Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Appearance: | colorless to pale yellow clear liquid (est) |
Assay: | 97.00 to 100.00 %
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Food Chemicals Codex Listed: | Yes |
Specific Gravity: | 0.97000 to 0.98000 @ 25.00 °C.
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Pounds per Gallon - (est).: | 8.071 to 8.155
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Refractive Index: | 1.44300 to 1.44700 @ 20.00 °C.
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Boiling Point: | 234.00 °C. @ 760.00 mm Hg
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Boiling Point: | 132.00 to 133.00 °C. @ 20.00 mm Hg
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Acid Value: | 8.00 max. KOH/g
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Vapor Pressure: | 0.041000 mmHg @ 25.00 °C. (est) |
Vapor Density: | >1 ( Air = 1 ) |
Flash Point: | 230.00 °F. TCC ( 110.00 °C. )
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logP (o/w): | 1.432 (est) |
Shelf Life: | 24.00 month(s) or longer if stored properly. |
Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
Soluble in: |
| alcohol | | dipropylene glycol | | water, slightly | | water, 3632 mg/L @ 25 °C (est) |
Insoluble in: |
| water |
Organoleptic Properties:
Odor Type: | coconut |
Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
Odor Description: at 10.00 % in dipropylene glycol. | sweet coconut waxy creamy tonka dairy fatty |
Substantivity: | 144 Hour(s) |
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Cosmetic Information:
Safety Information:
Most important hazard(s): | Xi - Irritant |
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R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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Human Experience: | 12 % solution: no irritation or sensitization. |
Oral/Parenteral Toxicity: | |
oral-rat LD50 4400 mg/kg Food and Cosmetics Toxicology. Vol. 14, Pg. 821, 1976.
oral-rat LD50 > 5000 mg/kg (Moreno, 1974c)
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Dermal Toxicity: | |
skin-rabbit LD50 > 5000 mg/kg (Moreno, 1974c)
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Inhalation Toxicity: | |
Not determined
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Safety in Use Information:
Category: | flavor and fragrance agents |
Recommendation for gamma-octalactone usage levels up to: | | 12.0000 % in the fragrance concentrate.
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Maximised Survey-derived Daily Intakes (MSDI-EU): | 430.00 (μg/capita/day) |
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
publication number: 3 |
Click here to view publication 3 |
| average usual ppm | average maximum ppm |
baked goods: | - | 17.00000 |
beverages(nonalcoholic): | - | 4.80000 |
beverages(alcoholic): | - | - |
breakfast cereal: | - | - |
cheese: | - | - |
chewing gum: | - | - |
condiments / relishes: | - | - |
confectionery froastings: | - | - |
egg products: | - | - |
fats / oils: | - | - |
fish products: | - | - |
frozen dairy: | - | 16.00000 |
fruit ices: | - | 16.00000 |
gelatins / puddings: | - | 15.00000 |
granulated sugar: | - | - |
gravies: | - | - |
hard candy: | - | 16.00000 |
imitation dairy: | - | - |
instant coffee / tea: | - | - |
jams / jellies: | - | - |
meat products: | - | - |
milk products: | - | - |
nut products: | - | - |
other grains: | - | - |
poultry: | - | - |
processed fruits: | - | - |
processed vegetables: | - | - |
reconstituted vegetables: | - | - |
seasonings / flavors: | - | - |
snack foods: | - | - |
soft candy: | - | - |
soups: | - | - |
sugar substitutes: | - | - |
sweet sauces: | - | - |
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s): |
The FEMA GRAS assessment of lactones used as flavor ingredients.View pdf |
European Food Safety Athority(efsa): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf |
Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 View page or View pdf |
EPI System: | View |
Env. Mutagen Info. Center: | Search |
EPA Substance Registry Services (TSCA): | 104-50-7 |
EPA ACToR: | Toxicology Data |
EPA Substance Registry Services (SRS): | Registry |
Laboratory Chemical Safety Summary : | 7704 |
National Institute of Allergy and Infectious Diseases: | Data |
WGK Germany: | 1 |
| 5-butyloxolan-2-one |
Chemidplus: | 0000104507 |
RTECS: | LU3562000 for cas# 104-50-7 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
5- | butyl dihydro-2(3H)-furanone | 5- | butyl tetrahydro-2-furanone | 4- | butyl-4-hydroxybutyric acid lactone | 4-N- | butyl-4-hydroxybutyric acid lactone | 4- | butyl-gamma-butyrolactone | gamma- | butyl-gamma-butyrolactone | gamma-N- | butyl-gamma-butyrolactone | 5- | butyldihydro-2(3H)-furanone | 5- | butyldihydrofuran-2(3H)-one | 5- | butyloxolan-2-one | 2(3H)- | furanone, 5-butyldihydro- | 2(3H)- | furanone, dihydro-5-butyl- | 4- | hydroxyoctanoic acid gamma-lactone | 4- | hydroxyoctanoic acid lactone | gamma- | octa lactone | g- | octalactone | gamma | octalactone | gamma- | octalactone FCC | | octalactone gamma | g- | octalactone natural | gamma- | octalactone natural | gamma- | octalactone, natural | | octan-4-olide | | octano-1,4-lactone | | octanoic acid gamma lactone | | octanoic acid, 4-hydroxy-, lactone | gamma- | octanolactone | 4- | octanolide | | octanolide-1,4 |
Articles:
PubMed: | Specific Volatile Compounds from Mango Elicit Oviposition in Gravid Bactrocera dorsalis Females. |
PubMed: | Oviposition site-selection by Bactrocera dorsalis is mediated through an innate recognition template tuned to γ-Octalactone. |
PubMed: | 6-Pentyl-2H-pyran-2-one: a potent peach-derived kairomone for New Zealand flower thrips, Thrips obscuratus. |
PubMed: | Effect of α-tocopherol on lactone formation in marbled beef and changes in lactone volatility during storage. |
PubMed: | Isolation and identification of host cues from mango, Mangifera indica, that attract gravid female oriental fruit fly, Bactrocera dorsalis. |
PubMed: | Artificial aging of Uva di Troia and Primitivo wines using oak chips inoculated with Penicillium purpurogenum. |
PubMed: | Effects of alpha-tocopherol on lactones in beef headspace during storage. |
PubMed: | Use of microfungi in the treatment of oak chips: possible effects on wine. |
PubMed: | Expression of genes associated with aroma formation derived from the fatty acid pathway during peach fruit ripening. |
PubMed: | Fate of key odorants in Sauternes wines through aging. |
PubMed: | Comparison of urinary scents of two related mouse species, Mus spicilegus and Mus domesticus. |
PubMed: | Volatile compounds in acacia, chestnut, cherry, ash, and oak woods, with a view to their use in cooperage. |
PubMed: | Odor detection thresholds and enantiomeric distributions of several 4-alkyl substituted gamma-lactones in Australian red wine. |
PubMed: | Quantification of several 4-alkyl substituted gamma-lactones in Australian wines. |
PubMed: | Effect of grain type and toasting conditions of barrels on the concentration of the volatile substances released by the wood and on the sensory characteristics of Montepulciano d'Abruzzo. |
PubMed: | Aroma extraction dilution analysis of Sauternes wines. Key role of polyfunctional thiols. |
PubMed: | Aroma composition of red wines by different extraction methods and Gas Chromatography-SIM/MASS spectrometry analysis. |
PubMed: | Effect of fat nature and aroma compound hydrophobicity on flavor release from complex food emulsions. |
PubMed: | Composition rather than viscosity modifies the aroma compound retention of flavored stirred yogurt. |
PubMed: | Volatile compounds in a spanish red wine aged in barrels made of Spanish, French, and American oak wood. |
PubMed: | Influence of distillation system, oak wood type, and aging time on volatile compounds of cider brandy. |
PubMed: | Identification of aroma active compounds in orange essence oil using gas chromatography-olfactometry and gas chromatography-mass spectrometry. |
PubMed: | Prediction of aged red wine aroma properties from aroma chemical composition. Partial least squares regression models. |
PubMed: | Comparison of direct and indirect methods of measuring the precursors of beta-methyl-gamma-octalactone and their application to the analysis of Sessile oak wood. |
PubMed: | Identification of a precursor of beta-methyl-gamma-octalactone in the wood of sessile oak (Quercus petraea (Matt.) Liebl.). |
PubMed: | Influence of storage conditions on the formation of some volatile compounds in white fortified wines (Vins doux naturels) during the aging process. |
PubMed: | Chirality of the gamma-lactones produced by Sporidiobolus salmonicolor grown in two different media. |
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