| Name: | 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione |
| CAS Number: | 303-98-0 |  3D/inchi
|
| Other(deleted CASRN): | 13448-14-1 |
| FDA UNII: | EJ27X76M46 |
| Nikkaji Web: | J11.405G |
| Beilstein Number: | 1900141 |
| MDL: | MFCD00042919 |
| XlogP3-AA: | 19.40 (est) |
| Molecular Weight: | 863.36310000 |
| Formula: | C59 H90 O4 |
| BioActivity Summary: | listing |
| NMR Predictor: | Predict (works with chrome, Edge or firefox) |
Category:nutrient adjuncts, dietary supplements, nutrient agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | yellow to orange crystalline powder (est) |
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 49.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 868.00 to 869.00 °C. @ 760.00 mm Hg (est)
|
| Flash Point: | 616.00 °F. TCC ( 324.60 °C. ) (est)
|
| logP (o/w): | 19.119 (est) |
| Soluble in: |
| | water, 5.234e-013 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
| AIDP |
| Co-Q10 – Chinese Fermented 98% - 101%
|
| AIDP |
| Co-Q10 – Japanese 98%-101%
|
| Allied Biotech |
| Coenzyme Q10
Odor: characteristic Use: In most people over 30, levels of CoQ10 in the skin are below optimum, resulting in reduced ability to produce collagen, elastin, and other important skin molecules. CoQ10 depleted skin may be more prone to damage by free radicals. CoQ10 may boost skin repair and regeneration and reduce free radical damage. |
| Allied Biotech |
| NanoQ 10% FT
Flavor: characteristic is an emulsion, which has made use of Allied Biotech's proprietary formulation technology to produce solubilised nano grade material. NanoQ has a mean particle size of less than 200 nm, which compared to the crystalline material that is found in most competitive products, has approximately 70 times the surface area that can come in contact with the digestive system.NanoQ 10% FT is typically used in nutritional beverages where it disperses and creates a clear liquid. |
| Allied Biotech |
| NanoQ 10% HB
Flavor: characteristic is a powder based version of Co-enzyme Q10, which uses Allied Biotech's proprietary formulation technology to produce solubilised nano grade material.NanoQ 10% HB is typically used in innovative food products and nutritional beverages where it disperses and creates a clear liquid. |
| American International Chemical, LLC. |
| CoEnzyme Q 10 USP 10%, 20%, 40% WS powders
|
| AuNutra® Industries |
| Coenzyme Q10
|
| BOC Sciences |
| For experimental / research use only. |
| Coenzyme Q10 >98%
Odor: characteristic Use: Coenzyme Q10 (ubiquinone, ubidecarenone, coenzyme Q) is a component of the electron transport chain and participates in aerobic cellular respiration. |
| Charkit Chemical |
| COENZYME Q10
|
| Coompo |
| For experimental / research use only. |
| Coenzyme Q10 from Plants ≥98%
|
| DSM Nutritional |
| ALL-Q™
|
| Farbest-Tallman Foods |
| ZMC Coenzyme Q10 10% CWS
Flavor: bland Used in food and dietary supplement applications for health claims including heart and brain health. |
| Farbest-Tallman Foods |
| ZMC Coenzyme Q10 100% USP/EP
Flavor: bland Applications include dietary supplements including hard shell capsules and tablets. |
| Farbest-Tallman Foods |
| ZMC Coenzyme Q10 20% CWS
Flavor: bland Used in food and dietary supplement applications for health claims including heart and brain health. |
| George Uhe Company |
| Coenzyme Q
|
| Glentham Life Sciences |
| Coenzyme Q10
|
| Jiangyin Healthway |
| Ubidecarenone ( Coenzyme Q10)
|
| New functional food ingredients |
| Maypro Industries |
| Ubidecarenone (Coenzyme Q-10)
|
| Meafo |
| For experimental / research use only. |
| Coenzyme Q10
|
| Qingdao Dacon Trading |
| Coenzyme Q10
|
| Shaanxi Y-Herb Biotechnology |
| Q10 Monomer Powder USP Grade Ubiquinone Coenzyme 10% 98% 99% CAS 303-98-0 Co Q10
|
| Sigma-Aldrich |
| For experimental / research use only. |
| Coenzyme Q10 analytical standard
|
| TRI-K Industries |
| Nano-Lipobelle DN CoQ10 oA
Odor: characteristic Use: Nano-Lipobelle DN CoQ10 contains ultra small particles of coenzyme Q10 that grant a fast penetration in deeper skin layers. |
| TRI-K Industries |
| Nano-Lipobelle H-AECL
Odor: characteristic Use: Nano-Lipobelle H-AECL is a nano-emulsion loaded with vitamins A, E, C and borage oil. |
| TRI-K Industries |
| Nano-Lipobelle H-EQ10
Odor: characteristic Use: Nano-Lipobelle H-EQ10 is a nano-emulsion of well characterized nanoparticles. Their oil cores are stabilized by highly purified soy phospholipids and are loaded with vitamin E and Coenzyme Q10. |
| TRI-K Industries |
| Nano-Lipobelle t-EQ10
Odor: characteristic Use: Nano-Lipobelle t-EQ10 is a translucent nano-emulsion of well characterized particles. Their oil cores are stabilized by highly purified soy phospholipids and are loaded with vitamin E and Coenzyme Q10. |
| TRI-K Industries |
| Nano-Lipobelle t-UV
Odor: characteristic Use: Nano-Lipobelle t-UV is a cationic nano-emulsion loaded with UVA and UVB filters. Specifically designed for hair, it protects against daily environmental stress, notably sun. |
| TRI-K Industries |
| Nano-Lipobelle UV-A/B
Odor: characteristic Use: Nano-Lipobelle UV-A/B is a cationic nano-emulsion of well characterized particles. Their oil cores are stabilized by highly purified soy phospholipids and are loaded with UV filters. |
| United International |
| Q10 Coenzyme
|
| WILD Flavors |
| Coenzyme Q10
Flavor: taste Coenzyme Q10 (Co-Q10) is a very powerful antioxidant with diverse health benefits. It is essential for body cells, tissues, and organs (including the heart) and is also needed for energy production. |
| Xi'an Greena Biotech |
| Coenzyme Q10
Odor: characteristic Use: CoQ10 or Coenzyme Q10 is an antioxidant that is made in the human body ,and it is a powerful antioxidant.
Antioxidants fight damaging particles in the body known as free radicals, which damage cell membranes, tamper with DNA, and even cause cell death. Scientists believe free radicals contribute to the aging process, as well as a number of health problems, including heart disease and cancer. Antioxidants, such as CoQ10, can neutralize free radicals and may reduce or even help prevent some of the damage they cause.
Some researchers believe that CoQ10 may help with heart-related conditions, because it can improve energy production in cells, prevent blood clot formation, and act as an antioxidant. |
| Zanos |
| Coenzyme Q10
|
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intramuscular-mouse LD > 500 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972.
intravenous-mouse LD > 500 mg/kg
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972.
oral-mouse LD > 4000 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972.
intramuscular-rat LD > 500 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972.
intravenous-rat LD > 250 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972.
oral-rat LD > 4000 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972.
|
| Dermal Toxicity: |
subcutaneous-mouse LD > 500 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972.
subcutaneous-rat LD > 500 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 769, 1972.
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | nutrient adjuncts, dietary supplements, nutrient agents |
| Recommendation for ubidecarenone usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for ubidecarenone flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
| EPI System: View |
| ClinicalTrials.gov:search |
| Daily Med:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):303-98-0 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :5281915 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione |
| Chemidplus:0000303980 |
| RTECS:DK3900000 for cas# 303-98-0 |
References:
| | 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5281915 |
| Pubchem (sid): | 135021917 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | adelir | | | ALL-Q | | | bio-quinon | | | co-enzyme Q-10 | | | Co-Q10 – chinese fermented 98% - 101% | | | Co-Q10 – japanese 98%-101% | | | coenzyme Q | | | coenzyme Q 10 | | | coenzyme Q10 | | 2-((all-E)-3,7,11,15,19,23,27,31,35,39- | decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl)-5,6-dimethoxy-3-methyl-p-benzoquinone | | 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39- | decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione | | | emitolon | | | ensorb | | | heartcin | | | inokiten | | | justquinon | | | luvacor | | | mitoquinone | | | nanoQ 10% FT | | | nanoQ 10% HB | | | neuquinone | | | terekol | | | ube-Q | | | ubidecarenona | | | ubidecarenonum | | | ubiquinone | | | ubisemiquinone | | | udekinon | | | ZMC coenzyme Q10 10% CWS | | | ZMC coenzyme Q10 100% USP/EP | | | ZMC coenzyme Q10 20% CWS |
Articles:
| PubMed:Long-term Effect of Ubiquinol on Exercise Capacity and the Oxidative Stress Regulation System in SAMP1 Mice. |
| PubMed:Coenzyme Q10 Promotes Macrophage Cholesterol Efflux by Regulation of the Activator Protein-1/MicroRNA-378/ATP-Binding Cassette Transporter G1-Signaling Pathway. |
| PubMed:Factors Influencing the Contents of Coenzyme Q10 and Q9 in Olive Oils. |
| PubMed:Droplet size and composition of nutraceutical nanoemulsions influences bioavailability of long chain fatty acids and Coenzyme Q10. |
| PubMed:Nitrogen-bisphosphonate therapy is linked to compromised coenzyme q10 and vitamin e status in postmenopausal women. |
| PubMed:Rapid determination of coenzyme Q10 in food supplements using 1H NMR spectroscopy. |
| PubMed:Effect of onion peel extract supplementation on the lipid profile and antioxidative status of healthy young women: a randomized, placebo-controlled, double-blind, crossover trial. |
| PubMed:Coenzyme Q10 production in plants: current status and future prospects. |
| PubMed:Comprehensive rehabilitation in chronic heart failure. |
| PubMed:Nutritional recommendations for cardiovascular disease prevention. |
| PubMed:Chronic treatment with coenzyme Q10 reverses restraint stress-induced anhedonia and enhances brain mitochondrial respiratory chain and creatine kinase activities in rats. |
| PubMed:Encapsulation of coenzyme Q10 in a simple emulsion-based nutraceutical formulation and application in cheese manufacturing. |
| PubMed:A combined natural supplement lowers LDL cholesterol in subjects with moderate untreated hypercholesterolemia: a randomized placebo-controlled trial. |
| PubMed:Food, nutrigenomics, and neurodegeneration--neuroprotection by what you eat! |
| PubMed:Loktanella sediminilitoris sp. nov., isolated from tidal flat sediment. |
| PubMed:Enhanced water dispersibility of coenzyme Q10 by complexation with albumin hydrolysate. |
| PubMed:Variability in the contents of pork meat nutrients and how it may affect food composition databases. |
| PubMed:Coenzyme q10 regulates osteoclast and osteoblast differentiation. |
| PubMed:Analytical problems with the determination of coenzyme Q10 in biological samples. |
| PubMed:Increased ubiquinone concentration after intracerebroventricularly-administered ubiquinol to selected rat brain regions. |
| PubMed:[Prodiabetic effect of statins--do we know the mechanisms of this phenomenon?]. |
| PubMed:Coenzyme Q10 inhibits the release of glutamate in rat cerebrocortical nerve terminals by suppression of voltage-dependent calcium influx and mitogen-activated protein kinase signaling pathway. |
| PubMed:Improvement of coenzyme Q10 production: mutagenesis induced by high hydrostatic pressure treatment and optimization of fermentation conditions. |
| PubMed:Use of a lipid-lowering food supplement in patients on hormone therapy following breast cancer. |
| PubMed:Incorporation of coenzyme Q10 into bovine oocytes improves mitochondrial features and alleviates the effects of summer thermal stress on developmental competence. |
| PubMed:Biofortification of plants with altered antioxidant content and composition: genetic engineering strategies. |
| PubMed:Inhibition of β-carotene degradation in oil-in-water nanoemulsions: influence of oil-soluble and water-soluble antioxidants. |
| PubMed:Nutritional pork meat compounds as affected by ham dry-curing. |
| PubMed:Hirschia litorea sp. nov., isolated from seashore sediment, and emended description of the genus Hirschia. |
| PubMed:Simple and fast HPLC method for simultaneous determination of retinol, tocopherols, coenzyme Q(10) and carotenoids in complex samples. |
| PubMed:The heart speaks II: embracing integrative medicine for heart health. |
| PubMed:Optimized rapeseed oil enriched with healthy micronutrients: a relevant nutritional approach to prevent cardiovascular diseases. Results of the Optim'Oils randomized intervention trial. |
| PubMed:A combination of lipoic acid plus coenzyme Q10 induces PGC1α, a master switch of energy metabolism, improves stress response, and increases cellular glutathione levels in cultured C2C12 skeletal muscle cells. |
| PubMed:Loktanella litorea sp. nov., isolated from seawater. |
| PubMed:Association of colony morphology with coenzyme Q(10) production and its enhancement from Rhizobium radiobacter T6102W by addition of isopentenyl alcohol as a precursor. |
| PubMed:Does consumption of two portions of salmon per week enhance the antioxidant defense system in pregnant women? |
| PubMed:[Effect of coenzyme Q10 supplementation on apoptosis, free radical oxidative processes and proteome pool of microsomal and cytosol fractions of hepatocytes using food ration with different lipid component]. |
| PubMed:Development of a protocol for supercritical carbon dioxide extraction of ubiquinone-10 from dried biomass of Pseudomonas diminuta. |
| PubMed:Determination of coenzyme Q10, coenzyme Q9, and melatonin contents in virgin argan oils: comparison with other edible vegetable oils. |
| PubMed:Dysmorphological and pharmacological studies in 4q- syndrome. |
| PubMed:The role of nutraceuticals in anti-aging medicine. |
| PubMed:Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway. |
| PubMed:Analysis of CoQ10 in cultivated tobacco by a high-performance liquid chromatography-ultraviolet method. |
| PubMed:Association between genetic variants in the Coenzyme Q10 metabolism and Coenzyme Q10 status in humans. |
| PubMed:Release of lipophilic molecules during in vitro digestion of soy protein-stabilized emulsions. |
| PubMed:Oxidative stress in dog with heart failure: the role of dietary Fatty acids and antioxidants. |
| PubMed:Coenzyme Q plays opposing roles on bacteria/fungi and viruses in Drosophila innate immunity. |
| PubMed:Solanesol: added value from Solanaceous waste. |
| PubMed:Effects of coenzyme Q10 on arterial stiffness, metabolic parameters, and fatigue in obese subjects: a double-blind randomized controlled study. |
| PubMed:The reduced form of coenzyme Q10 decreases the expression of lipopolysaccharide-sensitive genes in human THP-1 cells. |
| PubMed:Effects of cell lysis treatments on the yield of coenzyme Q10 following Agrobacterium tumefaciens fermentation. |
| PubMed:Age-related changes in brain mitochondrial DNA deletion and oxidative stress are differentially modulated by dietary fat type and coenzyme Q₁₀. |
| PubMed:The reduced form of coenzyme Q10 mediates distinct effects on cholesterol metabolism at the transcriptional and metabolite level in SAMP1 mice. |
| PubMed:Preservation of micronutrients during rapeseed oil refining: a tool to optimize the health value of edible vegetable oils? Rationale and design of the Optim'Oils randomized clinical trial. |
| PubMed:Coenzyme Q10: a novel gastroprotective effect via modulation of vascular permeability, prostaglandin E₂, nitric oxide and redox status in indomethacin-induced gastric ulcer model. |
| PubMed:Birth weight was negatively correlated with plasma ghrelin, insulin resistance, and coenzyme Q10 levels in overweight children. |
| PubMed:Acquired coenzyme Q10 deficiency in children with recurrent food intolerance and allergies. |
| PubMed:How Safe are Antioxidant Food Supplements Containing Selenium? |
| PubMed:Quality characteristics and composition of the longissimus muscle in the short-loin from male and female farmed red deer in New Zealand. |
| PubMed:Tobacco biomass hydrolysate enhances coenzyme Q10 production using photosynthetic Rhodospirillum rubrum. |
| PubMed:Plasma levels of vitamins A and E, coenzyme Q10, and anti-ox-LDL antibody titer in children treated with an elimination diet due to food hypersensitivity. |
| PubMed:Coenzyme Q10 attenuated DMH-induced precancerous lesions in SD rats. |
| PubMed:Emulsification of coenzyme Q10 using gum arabic increases bioavailability in rats and human and improves food-processing suitability. |
| PubMed:Coenzyme Q10 contents in foods and fortification strategies. |
| PubMed:Nanoparticulate carriers (NPC) for oral pharmaceutics and nutraceutics. |
| PubMed:Support of drug therapy using functional foods and dietary supplements: focus on statin therapy. |
| PubMed:Coenzyme Q10 production in a 150-l reactor by a mutant strain of Rhodobacter sphaeroides. |
| PubMed:Effect of Complexation Cyclodextrins with Phenolic Acids and Coenzyme Q10 on their Physico-Chemical Properties and Bioavailability. |
| PubMed:Effects of coenzyme Q10 supplementation on plasma adiponectin, interleukin-6, and tumor necrosis factor-alpha levels in men. |
| PubMed:Antifatigue effect of coenzyme Q10 in mice. |
| PubMed:Treatment of cyclic vomiting syndrome with co-enzyme Q10 and amitriptyline, a retrospective study. |
| PubMed:Development of coenzyme Q10-enriched rice using sugary and shrunken mutants. |
| PubMed:Plasma levels of insulin-like growth factor-I, insulin-like growth factor binding protein-1, coenzyme Q10 and vitamin E in female populations from Poland, Serbia and Sweden. |
| PubMed:Supplementation with the reduced form of Coenzyme Q10 decelerates phenotypic characteristics of senescence and induces a peroxisome proliferator-activated receptor-alpha gene expression signature in SAMP1 mice. |
| PubMed:Evaluation of the antioxidant effect of a new functional food enriched with Sideritis euboea in healthy subjects. |
| PubMed:Effect of beer consumption on levels of complex I and complex IV liver and heart mitochondrial enzymes and coenzymes Q9 and Q10 in adriamycin-treated rats. |
| PubMed:Recovery of solanesol from tobacco as a value-added byproduct for alternative applications. |
| PubMed:Nanoliposomes mediate coenzyme Q10 transport and accumulation across human intestinal Caco-2 cell monolayer. |
| PubMed:Gingival vascular damage in atherosclerotic rabbits: hydroxytyrosol and squalene benefits. |
| PubMed:Biosynthesis and bioproduction of coenzyme Q10 by yeasts and other organisms. |
| PubMed:Foods and supplements in the management of migraine headaches. |
| PubMed:Increasing CoQ10 production by Rhodopseudomonas palustris J001 using a two-stage fermentation process. |
| PubMed:In Vitro Effects of the Reduced Form of Coenzyme Q(10) on Secretion Levels of TNF-alpha and Chemokines in Response to LPS in the Human Monocytic Cell Line THP-1. |
| PubMed:Oxidative stress status in liver mitochondria and lymphocyte DNA damage of atherosclerotic rabbits supplemented with water soluble coenzyme Q10. |
| PubMed:Blood CoQ10 levels and safety profile after single-dose or chronic administration of PureSorb-Q40: animal and human studies. |
| PubMed:Safety assessment of coenzyme Q10 (CoQ10). |
| PubMed:Functions of coenzyme Q10 in inflammation and gene expression. |
| PubMed:Influence of Coenzyme Q_{10} on release of pro-inflammatory chemokines in the human monocytic cell line THP-1. |
| PubMed:Acute, subacute toxicity and genotoxic effect of Bio-Quinone Q10 in mice and rats. |
| PubMed:Effects of Coenzyme Q10 on TNF-alpha secretion in human and murine monocytic cell lines. |
| PubMed:Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77). |
| PubMed:Coenzyme Q10: is there a clinical role and a case for measurement? |
| PubMed:Physicochemical and pharmacokinetic characterization of water-soluble Coenzyme Q(10) formulations. |
| PubMed:Interaction of coenzyme Q10 with the intestinal drug transporter P-glycoprotein. |
| PubMed:[Effects of coenzyme Q10 or combined with micronutrients on antioxidant defense system in rats]. |
| PubMed:Relative bioavailability of two forms of a novel water-soluble coenzyme Q10. |
| PubMed:Determination of coenzyme Q10 and Q9 in vegetable oils. |
| PubMed:Coenzyme Q9 provides cardioprotection after converting into coenzyme Q10. |
| PubMed:Coenzyme Q10 administration suppresses both oxidative and antioxidative markers in hemodialysis patients. |
| PubMed:Subchronic oral toxicity of ubiquinol in rats and dogs. |
| PubMed:Toxicity of coenzyme Q(10): a report of 90-day repeated dose toxicity study in rats. |
| PubMed:Effects of decylubiquinone (coenzyme Q10 analog) supplementation on SHRSP. |
| PubMed:The quality control assessment of commercially available coenzyme q(10)-containing dietary and health supplements in Japan. |
| PubMed:Increase of bioavailability of coenzyme Q(10) and vitamin E. |
| PubMed:Nonvitamin, nonmineral dietary supplementation in HIV-positive people. |
| PubMed:Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction. |
| PubMed:Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism. |
| PubMed:Thirteen-week repeated dose oral toxicity study of coenzyme Q10 in rats. |
| PubMed:Functional connections and pathways of coenzyme Q10-inducible genes: an in-silico study. |
| PubMed:[Effect of biologically active food supplement coenzyme Q10 on metabolic processes in the myocardium of rats kept in different temperature conditions]. |
| PubMed:Improvement in intestinal coenzyme q10 absorption by food intake. |
| PubMed:Comparison of uptake between PureSorb-Q40 and regular hydrophobic coenzyme Q10 in rats and humans after single oral intake. |
| PubMed:Effect of coenzyme Q(10) incorporation on the characteristics of nanoliposomes. |
| PubMed:Nutrition and herbs. Cholesterol drug side effects may be linked to low nutrient levels. |
| PubMed:Effect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats. |
| PubMed:Critical assessment of various techniques for the extraction of carotenoids and co-enzyme Q10 from the Thraustochytrid strain ONC-T18. |
| PubMed:The cosmetic treatment of wrinkles. |
| PubMed:Comparison of the relative bioavailability of different coenzyme Q10 formulations with a novel solubilizate (Solu Q10). |
| PubMed:[Case of drug-induced pneumonitis associated with a dietary supplement containing CoQ10]. |
| PubMed:Optimization in the preparation of coenzyme Q10 nanoliposomes. |
| PubMed:Life-long supplementation with a low dosage of coenzyme Q10 in the rat: effects on antioxidant status and DNA damage. |
| PubMed:Coenzyme Q10 in maternal plasma and milk throughout early lactation. |
| PubMed:Neuroprotective agents for clinical trials in ALS: a systematic assessment. |
| PubMed:Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective. |
| PubMed:HPLC method for simultaneous determination of retinol, alpha-tocopherol and coenzyme Q10 in human plasma. |
| PubMed:[The influence of phospholipids food and antioxidant at patients with hypertension]. |
| PubMed:[The role of antioxidants in prevention]. |
| PubMed:On the bioequivalence and bioavailability of three coenzyme Q10 products. |
| PubMed:Cryptococcus bestiolae and Cryptococcus dejecticola, two new yeast species isolated from frass of the litchi fruit borer Conopomorpha sinensis Bradley. |
| PubMed:Aging and antioxidants. Fruits and vegetables are powerful armor. |
| PubMed:Metabolic engineering of coenzyme Q by modification of isoprenoid side chain in plant. |
| PubMed:Coenzyme Q concentration and total antioxidant capacity of human milk at different stages of lactation in mothers of preterm and full-term infants. |
| PubMed:Dietary antioxidants in preventing atherogenesis. |
| PubMed:Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease. |
| PubMed:Evaluation of the mutagenic potential of ubidecarenone using three short-term assays. |
| PubMed:A new Coenzyme Q10 tablet-grade formulation (all-Q) is bioequivalent to Q-Gel and both have better bioavailability properties than Q-SorB. |
| PubMed:Quantitative determination of coenyzme Q10 by liquid chromatography and liquid chromatography/mass spectrometry in dairy products. |
| PubMed:Age-associated changes in protein oxidation and proteasome activities in rat brain: modulation by antioxidants. |
| PubMed:Coenzyme Q10 protects from aging-related oxidative stress and improves mitochondrial function in heart of rats fed a polyunsaturated fatty acid (PUFA)-rich diet. |
| PubMed:Selenium and antioxidant vitamin status of elderly German women. |
| PubMed:Cognitive performance in relation to vitamin status in healthy elderly German women-the effect of 6-month multivitamin supplementation. |
| PubMed:Maternal antioxidant supplementation does not reduce the incidence of phenytoin-induced cleft lip and related malformations in rats. |
| PubMed:The role of antioxidant micronutrients in the prevention of diabetic complications. |
| PubMed:Changes in antioxidant status of myocardium during oxidative stress under the influence of coenzyme Q10. |
| PubMed:28-Day repeated dose toxicity study of dried microorganism in rats. |
| PubMed:Simultaneous analysis of coenzyme Q10 in plasma, erythrocytes and platelets: comparison of the antioxidant level in blood cells and their environment in healthy children and after oral supplementation in adults. |
| PubMed:Coenzyme Q differentially modulates phospholipid hydroperoxide glutathione peroxidase gene expression and free radicals production in malignant and non-malignant prostate cells. |
| PubMed:[Effect of coenzyme Q10 on free radical centers in isolated rat myocardium tissue]. |
| PubMed:Plasma ubiquinone status and response to six-month supplementation combined with multivitamins in healthy elderly women--results of a randomized, double-blind, placebo-controlled study. |
| PubMed:Attenuation of blood parameters in smokers and non-smokers after intake of a complex food additive. |
| PubMed:Efficacy of over-the-counter nutritional supplements. |
| PubMed:How to re-energise old mitochondria without shooting yourself in the foot. |
| PubMed:Use of alternative pharmacotherapy in management of cardiovascular diseases. |
| PubMed:Lipid-lowering drugs (statins), cholesterol, and coenzyme Q10. The Baycol case--a modern Pandora's box. |
| PubMed:Current concepts in optimum nutrition for cardiovascular disease. |
| PubMed:Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress. |
| PubMed:Extra co-enzyme Q10 for statin-users? |
| PubMed:Hepatothermic therapy of obesity: rationale and an inventory of resources. |
| PubMed:In vitro test for the effectiveness of antioxidants as inhibitors of thiyl radical-induced reactions with unsaturated fatty acids. |
| PubMed:Dietary coenzyme Q10 and vitamin E alter the status of these compounds in rat tissues and mitochondria. |
| PubMed:[Coenzyme Q10--its importance, properties and use in nutrition and cosmetics]. |
| PubMed:Toward a wholly nutritional therapy for type 2 diabetes. |
| PubMed:Comparison of in-line connected diode array and electrochemical detectors in the high-performance liquid chromatographic analysis of coenzymes Q(9) and Q(10) in food materials. |
| PubMed:Plasma coenzyme Q10 concentrations are not decreased in male patients with coronary atherosclerosis. |
| PubMed:Oral reduced B-nicotinamide adenine dinucleotide (NADH) affects blood pressure, lipid peroxidation, and lipid profile in hypertensive rats (SHR). |
| PubMed:Recent nutritional approaches to the prevention and therapy of cardiovascular disease. |
| PubMed:Coenzyme Q10 in the diet--daily intake and relative bioavailability. |
| PubMed:Dietary restriction affects antioxidant levels in rat liver mitochondria during ageing. |
| PubMed:Lipid peroxidation and antioxidants in newborns. |
| PubMed:The effect of ethanol and/or food restriction on coenzyme Q in liver in rats. |
| PubMed:Coenzyme Q content depends upon oxidative stress and dietary fat unsaturation. |
| PubMed:The coenzyme Q10 content of the average Danish diet. |
| PubMed:Dietary coenzyme Q10 supplementation alters platelet size and inhibits human vitronectin (CD51/CD61) receptor expression. |
| PubMed:Multiple antioxidants protect against heme protein and lipid oxidation in kidney tissue. |
| PubMed:Vitamin E, selenium, trolox C, ascorbic acid palmitate, acetylcysteine, coenzyme Q, beta-carotene, canthaxanthin, and (+)-catechin protect against oxidative damage to kidney, heart, lung and spleen. |
| PubMed:Protection by vitamin E selenium, trolox C, ascorbic acid palmitate, acetylcysteine, coenzyme Q, beta-carotene, canthaxanthin, and (+)-catechin against oxidative damage to liver slices measured by oxidized heme proteins. |
| PubMed:Effects of ethanol, lovastatin and coenzyme Q10 treatment on antioxidants and TBA reactive material in liver of rats. |
| PubMed:Comparative antioxidant effectiveness of dietary beta-carotene, vitamin E, selenium and coenzyme Q10 in rat erythrocytes and plasma. |
| PubMed:Dietary supplements of vitamin E, beta-carotene, coenzyme Q10 and selenium protect tissues against lipid peroxidation in rat tissue slices. |
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