angelica gigas extract

Articles:

PubMed:Development of a pharmacokinetic/pharmacodynamic/disease progression model in NC/Nga mice for development of novel anti-atopic dermatitis drugs.

PubMed:Anti-inflammatory and anti-proliferative effect of herbal medicines (APR) in RAW264.7 cells.

PubMed:Decursin prevents TPA-induced invasion through suppression of PKCα/p38/NF-κB-dependent MMP-9 expression in MCF-7 human breast carcinoma cells.

PubMed:Two novel Talaromyces species isolated from medicinal crops in Korea.

PubMed:Preventative effect of an herbal preparation (HemoHIM) on development of airway inflammation in mice via modulation of Th1/2 cells differentiation.

PubMed:A New Herbal Formula, KSG-002, Suppresses Breast Cancer Growth and Metastasis by Targeting NF- κ B-Dependent TNF α Production in Macrophages.

PubMed:Decursin and Doxorubicin Are in Synergy for the Induction of Apoptosis via STAT3 and/or mTOR Pathways in Human Multiple Myeloma Cells.

PubMed:Decursin Isolated from Angelica gigas Nakai Rescues PC12 Cells from Amyloid β-Protein-Induced Neurotoxicity through Nrf2-Mediated Upregulation of Heme Oxygenase-1: Potential Roles of MAPK.

PubMed:Decursin exerts anti-cancer activity in MDA-MB-231 breast cancer cells via inhibition of the Pin1 activity and enhancement of the Pin1/p53 association.

PubMed:Single oral dose pharmacokinetics of decursin, decursinol angelate, and decursinol in rats.

PubMed:A (S)-(+)-decursin derivative, (S)-(+)-3-(3,4-dihydroxy-phenyl)-acrylic acid 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano[3,2-g]-chromen-3-yl-ester, attenuates the development of atopic dermatitis-like lesions in NC/Nga mice.

PubMed:New discrimination method combining hit quality index based spectral matching and voting.

PubMed:Decursin inhibits UVB-induced MMP expression in human dermal fibroblasts via regulation of nuclear factor-κB.

PubMed:Ultrafine Angelica gigas powder normalizes ovarian hormone levels and has antiosteoporosis properties in ovariectomized rats: particle size effect.

PubMed:Biopharmaceutical characterization of decursin and their derivatives for drug discovery.

PubMed:The memory ameliorating effects of INM-176, an ethanolic extract of Angelica gigas, against scopolamine- or Aβ(1-42)-induced cognitive dysfunction in mice.

PubMed:Protective effects of a novel synthetic α-lipoic acid-decursinol hybrid compound in experimentally induced transient cerebral ischemia.

PubMed:Physicochemical characterization and toxicity of decursin and their derivatives from Angelica gigas.

PubMed:Anti-cancer and other bioactivities of Korean Angelica gigas Nakai (AGN) and its major pyranocoumarin compounds.

PubMed:First-pass metabolism of decursin, a bioactive compound of Angelica gigas, in rats.

PubMed:Food- and gender-dependent pharmacokinetics of paeoniflorin after oral administration with Samul-tang in rats.

PubMed:Neuroprotective effects of INM-176 against lipopolysaccharide-induced neuronal injury.

PubMed:Decursin inhibits vasculogenesis in early tumor progression by suppression of endothelial progenitor cell differentiation and function.

PubMed:Chemometric classification of morphologically similar Umbelliferae medicinal herbs by DART-TOF-MS fingerprint.

PubMed:Quantitative determination of decursin, decursinol angelate, and decursinol in mouse plasma and tumor tissue using liquid-liquid extraction and HPLC.

PubMed:Decursin, an active compound isolated from Angelica gigas, inhibits fat accumulation, reduces adipocytokine secretion and improves glucose tolerance in mice fed a high-fat diet.

PubMed:The effect of herbal extract (EstroG-100) on pre-, peri- and post-menopausal women: a randomized double-blind, placebo-controlled study.

PubMed:A synthetic decursin analog with increased in vivo stability suppresses androgen receptor signaling in vitro and in vivo.

PubMed:Anti-allergic effects and mechanisms of action of the ethanolic extract of Angelica gigas in dinitrofluorobenzene-induced inflammation models.

PubMed:Metabolite profiling of Angelica gigas from different geographical origins using 1H NMR and UPLC-MS analyses.

PubMed:Pharmacokinetic characterization of decursinol derived from Angelica gigas Nakai in rats.

PubMed:Overexpression of cinnamate 4-hydroxylase gene enhances biosynthesis of decursinol angelate in Angelica gigas hairy roots.

PubMed:Immunotoxicity activity from various essential oils of Angelica genus from South Korea against Aedes aegypti L.

PubMed:Antiplasmodial and cytotoxic activity of coumarin derivatives from dried roots of Angelica gigas Nakai in vitro.

PubMed:Protective effects of decursin and decursinol angelate against amyloid β-protein-induced oxidative stress in the PC12 cell line: the role of Nrf2 and antioxidant enzymes.

PubMed:Decursin and decursinol from Angelica gigas inhibit the lung metastasis of murine colon carcinoma.

PubMed:Enhancement of pheochromocytoma nerve cell growth by consecutive fractionization of Angelica gigas Nakai extracts.

PubMed:Cloning and characterization of phenylalanine ammonia-lyase and cinnamate 4-hydroxylase and pyranocoumarin biosynthesis in Angelica gigas.

PubMed:Decursin prevents cisplatin-induced apoptosis via the enhancement of antioxidant enzymes in human renal epithelial cells.

PubMed:A modified preparation (LMK03) of the oriental medicine Jangwonhwan reduces Abeta(1-42) level in the brain of Tg-APPswe/PS1dE9 mouse model of Alzheimer disease.

PubMed:Synergistic vasorelaxant and antihypertensive effects of Ligusticum wallichii and Angelica gigas.

PubMed:Decursinol angelate blocks transmigration and inflammatory activation of cancer cells through inhibition of PI3K, ERK and NF-kappaB activation.

PubMed:Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation.

PubMed:Ethanol extract of Angelica gigas inhibits croton oil-induced inflammation by suppressing the cyclooxygenase - prostaglandin pathway.

PubMed:Biotransformation of plant secondary metabolite decursin by Mycobacterium sp. PYR1001.

PubMed:Absorption, distribution, metabolism, and excretion of decursin and decursinol angelate from Angelica gigas Nakai.

PubMed:Antiproliferative activity of Korean wild vegetables on different human tumor cell lines.

PubMed:Evaluation of the phototoxic potential of plants used in oriental medicine.

PubMed:Anti-inflammatory effects of an ethanol extract of Angelica gigas in a Carrageenan-air pouch inflammation model.

PubMed:The analgesic effect of decursinol.

PubMed:ESP-102, a combined extract of Angelica gigas, Saururus chinensis and Schizandra chinensis, protects against glutamate-induced toxicity in primary cultures of rat cortical cells.

PubMed:Decursin and decursinol inhibit VEGF-induced angiogenesis by blocking the activation of extracellular signal-regulated kinase and c-Jun N-terminal kinase.

PubMed:Decursin and decursinol angelate inhibit VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway.

PubMed:In vivo anti-cancer activity of Korean Angelica gigas and its major pyranocoumarin decursin.

PubMed:Antidiabetic activity of angelan isolated from Angelica gigas Nakai.

PubMed:In vitro inhibitory potential of decursin and decursinol angelate on the catalytic activity of cytochrome P-450 1A1/2, 2D15, and 3A12 isoforms in canine hepatic microsomes.

PubMed:Identification of proteins binding to decursinol by chemical proteomics.

PubMed:Inhibitory effects of Angelicae Gigantis Radix on osteoclast formation.

PubMed:Antioxidant activity and cytotoxicity of methanol extracts from aerial parts of Korean salad plants.

PubMed:Neuroprotective coumarins from the root of Angelica gigas: structure-activity relationships.

PubMed:Simultaneous determination of eight coumarins in Angelica gigas and in various other Angelica species by high performance liquid chromatography and comparative micro-morphology study of Angelica species.

PubMed:The simultaneous determination of coumarins in Angelica gigas root by high performance liquid chromatography-diode array detector coupled with electrospray ionization/mass spectrometry.

PubMed:Decursin and decursinol angelate selectively inhibit NADH-fumarate reductase of Ascaris suum.

PubMed:Effect of Angelica gigas extract on melanogenesis in B16 melanoma cells.

PubMed:Decursin suppresses human androgen-independent PC3 prostate cancer cell proliferation by promoting the degradation of beta-catenin.

PubMed:Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents.

PubMed:Decursinol and decursin protect primary cultured rat cortical cells from glutamate-induced neurotoxicity.

PubMed:Mechanism-based inactivation of cytochrome P450 2A6 by decursinol angelate isolated from Angelica Gigas.

PubMed:Development of gas chromatographic/mass spectrometry-pattern recognition method for the quality control of Korean Angelica.

PubMed:Optimized conditions for the extraction of secondary volatile metabolites in Angelica roots by accelerated solvent extraction.

PubMed:Nodakenin, a coumarin compound, ameliorates scopolamine-induced memory disruption in mice.

PubMed:Transport of decursin and decursinol angelate across Caco-2 and MDR-MDCK cell monolayers: in vitro models for intestinal and blood-brain barrier permeability.

PubMed:Volatile organic compounds of Angelica gigas Nakai, Korean medicinal herb.

PubMed:A novel class of pyranocoumarin anti-androgen receptor signaling compounds.

PubMed:Angelan isolated from Angelica gigas Nakai induces dendritic cell maturation through toll-like receptor 4.

PubMed:Identification of volatile components in Angelica species using supercritical-CO2 fluid extraction and solid phase microextraction coupled to gas chromatography-mass spectrometry.

PubMed:Determination of volatile flavor components in danggui cultivars by solvent free injection and hydrodistillation followed by gas chromatographic-mass spectrometric analysis.

PubMed:Pectic polysaccharide isolated from Angelica gigas Nakai inhibits melanoma cell metastasis and growth by directly preventing cell adhesion and activating host immune functions.

PubMed:Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer.

PubMed:The essential oil from Angelica gigas NAKAI suppresses nicotine sensitization.

PubMed:New anti-inflammatory formulation containing Synurus deltoides extract.

PubMed:Decursin and PDBu: two PKC activators distinctively acting in the megakaryocytic differentiation of K562 human erythroleukemia cells.

PubMed:Involvement of PKC and ROS in the cytotoxic mechanism of anti-leukemic decursin and its derivatives and their structure-activity relationship in human K562 erythroleukemia and U937 myeloleukemia cells.

PubMed:A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells.

PubMed:ESP-102, a standardized combined extract of Angelica gigas, Saururus chinensis and Schizandra chinensis, significantly improved scopolamine-induced memory impairment in mice.

PubMed:Four new neuroprotective dihydropyranocoumarins from Angelica gigas.

PubMed:Quantification of ligustilides in the roots of Angelica sinensis and related umbelliferous medicinal plants by high-performance liquid chromatography and liquid chromatography-mass spectrometry.

PubMed:Protection against beta-amyloid peptide-induced memory impairment with long-term administration of extract of Angelica gigas or decursinol in mice.

PubMed:Anti-tumor activities of decursinol angelate and decursin from Angelica gigas.

PubMed:Antinociceptive profiles of crude extract from roots of Angelica gigas NAKAI in various pain models.

PubMed:Antibacterial coumarins from Angelica gigas roots.

PubMed:Decursin from Angelica gigas mitigates amnesia induced by scopolamine in mice.

PubMed:Experimental evidences and signal transduction pathways involved in the activation of NF-kappa B/Rel by angelan in murine macrophages.

PubMed:Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships.

PubMed:Activation of mitogen-activated protein kinase pathways by angelan in murine macrophages.

PubMed:Differential activation of murine macrophages by angelan and LPS.

PubMed:Polyacetylenes from angelica gigas and their inhibitory activity on nitric oxide synthesis in activated macrophages.

PubMed:Activation of NF-kappaB/Rel in angelan-stimulated macrophages.

PubMed:Characteristic immunostimulation by angelan isolated from Angelica gigas Nakai.

PubMed:Decursinol angelate: a cytotoxic and protein kinase C activating agent from the root of Angelica gigas.

PubMed:Decursin: a cytotoxic agent and protein kinase C activator from the root of Angelica gigas.

PubMed:Coumarins from the root of Angelica gigas Nakai.

angelica gigas extract
extract of the plant, angelica gigas, apiaceae

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angelica gigas extract extract of the plant, angelica gigas, apiaceae

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angelica gigas extract
extract of the plant, angelica gigas, apiaceae