Name: | (1aS,4aS,7S,7aS,7bR)-1,1,7-trimethyl-4-methylidene-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulene |
CAS Number: | 14682-34-9 | 3D/inchi
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Other(deleted CASRN): | 11026-29-2 |
FDA UNII: | Search |
Nikkaji Web: | J15.448B |
XlogP3-AA: | 4.70 (est) |
Molecular Weight: | 204.35628000 |
Formula: | C15 H24 |
NMR Predictor: | Predict (works with chrome, Edge or firefox) |
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Boiling Point: | 121.00 °C. @ 10.00 mm Hg
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Boiling Point: | 260.00 to 265.00 °C. @ 760.00 mm Hg
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Vapor Pressure: | 0.023000 mmHg @ 25.00 °C. (est) |
Flash Point: | 223.00 °F. TCC ( 106.11 °C. )
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logP (o/w): | 6.427 (est) |
Soluble in: |
| alcohol | | water, 0.07057 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | natural substances and extractives |
Recommendation for (-)-aromadendrene usage levels up to: | | not for fragrance use.
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Recommendation for (-)-aromadendrene flavor usage levels up to: |
| not for flavor use.
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Safety References:
EPI System: View |
AIDS Citations:Search |
Cancer Citations:Search |
Toxicology Citations:Search |
EPA ACToR:Toxicology Data |
EPA Substance Registry Services (SRS):Registry |
Laboratory Chemical Safety Summary :177445 |
National Institute of Allergy and Infectious Diseases:Data |
(1aS,4aS,7S,7aS,7bR)-1,1,7-trimethyl-4-methylidene-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulene |
Chemidplus:0014682349 |
References:
| (1aS,4aS,7S,7aS,7bR)-1,1,7-trimethyl-4-methylidene-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulene |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 177445 |
Pubchem (sid): | 135154702 |
Pherobase: | View |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
(-)-10(14)- | aromadendrene | L- | aromadendrene | laevo- | aromadendrene | | aromadendrene, (-)- | 1H- | cycloprop(e)azulene, decahydro-1,1,7-trimethyl-4-methylene-, (1aS,4aS,7S,7aS,7bR)- | (1aS,4aS,7S,7aS,7bR)- | decahydro-1,1,7-trimethyl-4-methylene-1H-cycloprop(e)azulene | beta- | diploalbicene | (1aS,4aS,7S,7aS,7bR)-1,1,7- | trimethyl-4-methylidene-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulene |
Articles:
PubMed:Synergistic properties of the terpenoids aromadendrene and 1,8-cineole from the essential oil of Eucalyptus globulus against antibiotic-susceptible and antibiotic-resistant pathogens. |
PubMed:Induction of defensive response in Eucalyptus globulus plants and its persistence in vegetative propagation. |
PubMed:Oligo-carrageenan kappa-induced reducing redox status and increase in TRR/TRX activities promote activation and reprogramming of terpenoid metabolism in Eucalyptus trees. |
PubMed:The total synthesis of (-)-aromadendrene. |
PubMed:A comparative analysis of essential oils of Goniothalamus macrocalyx Ban., Goniothalamus albiflorus Ban. and Goniothalamus tamirensis Pierre ex Fin. & Gagnep. from Vietnam. |
PubMed:Single- versus Multiple-Pest Infestation Affects Differently the Biochemistry of Tomato (Solanum lycopersicum 'Ailsa Craig'). |
PubMed:Composition, in vitro Anti-inflammatory, Antioxidant and Antimicrobial Activities of Essential Oils from Leaf and Twig Parts of Cupressus cashmeriana. |
PubMed:Antimicrobial activity of the essential oil of Tetradenia riparia (Hochst.) Codd. (Lamiaceae) against cariogenic bacteria. |
PubMed:Bioactivity and chemical characterisation of Lophostemon suaveolens - an endemic Australian Aboriginal traditional medicinal plant. |
PubMed:Antimicrobial Potential and Chemical Characterization of Serbian Liverwort (Porella arboris-vitae): SEM and TEM Observations. |
PubMed:Biomimetic synthesis of (+)-ledene, (+)-viridiflorol, (-)-palustrol, (+)-spathulenol, and psiguadial A, C, and D via the platform terpene (+)-bicyclogermacrene. |
PubMed:Chemical composition of essential oil and in vitro antioxidant activities of the essential oil and methanol extracts of Eucalyptus loxophleba. |
PubMed:Three new cembranoid-type diterpenes from Red Sea soft coral Sarcophyton glaucum: isolation and antiproliferative activity against HepG2 cells. |
PubMed:Hepatoprotection of sesquiterpenoids: a quantitative structure-activity relationship (QSAR) approach. |
PubMed:Anti-inflammatory, antinociceptive activity of an essential oil recipe consisting of the supercritical fluid CO2 extract of white pepper, long pepper, cinnamon, saffron and myrrh in vivo. |
PubMed:Influence of combinations of digitonin with selected phenolics, terpenoids, and alkaloids on the expression and activity of P-glycoprotein in leukaemia and colon cancer cells. |
PubMed:Assessment of the chemical composition and in vitro antimicrobial potential of extracts of the liverwort Scapania aspera. |
PubMed:Volatile organic compounds of conspecific-damaged Eucalyptus benthamii influence responses of mated females of Thaumastocoris peregrinus. |
PubMed:Acaricidal activity of essential oils from five endemic conifers of New Caledonia on the cattle tick Rhipicephalus (Boophilus) microplus. |
PubMed:Insecticidal and genotoxic activity of Psoralea corylifolia Linn. (Fabaceae) against Culex quinquefasciatus Say, 1823. |
PubMed:Antibacterial activity of essential oils from Eucalyptus and of selected components against multidrug-resistant bacterial pathogens. |
PubMed:Essential oils from five species of Annonaceae from Vietnam. |
PubMed:Assessment of Volatile Chemical Composition of the Essential Oil of Jatropha ribifolia (Pohl) Baill by HS-SPME-GC-MS Using Different Fibers. |
PubMed:Chemical composition and biological activities of the essential oil from Calamintha nepeta plants from the wild in southern Italy. |
PubMed:Bioactive phytochemicals of leaf essential oils of Cinnamomum osmophloeum prevent lipopolysaccharide/D-galactosamine (LPS/D-GalN)-induced acute hepatitis in mice. |
PubMed:Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells. |
PubMed:Digitonin synergistically enhances the cytotoxicity of plant secondary metabolites in cancer cells. |
PubMed:Chemotaxonomical markers in essential oil of Murraya koenigii. |
PubMed:[GC-MS study on fingerprint of volatile oil from Kadsura heteroclita]. |
PubMed:Essential oil composition of Eucalyptus procera Dehnh. leaves from central Iran. |
PubMed:Changes in volatile compound composition of Antrodia camphorata during solid state fermentation. |
PubMed:Volatile compounds in the stem bark of Sclerocarya birrea (Anacardiaceae) possess antimicrobial activity against drug-resistant strains of Helicobacter pylori. |
PubMed:Helichrysum gymnocephalum essential oil: chemical composition and cytotoxic, antimalarial and antioxidant activities, attribution of the activity origin by correlations. |
PubMed:Chemical composition and antioxidant, antimicrobial, and larvicidal activities of the essential oils of Annona salzmannii and A. pickelii (Annonaceae). |
PubMed:Variation in volatile leaf oils of five Eucalyptus species harvested from Jbel Abderrahman arboreta (Tunisia). |
PubMed:Comparison of Eucalyptus cinerea essential oils produced by hydrodistillation and supercritical carbon dioxide extraction. |
PubMed:Allelochemical effects of volatile compounds and organic extracts from Muscodor yucatanensis, a tropical endophytic fungus from Bursera simaruba. |
PubMed:Induction of sesquiterpenes, phytoesterols and extracellular pathogenesis-related proteins in elicited cell cultures of Capsicum annuum. |
PubMed:A chemical marker proposal for the Lantana genus: composition of the essential oils from the leaves of Lantana radula and L. canescens. |
PubMed:Variation in volatile leaf oils of twelve eucalyptus species harvested from Hajeb Layoun arboreta (Tunisia). |
PubMed:Variability of the needle essential oils of Pinus heldreichii from different populations in Montenegro and Serbia. |
PubMed:[Study of chemical constituents of essential oil from flowers of Mikania micrantha H.B.K]. |
PubMed:Structure-activity relationships of aromadendranes in uterus-relaxant activity. |
PubMed:Biotransformation of terpenoids by mammals, microorganisms, and plant-cultured cells. |
PubMed:Determination of specific volatile organic compounds synthesised during Tuber borchii fruit body development by solid-phase microextraction and gas chromatography/mass spectrometry. |
PubMed:Analysis of atmospheric sesquiterpenes: sampling losses and mitigation of ozone interferences. |
PubMed:Antimicrobial activity and chemical composition of Senecio sandrasicus on antibiotic resistant staphylococci. |
PubMed:The chemical composition of the essential oils of Euphorbia caracasana and E. cotinifolia (Euphorbiaceae) from Venezuela. |
PubMed:Detailed analysis of the essential oil from Cistus albidus L. by combination of GC/RI, GC/MS and 13C-NMR spectroscopy. |
PubMed:Chemical composition, antifungal and antitumor properties of ether extracts of Scapania verrucosa Heeg. and its endophytic fungus Chaetomium fusiforme. |
PubMed:Chemical constituents and larvicidal property of the essential oil of Blumea mollis (D. Don) Merr. against Culex quinquefasciatus. |
PubMed:Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities. |
PubMed:Composition and antimicrobial activity of the essential oil of Hypericum rumeliacum subsp. apollinis (Boiss. & Heldr.). |
PubMed:Monitoring and fast detection of mycotoxin-producing fungi based on headspace solid-phase microextraction and headspace sorptive extraction of the volatile metabolites. |
PubMed:The stereochemistry of ledol from Renealmia chrysotrycha: an NMR study. |
PubMed:Chemical, physical and antimicrobial properties of essential oils of Leptospermum scoparium and Kunzea ericoides. |
PubMed:Melaleuca oil (tea tree oil) dermatitis. |
PubMed:[Analysis of chemical constituent of essential oil in Lonicera japonnica Thunb. cultivated on the northern plain of Henan Province]. |
PubMed:Variability of the needle essential oils of Pinus peuce from different populations in Montenegro and Serbia. |
PubMed:Comparative study on volatile components of Nardostachys rhizome. |
PubMed:Composition of Eucalyptus camaldulensis volatiles using direct thermal desorption coupled with comprehensive two-dimensional gas chromatography-time-of-flight-mass spectrometry. |
PubMed:Bullatenone, 1,3-dione and sesquiterpene chemotypes of Lophomyrtus species. |
PubMed:[Gas chromatography for analysis of essential oils. Characteristics of essential oil of Dracocephalum species and the influence of extraction method on its composition]. |
PubMed:[Headspace solid-phase microextraction-gas chromatography-mass spectrometry for analysis of volatile components from Atractlodes macrocephala Koidz]. |
PubMed:Effect of intraspecific competition and substrate type on terpene emissions from some Mediterranean plant species. |
PubMed:Comparison of eucalyptus camaldulensis Dehn. oils from Mozambique as obtained by hydrodistillation and supercritical carbon dioxide extraction. |
PubMed:The steam volatile oil of Wollemia nobilis and its comparison with other members of the Araucariaceae (Agathis and Araucaria). |
PubMed:Solid phase microextraction of volatile constituents from individual fresh Eucalyptus leaves of three species. |
PubMed:Diversity in cyclic sesquiterpene production by Gossypium hirsutum. |
PubMed:Composition of essential oils of Laurus nobilis, L. nobilis var. angustifolia and Laurus azorica. |
PubMed:Chemical studies of marine invertebrates. XXVII. On the absolute configuration of aromadendrane sesquiterpenes from the soft coral Cespitularia aff. subviridis. |
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