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Category:cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | cosmetic ingredient for skin conditioning |
| IFRA Critical Effect: | | Dermal sensitization |
| | View the IFRA Standard |
| Recommendation for saussurea lappa root extract usage levels up to: | | | PROHIBITED: Should not be used as a fragrance ingredient.
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| Recommendation for saussurea lappa root extract flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | saussurea lappa extract |
| Pubchem (sid): | 135309294 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | aucklandia costus root extract | | | costus root extract | | | extract of the roots of the costus, saussurea lappa, asteraceae | | | saussurea costus root extract |
Articles:
| PubMed:UPLC/MS/MS method for quantification and cytotoxic activity of sesquiterpene lactones isolated from Saussurea lappa. |
| PubMed:Volatile constituents of Saussurea costus roots cultivated in Uttarakhand Himalayas, India. |
| PubMed:Evaluation of anti-resistant activity of Auklandia (Saussurea lappa) root against some human pathogens. |
| PubMed:Aqueous extract of Saussurea lappa root ameliorate oxidative myocardial injury induced by isoproterenol in rats. |
| PubMed:Santamarin, a sesquiterpene lactone isolated from Saussurea lappa, represses LPS-induced inflammatory responses via expression of heme oxygenase-1 in murine macrophage cells. |
| PubMed:Larvicidal activity of medicinal plant extracts and lignan identified in Phryma leptostachya var. asiatica roots against housefly (Musca domestica L.). |
| PubMed:Matrix solid-phase dispersion extraction coupled with HPLC-diode array detection method for the analysis of sesquiterpene lactones in root of Saussurea lappa C.B.Clarke. |
| PubMed:Dehydrocostus lactone prevents mitochondrial dysfunction in osteoblastic MC3T3-E1 cells. |
| PubMed:A new sesquiterpene and other constituents from Saussurea lappa root. |
| PubMed:Antihepatotoxic activity of Saussurea lappa extract on D-galactosamine and lipopolysaccharide-induced hepatitis in mice. |
| PubMed:Apoptosis of DU145 human prostate cancer cells induced by dehydrocostus lactone isolated from the root of Saussurea lappa. |
| PubMed:Authentication of Saussurea lappa, an endangered medicinal material, by ITS DNA and 5S rRNA sequencing. |
| PubMed:Effects of Saussurea lappa roots extract in ethanol on leukocyte phagocytic activity, lymphocyte proliferation and interferon-gamma (IFN-gamma). |
| PubMed:Presence of cholinergic and calcium antagonist constituents in Saussurea lappa explains its use in constipation and spasm. |
| PubMed:Saussurea lappa induces G2-growth arrest and apoptosis in AGS gastric cancer cells. |
| PubMed:Costunolide inhibits interleukin-1beta expression by down-regulation of AP-1 and MAPK activity in LPS-stimulated RAW 264.7 cells. |
| PubMed:Cytotoxic sesquiterpene lactones from the root of Saussurea lappa. |
| PubMed:Germacrenes from fresh costus roots. |
| PubMed:Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release. |
| PubMed:Inhibition of inducible nitric oxide synthesis by the herbal preparation Padma 28 in macrophage cell line. |
| PubMed:Effect of dehydrocostus lactone and costunolide from Saussurea root on the central nervous system in mice. |
| PubMed:Effect of polyols on heat inactivation of Aspergillus niger van Teighem inulinase. |
| PubMed:Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells. |
| PubMed:Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix. |
| PubMed:Sesquiterpenoids from costum root oil (Saussurea lappa Clarke) |
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