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ginkgo biloba leaf extract
extract of the leaves of ginkgo biloba, ginkgoaceae

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Name:ginkgo biloba leaf extract
CAS Number: 90045-36-6
ECHA EC Number:289-896-4
FDA UNII: Search
Category:cosmetic agents, dietary supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 36 Chromium picolinate; Ginkgo biloba leaf extract; and Ginseng extract View - notice PDF
 
Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
 
Suppliers:
Augustus Oils
Augaherb Ginkgo Biloba Leaf Extract Botanical Extract
Services
AuNutra® Industries
Ginkgolden™ Ginkgo Biloba Extract
Bell Flavors & Fragrances
Gingko Biloba Extract Natural
Bio-Botanica®
Ginkgo Biloba, AF – 5474
Bio-Botanica®
Ginkgo Leaf Ginkgo Biloba Leaf Extract
Bristol Botanicals
Ginkgo leaf fluid extract Ginkgo biloba 1:1 25%
Carrubba
ginkgo biloba extract
Changsha Organic Herb
Ginkgo Biloba Extract(Maidenhair tree Extract)
Charkit Chemical
GINKGO BILOBA EXTRCT PDWR 24/6
Dongguan Meiherb Biotech
Ginkgo Biloba Extract
Odor: characteristic
Use: Ginkgo Biloba extract is widely used in medicine, health products, food & beverage additives, cosmetics and other fields.
Global Essence
Gingko Extract
Grau Aromatics
GINKGO EXTRACT HS 2464 G
(hydrosoluble)
Grau Aromatics
GINKGO EXTRACT LS 4131 G
(liposoluble)
H. Erhard Wagner
PhytoVital Ginkgo
Haldin International
Ginkgo Biloba
Indenta Group
Gingko Biloba
Jiangyin Healthway
Ginkgo Biloba P.E.
New functional food ingredients
Naturex
Ginkgo Biloba Extract
NAT healthy™
Shaanxi Y-Herb Biotechnology
Dried Ginkgo Biloba Leaf Extract Powder Water Soluble Flavones 24% Lactones 6%
SRS Aromatics
GINKGO EXTRACT HS 2464 G
SRS Aromatics
GINKGO EXTRACT LS 4131 G
Symrise
Extrapone® Ginkgo Biloba
Life Essentials - Botanicals
Odor: characteristic
Use: Extrapone® Ginkgo Biloba contains the extract of Ginkgo biloba L. leaves prepared in water and propylene glycol. Ginkgo used for Extrapone® Ginkgo Biloba is mainly cultivated in China. The ginkgo leaves are dried, if necessary comminuted, extracted with water and filtrated. The filtrate is concentrated by distillation. The concentrated extract is prepared in a mixture of water, propylene glycol and preservatives and is clear filtrated after an individual ripening time. 1 kg Extrapone® Ginkgo Biloba contains the hydrophilic ingredients of approx. 300 g dried, resp. approx. 2300 g fresh ginkgo leaves. Dried plant material � Extrapone® Ginkgo � ratio: 0.30 : 1. Fresh plant material � Extrapone® Ginkgo - ratio: 2.30 : 1
Tianjin Talent Chemical
Ginkgo Biloba Extract
Vege Tech
ginkgo leaf extract
Vege Tech
Organic Ginkgo (Fresh) Extract
Xi'an Greena Biotech
Ginkgo Biloba Extract
Odor: characteristic
Use: Ginkgo biloba, which is also known as maidenhair, has been traced back nearly 300 million years making it the oldest surviving tree species on earth.Ginkgo biloba Extract is a natural extract derived from the leaf of the Chinese ginkgo tree.It is native parts of Asia, including China, Japan, and Korea. Ginkgo biloba has been used in China medicinally to heal various health ailments for thousands of years.According to current research, ginkgo biloba benefits include improved cognitive function, positive mood, increased energy, improved memory and reduced symptoms related to multiple chronic diseases and so on.
Xian Yuensun Biological Technology
Ginkgo Biloba Extract
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-mouse LD50 162 mg/kg

oral-man TDLo 8 mg/kg/1W-I
SENSE ORGANS AND SPECIAL SENSES: HEMORRHAGE: EYE SENSE ORGANS AND SPECIAL SENSES: CORNEAL DAMAGE: EYE
New England Journal of Medicine. Vol. 336, Pg. 1108, 1997.

intravenous-mouse LD50 162000 mg/kg
Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 20, Pg. 22, 1989.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic agents, dietary supplements
Recommendation for ginkgo biloba leaf extract usage levels up to:
 not for fragrance use.
 
Recommendation for ginkgo biloba leaf extract flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Safety and efficacy of a feed additive consisting of a dried extract from the leaves of Ginkgo biloba L. (G. biloba dry extract) for use in cats and dogs (C.I.A.M.)
View page or View pdf

ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
ginkgo biloba leaf extract
Chemidplus:0090045366
 
References:
 ginkgo biloba leaf extract
Pubchem (sid):135282640
 
Other Information:
Export Tariff Code:1302.19.0000
FDA Listing of Food Additive Status:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 skin conditioning
 
Occurrence (nature, food, other):note
 ginkgo biloba
Search Trop Picture
 
Synonyms:
 augaherb ginkgo biloba leaf AG
 augaherb ginkgo biloba leaf AG (Augustus)
 extract of the leaves of ginkgo biloba, ginkgoaceae
 gingko biloba extract natural
extrapone ginkgo biloba (Symrise)
ginkgolden ginkgo biloba extract
 ginkgo biloba extract(maidenhair tree extract)
 ginkgo biloba extract, 24%/6% ginkgoflavoglycosides terpene lactones
 ginkgo biloba extract, 24%/6% ginkgoflavoglycosides terpene lactones, < 5 ppm ginkgolic acid
 ginkgo extract HS 2464 G (Grau)
 ginkgo extract LS 4131 G (Grau)
 ginkgo leaf extract
 

Articles:

PubMed:Development of a dynamic multiple reaction monitoring method for determination of digoxin and six active components of Ginkgo biloba leaf extract in rat plasma.
J-Stage:Comprehensive Analysis of Flavonols in Ginkgo biloba Products by Ultra-High-Performance Liquid Chromatography Coupled with Ultra-Violet Detection and Time-of-Flight Mass Spectrometry
J-Stage:Investigation of Biologically Active Components in Ginkgo Leaf Products on the Japanese Market
PubMed:HILIC-UPLC-MS/MS combined with hierarchical clustering analysis to rapidly analyze and evaluate nucleobases and nucleosides in Ginkgo biloba leaves.
PubMed:Mechanistic evaluation of Ginkgo biloba leaf extract-induced genotoxicity in L5178Y cells.
PubMed:Adulteration of Ginkgo biloba products and a simple method to improve its detection.
PubMed:Phytochemical and medicinal importance of Ginkgo biloba L.
PubMed:Hepatoprotective effect of Ginkgo biloba leaf extract on lantadenes-induced hepatotoxicity in guinea pigs.
PubMed:Quantification of a botanical negative marker without an identical standard: ginkgotoxin in Ginkgo biloba.
PubMed:Direct determination of underivatized amino acids from Ginkgo biloba leaves by using hydrophilic interaction ultra high performance liquid chromatography coupled with triple quadrupole mass spectrometry.
PubMed:A novel substance with allelopathic activity in Ginkgo biloba.
PubMed:Action Mechanism of Ginkgo biloba Leaf Extract Intervened by Exercise Therapy in Treatment of Benign Prostate Hyperplasia.
PubMed:Ginkgo biloba leaf extract improves the cognitive abilities of rats with D-galactose induced dementia.
PubMed:Hepatocellular carcinomas in B6C3F1 mice treated with Ginkgo biloba extract for two years differ from spontaneous liver tumors in cancer gene mutations and genomic pathways.
PubMed:Anti-influenza virus activity of Ginkgo biloba leaf extracts.
PubMed:Ginkgo biloba leaf extract (EGb 761®) and its specific acylated flavonol constituents increase dopamine and acetylcholine levels in the rat medial prefrontal cortex: possible implications for the cognitive enhancing properties of EGb 761®.
PubMed:Design of countercurrent separation of Ginkgo biloba terpene lactones by nuclear magnetic resonance.
PubMed:[Ginkgo biloba--effect, adverse events and drug interaction].
PubMed:[Effect of Gingkgo biloba leaf extract induced delayed preconditioning on cytochrome c oxidase expression during myocardial ischemia-reperfusion in rats].
PubMed:Protective effect of Ginkgo biloba L. leaf extract against glyphosate toxicity in Swiss albino mice.
PubMed:Stimulation of DNA repair in Saccharomyces cerevisiae by Ginkgo biloba leaf extract.
PubMed:Proanthocyanidins from Ginkgo biloba leaf extract and their radical scavenging activity.
PubMed:Ginkgo biloba extract (EGb 761) normalizes hypertension in 2K, 1C hypertensive rats: role of antioxidant mechanisms, ACE inhibiting activity and improvement of endothelial dysfunction.
PubMed:The effect of Ginkgo biloba extract on mitochondrial oxidative phosphorylation in the normal and ischemic rat heart.
PubMed:Polyphenols from Ginkgo biloba.
PubMed:Fingerprint development for Ginkgo biloba extracts by pressurized capillary electrochromatography: comparison of column types.
PubMed:Effects of Ginkgo biloba extract on promotion of neurogenesis in the hippocampal dentate gyrus in C57BL/6 mice.
PubMed:Summative interaction between astaxanthin, Ginkgo biloba extract (EGb761) and vitamin C in suppression of respiratory inflammation: a comparison with ibuprofen.
PubMed:Ginkgo biloba extract (EGb761) protects against aging-related caspase-mediated apoptosis in rat cochlea.
PubMed:[Effect of GBE50 on experimental arrhythmias].
PubMed:Ginkgo biloba leaf extract action in scavenging free radicals and reducing mutagenicity and toxicity of cigarette smoke in vivo.
PubMed:Analysis of terpene lactones in a Ginkgo leaf extract by high-performance liquid chromatography using charged aerosol detection.
PubMed:Ginkgo biloba extract induces gene expression changes in xenobiotics metabolism and the Myc-centered network.
PubMed:Protective role of Ginkgo biloba against hepatotoxicity and nephrotoxicity in uranium-treated mice.
PubMed:Safety and effectiveness of a traditional ginkgo fresh plant extract - results from a clinical trial.
PubMed:Optimization of extraction technique and validation of developed RP-HPLC-ELSD method for determination of terpene trilactones in Ginkgo biloba leaves.
PubMed:Gingko biloba leaf extract induces oxidative stress in carcinoma HSC-2 cells.
PubMed:Organized intrasylvian subarachnoid hematoma in post-traumatic child with dyskinesia for 8 years: a case report and review of the literature.
PubMed:Effect of Ginkgo leaf extract on vascular endothelial function in patients with early stage diabetic nephropathy.
PubMed:Transcriptome profiling analysis reveals multiple modulatory effects of Ginkgo biloba extract in the liver of rats on a high-fat diet.
PubMed:Neuromodulatory property of standardized extract Ginkgo biloba L. (EGb 761) on memory: behavioral and molecular evidence.
PubMed:Dual effects of Ginkgo biloba leaf extract on human red blood cells.
PubMed:Biology and chemistry of Ginkgo biloba.
PubMed:Chronic administration of a Ginkgo biloba leaf extract facilitates acquisition but not performance of a working memory task.
PubMed:Intra-amygdaloid infusion of Ginkgo biloba leaf extract (EGb761) facilitates fear-potentiated startle in rats.
PubMed:Multifaceted therapeutic benefits of Ginkgo biloba L.: chemistry, efficacy, safety, and uses.
PubMed:[Purification and identification of genistein in Ginkgo biloba leaf extract].
PubMed:Suppression of oxidized LDL-induced PDGF receptor beta activation by ginkgo biloba extract reduces MMP-1 production in coronary smooth muscle cells.
PubMed:[Therapeutic effect of Ginkgo biloba leaf extract on hypercholestrolemia in children with nephrotic syndrome].
PubMed:[The digital criterion of the potential information characteristics of the traditional Chinese medicine chromatographic fingerprints].
PubMed:Ginkgo biloba leaf extract (EGb761) combined with neuroprotective agents reduces the infarct volumes of gerbil ischemic brain.
PubMed:[Brain protective effects of ginkgo biloba leaf extract (ginaton) in patients undergoing hypothermic cardiopulmonary bypass].
PubMed:Involvement of Ca2+, CaMK II and PKA in EGb 761-induced insulin secretion in INS-1 cells.
PubMed:Ginkgo biloba leaf extract reverses amyloid beta-peptide-induced isoprostane production in rat brain in vitro.
PubMed:Ginkgo biloba leaf extract (EGb 761) diminishes adriamycin-induced hyperlipidaemic nephrotoxicity in rats: association with nitric oxide production.
PubMed:Reduction of behavioural disturbances in elderly dogs supplemented with a standardised Ginkgo leaf extract.
PubMed:[Effects of Ginaton on the markers of myocardial injury during cardiopulmonary bypass].
PubMed:Protective effect of Ginkgo biloba leaf extract on learning and memory deficit induced by aluminum in model rats.
PubMed:A concise synthesis of ginkgolide M, a minor component of a terpene trilactone fraction from ginkgo biloba roots.
PubMed:Alzheimer's disease, the nematode Caenorhabditis elegans, and ginkgo biloba leaf extract.
PubMed:Effects of herbal extracts on the function of human organic anion-transporting polypeptide OATP-B.
PubMed:Ginkgo biloba leaf extract (EGb 761) enhances catalepsy induced by haloperidol and L-nitroarginine in mice.
PubMed:Protective effects of Ginkgo biloba leaf extract on aluminum-induced brain dysfunction in rats.
PubMed:Inhibition of platelet activating factor (PAF)-induced aggregation of human thrombocytes by ginkgolides: considerations on possible bleeding complications after oral intake of Ginkgo biloba extracts.
PubMed:Studies on interactions between functional foods or dietary supplements and medicines. III. Effects of ginkgo biloba leaf extract on the pharmacokinetics of nifedipine in rats.
PubMed:Studies on interactions between functional foods or dietary supplements and medicines. IV. Effects of ginkgo biloba leaf extract on the pharmacokinetics and pharmacodynamics of nifedipine in healthy volunteers.
PubMed:[Effect of combination of Ginkgo leaf extract and deferoxamine in preventing and treating ototoxicity of cisplatin].
PubMed:[Clinical observation on treatment of diabetic peripheral neuphropathy by ginkgo leaf extract combined with active vitamin B12].
PubMed:Sample preparation and determination of ginkgo terpene trilactones in selected beverage, snack, and dietary supplement products by liquid chromatography with evaporative light-scattering detection.
PubMed:Ginkgolides, diterpene trilactones of Ginkgo biloba, as antagonists at recombinant alpha1beta2gamma2L GABAA receptors.
PubMed:The leaf extract of Ginkgo Biloba L. suppresses oxidized LDL-stimulated fibronectin production through an antioxidant action in rat mesangial cells.
PubMed:Effect of one week treatment with Ginkgo biloba extract (EGb761) on ischemia-induced infarct volume in gerbils.
PubMed:Structure-activity studies with Ginkgo biloba extract constituents as receptor-gated chloride channel blockers and modulators.
PubMed:Studies on interactions between functional foods or dietary supplements and medicines. I. Effects of Ginkgo biloba leaf extract on the pharmacokinetics of diltiazem in rats.
PubMed:Prenatal exposure of rats to Ginkgo biloba extract (EGb 761) increases neuronal survival/growth and alters gene expression in the developing fetal hippocampus.
PubMed:[The cellular mechanism of angiotensin II inhibition on BKCa of ECV304 cell and the protective effect of gingko leaf extract].
PubMed:Bilobalide, a sesquiterpene trilactone from Ginkgo biloba, is an antagonist at recombinant alpha1beta2gamma2L GABA(A) receptors.
PubMed:Effect of Ginkgo biloba leaf extract on electroencephalography of rat with cerebral ischemia and reperfusion.
PubMed:Ginkgo biloba leaf extract enhances levels of caspase-3 and amyloid precursor protein in normal rat hippocampus.
PubMed:Anti-apoptotic properties of Ginkgo biloba extract EGb 761 in differentiated PC12 cells.
PubMed:Ginkgo biloba leaf extract: review of biological actions and clinical applications.
PubMed:A case of cerebral haemorrhage-can Ginkgo biloba be implicated?
PubMed:Determination of trace amounts of ginkgolic acids in Ginkgo biloba L. leaf extracts and phytopharmaceuticals by liquid chromatography-electrospray mass spectrometry.
PubMed:Identification of kaempferol as a monoamine oxidase inhibitor and potential Neuroprotectant in extracts of Ginkgo biloba leaves.
PubMed:Inhibitory effect of the leaf extract of Ginkgo biloba L. on oxidative stress-induced platelet aggregation.
PubMed:The sensitizing capacity of ginkgolic acids in guinea pigs.
PubMed:The bioavailability of ginkgolides in Ginkgo biloba extracts.
PubMed:Enhancement of radiation effect by Ginkgo biloba extract in C3H mouse fibrosarcoma.
 
Notes:
the only specie of the genus ginkgo, family ginkgoacea. it is the source of extracts of medicinal interest, especially egb 761. ginkgo may refer to the genus or species
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