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Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | cosmetic agents |
| Recommendation for polypodium leucotomos leaf extract usage levels up to: | | | not for fragrance use.
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| Recommendation for polypodium leucotomos leaf extract flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | extract of the leaves of polypodium leucotomos, polypodiaceae | | calaguala | fern leaf extract | | cabbage palm | fern leaf extract | | gold-foot | fern leaf extract | | golden serpent | fern leaf extract |
Articles:
| PubMed:Current knowledge in Polypodium leucotomos effect on skin protection. |
| PubMed:Sun protection in a pill: the photoprotective properties of Polypodium leucotomos extract. |
| PubMed:Oral administration of Polypodium leucotomos delays skin tumor development and increases epidermal p53 expression and the anti-oxidant status of UV-irradiated hairless mice. |
| PubMed:Polypodium leucotomos as an Adjunct Treatment of Pigmentary Disorders. |
| PubMed:Role of oral Polypodium leucotomos extract in dermatologic diseases: a review of the literature. |
| PubMed:Photoprotection: part I. Photoprotection by naturally occurring, physical, and systemic agents. |
| PubMed:A randomized, double-blinded, placebo-controlled trial of oral Polypodium leucotomos extract as an adjunct to sunscreen in the treatment of melasma. |
| PubMed:Polypodium leucotomos Extract use to prevent and reduce the risk of infectious diseases in high performance athletes. |
| PubMed:Benefits of oral Polypodium Leucotomos extract in MM high-risk patients. |
| PubMed:Polypodium leucotomos decreases UV-induced epidermal cell proliferation and enhances p53 expression and plasma antioxidant capacity in hairless mice. |
| PubMed:New horizons in treating disorders of hyperpigmentation in skin of color. |
| PubMed:Subacute cutaneous lupus erythematosus: a case report of Polypodium leucotomos as an adjuvant therapy. |
| PubMed:Polypodium leucotomos extract in atopic dermatitis: a randomized, double-blind, placebo-controlled, multicenter trial. |
| PubMed:Fernblock, a nutriceutical with photoprotective properties and potential preventive agent for skin photoaging and photoinduced skin cancers. |
| PubMed:Oral administration of a hydrophilic extract of Polypodium leucotomos for the prevention of polymorphic light eruption. |
| PubMed:Oral polypodium leucotomos extract photoprotective activity in 57 patients with idiopathic photodermatoses. |
| PubMed:Which plant for which skin disease? Part 2: Dermatophytes, chronic venous insufficiency, photoprotection, actinic keratoses, vitiligo, hair loss, cosmetic indications. |
| PubMed:Mechanistic insights in the use of a Polypodium leucotomos extract as an oral and topical photoprotective agent. |
| PubMed:Decrease of ultraviolet A light-induced "common deletion" in healthy volunteers after oral Polypodium leucotomos extract supplement in a randomized clinical trial. |
| PubMed:Interventions for vitiligo. |
| PubMed:Polypodium leucotomos extract decreases UV-induced Cox-2 expression and inflammation, enhances DNA repair, and decreases mutagenesis in hairless mice. |
| PubMed:Cancer cell growth and extracellular matrix remodeling mechanism of ascorbate; beneficial modulation by P. leucotomos. |
| PubMed:Beneficial regulation of matrixmetalloproteinases and their inhibitors, fibrillar collagens and transforming growth factor-beta by Polypodium leucotomos, directly or in dermal fibroblasts, ultraviolet radiated fibroblasts, and melanoma cells. |
| PubMed:Current and emerging therapy for the management of vitiligo. |
| PubMed:Natural antioxidants. |
| PubMed:Polypodium leucotomos inhibits ultraviolet B radiation-induced immunosuppression. |
| PubMed:A review of DNA repair and possible DNA-repair adjuvants and selected natural anti-oxidants. |
| PubMed:Polypodium leucotomos extract inhibits glutathione oxidation and prevents Langerhans cell depletion induced by UVB/UVA radiation in a hairless rat model. |
| PubMed:Less-known botanical cosmeceuticals. |
| PubMed:Pharmacological immunomodulation of surgical trauma. |
| PubMed:A Polypodium leucotomos extract inhibits solar-simulated radiation-induced TNF-alpha and iNOS expression, transcriptional activation and apoptosis. |
| PubMed:Polypodium leucotomos extract: a nutraceutical with photoprotective properties. |
| PubMed:Treatment of vitiligo vulgaris with narrow-band UVB and oral Polypodium leucotomos extract: a randomized double-blind placebo-controlled study. |
| PubMed:Immunomodulation of the response to excretory/secretory antigens of Fasciola hepatica by Anapsos in Balb/C mice and rat alveolar macrophages. |
| PubMed:Progress in the development of Fasciola hepatica vaccine using recombinant fatty acid binding protein with the adjuvant adaptation system ADAD. |
| PubMed:Photoprotective activity of oral polypodium leucotomos extract in 25 patients with idiopathic photodermatoses. |
| PubMed:Phenolic components and antioxidant activity of Fernblock, an aqueous extract of the aerial parts of the fern Polypodium leucotomos. |
| PubMed:Systemic immunomodulatory effects of Polypodium leucotomos as an adjuvant to PUVA therapy in generalized vitiligo: A pilot study. |
| PubMed:Polypodium leucotomos extract inhibits trans-urocanic acid photoisomerization and photodecomposition. |
| PubMed:Polypodium leucotomos extract: antioxidant activity and disposition. |
| PubMed:Oral Polypodium leucotomos extract decreases ultraviolet-induced damage of human skin. |
| PubMed:Vaccination of mice and sheep with Fh12 FABP from Fasciola hepatica using the new adjuvant/immunomodulator system ADAD. |
| PubMed:Orally administered Polypodium leucotomos extract decreases psoralen-UVA-induced phototoxicity, pigmentation, and damage of human skin. |
| PubMed:Predominant effects of Polypodium leucotomos on membrane integrity, lipid peroxidation, and expression of elastin and matrixmetalloproteinase-1 in ultraviolet radiation exposed fibroblasts, and keratinocytes. |
| PubMed:Photoprotective properties of a hydrophilic extract of the fern Polypodium leucotomos on human skin cells. |
| PubMed:Modulation by Polypodium leucotomos extract of cytokine patterns in experimental trichomoniasis model. |
| PubMed:Anapsos (Polypodium leucotomos) modulates lymphoid cells and the expression of adhesion molecules. |
| PubMed:The antioxidant action of Polypodium leucotomos extract and kojic acid: reactions with reactive oxygen species. |
| PubMed:An extract of the fern Polypodium leucotomos (Difur) modulates Th1/Th2 cytokines balance in vitro and appears to exhibit anti-angiogenic activities in vivo: pathogenic relationships and therapeutic implications. |
| PubMed:Modulation by Anapsos (Polypodium leucotomos extract) of the antibody responses against the nematode parasite Trichinella spiralis. |
| PubMed:An extract of Polypodium leucotomos appears to minimize certain photoaging changes in a hairless albino mouse animal model. A pilot study. |
| PubMed:Effects of anapsos on the activity of the enzyme Cu-Zn-superoxide dismutase in an animal model of neuronal degeneration. |
| PubMed:Topical or oral administration with an extract of Polypodium leucotomos prevents acute sunburn and psoralen-induced phototoxic reactions as well as depletion of Langerhans cells in human skin. |
| PubMed:An extract of the fern Polypodium leucotomos inhibits human peripheral blood mononuclear cells proliferation in vitro. |
| PubMed:Effect of Anapsos (Polypodium leucotomos extract) on in vitro production of cytokines. |
| PubMed:Inhibition of ultraviolet-induced formation of reactive oxygen species, lipid peroxidation, erythema and skin photosensitization by polypodium leucotomos. |
| PubMed:In vitro studies on the immunomodulating effects of polypodium leucotomos extract on human leukocyte fractions. |
| PubMed:Vitiligo repigmentation with Anapsos (Polypodium leucotomos) |
| PubMed:[2 years personal experience in anapsos treatment of psoriasis in various clinical forms]. |
| PubMed:A new agent (hydrophilic fraction of polypodium leucotomos) for management of psoriasis. |
| PubMed:Metabolic effects of calagualine, an antitumoral saponine of Polypodium leucotomos. |
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