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aristolochia clematitis extract
birthwort extract

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Name:	aristolochia clematitis l. extract
CAS Number:	84775-44-0
ECHA EC Number:	283-873-2
FDA UNII:	Search

Category:information only not used for fragrances or flavors

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

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Physical Properties:

Food Chemicals Codex Listed:

No

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

None found

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
information only not used for fragrances or flavors
Recommendation for aristolochia clematitis extract usage levels up to:
	not for fragrance use.

Recommendation for aristolochia clematitis extract flavor usage levels up to:
	not for flavor use.

Safety References:

Daily Med:search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

aristolochia clematitis l. extract

Chemidplus:0084775440

References:

	aristolochia clematitis l. extract
Pubchem (sid):	135285946

Other Information:

Wikipedia:

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

aristolochia clematitis
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Synonyms:

	aristolochia extract
	aristolochia tenuis extract
	birthwort extract
	serpentaria extract

Articles:

PubMed:Aristolochia clematitis, the herb responsible for aristolochic acid nephropathy, in an uncultivated piece of land of an Italian nephrologist.

PubMed:Therapeutic remedies based on Aristolochia clematitis in the main foci of Balkan endemic nephropathy in Romania.

PubMed:[Experiments on the mechanism of action of Aristolochia clematitis L].

PubMed:[Contributions to a supplement to the homeopathic pharmacopeia. VII. Aristolochia clematitis].

PubMed:[Phytotherapy of trichomonal vaginitis with Aristolochia clematitis].

PubMed:[Aristolochia clematitis as a remedy in purulent infections, wounds, and phlebitis].

PubMed:[Aristolochia clematitis (European birthwort)].

PubMed:Renal cell carcinomas of chronic kidney disease patients harbor the mutational signature of carcinogenic aristolochic acid.

PubMed:Ethnoveterinary practices of Covasna County, Transylvania, Romania.

PubMed:Chronic dietary exposure to aristolochic acid and kidney function in native farmers from a Croatian endemic area and Bosnian immigrants.

PubMed:Exceptionally long-term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy.

PubMed:Analysis of TP53 mutation spectra reveals the fingerprint of the potent environmental carcinogen, aristolochic acid.

PubMed:Evaluation of the cytotoxicity and genotoxicity of aristolochic acid I - a component of Aristolochiaceae plant extracts used in homeopathy.

PubMed:Endemic nephropathy: the case for chronic poisoning by aristolochia.

PubMed:Local uses of Aristolochia species and content of nephrotoxic aristolochic acid 1 and 2--a global assessment based on bibliographic sources.

PubMed:Aristolochic acid nephropathy: a worldwide problem.

PubMed:Role of environmental toxins in endemic (Balkan) nephropathy. October 2006, Zagreb, Croatia.

PubMed:Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.

PubMed:Induction of structural chromosome aberrations and sister chromatid exchanges in human lymphocytes in vitro by aristolochic acid.

Notes:

a plant genus of the family aristolochiaceae. species of this genus have been used in traditional medicine but they contain aristolochic acid which is associated with nephropathy. these are sometimes called 'snakeroot' but that name is also used with a number of other plants such as polygala; sanicula; asarum; aristolochia; ageratina; and others.

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