areca caticula extract, 94349-64-1

Articles:

PubMed:Usefulness of pumpkin seeds combined with areca nut extract in community-based treatment of human taeniasis in northwest Sichuan Province, China.

PubMed:Toxicity of areca nut ingredients: activation of CHK1/CHK2, induction of cell cycle arrest, and regulation of MMP-9 and TIMPs production in SAS epithelial cells.

PubMed:Areca nut extracts increased the expression of cyclooxygenase-2, prostaglandin E2 and interleukin-1α in human immune cells via oxidative stress.

PubMed:Anti-migraine effect of Areca Catechu L. nut extract in bradykinin-induced plasma protein extravasation and vocalization in rats.

PubMed:Protective Effect of Areca catechu Leaf Ethanol Extract Against Ethanol-Induced Gastric Ulcers in ICR Mice.

PubMed:Areca nut extract induces pyknotic necrosis in serum-starved oral cells via increasing reactive oxygen species and inhibiting GSK3β: an implication for cytopathic effects in betel quid chewers.

PubMed:Long-term stimulation of areca nut components results in increased chemoresistance through elevated autophagic activity.

PubMed:Potential antidepressant activity of Areca catechu nut via elevation of serotonin and noradrenaline in the hippocampus of rats.

PubMed:Areca nut contributes to oral malignancy through facilitating the conversion of cancer stem cells.

PubMed:The anti-inflammatory effect of Indonesian Areca catechu leaf extract in vitro and in vivo.

PubMed:Induction of chromosome instability and stomach cancer by altering the expression pattern of mitotic checkpoint genes in mice exposed to areca-nut.

PubMed:Direct-acting DNA alkylating agents present in aqueous extracts of areca nut and its products.

PubMed:Separation of polyphenols and arecoline from areca nut (Areca catechu L.) by solvent extraction, its antioxidant activity, and identification of polyphenols.

PubMed:Inhibition of Tanshinone IIA, salvianolic acid A and salvianolic acid B on Areca nut extract-induced oral submucous fibrosis in vitro.

PubMed:The Protective Effects of Areca catechu Extract on Cognition and Social Interaction Deficits in a Cuprizone-Induced Demyelination Model.

PubMed:Areca nut-induced buccal mucosa fibroblast contraction and its signaling: a potential role in oral submucous fibrosis--a precancer condition.

PubMed:Epithelial atrophy in oral submucous fibrosis is mediated by copper (II) and arecoline of areca nut.

PubMed:Effects of Areca Nut Extracts on Phagocytosis of Actinobacillus actinomycete mcomitans ATCC 33384 by Neutrophils in Patients with Chronic Periondontitis.

PubMed:Activation of TGF-β pathway by areca nut constituents: a possible cause of oral submucous fibrosis.

PubMed:Downregulation of Ches1 and other novel genes in oral cancer cells chronically exposed to areca nut extract.

PubMed:Areca nut procyanidins ameliorate streptozocin-induced hyperglycemia by regulating gluconeogenesis.

PubMed:Association between areca-stimulated vimentin expression and the progression of head and neck cancers.

PubMed:Areca-nut extract modulates antigen-specific immunity and augments inflammation in ovalbumin-sensitized mice.

PubMed:Antibacterial, mechanical, and barrier properties of sago starch film incorporated with Betel leaves extract.

PubMed:Precocious anaphase and expression of Securin and p53 genes as candidate biomarkers for the early detection in areca nut-induced carcinogenesis.

PubMed:Areca nut extract upregulates vimentin by activating PI3K/AKT signaling in oral carcinoma.

PubMed:Potential analgesic, anti-inflammatory and antioxidant activities of hydroalcoholic extract of Areca catechu L. nut.

PubMed:Cytotoxicity and transformation of C3H10T1/2 cells induced by areca nut components.

PubMed:[Chemical constituents from the fruits of Areca catechu].

PubMed:The inhibiting activity of areca inflorescence extracts on human low density lipoprotein oxidation induced by cupric ion.

PubMed:Effects of areca nut extract on the apoptosis pathways in human neutrophils.

PubMed:Peroxidase as the major protein constituent in areca nut and identification of its natural substrates.

PubMed:Areca nut extract induced oxidative stress and upregulated hypoxia inducing factor leading to autophagy in oral cancer cells.

PubMed:Impacts of autophagy-inducing ingredient of areca nut on tumor cells.

PubMed:Evaluation of anti-migraine potential of Areca catechu to prevent nitroglycerin-induced delayed inflammation in rat meninges: possible involvement of NOS inhibition.

PubMed:Bronchial epithelium-derived IL-8 and RANTES increased bronchial smooth muscle cell migration and proliferation by Krüppel-like factor 5 in areca nut-mediated airway remodeling.

PubMed:Areca nut components affect COX-2, cyclin B1/cdc25C and keratin expression, PGE2 production in keratinocyte is related to reactive oxygen species, CYP1A1, Src, EGFR and Ras signaling.

PubMed:Betel nut extract and arecoline block insulin signaling and lipid storage in 3T3-L1 adipocytes.

PubMed:Autophagy induction by the 30-100kDa fraction of areca nut in both normal and malignant cells through reactive oxygen species.

PubMed:Stimulatory effects of areca nut extracts on prostaglandin E2 production by human polymorphonuclear leukocytes.

PubMed:Involvement of the mitochondrion-dependent pathway and oxidative stress in the apoptosis of murine splenocytes induced by areca nut extract.

PubMed:Areca nut extract represses migration and differentiation while activating matrix metalloproteinase-9 of normal gingival epithelial cells.

PubMed:Absorption of intestinal free cholesterol is lowered by supplementation of Areca catechu L. extract in rats.

PubMed:Highly oligomeric procyanidins from areca nut induce lymphocyte apoptosis via the depletion of intracellular thiols.

PubMed:Effects of Areca catechu L. containing procyanidins on cyclooxygenase-2 expression in vitro and in vivo.

PubMed:Supplementation of Areca catechu L. extract alters triglyceride absorption and cholesterol metabolism in rats.

PubMed:Studies on anti-inflammatory and analgesic activities of betel nut in rodents.

PubMed:Lower absorption of cholesteryl oleate in rats supplemented with Areca catechu L. extract.

PubMed:Areca nut extract lowers the permeability of vaginal mucosa to reduced arecoline and arecaidine.

PubMed:A preliminary study of arecoline and guvacoline presence in the saliva of a "betel-quid" chewer using liquid-chromatography ion trap mass spectrometry.

PubMed:Editorial. Oral submucous fibrosis: revised hypotheses as to its cause.

PubMed:Areca nut extract and arecoline induced the cell cycle arrest but not apoptosis of cultured oral KB epithelial cells: association of glutathione, reactive oxygen species and mitochondrial membrane potential.

PubMed:In vitro genotoxic effects of areca nut extract and arecoline.

PubMed:Ripe areca nut extract induces G1 phase arrests and senescence-associated phenotypes in normal human oral keratinocyte.

PubMed:Areca nut extract-treated gingival fibroblasts modulate the invasiveness of polymorphonuclear leukocytes via the production of MMP-2.

PubMed:Areca nut extracts increased expression of inflammatory cytokines, tumor necrosis factor-alpha, interleukin-1beta, interleukin-6 and interleukin-8, in peripheral blood mononuclear cells.

PubMed:The effect of baked areca nut extract on the growth of buccal mucosa fibroblasts from healthy non-areca nut chewers.

PubMed:[Research on inhibition of areca nut extract on human buccal keratinocytes].

PubMed:Areca (betel) nut extract activates mitogen-activated protein kinases and NF-kappaB in oral keratinocytes.

PubMed:Establishment of OC3 oral carcinoma cell line and identification of NF-kappa B activation responses to areca nut extract.

PubMed:Areca nut extract inhibits the growth, attachment, and matrix protein synthesis of cultured human gingival fibroblasts.

PubMed:Areca nut extracts reduce the intracellular reactive oxygen species and release of myeloperoxidase by human polymorphonuclear leukocytes.

PubMed:Areca nut extract up-regulates prostaglandin production, cyclooxygenase-2 mRNA and protein expression of human oral keratinocytes.

PubMed:Fibrotic Effects of Arecoline N-Oxide in Oral Potentially Malignant Disorders.

PubMed:Clinico-immunochemical studies on airborne Areca catechu L. Pollen, a probable risk factor in emergency asthma hospitalization from Eastern India.

PubMed:Oxidative damage to DNA induced by areca nut extract.

PubMed:Areca nut extract treatment down-regulates involucrin in normal human oral keratinocyte through P13K/AKT activation.

PubMed:Modulation of KGF-1 gene expression in oral fibroblasts by ripe areca nut extract.

PubMed:Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline.

PubMed:Prevention of the areca nut extract-induced unscheduled DNA synthesis of gingival keratinocytes by vitamin C and thiol compounds.

PubMed:Mini review on chemotherapy of taeniasis and cysticercosis due to Taenia solium in Asia, and a case report with 20 tapeworms in China.

PubMed:[Study on the cytotoxic and DNA damaging effects in oral mucosal fibroblasts by areca nut extract].

PubMed:Antiovulatory and abortifacient effects of Areca catechu (betel nut) in female rats.

PubMed:In vitro cytotoxicity study of agave americana, strychnos nuxvomica and areca catechu extracts using mcf-7 cell line.

PubMed:Effect of lime composition on the formation of reactive oxygen species from areca nut extract in vitro.

PubMed:Areca nut extract treatment elicits the fibroblastoid morphological changes, actin re-organization and signaling activation in oral keratinocytes.

PubMed:Altered BRCA1 and BRCA2 responses and mutation of BRCA1 gene in mice exposed chronically and transgenerationally to aqueous extract of betel nut (AEBN).

PubMed:Induction of the c-jun protooncogene expression by areca nut extract and arecoline on oral mucosal fibroblasts.

PubMed:Areca nut extract suppresses T-cell activation and interferon-gamma production via the induction of oxidative stress.

PubMed:Arecoline and the 30-100 kDa fraction of areca nut extract differentially regulate mTOR and respectively induce apoptosis and autophagy: a pilot study.

PubMed:Up-regulation of inflammatory signalings by areca nut extract and role of cyclooxygenase-2 -1195G>a polymorphism reveal risk of oral cancer.

PubMed:Possible mechanism of betel-quid-extract-induced expression of matrix metalloproteinase-2.

PubMed:Areca nut: a review.

PubMed:Effect of betel/areca nut (Areca catechu) extracts on intestinal epithelial cell lining.

PubMed:Areca-treated fibroblasts enhance tumorigenesis of oral epithelial cells.

PubMed:Effects of areca nut on growth, differentiation and formation of DNA damage in cultured human buccal epithelial cells.

PubMed:Areca nut-induced micronuclei and cytokinesis failure in Chinese hamster ovary cells is related to reactive oxygen species production and actin filament deregulation.

PubMed:Role of areca nut in betel quid-associated chemical carcinogenesis: current awareness and future perspectives.

PubMed:Association of expression aberrances and genetic polymorphisms of lysyl oxidase with areca-associated oral tumorigenesis.

PubMed:Effects of areca nut, inflorescence piper betle extracts and arecoline on cytotoxicity, total and unscheduled DNA synthesis in cultured gingival keratinocytes.

PubMed:Contractile effect of radish and betel nut extracts on rabbit gallbladder.

PubMed:Monoamine oxidase A variants are associated with heavy betel quid use.

PubMed:Qualitative and quantitative HPLC/MS determination of proanthocyanidins in areca nut (Areca catechu).

PubMed:Association between the rs2910164 polymorphism in pre-mir-146a and oral carcinoma progression.

PubMed:Therapeutic interventions in oral submucous fibrosis: an experimental and clinical study.

PubMed:Areca-nut toxicity in cultured human buccal epithelial cells.

PubMed:Ultrastructural alterations in liver of mice exposed chronically and transgenerationally to aqueous extract of betel nut: Implications in betel nut-induced carcinogenesis.

PubMed:Treatment of experimental heterophyiasis with two plant extracts, areca nut and pumpkin seed.

PubMed:Chemical and analytical aspects of areca nut.

PubMed:Ingredients contribute to variation in production of reactive oxygen species by areca quid.

PubMed:Observations on the effect of areca nut extracts on oral fibroblast proliferation.

PubMed:Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase.

PubMed:Identification of antiplatelet and acetylcholinesterase inhibitory constituents in betel nut.

PubMed:Autophagy induction by a natural ingredient of areca nut.

PubMed:The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation.

PubMed:Molluscicidal activity of Carica papaya and Areca catechu against the freshwater snail Lymnaea acuminata.

PubMed:Dose-dependent genotoxic effect of pan masala and areca nut in the Salmonella typhimurium assay.

PubMed:Increased expression of matrix metalloproteinase-2 in oral cells after short-term stimulation and long-term usage of areca quid.

PubMed:Prognostic role of c-Jun activation in patients with areca quid chewing-related oral squamous cell carcinomas in Taiwan.

PubMed:Is the blood donated by habitual nut quid chewers suitable for use in transfusion?

PubMed:[Preparation and pharmacodynamics studies on anti-inflammatory effect of catechu gel].

PubMed:Purification of Cu/Zn superoxide dismutase from Piper betle leaf and its characterization in the oral cavity.

PubMed:Anti-depressant activities of Areca catechu fruit extract.

PubMed:Oral microflora in betel-chewing adults of the Karen tribe in Thailand.

PubMed:Chemical composition and toxicity of Taiwanese betel quid extract.

PubMed:The effects of areca catechu L extract on anti-inflammation and anti-melanogenesis.

PubMed:The effects of areca catechu L extract on anti-aging.

PubMed:Cytotoxic and genotoxic effects of areca nut-related compounds in cultured human buccal epithelial cells.

PubMed:Inhibitory effect of betel quid on the volatility of methyl mercaptan.

PubMed:Cardio-selective inhibitory effect of the betel nut extract: possible explanation.

PubMed:Antimutagenic and anticarcinogenic effects of betel leaf extract against the tobacco-specific nitrosamine 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK).

PubMed:Carcinogenicity of betel quid ingredients: feeding mice with aqueous extract and the polyphenol fraction of betel nut.

PubMed:Study of the genotoxicity of the total aqueous extract of betel nut and its tannin.

PubMed:Up-regulation of matrix metalloproteinase-8 by betel quid extract and arecoline and its role in 2D motility.

PubMed:Striatal dopamine release regulation by the cholinergic properties of the smokeless tobacco, gutkha.

PubMed:Aqueous extract of betel-nut of north-east India induces DNA-strand breaks and enhances rate of cell proliferation in vitro. Effects of betel-nut extract in vitro.

PubMed:The mutagenicity of nitrite-treated aqueous extract of Piper betle L.

PubMed:Establishment and characterization of a cell line (HCDB-1) derived from a hamster buccal pouch carcinoma induced by DMBA and Taiwanese betel quid extract.

PubMed:Dual role of betel leaf extract on thyroid function in male mice.

PubMed:Specific induction of the high-molecular-weight microtubule-associated protein 2 (hmw-MAP2) by betel quid extract in cultured oral keratinocytes: clinical implications in betel quid-associated oral squamous cell carcinoma (OSCC).

PubMed:Antimutagenic effects of betel leaf extract against the mutagenicity of two tobacco-specific N-nitrosamines.

PubMed:Genotoxic effect of raw betel-nut extract in relation to endogenous glutathione levels and its mechanism of action in mammalian cells.

PubMed:Chemopreventive efficacy of a betel leaf extract against benzo[a]pyrene-induced forestomach tumors in mice.

PubMed:Chemopreventive efficacy of betel leaf extract and its constituents on 7,12-dimethylbenz(a)anthracene induced carcinogenesis and their effect on drug detoxification system in mouse skin.

PubMed:Anticarcinogenic effect of betel leaf extract against tobacco carcinogens.

PubMed:The effect of betel nut extract on cell growth and prostaglandin endoperoxide synthase in human epidermoid carcinoma cells.

PubMed:Availability and characteristics of betel products in the U.S.

PubMed:Carcinogenic effect of a dimethyl sulphoxide extract of betel nut on the mucosa of the hamster buccal pouch.

PubMed:Screening for hemostatic activities of popular Chinese medicinal herbs in vitro.

PubMed:Thai herbal formulas used for wound treatment: a study of their antibacterial potency, anti-inflammatory, antioxidant, and cytotoxicity effects.

PubMed:Signaling pathways for induction of platelet aggregation by SAS tongue cancer cells--a mechanism of hematogenous metastasis.

PubMed:Formation of reactive oxygen species and of 8-hydroxydeoxyguanosine in DNA in vitro with betel quid ingredients.

PubMed:Presence of cholinomimetic and acetylcholinesterase inhibitory constituents in betel nut.

PubMed:Inhibitory effect of betel nut extracts on endogenous nitrosation in humans.

PubMed:Consumption of guava (Psidium guajava L) and noni (Morinda citrifolia L) may protect betel quid-chewing Papua New Guineans against diabetes.

PubMed:Promoting activity of betel quid ingredients and their inhibition by retinol.

PubMed:Development of photochemoprotective herbs containing cosmetic formulations for improving skin properties.

PubMed:Oral submucous fibrosis in a 12-year-old girl: case report.

PubMed:Protection from pan masala induced genomic damage by beta-carotene and retinoic acid--an in vitro experience.

PubMed:Formation of reactive oxygen species and of 8-hydroxy-2'-deoxyguanosine in DNA in vitro with betel-quid ingredients.

PubMed:Src family kinases mediate betel quid-induced oral cancer cell motility and could be a biomarker for early invasion in oral squamous cell carcinoma.

PubMed:Experimental studies on betel nut and tobacco carcinogenicity.

PubMed:Influence of alpha-tocopherol and ascorbic acid on pan masala induced genomic damage. An in vitro experiment.

PubMed:Genotoxic and non-genotoxic effects of betel quid ingredients on oral mucosal fibroblasts in vitro.

PubMed:O6-methylguanine-DNA methyltransferase activity in human buccal mucosal tissue and cell cultures. Complex mixtures related to habitual use of tobacco and betel quid inhibit the activity in vitro.

PubMed:Studies on promoting activity of Taiwan betel quid ingredients in hamster buccal pouch carcinogenesis.

PubMed:Inhibitory action of Piper betle on the initiation of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in rats.

PubMed:Ethanol potentiates the clastogenicity of pan masala--an in vitro experience.

PubMed:Evaluation of carcinogenic/co-carcinogenic activity of a common chewing product, pan masala, in mouse skin, stomach and esophagus.

PubMed:Stabilisation of collagen by betel nut polyphenols as a mechanism in oral submucous fibrosis.

PubMed:The influence of pH on the convertogenic activity of plant phenolics.

PubMed:Nonmutagenicity of betel leaf and its antimutagenic action against environmental mutagens.

PubMed:Evaluation of chemopreventive effects of betel leaf on the genotoxicity of pan masala.

PubMed:Morphological transformation, sister chromatid exchange and mutagenesis assay of betel constituents.

PubMed:Protective single/combined treatment with betel leaf and turmeric against methyl (acetoxymethyl) nitrosamine-induced hamster oral carcinogenesis.

PubMed:An in vitro assessment of the genotoxic potential of pan masalas.

PubMed:Effect of Piper betle L. and its extracts on the growth and aflatoxin production by Aspergillus parasiticus.

PubMed:The presence of cholinomimetic and calcium channel antagonist constituents in Piper betle Linn.

PubMed:Modifying influences of betel quid ingredients on B(a)P-induced carcinogenesis in the buccal pouch of hamster.

PubMed:Chemoprevention of mammary tumor virus-induced and chemical carcinogen-induced rodent mammary tumors by natural plant products.

PubMed:Response of fibroblast cultures from ataxia-telangiectasia patients to oxidative stress.

PubMed:Role of mouse spleen cell HMG proteins and their poly-ADP-ribosylation in betelnut induced carcinogenesis.

PubMed:Acute toxicities of betel nut: rare but probably overlooked events.

PubMed:Cancer-promoting effect of Taiwan betel quid in hamster buccal pouch carcinogenesis.

PubMed:Mutual interactions among ingredients of betel quid in inducing genotoxicity on Chinese hamster ovary cells.

PubMed:Pan masala--a genotoxic menace.

PubMed:Embryotoxicity of betel nuts in mice.

PubMed:Upregulation of matrix metalloproteinase-1 (MMP-1) expression in oral carcinomas of betel quid (BQ) users: roles of BQ ingredients in the acceleration of tumour cell motility through MMP-1.

PubMed:Effect of glutathione on arecanut treated normal human buccal fibroblast culture.

PubMed:The tumor promoting effect of lime-piper betel quid in JB6 cells.

PubMed:Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan.

PubMed:Evaluation of the mutagenicity of 'pan masala', a chewing substitute widely used in India.

PubMed:Correlation of mutagenicity and tumorigenicity of betel quid and its ingredients.

PubMed:Inhibition of DNA synthesis in cultured lymphocytes and tumor cells by extracts of betel nut, tobacco, and miang leaf, plant substances associated with cancer of the ororespiratory epithelium.

PubMed:Chromosome-damaging effect of betel leaf.

PubMed:Role of lime in the generation of reactive oxygen species from betel-quid ingredients.

PubMed:Active-oxygen scavenging activity of traditional nourishing-tonic herbal medicines and active constituents of Rhodiola sacra.

PubMed:Relationship between cellular levels of beta-carotene and sensitivity to genotoxic agents.

PubMed:Allergenic relationship among four common and dominant airborne palm pollen grains from Eastern India.

PubMed:Anthiovulatory activity of five indigenous plants in rabbits.

PubMed:Effects of aqueous extracts of "Betel quid" and its constituents on testosterone production by dispersed mouse interstitial cells.

PubMed:Hypoglycemic effects of Potentilla fulgens L in normal and alloxan-induced diabetic mice.

PubMed:Inhibitory effect of bupleuri radix saponins on adhesion of some solid tumor cells and relation to hemolytic action: screening of 232 herbal drugs for anti-cell adhesion.

PubMed:Carotenoids suppress proliferating cell nuclear antigen and cyclin D1 expression in oral carcinogenic models.

PubMed:Human vaginal mucosa as a model of buccal mucosa for in vitro permeability studies: an overview.

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