| Name: | piper methysticum root |
| CAS Number: | 84696-40-2 |
|
| ECHA EC Number: | 283-648-9 |
| FDA UNII: | Search |
Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | cosmetic agents |
| Recommendation for piper methysticum root usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for piper methysticum root flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
References:
| | piper methysticum root |
| Pubchem (sid): | 135283770 |
Other Information:
| FDA Listing of Food Additive Status: | View |
| Wikipedia: | View |
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| actiphyte of | kava kava root | | | kava root | | | kava-kava root | | | root of the kawa-kawa, piper methysticum, piperaceae |
Articles:
| PubMed:Flavokawains B and C, melanogenesis inhibitors, isolated from the root of Piper methysticum and synthesis of analogs. |
| PubMed:Kavain analogues as potential analgesic agents. |
| PubMed:Pacific island 'Awa (Kava) extracts, but not isolated kavalactones, promote proinflammatory responses in model mast cells. |
| PubMed:Kava: a comprehensive review of efficacy, safety, and psychopharmacology. |
| PubMed:Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways. |
| PubMed:Final report on the safety assessment of Piper methysticum leaf/root/stem extract and Piper methysticum root extract. |
| PubMed:Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. |
| PubMed:Is the alkaloid pipermethystine connected with the claimed liver toxicity of Kava products? |
| PubMed:Kava consumption and its health effects. |
| PubMed:Evaluation of commercial kava extracts and kavalactone standards for mutagenicity and toxicity using the mammalian cell gene mutation assay in L5178Y mouse lymphoma cells. |
| PubMed:In vitro cytotoxicity of nonpolar constituents from different parts of kava plant (Piper methysticum). |
| PubMed:Extracts and kavalactones of Piper methysticum G. Forst (kava-kava) inhibit P-glycoprotein in vitro. |
| PubMed:Determination of six kavalactones in dietary supplements and selected functional foods containing Piper methysticum by isocratic liquid chromatography with internal standard. |
| PubMed:Analysis of plant extracts by NIRS: simultaneous determination of kavapyrones and water in dry extracts of Piper methysticum Forst. |
| PubMed:Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. |
| PubMed:Effects of kava (Kava-kava, 'Awa, Yaqona, Piper methysticum) on c-DNA-expressed cytochrome P450 enzymes and human cryopreserved hepatocytes. |
| PubMed:Kava does not display metabolic toxicity in a homogeneous cellular assay. |
| PubMed:Extracts of kava (Piper methysticum) induce acute anxiolytic-like behavioral changes in mice. |
| PubMed:Hepatitis induced by Kava (Piper methysticum rhizoma). |
| PubMed:Acute hepatitis induced by kava kava. |
| PubMed:Kavain attenuates vascular contractility through inhibition of calcium channels. |
| PubMed:Densitometric analysis of kawain in kava-kava root extracts. |
| PubMed:Kavalactones from Piper methysticum, and their 13C NMR spectroscopic analyses. |
| PubMed:Kava pyrones exert effects on neuronal transmission and transmembraneous cation currents similar to established mood stabilizers--a review. |
| PubMed:Interaction of various Piper methysticum cultivars with CNS receptors in vitro. |
| PubMed:Inhibition of haloperidol-induced catalepsy in rats by root extracts from Piper methysticum F. |
| PubMed:[Treatment with Kava--the root to ocombat stress]. |
| PubMed:Effects of (+/-)-kavain on voltage-activated inward currents of dorsal root ganglion cells from neonatal rats. |
| PubMed:Kava dermopathy. |
| PubMed:Identification by methane chemical ionization gas chromatography/mass spectrometry of the products obtained by steam distillation and aqueous acid extraction of commercial Piper methysticum. |
|