed production of erythorbyl laurate.
PubMed:Antioxidant defence system during exponential and stationary growth phases of Phycomyces blakesleeanus: response to oxidative stress by hydrogen peroxide.
PubMed:Enhancing operational stability and exhibition of enzyme activity by removing water in the immobilized lipase-catalyzed production of erythorbyl laurate.
PubMed:Pigment, physicochemical, and microbiological changes related to the freshness of cracked table olives.
PubMed:Purification and characterisation of polyphenol oxidase (PPO) from eggplant (Solanum melongena).
PubMed:The effect of antibrowning agents on inhibition of potato browning, volatile organic compound profile, and microbial inhibition.
PubMed:Study on mitigation of acrylamide formation in cookies by 5 antioxidants.
PubMed:Signal transduction pathway for L-ascorbic acid- and L-ascorbic acid 2-glucoside-induced DNA synthesis and cell proliferation in primary cultures of adult rat hepatocytes.
PubMed:Symmetric and asymmetric bolaamphiphiles from ascorbic acid.
PubMed:Production, stability, and antioxidative and antimicrobial activities of two L-ascorbate analogues from phycomyces blakesleeanus: D-erythroascorbate and D-erythroascorbate glucoside.
PubMed:Determination of isoascorbic acid in fish tissue by hydrophilic interaction liquid chromatography-ultraviolet detection.
PubMed:Iron bioavailability and dietary reference values.
PubMed:A fast, simple, and reliable hydrophilic interaction liquid chromatography method for the determination of ascorbic and isoascorbic acids.
PubMed:The influence of stereochemistry of antioxidants and flavonols on oxidation processes in a model wine system: ascorbic acid, erythorbic acid, +-catechin and (-)-epicatechin.
PubMed:1,4-Dioxane-2,5-dione-type monomers derived from l-ascorbic and d-isoascorbic acids. Synthesis and polymerisation.
PubMed:Ascorbic acid conversion to erythroascorbic acid, mediated by ubiquitin.
PubMed:Microbial conversion of L-ascorbic acid to L-erythroascorbic acid.
PubMed:Effect of headgroup chirality in nanoassemblies. Part 1. Self-assembly of D-isoascorbic acid derivatives in water.
PubMed:Mechanisms and regulation of vitamin C uptake: studies of the hSVCT systems in human liver epithelial cells.
PubMed:A role for yeast glutaredoxin genes in selenite-mediated oxidative stress.
PubMed:Structure of monkey dimeric dihydrodiol dehydrogenase in complex with isoascorbic acid.
PubMed:D-Erythroascorbic acid activates cyanide-resistant respiration in Candida albicans.
PubMed:Total synthesis of (+)-achalensolide based on the rh(i)-catalyzed allenic Pauson-Khand-type reaction.
PubMed:Survey of antimicrobial effects of beef carcass intervention treatments in very small state-inspected slaughter plants.
PubMed:Determination of ascorbic acid and its related compounds in foods and beverages by hydrophilic interaction liquid chromatography.
PubMed:Oxyresveratrol as an antibrowning agent for cloudy apple juices and fresh-cut apples.
PubMed:NAD+-specific D-arabinose dehydrogenase and its contribution to erythroascorbic acid production in Saccharomyces cerevisiae.
PubMed:Mechanism of L-ascorbic acid uptake by rabbit corneal epithelial cells: evidence for the involvement of sodium-dependent vitamin C transporter 2.
PubMed:Synthesis of a versatile (S)-3-(hydroxymethyl)butane-1,2,4-triol building block and its application for the stereoselective synthesis of N-homoceramides.
PubMed:Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics.
PubMed:Preventing lipid oxidation during recovery of functional proteins from herring (Clupea harengus) fillets by an acid solubilization process.
PubMed:Characterisation and biosynthesis of D-erythroascorbic acid in Phycomyces blakesleeanus.
PubMed:Cloning and characterization of gluconolactone oxidase of Penicillium cyaneo-fulvum ATCC 10431 and evaluation of its use for production of D-erythorbic acid in recombinant Pichia pastoris.
PubMed:Properties of poly-aminophenylboronate coatings in capillary electrophoresis for the selective separation of diastereoisomers and glycoproteins.
PubMed:Erythorbic acid is a potent enhancer of nonheme-iron absorption.
PubMed:Towards the development of an integrated capillary electrophoresis optical biosensor.
PubMed:Effects of ascorbic acid and analogs on the activity of testicular hyaluronidase and hyaluronan lyase on hyaluronan.
PubMed:Assessing plant response to ambient ozone: growth of ozone-sensitive loblolly pine seedlings treated with ethylenediurea or sodium erythorbate.
PubMed:Effect of smoking on erythorbic acid pharmacokinetics.
PubMed:Effects of L-ascorbic acid on lysyl oxidase in the formation of collagen cross-links.
PubMed:Measurement of ascorbic acid and dehydroascorbic acid in biological samples.
PubMed:Salt- and glyphosate-induced increase in glyoxalase I activity in cell lines of groundnut (Arachis hypogaea).
PubMed:The effects of ascorbic acid on cartilage metabolism in guinea pig articular cartilage explants.
PubMed:Reduction of dehydroerythorbic acid in vitamin C-deficient guinea pigs.
PubMed:Syntheses of D- and L-cyclopentenone derivatives using ring-closing metathesis: versatile intermediates for the synthesis of D- and L-carbocyclic nucleosides.
PubMed:Mitochondrial NADH-cytochrome b(5) reductase plays a crucial role in the reduction of D-erythroascorbyl free radical in Saccharomyces cerevisiae.
PubMed:Selective intercalation of charge neutral intercalators into GG and CG steps: implication of HOMO-LUMO interaction for sequence-selective drug intercalation into DNA.
PubMed:Quantification of L-ascorbic acid and total ascorbic acid in fruits and spinach by capillary zone electrophoresis.
PubMed:Innovation in sodium erythorbate production: the use of membrane-reactors.
PubMed:Water-soluble antioxidants inhibit macrophage recognition of oxidized erythrocytes.
PubMed:Deficiency of D-erythroascorbic acid attenuates hyphal growth and virulence of Candida albicans.
PubMed:The biosynthesis of erythroascorbate in Saccharomyces cerevisiae and its role as an antioxidant.
PubMed:Prevention of the formation of mutagenic and/or carcinogenic heterocyclic amines by food factors.
PubMed:Biosynthesis of L-ascorbic acid and conversion of carbons 1 and 2 of L-ascorbic acid to oxalic acid occurs within individual calcium oxalate crystal idioblasts.
PubMed:Effect of erythorbic acid on cooked color in ground beef.
PubMed:Estimates of the theoretical maximum daily intake of erythorbic acid, gallates, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) in Italy: a stepwise approach.
PubMed:Maintaining quality of fresh-cut mangoes using antibrowning agents and modified atmosphere packaging.
PubMed:Generation of aniline from a subsidiary colour of food yellow no. 5 (sunset yellow FCF).
PubMed:Time-dependent changes of tissue erythorbic acid concentrations in guinea pigs.
PubMed:Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with tris[2-carboxyethyl]phosphine hydrochloride.
PubMed:Interconversion between dehydro-L-ascorbic acid and L-ascorbic acid.
PubMed:Biosynthesis of L-ascorbic acid (vitamin C) by Saccharomyces cerevisiae.
PubMed:Simple in-line postcolumn oxidation and derivatization for the simultaneous analysis of ascorbic and dehydroascorbic acids in foods.
PubMed:L-Ascorbic acid and L-galactose are sources for oxalic acid and calcium oxalate in Pistia stratiotes.
PubMed:Effect of food reductones on the generation of the pyrazine cation radical and on the formation of the mutagens in the reaction of glucose, glycine and creatinine.
PubMed:Synthesis of both enantiomers of 4-vinyl oxazolidin-2-one from a single precursor: D-isoascorbic acid.
PubMed:Induction of cell death by ascorbic acid derivatives in human renal carcinoma and glioblastoma cell lines.
PubMed:Epimeric separation of L-ascorbic acid and D-isoascorbic acid by capillary zone electrophoresis.
PubMed:Human vitamin C (L-ascorbic acid) transporter SVCT1.
PubMed:Extending storage life of fresh-cut apples using natural products and their derivatives.
PubMed:Bacterial production of D-erythroascorbic acid and L-ascorbic acid through functional expression of Saccharomyces cerevisiae D-arabinono-1,4-lactone oxidase in Escherichia coli.
PubMed:Activation of Ca(2+)-dependent K(+) current by nordihydroguaiaretic acid in porcine coronary arterial smooth muscle cells.
PubMed:Indirect detection of organic acids in non-aqueous capillary electrophoresis.
PubMed:Improved method for simultaneous determination of ascorbic acid and dehydroascorbic acid, isoascorbic acid and dehydroisoascorbic acid in food and biological samples.
PubMed:D-Erythroascorbic acid is an important antioxidant molecule in Saccharomyces cerevisiae.
PubMed:Use of a laccase-column for flow-injection calorimetry.
PubMed:D-arabinose dehydrogenase and its gene from Saccharomyces cerevisiae.
PubMed:Contents of erythorbic acid in the tissues of guinea pigs intraperitoneally administered erythorbic acid.
PubMed:Role of hydrogen peroxide in cytotoxicity induction by ascorbates and other redox compounds.
PubMed:Ascorbic acid-based inhibitors of alpha-amylases.
PubMed:Synthesis of beta-difluorine-containing amino acids.
PubMed:Evaluation of biodegradable rifampicin-bearing microsphere formulations using a stability-indicating high-performance liquid chromatographic assay.
PubMed:Uncoupling of incorporation of ascorbic acid and apoptosis induction.
PubMed:Dehydroascorbic acid prevents apoptosis induced by oxidized low-density lipoprotein in human monocyte-derived macrophages.
PubMed:Spontaneous conversion of L-dehydroascorbic acid to L-ascorbic acid and L-erythroascorbic acid.
PubMed:Study of the interaction of dithranol with heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin in solution and in the solid state.
PubMed:Separative determination of ascorbic acid analogs contained in mushrooms by high-performance liquid chromatography.
PubMed:Activities of D- and L-xyloascorbic acid and D- and L-araboascorbic acid as a cofactor for dopamine beta-hydroxylase reaction.
PubMed:Ascorbic acid is a stimulatory cofactor for mitochondrial glycerol-3-phosphate dehydrogenase.
PubMed:Duodenal ferri-reductase is not mediated by ascorbate.
PubMed:Liquid chromatographic measurement of L-ascorbic acid and D-ascorbic acid in biological samples.
PubMed:D-arabinose dehydrogenase and biosynthesis of erythroascorbic acid in Candida albicans.
PubMed:Relationship between ascorbyl radical intensity and apoptosis-inducing activity.
PubMed:Fruits and vegetables: there is no substitute.
PubMed:Effects of erythorbic acid on vitamin C metabolism in young women.
PubMed:Analysis of ascorbate in plant tissues by high-performance capillary zone electrophoresis.
PubMed:Simultaneous determination of ascorbic, dehydroascorbic, isoascorbic, and dehydroisoascorbic acids in meat-based food products by liquid chromatography with postcolumn fluorescence detection: a method extension.
PubMed:Evidence for an action of araboascorbic acid on dopaminergic pathways of the corpus striatum.
PubMed:Conversion of D-arabinose to D-erythroascorbic acid and oxalic acid in Sclerotinia sclerotiorum.
PubMed:Requirement for Na(+)-dependent ascorbic acid transport in osteoblast function.
PubMed:Vitamin C redox reactions in blood of normal and malaria-infected mice studied with isoascorbate as a nonisotopic marker.
PubMed:Vitamin C activity of erythorbic acid in ascorbic acid-deficient guinea pigs.
PubMed:Urinary ascorbic acid--HPLC determination and application as a noninvasive biomarker of hepatic response.
PubMed:Characterisation of D-arabinono-1,4-lactone oxidase from Candida albicans ATCC 10231.
PubMed:Expression of a rabbit renal ascorbic acid transporter in Xenopus laevis oocytes.
PubMed:Homogentisic acid and structurally related compounds as intermediates in plasma soluble melanin formation and in tissue toxicities.
PubMed:Kinetic properties of light-dependent ascorbic acid oxidation by melanin.
PubMed:Increased susceptibility of stored erythrocytes to anti-band 3 IgG autoantibody binding.
PubMed:Cytotoxic effect of ascorbate and its derivatives on cultured malignant and nonmalignant cell lines.
PubMed:Measurement of vitamin C by capillary electrophoresis in biological fluids and fruit beverages using a stereoisomer as an internal standard.
PubMed:Determination of ascorbic acid and isoascorbic acid by capillary zone electrophoresis: application to fruit juices and to a pharmaceutical formulation.
PubMed:Overestimation of vitamin C status because of the erythorbic acid content of foods.
PubMed:Topical vitamin C protects porcine skin from ultraviolet radiation-induced damage.
PubMed:Mode of formation of quinoxaline versus 2[1H]-quinoxalinone rings from dehydro-D-erythorbic acid.
PubMed:Stereospecific effects of ascorbic acid and analogues on D1 and D2 agonist binding.
PubMed:The simultaneous measurement of uric acid and ascorbic acid in the lateral ventricles of freely moving rats by brain microdialysis and electrochemical detection.
PubMed:Influence of dietary intakes of erythorbic acid on plasma vitamin C analyses.
PubMed:Inhibiting effect of ascorbic acid on the growth of human mammary tumor xenografts.
PubMed:Mechanisms of ascorbic acid-induced inhibition of chemical transformation in C3H/10T1/2 cells.
PubMed:Comparison of absorption of erythorbic acid and ascorbic acid in guinea pig small intestine.
PubMed:Inhibition of dimeric dihydrodiol dehydrogenases of rabbit and pig lens by ascorbic acid.
PubMed:Ascorbic acid regeneration in chromaffin granules. In situ kinetics.
PubMed:The effects of ascorbic acid on collagen synthesis by cultured human skin fibroblasts.
PubMed:Characteristics of ascorbic acid uptake by isolated ox neurohypophyseal nerve terminals and the influence of glucocorticoid and tri-iodothyronine on uptake.
PubMed:Characterization of ascorbic acid uptake by isolated rat kidney cells.
PubMed:Decrease of Na(+)-Ca2+ exchange activity by ascorbate in rat brain membrane vesicles.
PubMed:Measurement of ascorbic acid and erythorbic acid in processed meat by HPLC.
PubMed:Improved extraction method for avoiding the interference of ascorbic acid in the spectrophotometric determination of nitrite in meat products.
PubMed:The nitric oxide reductase of Paracoccus denitrificans.
PubMed:Net vitamin C activity of erythorbic acid in guinea pigs.
PubMed:Enzymatic formation of ascorbic acid in liver homogenate of mice fed dietary ascorbic acid.
PubMed:Ascorbic acid potentiates the inhibitory effect of dopamine on prolactin release: a putative supplementary agent for PIF.
PubMed:Effectiveness of isoascorbate versus ascorbate as an inducer of collagen synthesis in primary avian tendon cells.
PubMed:The preparation of 2'-deoxy-2'-fluoro-1',2'-seconucleosides as potential antiviral agents.
PubMed:The bactericidal effect of isoascorbic acid combined with mild heat.
PubMed:Ascorbic acid and erythorbic acid metabolism in nonpregnant women.
PubMed:Tumorigenicity study of sodium erythorbate administered orally to mice.
PubMed:Effect of erythorbic acid administration on activities of drug metabolic enzyme and phosphatases in guinea pigs administered an adequate amount of ascorbic acid.
PubMed:Comparison of the ion exclusion chromatographic method with the Monier-Williams method for determination of total sulfite in foods.
PubMed:Effect of the reducing environment on the accumulation of elastin and collagen in cultured smooth-muscle cells.
PubMed:Electrogenic Na+-ascorbate cotransport in cultured bovine pigmented ciliary epithelial cells.
PubMed:Effect of exogenous ascorbic acid intake on biosynthesis of ascorbic acid in mice.
PubMed:The inhibition of the growth of Bacillus cereus in liver sausage.
PubMed:Effect of graded doses of erythorbic acid on activities of drug metabolic enzyme and phosphatases in guinea pigs.
PubMed:Ascorbic acid potentiates the inhibitory effect of dopamine on prolactin release in primary cultured rat pituitary cells.
PubMed:Ascorbic acid deficiency and hepatic UDP-glucuronyltransferase.
PubMed:Active transport of ascorbate across the isolated rabbit ciliary epithelium.
PubMed:Ion suppression reversed-phase high-performance liquid chromatography method for the separation of L-ascorbic acid in fresh fruit juice.
PubMed:L-ascorbic acid modulates 5-lipoxygenase activity in human polymorphonuclear leukocytes.
PubMed:Control of nucleotide and erythroascorbic acid pools by cyclic AMP in Neurospora crassa.
PubMed:An internal standard method for the unattended high-performance liquid chromatographic analysis of ascorbic acid in blood components.
PubMed:Ascorbic and dehydroascorbic acids simultaneously quantified in biological fluids by liquid chromatography with fluorescence detection, and comparison with a colorimetric assay.
PubMed:Erythorbic acid content in tissues of guinea pigs administered erythorbic acid.
PubMed:Interference of ascorbic and isoascorbic acids in the spectrophotometric determination of nitrite by the diazotization-coupling technique.
PubMed:Absence of promotion potential for calcium L-ascorbate, L-ascorbic dipalmitate, L-ascorbic stearate and erythorbic acid on rat urinary bladder carcinogenesis.
PubMed:Determination of ascorbic acid in human urine by high-performance liquid chromatography coupled with fluorimetry after post-column derivatization with benzamidine.
PubMed:Virus-inactivating effect of D-isoascorbic acid.
PubMed:Changes in the urine and scanning electron microscopically observed appearance of the rat bladder following treatment with tumor promoters.
PubMed:Safety and necessity of antioxidants: EEC approach.
PubMed:Effect of ascorbic, isoascorbic and dehydroascorbic acids on the growth and survival of Campylobacter jejuni.
PubMed:Effect of graded doses of erythorbic acid on ascorbic acid content of tissues of guinea pigs.
PubMed:[Antagonistic effect of ascorbic acid on caffeine-induced elevation of cerebrospinal fluid Ca2+ in rabbits].
PubMed:Effect of erythorbic acid administration on ascorbic acid content in guinea pig tissues.
PubMed:High-performance liquid chromatographic separation of ascorbic acid, erythorbic acid, dehydroascorbic acid, dehydroerythorbic acid, diketogulonic acid, and diketogluconic acid.
PubMed:Effects of sodium L-ascorbate and related compounds on rat stomach carcinogenesis initiated by N-methyl-N'-nitro-N-nitrosoguanidine.
PubMed:Biological nature of the effect of ascorbic acids on the growth of human leukemic cells.
PubMed:An electron transfer dependent membrane potential in chromaffin-vesicle ghosts.
PubMed:Ascorbic acid stability in aqueous solutions.
PubMed:Changes in response to ascorbic acid administered orally to rat pups: lung collagen, elastin and protein synthesis.
PubMed:Ascorbic acid mediates acetylcholine receptor increase induced by brain extract on myogenic cells.
PubMed:Characterization of alkaline phosphatase inactivation by ascorbic acid.
PubMed:Modifications induced by ascorbic acid on alkaline phosphatase fluorescence.
PubMed:Sodium erythorbate is not carcinogenic in F344 rats.
PubMed:Primary mutagenicity screening of food additives currently used in Japan.
PubMed:Promotion by ascorbic acid, sodium erythorbate and ethoxyquin of neoplastic lesions in rats initiated with N-butyl-N-(4-hydroxybutyl) nitrosamine.
PubMed:Decrease in bone density in young male guinea pigs fed high levels of ascorbic acid.
PubMed:Relationship between ascorbic acid and cell division.
PubMed:Structure of ascorbic acid and its biological function. Determination of the conformation of ascorbic acid and isoascorbic acid by infrared and ultraviolet investigations.
PubMed:Structure of ascorbic acid and its biological function. VI. Its importance for the Na+/K+-transport.
PubMed:Structure of ascorbic acid and its biological function. I. ESR determination of the ascorbyl radical in biological samples and in model systems.
PubMed:Effect of erythorbate on N-methyl-N'-nitro-N-nitrosoguanidine-induced stomach carcinogenesis in F344 rats.
PubMed:Structure of ascorbic acid and its biological function: V. Transport of ascorbate and isoascorbate across artificial membranes as studied by the spin label technique.
PubMed:Ascorbate-induced lipid peroxidation and inhibition of [3H]spiroperidol binding in neostriatal membrane preparations.
PubMed:The effect of vitamin C on in vivo lipid peroxidation in guinea pigs as measured by pentane and ethane production.
PubMed:Modulation of alkaline phosphatase in different organs by ascorbic acid and related compounds.
PubMed:Influence of erythorbic acid on ascorbic acid retention and elimination in the mouse.
PubMed:Differential determination of L-ascorbic acid and D-isoascorbic acid by reversed-phase high-performance liquid chromatography with electrochemical detection.
PubMed:Drug-nitrite interactions in human saliva: effects of food constituents on carcinogenic N-nitrosamine formation.
PubMed:Inhibitory effects of ascorbic acid on the binding of [3H]dopamine antagonists to neostriatal membrane preparations: relationship to lipid peroxidation.
PubMed:Oxidation of reduced pyridine nucleotide by a system using ascorbate and hydrogen peroxide from plants and algae.
PubMed:A postabsorption effect of L-ascorbic acid on copper metabolism in chicks.
PubMed:Na+-dependent, potential-sensitive L-ascorbate transport across brush border membrane vesicles from kidney cortex.
PubMed:High-performance liquid chromatographic separation of ascorbic acid, erythorbic acid, dehydroascorbic acid, dehydroerythorbic acid, diketogulonic acid, and diketogluconic acid.
PubMed:The antiscorbutic action of L-ascorbic acid and D-isoascorbic acid (erythorbic acid) in the guinea pig.
PubMed:Separative determination of ascorbic acid and erythorbic acid in animal tissues by high-performance liquid chromatography.
PubMed:Separative determination of ascorbic acid and erythorbic acid by high-performance liquid chromatography.
PubMed:Generation and reactivities of various types of oxygen radicals.
PubMed:The search for the specific factor in scurvy.
PubMed:[Effect of L-ascorbic and D-isoascorbic acids on induced formation of tyrosine aminotransferase in rat liver].
PubMed:[Isolation and characterisation of L-ascorbic acid oxidase (EC 1.10.3.3) from wheat flour (author's transl)].
PubMed:Influence of ascorbic acid and erythorbic acid on drug metabolism in the cynomolgus monkey.
PubMed:On the dual action of ascorbate and erythorbate on rat liver lysosomes.
PubMed:Absorption of vitamin C from the human buccal cavity.
PubMed:In vitro effect of D-isoascorbic acid and betaine hydrate alone and in combination on normal and malignant cells.
PubMed:Effect of flavonoids on vitamin C activity of D-isoascorbic acid.
PubMed:Effects of ascorbic acid deficiency and of erythorbic acid on blood components in the Cynomolgus monkey.
PubMed:In vitro studies of the interaction between ascorbic acid and rat tail tendon.
PubMed:Interaction of erythorbic acid with ascorbic acid catabolism.
PubMed:Biosynthesis of stizolobinic acid and stizolobic acid in higher plants. An enzyme system(s) catalyzing the conversion of dihydroxyphenylalanine into stizolobinic acid and stizolobic acid from etiolated seedlings of Stizolobium hassjoo.
PubMed:Interaction of erythorbic acid with ascorbic acid catabolism.
PubMed:L-Ascorbic acid and D-isoascorbic acid in a common cold survey.
PubMed:D-Isoascorbic acid investigated in a common cold survey.
PubMed:Influence of erythorbic acid on the vitamin C status in guinea-pigs.
PubMed:[Decomposition of L-ascorbic acid in the presence of D-araboascorbic acid. 3. On decomposition of L-ascorbic acid in the presence of D-araboascorbic acid under atmospheric condition (author's transl)].
PubMed:[Studies on the autoxidation of carbohydrates and its derivatives. VII. Reaction of erythorbic acid with phenylhydrazine].
PubMed:Protective effect of ascorbic acid, isoascorbic acid and mannitol against tetracycline-induced nephrotoxicity.
PubMed:[Studies on the decomposition of L-ascorbic acid in the coexistence of D-araboascorbic acid. II. On the anaerobic decomposition of L-ascorbic acid in the coexistence of D-araboascorbic acid].
PubMed:Vitamin C activity of D-isoascorbic acid for the guinea pig.
PubMed:Turnover rates of D-isoascorbic acid and L-ascorbic acid in guinea pig organs.
PubMed:[Studies on the decomposition of L-ascorbic acid in the coexist of D-araboascorbic acid. I. Gas-liquid chromatographic separation and determination of L-ascorbic acid and D-araboascorbic acid].
PubMed:The uptake of D-araboascorbic acid (D-isoascorbic acid) by guinea-pig tissues.
PubMed:Differential determination of D-isoascorbic acid and L-ascorbic acid in guinea pig organs.
PubMed:Transfer of D-isoascorbic acid and L-ascorbic acid into guinea pig eyes.
PubMed:Antiscorbutic activity of D-araboascorbic acid.
PubMed:The effects of erythorbic Acid treatments on melanin synthesis and on the adult life span in Drosophila melanogaster: preliminary report.
PubMed:ESTIMATION OF ERYTHORBIC ACID IN THE PRESENCE OF ASCORBIC ACID BY USE OF THE ASCORBASE OF MYROTHECIUM VERRUCARIA.
PubMed:HUMAN METABOLISM OF L-ASCORBIC ACID AND ERYTHORBIC ACID.
PubMed:Comparative metabolic response to erythorbic acid and ascorbic acid by the human.
PubMed:Studies on the pathways of D-araboascorbic acid synthesis by Penicillium.
PubMed:[Research on rotatory dispersion. Rotatory dispersion of isoascorbic acid].
PubMed:Biochemical studies on d-araboascorbic acid in vitamin C deficiency.
PubMed:COMPARISON of chemical and biologic activities of L-ascorbic acid and D-isoascorbic acid.
PubMed:Effect of ascorbic acid, d-isoascorbic acid and glucoascorbic acid on cobalt polycythemia in the rat and rabbit.
PubMed:The reaction of L-ascorbic and D-isoascorbic acid with nicotinic acid and its amide.
 
Notes:
food antioxidant; (l)-isomer is ascorbic acid. Prod. from glucose by Penicillium spp. Antioxidant for foods and soft drinks. Flavouring ingredient; colouring preservative/antioxidant in fruit and meat products Erythorbic acid, formerly known as isoascorbic acid and D-araboascorbic acid, is a stereoisomer of ascorbic acid (vitamin C). It is a vegetable-derived food additive produced from sucrose. It is denoted by E number E315, and is widely used as an antioxidant in processed foods. [Wikipedia]
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