apo-lactoferrin

Articles:

PubMed:A Moraxella catarrhalis two-component signal transduction system necessary for growth in liquid media affects production of two lysozyme inhibitors.

PubMed:The structure of lactoferrin-binding protein B from Neisseria meningitidis suggests roles in iron acquisition and neutralization of host defences.

PubMed:Identification of unprecedented anticancer properties of high molecular weight biomacromolecular complex containing bovine lactoferrin (HMW-bLf).

PubMed:Effect of bovine apo-lactoferrin on the growth and virulence of Actinobacillus pleuropneumoniae.

PubMed:Structure of the iron-free true C-terminal half of bovine lactoferrin produced by tryptic digestion and its functional significance in the gut.

PubMed:Lactoferrin directly scavenges hydroxyl radicals and undergoes oxidative self-degradation: a possible role in protection against oxidative DNA damage.

PubMed:Retention of structure, antigenicity, and biological function of pneumococcal surface protein A (PspA) released from polyanhydride nanoparticles.

PubMed:A high-throughput method for the quantification of iron saturation in lactoferrin preparations.

PubMed:Selenium compound protects corneal epithelium against oxidative stress.

PubMed:Human apo-lactoferrin as a physiological mimetic of hypoxia stabilizes hypoxia-inducible factor-1 alpha.

PubMed:The transfer of iron between ceruloplasmin and transferrins.

PubMed:Apo- and holo-lactoferrin stimulate proliferation of mouse crypt cells but through different cellular signaling pathways.

PubMed:Apo- and holo-lactoferrin are both internalized by lactoferrin receptor via clathrin-mediated endocytosis but differentially affect ERK-signaling and cell proliferation in Caco-2 cells.

PubMed:Lactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events.

PubMed:Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.

PubMed:Effect of apolactoferrin on experimental pneumococcal otitis media.

PubMed:Effect of bovine lactoferrin addition to milk in yogurt manufacturing.

PubMed:Use and endocytosis of iron-containing proteins by Entamoeba histolytica trophozoites.

PubMed:28-Day repeated dose oral toxicity of recombinant human apo-lactoferrin or recombinant human lysozyme in rats.

PubMed:IsdA protects Staphylococcus aureus against the bactericidal protease activity of apolactoferrin.

PubMed:Thiophilic interaction chromatography of mammalian and avian transferrins.

PubMed:Apolactoferrin inhibits the catalytic domain of matrix metalloproteinase-2 by zinc chelation.

PubMed:Amoebicidal activity of milk, apo-lactoferrin, sIgA and lysozyme.

PubMed:Capsule does not block antibody binding to PspA, a surface virulence protein of Streptococcus pneumoniae.

PubMed:Human hololactoferrin: endocytosis and use as an iron source by the parasite Entamoeba histolytica.

PubMed:PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin [corrected].

PubMed:Growth-promoting effects of lactoferrin on L. acidophilus and Bifidobacterium spp.

PubMed:Lactoferrin and iron: structural and dynamic aspects of binding and release.

PubMed:Human apo-lactoferrin enhances angiogenesis mediated by vascular endothelial growth factor A in vivo.

PubMed:In vivo effects of bifidobacteria and lactoferrin on gut endotoxin concentration and mucosal immunity in Balb/c mice.

PubMed:Tertiary structural changes associated with iron binding and release in hen serum transferrin: a crystallographic and spectroscopic study.

PubMed:In vitro growth responses of bifidobacteria and enteropathogens to bovine and human lactoferrin.

PubMed:In vitro characterization of lactoferrin aggregation and amyloid formation.

PubMed:Lactoferrin in the preterm infants' diet attenuates iron-induced oxidation products.

PubMed:Lactoferrin iron levels affect attachment of Actinobacillus actinomycetemcomitans to buccal epithelial cells.

PubMed:Crystal structure of equine apolactoferrin at 303 K providing further evidence of closed conformations of N and C lobes.

PubMed:Involvement of bovine lactoferrin metal saturation, sialic acid and protein fragments in the inhibition of rotavirus infection.

PubMed:Protein intermediate trapped by the simultaneous crystallization process. Crystal structure of an iron-saturated intermediate in the Fe3+ binding pathway of camel lactoferrin at 2.7 a resolution.

PubMed:Camel lactoferrin, a transferrin-cum-lactoferrin: crystal structure of camel apolactoferrin at 2.6 A resolution and structural basis of its dual role.

PubMed:Inhibitory effect of lactoferrin on the adhesion of Prevotella nigrescens ATCC 25261 to hydroxyapatite.

PubMed:Transferrins: iron release from lactoferrin.

PubMed:Metal complexes of lactoferrin and their effect on the intracellular multiplication of Legionella pneumophila.

PubMed:Structure of mare apolactoferrin: the N and C lobes are in the closed form.

PubMed:Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change. addendum

PubMed:Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change.

PubMed:Growth responses of coliform bacteria to purified immunoglobulin G from cows immunized with ferric enterobactin receptor FepA.

PubMed:Antiviral effect of bovine lactoferrin saturated with metal ions on early steps of human immunodeficiency virus type 1 infection.

PubMed:Bovine lactoferrin and Lactoferricin inhibit tumor metastasis in mice.

PubMed:Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin.

PubMed:Synergic antistaphylococcal properties of lactoferrin and lysozyme.

PubMed:Transferrins--a mechanism for iron uptake by lactoferrin.

PubMed:The pH-induced release of iron from transferrin investigated with a continuum electrostatic model.

PubMed:Inhibition of in vitro growth of coliform bacteria by a monoclonal antibody directed against ferric enterobactin receptor FepA.

PubMed:Antirotaviral activity of milk proteins: lactoferrin prevents rotavirus infection in the enterocyte-like cell line HT-29.

PubMed:The antifungal effect of lactoferrin and lysozyme on Candida krusei and Candida albicans.

PubMed:An estrogen inducible 104 kDa chaperone glycoprotein binds ferric iron containing proteins: a possible role in intracellular iron trafficking.

PubMed:Human lactoferrin receptor activity in non-encapsulated Haemophilus influenzae.

PubMed:Transferrin--interactions of lactoferrin with hydrogen carbonate.

PubMed:Augmented inhibition of growth of Candida albicans by neutrophils in the presence of lactoferrin.

PubMed:Relationship between antibacterial activity and cell surface binding of lactoferrin in species of genus Micrococcus.

PubMed:Bovine lactoferrin and lactoferricin, a peptide derived from bovine lactoferrin, inhibit tumor metastasis in mice.

PubMed:Lactoferrin as a suppressor of cell migration of gastrointestinal cell lines.

PubMed:Compact growth of Staphylococcus haemolyticus in soft agar is not due to hydrophobic interaction between the cocci.

PubMed:Antibacterial activity of peptides homologous to a loop region in human lactoferrin.

PubMed:Immobilized metal ion affinity chromatography.

PubMed:Growth inhibitory effects of bovine lactoferrin to Toxoplasma gondii parasites in murine somatic cells.

PubMed:Preparation of apolactoferrin with a very low iron saturation.

PubMed:Modulation of the anti-Candida activity of apo-lactoferrin by dietary sucrose and tunicamycin in vitro.

PubMed:The effect of antifungal agents on the in vitro susceptibility of Candida albicans to apo-lactoferrin.

PubMed:Acquisition of iron from transferrin and lactoferrin by the protozoan Leishmania chagasi.

PubMed:Iron-induced conformational change in human lactoferrin: demonstration by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and analysis of effects of iron binding to the N and C lobes of the molecule.

PubMed:Protein-binding Properties of two Antitumour Ru(III) Complexes to Human Apotransferrin and Apolactoferrin.

PubMed:Kinetic parameters for the heat denaturation of bovine lactoferrin in milk, and its effect on interaction with monocytes.

PubMed:A comparison of the three-dimensional structures of human lactoferrin in its iron free and iron saturated forms.

PubMed:Antimicrobial peptides of lactoferrin.

PubMed:Three-dimensional structure of lactoferrin in various functional states.

PubMed:Proposed mechanisms for the involvement of lactoferrin in the hydrolysis of nucleic acids.

PubMed:The fungicidal effect of human lactoferrin on Candida albicans and Candida krusei.

PubMed:Thermal behavior of bovine lactoferrin in water and its relation to bacterial interaction and antibacterial activity.

PubMed:Iron binding to human lactoferrin alters reactivity of the protein with plant lectins.

PubMed:Forms of lactoferrin: their antibacterial effect on enterotoxigenic Escherichia coli.

PubMed:Effect of heat treatment and other milk proteins on the interaction of lactoferrin with monocytes.

PubMed:Influence of lactoferrin on the entry process of Escherichia coli HB101 (pRI203) in HeLa cells.

PubMed:Agglutination of Streptococcus mutans serotype C cells but inhibition of Porphyromonas gingivalis autoaggregation by human lactoferrin.

PubMed:Nitric oxide interaction with lactoferrin and its production by macrophage cells studied by EPR and spin trapping.

PubMed:Preliminary crystallographic studies of the amino terminal half of human lactoferrin in its iron-saturated and iron-free forms.

PubMed:Interaction of lactoferrin and lipopolysaccharide (LPS): effects on the antioxidant property of lactoferrin and the ability of LPS to prime human neutrophils for enhanced superoxide formation.

PubMed:High-performance liquid chromatographic separation of human apolactoferrin and monoferric and diferric lactoferrins.

PubMed:Different profiles of induced cotton effects of human and bovine lactoferrin by cibacron blue F3GA binding.

PubMed:Effect of transferrin, lactoferrin and chelated iron on human T-lymphocytes.

PubMed:Apotransferrins from several species promote thyroid hormone-dependent rat pituitary tumor cell growth in iron-restricted serum-free defined culture.

PubMed:Fungicidal effect of human lactoferrin against Candida albicans.

PubMed:Uptake of lactoferrin by mononuclear phagocytes inhibits their ability to form hydroxyl radical and protects them from membrane autoperoxidation.

PubMed:Binding and endocytosis of apo- and holo-lactoferrin by isolated rat hepatocytes.

PubMed:Molecular replacement solution of the structure of apolactoferrin, a protein displaying large-scale conformational change.

PubMed:Lactoferrin inhibits or promotes Legionella pneumophila intracellular multiplication in nonactivated and interferon gamma-activated human monocytes depending upon its degree of iron saturation. Iron-lactoferrin and nonphysiologic iron chelates reverse monocyte activation against Legionella pneumophila.

PubMed:Pseudomonas and neutrophil products modify transferrin and lactoferrin to create conditions that favor hydroxyl radical formation.

PubMed:Structure, function and flexibility of human lactoferrin.

PubMed:Metal ligand-induced alterations in the surface structures of lactoferrin and transferrin probed by interaction with immobilized copper(II) ions.

PubMed:Prooxidant activity of transferrin and lactoferrin.

PubMed:Iron is not required in the lactoferrin stimulation of thymidine incorporation into the DNA of rat crypt enterocytes.

PubMed:Apolactoferrin structure demonstrates ligand-induced conformational change in transferrins.

PubMed:Differential interaction of peptides and protein surface structures with free metal ions and surface-immobilized metal ions.

PubMed:Growth of gram-negative bacteria in dry cow secretion.

PubMed:Interaction of lactoferrin with Escherichia coli cells and correlation with antibacterial activity.

PubMed:Rapid purification of porcine colostral whey lactoferrin by affinity chromatography on single-stranded DNA-agarose. Characterization, amino acid composition and N-terminal amino acid sequence.

PubMed:Interaction of human lactoferrin with DNA: one-step purification by affinity chromatography on single-stranded DNA-agarose.

PubMed:Preliminary crystallographic studies on human apo-lactoferrin in its native and deglycosylated forms.

PubMed:Growth and adsorption of Streptococcus mutans 6715-13 to hydroxyapatite in the presence of lactoferrin.

PubMed:The superoxide-dependent transfer of iron from ferritin to transferrin and lactoferrin.

PubMed:Characterization of the human transferrin and lactoferrin receptors in Haemophilus influenzae.

PubMed:Identification and characterization of the human lactoferrin-binding protein from Neisseria meningitidis.

PubMed:Susceptibilities of lactoferrin and transferrin to myeloperoxidase-dependent loss of iron-binding capacity.

PubMed:Iron metabolism in BeWo chorion carcinoma cells. Transferrin-mediated uptake and release of iron.

PubMed:Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Are lactoferrin and transferrin promoters of hydroxyl-radical generation?

PubMed:Bactericidal effect of lactoferrin on Legionella pneumophila.

PubMed:In vitro growth of mastitis-associated streptococci in bovine mammary secretions.

PubMed:Effect of iron chelators on the transferrin receptor in K562 cells.

PubMed:Evidence for a role of hydroxyl radical in immune-complex-induced vasculitis.

PubMed:Inhibition of mastitic bacteria by bovine milk apo-lactoferrin evaluated by in vitro microassay of bacterial growth.

PubMed:Kinetic effect of human lactoferrin on the growth of Escherichia coli 0111.

PubMed:Supplementation of milk with iron bound to lactoferrin using weanling mice: L. Effects on hematology and tissue iron.

PubMed:The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum. Unusual resistance of human apolactoferrin to proteolytic digestion.

PubMed:Evidence for role of hydroxyl radical in complement and neutrophil-dependent tissue injury.

PubMed:Suppression of mouse myelopoiesis by administration of human lactoferrin in vivo and the comparative action of human transferrin.

PubMed:Spectroscopic studies on copper (II) complexes of human lactoferrin.

PubMed:Transferrin receptors of human fibroblasts. Analysis of receptor properties and regulation.

PubMed:Bactericidal activity of human lactoferrin: differentiation from the stasis of iron deprivation.

PubMed:Studies on human lactoferrin by electron paramagnetic resonance, fluorescence, and resonance Raman spectroscopy.

PubMed:Lactoferrin turnover in man.

PubMed:A bactericidal effect for human lactoferrin.

PubMed:In vitro growth inhibition of mastitis-causing coliform bacteria by bovine apo-lactoferrin and reversal of inhibition by citrate and high concentrations of apo-lactoferin.

PubMed:The effect of trypsin on bovine transferrin and lactoferrin.

PubMed:The involvement of lactoferrin in the hyposideremia of acute inflammation.

PubMed:Association of lactoferrin with other proteins, as demonstrated by changes in electrophoretic mobility.

apo-lactoferrin
iron-depleted form of Lactoferrin

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apo-lactoferrin iron-depleted form of Lactoferrin

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apo-lactoferrin
iron-depleted form of Lactoferrin