Category:cosmetic ingredient for skin protecting
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Food Chemicals Codex Listed: | No |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | cosmetic ingredient for skin protecting |
Recommendation for trichosanthes kirilowii root extract usage levels up to: | | not for fragrance use.
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Recommendation for trichosanthes kirilowii root extract flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| extract of the roots of the chinese gourd, trichosanthes kirilowii, cucurbitaceae | | trichosanthes obtusiloba root extract |
Articles:
PubMed:Ribosome-inactivating Proteins from Root Tubers and Seeds of Trichosan-thes kirilowii and Other Trichosanthes Species. |
PubMed:In vitro Screening and Evaluation of 37 Traditional Chinese Medicines for Their Potential to Activate Peroxisome Proliferator-Activated Receptors-γ. |
PubMed:Trichosanthin-induced autophagy in gastric cancer cell MKN-45 is dependent on reactive oxygen species (ROS) and NF-κB/p53 pathway. |
PubMed:The anti-cancerous activity of recombinant trichosanthin on prostate cancer cell PC3. |
PubMed:Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway. |
PubMed:A lower pH value benefits regeneration of Trichosanthes kirilowii by somatic embryogenesis, involving rhizoid tubers (RTBs), a novel structure. |
PubMed:BDP-30, a systemic resistance inducer from Boerhaavia diffusa L., suppresses TMV infection, and displays homology with ribosome-inactivating proteins. |
PubMed:[Effect of yanghe huayan decoction on precancerosis of breast cancer, protein and mRNA expression of ki67: an experimental research]. |
PubMed:A novel extraction of trichosanthin from Trichosanthes kirilowii roots using three-phase partitioning and its in vitro anticancer activity. |
PubMed:Isolation and characterization of a rhizobacterial antagonist of root-knot nematodes. |
PubMed:Trichosanthin, a Chinese medicine for the medical treatment of ectopic pregnancy with high levels of β-hCG. |
PubMed:Identification of novel pregnane X receptor activators from traditional Chinese medicines. |
PubMed:Possible mechanisms of trichosanthin-induced apoptosis of tumor cells. |
PubMed:Trichosanthin, an extract of Trichosanthes kirilowii, effectively prevents acute rejection of major histocompatibility complex-mismatched mouse skin allograft. |
PubMed:[Tissue culture and rapid propagation of Trichosanthes kirilowii]. |
PubMed:Trichosanthin induced Th2 polarization status. |
PubMed:[Protective effects of trichosanthin in Herpes simplex virus-1 encephalitis in mice]. |
PubMed:Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties. |
PubMed:Effect of N- and C-terminal deletions on the RNA N-glycosidase activity and the antigenicity of karasurin-A, a ribosome-inactivating protein from Trichosanthes kirilowii var. japonica. |
PubMed:[Activation of G protein on the membrane of TCS-sensitive cells]. |
PubMed:[Genetic transformation of hairy roots in Trichosanthes kirilowii Maxim. by Ti and Ri plasmids]. |
PubMed:Cucurbitacins from Trichosanthes kirilowii as the inhibitory components on tyrosinase activity and melanin synthesis of B16/F10 melanoma cells. |
PubMed:Expression of recombinant trichosanthin, a ribosome-inactivating protein, in transgenic tobacco. |
PubMed:The interaction of trichosanthin with supported phospholipid membranes studied by surface plasmon resonance. |
PubMed:Anti-HIV-1 activity of trichobitacin, a novel ribosome-inactivating protein. |
PubMed:Carbohydrate specificity of an agglutinin isolated from the root of Trichosanthes kirilowii. |
PubMed:Effect of karasurin-A on nitric oxide production by murine macrophages and mitogenic response of murine splenocytes in vitro. |
PubMed:Amino acid sequences and ribosome-inactivating activities of karasurin-B and karasurin-C. |
PubMed:A new method for the detection and quantitative measurement of the contents of trichosanthes root component composing Chinese traditional medicines. |
PubMed:A simplified procedure for the purification of trichosanthin (a type 1 ribosome inactivating protein) from Trichosanthes kirilowii root tubers. |
PubMed:Cytotoxic activity of bryonolic acid isolated from transformed hairy roots of Trichosanthes kirilowii var. japonica. |
PubMed:In vitro immunotoxicity and cytotoxicity of trichosanthin against human normal immunocytes and leukemia-lymphoma cells. |
PubMed:Biosynthesis of defense-related proteins in transformed root cultures of Trichosanthes kirilowii Maxim. var japonicum (Kitam.). |
PubMed:Development and application of an enzyme immunoassay for karasurin A, an effective protein component of Trichosanthes kirilowii Max. var. japonicum Kitam. |
PubMed:Minireview: trichosanthin--a protein with multiple pharmacological properties. |
PubMed:The mechanism of action of trichosanthin on eukaryotic ribosomes--RNA N-glycosidase activity of the cytotoxin. |
PubMed:Presence of protein polymorphism in karasurin, an abortifacient and anti-tumor protein, identified with physicochemical properties. |
PubMed:Toxicity and activity of purified trichosanthin. |
PubMed:Trichosanthin-monoclonal antibody conjugate specifically cytotoxic to human hepatoma cells in vitro. |
PubMed:The complete amino acid sequence of an abortifacient protein, karasurin. |
PubMed:Isolation and characterization of a new abortifacient protein, karasurin, from root tubers of Trichosanthes kirilowii Max. var. japonicum Kitam. |
PubMed:Cloning of trichosanthin cDNA and its expression in Escherichia coli. |
PubMed:[Studies on the constituents of "Trichosanthes root". IV. Constituents of roots of Trichosanthes multiloba Miq., Trichosanthes miyagii Hay. and Chinese crude drug "karo-kon"]. |
PubMed:[Studies on the constituents of trichosanthes root. I. Constituents of roots of Trichosanthes kirilowii Maxim. var. japonicum Kitam]. |
PubMed:Beta-trichosanthin: a new abortifacient protein from the Chinese drug, wangua, Trichosanthes cucumeroides. |
PubMed:Isolation and characterization of an immunosuppressive protein from Trichosanthes kirilowii root tubers. |
PubMed:The immunomodulatory and antitumor activities of trichosanthin-an abortifacient protein isolated from tian-hua-fen (Trichosanthes kirilowii). |
PubMed:Chemical and biological characterization of the galactose binding lectins from Trichosanthes kirilowii root tubers. |
PubMed:Selective killing of choriocarcinoma cells in vitro by trichosanthin, a plant protein purified from root tubers of the Chinese medicinal herb Trichosanthes kirilowii. |
PubMed:Screening of Trichosanthes kirilowii, Momordica charantia and Cucurbita maxima (family Cucurbitaceae) for compounds with antilipolytic activity. |
PubMed:Purification, characterization and sequence determination of a double-headed trypsin inhibitor peptide from Trichosanthes kirilowii (a Chinese medical herb). |
PubMed:Studies on the mechanisms of abortion induction by Trichosanthin. |
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