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Category:antioxidants
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | antioxidants |
| Recommendation for vitex rotundifolia leaf oil usage levels up to: | | | not for fragrance use.
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| Recommendation for vitex rotundifolia leaf oil flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| roundleaf | chaste tree leaf oil | | roundleaf | chastetree leaf oil | | | vitex ovata leaf oil | | | vitex ovata var. subtrisecta leaf oil | | | vitex trifolia var. ovata leaf oil | | | vitex trifolia var. simplicifolia leaf oil | | | vitex trifolia var. unifoliolata leaf oil | | | volatile oil obtained from the leaves of vitex rotundifolia |
Articles:
| PubMed:Determination and Identification of a Specific Marker Compound for Discriminating Shrub Chaste Tree Fruit from Agnus Castus Fruit Based on LC/MS Metabolic Analysis. |
| PubMed:Identification of New Diterpenes as Putative Marker Compounds Distinguishing Agnus Castus Fruit (Chaste Tree) from Shrub Chaste Tree Fruit (Viticis Fructus). |
| PubMed:Casticin, an active compound isolated from Vitex Fructus, ameliorates the cigarette smoke-induced acute lung inflammatory response in a murine model. |
| PubMed:5,3'-Dihydroxy-6,7,4'-trimethoxyflavanone exerts its anticancer and antiangiogenesis effects through regulation of the Akt/mTOR signaling pathway in human lung cancer cells. |
| PubMed:Casticin inhibits COX-2 and iNOS expression via suppression of NF-κB and MAPK signaling in lipopolysaccharide-stimulated mouse macrophages. |
| PubMed:Activation of the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway is involved in the casticin-induced apoptosis of colon cancer cells. |
| PubMed:Development of microsatellite markers for Vitex rotundifolia (Verbenaceae), an endangered coastal plant in Lake Biwa, Japan. |
| PubMed:Antiproliferative effect of flavonoids from the halophyte Vitex rotundifolia on human cancer cells. |
| PubMed:A synthetic compound, 4-acetyl-3-methyl-6-(3,4,5-trimethoxyphenyl)pyrano[3,4-c]pyran-1,8-dione, ameliorates ovalbumin-induced asthma. |
| PubMed:Anti-inflammatory constituents from the fruits of Vitex rotundifolia. |
| PubMed:Vitexicarpin acts as a novel angiogenesis inhibitor and its target network. |
| PubMed:A novel synthetic compound 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c]pyran-1,8-dione inhibits the production of nitric oxide and proinflammatory cytokines via the NF-κB pathway in lipopolysaccharide-activated microglia cells. |
| PubMed:Vitex rotundifolia L. prevented airway eosinophilic inflammation and airway remodeling in an ovalbumin-induced asthma mouse model. |
| PubMed:Vitexicarpin induces apoptosis in human prostate carcinoma PC-3 cells through G2/M phase arrest. |
| PubMed:Vascular protective role of vitexicarpin isolated from Vitex rotundifolia in human umbilical vein endothelial cells. |
| PubMed:Inhibitory effects of casticin on migration of eosinophil and expression of chemokines and adhesion molecules in A549 lung epithelial cells via NF-κB inactivation. |
| PubMed:Casticin, a flavonoid isolated from Vitex rotundifolia, inhibits prolactin release in vivo and in vitro. |
| PubMed:A new compound, 1H,8H-pyrano[3,4-c]pyran-1,8-dione, suppresses airway epithelial cell inflammatory responses in a murine model of asthma. |
| PubMed:Inhibition effects of Vitex rotundifolia on inflammatory gene expression in A549 human epithelial cells. |
| PubMed:Casticin induces leukemic cell death through apoptosis and mitotic catastrophe. |
| PubMed:Beach dune sand hydrophobicity due to the presence of beach vitex ( Vitex rotundifolia L. f.). |
| PubMed:Population genetic structure of the medicinal plant Vitex rotundifolia in China: implications for its use and conservation. |
| PubMed:Estrogen-like activity of volatile components from Vitex rotundifolia L. |
| PubMed:Evaluation of the estrogenic activity of the constituents in the fruits of Vitex rotundifolia L. for the potential treatment of premenstrual syndrome. |
| PubMed:Association between chemical and genetic variation of Vitex rotundifolia populations from different locations in China: its implication for quality control of medicinal plants. |
| PubMed:Identification of methyl chloride-emitting plants and atmospheric measurements on a subtropical island. |
| PubMed:Anti-nociceptive and anti-hyperprolactinemia activities of Fructus Viticis and its effective fractions and chemical constituents. |
| PubMed:Phenolic compounds and flavonoids as plant growth regulators from fruit and leaf of Vitex rotundifolia. |
| PubMed:G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.). |
| PubMed:Effects of luteolin on the inhibition of proliferation and induction of apoptosis in human myeloid leukaemia cells. |
| PubMed:New diterpenes and norditerpenes from the fruits of Vitex rotundifolia. |
| PubMed:Rotundifuran, a labdane type diterpene from Vitex rotundifolia, induces apoptosis in human myeloid leukaemia cells. |
| PubMed:Phenylnaphthalene compounds from the subterranean part of Vitex rotundifolia and their antibacterial activity against methicillin-resistant Staphylococcus aureus. |
| PubMed:Ten new labdane-type diterpenes from the fruit of Vitex rotundifolia. |
| PubMed:Polymethoxyflavonoids from Vitex rotundifolia inhibit proliferation by inducing apoptosis in human myeloid leukemia cells. |
| PubMed:Effect of Vitex rotundifolia on immediate-type allergic reaction. |
| PubMed:Diterpenes from the fruits of Vitex rotundifolia. |
| PubMed:Vitexicarpin, a flavonoid from the fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines in vitro. |
| PubMed:Pharmacologically active components of viticis fructus (Vitex rotundifolia). II. The components having analgesic effects. |
| PubMed:Rotundial, a new natural mosquito repellent from the leaves of Vitex rotundifolia. |
| PubMed:Isolation of an aldose reductase inhibitor from the fruits of Vitex rotundifolia Part 2 in the series "Studies on the inhibitory effects of medicinal plant constituents on cataract formation". |
| PubMed:Studies on the constituents of Vitex rotundifolia L. fil. |
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