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cynara scolymus extract (whole plant)
extract of the whole plant, cynara scolymus

Supplier Sponsors

Name:cynara scolymus extract
CAS Number: 84012-14-6
ECHA EC Number:281-659-3
FDA UNII: Search
Category:cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
 
Suppliers:
Bio-Botanica®
Artichoke, SE – 2002C
Carrubba
artichoke extract
Grau Aromatics
ARTICHOKE EXTRACT HS 2564 G
(hydrosoluble)
Indis NV
For experimental / research use only.
Artchoke Dry Extract (Cynara scolymus)
Naturex
Artichoke Extract
NAT healthy™
Noble Molecular Research
For experimental / research use only.
Artichoke Extract
OQEMA
Artichoke Extract
Phoenix Aromas & Essential Oils
Artichoke Extract
Shaanxi Y-Herb Biotechnology
Bulk Organic Artichoke Herbal Extract Powder Cynara Scolymus L. Leaf P.E. 2.5% 5%
Skyherb Technologies
Artichoke extract
Cynarin 2.5%
SRS Aromatics
ARTICHOKE EXTRACT HS 2564 G
Symrise
Actipone® Artichoke GW
Life Essentials - Botanicals
Odor: characteristic
Use: Actipone® Artichoke GW contains the juice concentrate of Cynara scolymus L. plants prepared in water and glycerin. Artichokes used for our Actipone® are mainly cultivated in Spain. The plants are harvested, cleaned and comminuted. The juice is obtained by squeezing and filtration. The filtrate is concentrated, prepared in a mixture of water, glycerin and preservatives and clear filtrated after an individual ripening time. 1kg Actipone® Artichoke GW contains the hydrophilic ingredients of approx. 800g fresh artichokes. Fresh plant material – Actipone® Artichoke GW – ratio: 0.8 : 1 Actipone® Artichoke GW shows anti-oxidant properties (in vitro).
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 1000 mg/kg
Indian Journal of Experimental Biology. Vol. 9, Pg. 91, 1971.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic agents
Recommendation for cynara scolymus extract (whole plant) usage levels up to:
 not for fragrance use.
 
Recommendation for cynara scolymus extract (whole plant) flavor usage levels up to:
 not for flavor use.
 
Safety References:
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
cynara scolymus extract
Chemidplus:0084012146
 
References:
 cynara scolymus extract
Pubchem (sid):135312255
 
Other Information:
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 cynara scolymus
Search Trop Picture
 
Synonyms:
 artichoke extract (whole plant)
 artichoke extract HS 2564 G (Grau)
actipone artichoke GW (Symrise)
 extract of the whole plant, cynara scolymus
 

Articles:

PubMed:Use of artichoke (Cynara scolymus) flower extract as a substitute for bovine rennet in the manufacture of Gouda-type cheese: characterization of aspartic proteases.
PubMed:Artichoke, cynarin and cyanidin downregulate the expression of inducible nitric oxide synthase in human coronary smooth muscle cells.
PubMed:Investigation of the in vivo antioxidative activity of Cynara scolymus (artichoke) leaf extract in the streptozotocin-induced diabetic rat.
PubMed:Lanthanide-IMAC enrichment of carbohydrates and polyols.
PubMed:Cynara Scolymus Leaf Extract Stimulates Adipogenesis in 3T3-L1 Preadipocytes and Suppresses Hepatic Glucose Output in H4IIE Hepatocytes.
PubMed:Extensive characterisation of bioactive phenolic constituents from globe artichoke (Cynara scolymus L.) by HPLC-DAD-ESI-QTOF-MS.
PubMed:Protective activity of Cynara scolymus L. leaf extract against chemically induced complex genomic alterations in CHO cells.
PubMed:Protective effect of artichoke (Cynara scolymus) leaf extract against lead toxicity in rat.
PubMed:Chemical constituents and anti-ulcerogenic potential of the scales of Cynara scolymus (artichoke) heads.
PubMed:Artichoke leaf extract for treating hypercholesterolaemia.
PubMed:Metabolic management in overweight subjects with naive impaired fasting glycaemia by means of a highly standardized extract from Cynara scolymus: a double-blind, placebo-controlled, randomized clinical trial.
PubMed:[Artichoke--untapped potential of herbal medicine in the treatment of atherosclerosis and liver diseases].
PubMed:[Development and validation of method for the determination of cynarin, luteolin in plasma].
PubMed:In vivo genotoxicity evaluation of an artichoke (Cynara scolymus L.) aqueous extract.
PubMed:Artichoke induces genetic toxicity in the cytokinesis-block micronucleus (CBMN) cytome assay.
PubMed:Separation and identification of phenolic compounds in canned artichoke by LC/DAD/ESI-MS using core-shell C18 column: a comparative study.
PubMed:Cynaropicrin from Cynara scolymus L. suppresses photoaging of skin by inhibiting the transcription activity of nuclear factor-kappa B.
PubMed:Effect of zeolite nano-materials and artichoke (Cynara scolymus L.) leaf extract on increase in urinary clearance of systematically absorbed nicotine.
PubMed:Development of an automated method for Folin-Ciocalteu total phenolic assay in artichoke extracts.
PubMed:Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on operant self-administration of a chocolate-flavoured beverage in rats.
PubMed:Artichoke induces genetic toxicity and decreases ethyl methanesulfonate-related DNA damage in Chinese hamster ovary cells.
PubMed:Beneficial effects of artichoke leaf extract supplementation on increasing HDL-cholesterol in subjects with primary mild hypercholesterolaemia: a double-blind, randomized, placebo-controlled trial.
PubMed:Reducing effect of a combination of Phaseolus vulgaris and Cynara scolymus extracts on food intake and glycemia in rats.
PubMed:Extracts of edible and medicinal plants in inhibition of growth, adherence, and cytotoxin production of Campylobacter jejuni and Campylobacter coli.
PubMed:Artichoke extract lowered plasma cholesterol and increased fecal bile acids in Golden Syrian hamsters.
PubMed:Appetite Control and Glycaemia Reduction in Overweight Subjects treated with a Combination of Two Highly Standardized Extracts from Phaseolus vulgaris and Cynara scolymus.
PubMed:Evidence of glycemia-lowering effect by a Cynara scolymus L. extract in normal and obese rats.
PubMed:Antiproliferative, protective and antioxidant effects of artichoke, dandelion, turmeric and rosemary extracts and their formulation.
PubMed:Prunella vulgaris L. Upregulates eNOS expression in human endothelial cells.
PubMed:[Phytotherapy with a mixture of dry extracts with hepato-protective effects containing artichoke leaves in the management of functional dyspepsia symptoms].
PubMed:Inhibitory effect of the flowers of artichoke (Cynara cardunculus) on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis in mouse skin.
PubMed:Effects of artichoke leaf extract on acute gastric mucosal injury in rats.
PubMed:The effect of artichoke (Cynara scolymus L.) extract on respiratory chain system activity in rat liver mitochondria.
PubMed:Artichoke leaf extract for treating hypercholesterolaemia.
PubMed:Artichoke leaf extract reduces oxidative stress and lipoprotein dyshomeostasis in rats fed on high cholesterol diet.
PubMed:Effect of artichoke leaf extract on hepatic and cardiac oxidative stress in rats fed on high cholesterol diet.
PubMed:Artichoke leave extract for chronic hepatitis C - a pilot study.
PubMed:The effect of artichoke (Cynara scolymus L.) extract on ROS generation in HUVEC cells.
PubMed:Effect of pretreatment with artichoke extract on carbon tetrachloride-induced liver injury and oxidative stress.
PubMed:The influence of supplementation with artichoke (Cynara scolymus L.) extract on selected redox parameters in rowers.
PubMed:Effect of two artichoke extracts (36_U and 36_EB) on rat ileum (with respect to bowel syndrome) and the peristaltic threshold.
PubMed:Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled trial.
PubMed:Effect of artichoke extract (Cynara scolymus L.) on palmitic-1-14C acid oxidation in rats.
PubMed:Flavonoids of Cynara scolymus possess potent xanthinoxidase inhibitory activity in vitro but are devoid of hypouricemic effects in rats after oral application.
PubMed:Effects of artichoke extract supplementation on gonads of cadmium-treated rats.
PubMed:Clinical uses of artichoke leaf extract.
PubMed:Research on biomodulatory effect of natural compounds.
PubMed:Tabletted microspheres containing Cynara scolymus (var. Spinoso sardo) extract for the preparation of controlled release nutraceutical matrices.
PubMed:Time-resolved spectral studies of blue-green fluorescence of artichoke (Cynara cardunculus L. Var. Scolymus) leaves: identification of chlorogenic acid as one of the major fluorophores and age-mediated changes.
PubMed:Choleretic effects of yarrow (Achillea millefolium s.l.) in the isolated perfused rat liver.
PubMed:Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans.
PubMed:Antifungal activity of Cynara scolymus L. extracts.
PubMed:Purification of cynarases from artichoke (Cynara scolymus L.): enzymatic properties of cynarase A.
PubMed:Purification and characterization of a milk-clotting aspartic proteinase from globe artichoke (Cynara scolymus L.).
PubMed:Experimental mycotoxicosis in chickens induced by ochratoxin A and penicillic acid and intervention with natural plant extracts.
PubMed:Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities.
PubMed:Artichoke leaf extract reduces symptoms of irritable bowel syndrome and improves quality of life in otherwise healthy volunteers suffering from concomitant dyspepsia: a subset analysis.
PubMed:Flavonoids from artichoke (Cynara scolymus L.) up-regulate endothelial-type nitric-oxide synthase gene expression in human endothelial cells.
PubMed:Effectiveness of artichoke extract in preventing alcohol-induced hangovers: a randomized controlled trial.
PubMed:Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia: a six-week placebo-controlled, double-blind, multicentre trial.
PubMed:Validated method for the determination of six metabolites derived from artichoke leaf extract in human plasma by high-performance liquid chromatography-coulometric-array detection.
PubMed:Screening pharmaceutical preparations containing extracts of turmeric rhizome, artichoke leaf, devil's claw root and garlic or salmon oil for antioxidant capacity.
PubMed:Occupational rhinitis and bronchial asthma due to artichoke (Cynara scolymus).
PubMed:Efficacy of different Cynara scolymus preparations on liver complaints.
PubMed:Choleretic activity and biliary elimination of lipids and bile acids induced by an artichoke leaf extract in rats.
PubMed:Anti-hyperlipidemic sesquiterpenes and new sesquiterpene glycosides from the leaves of artichoke (Cynara scolymus L.): structure requirement and mode of action.
PubMed:Protective properties of artichoke (Cynara scolymus) against oxidative stress induced in cultured endothelial cells and monocytes.
PubMed:Artichoke (Cynara scolymus L.) byproducts as a potential source of health-promoting antioxidant phenolics.
PubMed:Electrospray characterization of selected medicinal plant extracts.
PubMed:Artichoke leaf extract - Recent findings reflecting effects on lipid metabolism, liver and gastrointestinal tracts.
PubMed:[Action of an extract of artichoke (Cynara scolymus) on cholesterolesterase in vitro].
 
Notes:
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