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Category:fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | alcohol | | | water, 301.1 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 17, Pg. 817, 1979.
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| Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 17, Pg. 817, 1979.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | essential oil obtained from the leaves of the thujopsis dolabrata, cupressaceae | | | hiba leaf oil |
Articles:
| PubMed:Reduction of the chronic stress response by inhalation of hiba (Thujopsis dolabrata) essential oil in rats. |
| PubMed:Toxicity of hiba oil constituents and spray formulations to American house dust mites and copra mites. |
| PubMed:Mast cell stabilizing effect of (-)-Elema-1,3,11(13)-trien-12-ol and thujopsene from Thujopsis dolabrata is mediated by down-regulation of interleukin-4 secretion in antigen-induced RBL-2H3 cells. |
| PubMed:In vitro and in vivo anti-plasmodial activity of essential oils, including hinokitiol. |
| PubMed:Isolation and characterization of microsatellite markers for Thujopsis dolabrata var. hondai (Cupressaceae). |
| PubMed:Antifungal properties of Japanese cedar essential oil from waste wood chips made from used sake barrels. |
| PubMed:Effects of a combination of hinokitiol (β-thujaplicin) and an organic acid mixture on ruminal fermentation in heifers fed a high-grain diet. |
| PubMed:In vitro Na+/K+-ATPase inhibitory activity and antimicrobial activity of sesquiterpenes isolated from Thujopsis dolabrata. |
| PubMed:Isolation of (-)-4'-demethyl traxillagenin from Thujopsis dolabrata Sieb. et Zucc. var. hondai Makino. |
| PubMed:The antifungal compound totarol of Thujopsis dolabrata var. hondai seeds selects for fungi on seedling root surfaces. |
| PubMed:The mechanism of the bactericidal activity of hinokitiol. |
| PubMed:The excellence of Aomori Hiba (Hinokiasunaro) in its use as building materials of Buddhist temples and Shinto shrines. |
| PubMed:Biological activity of beta-dolabrin, gamma-thujaplicin, and 4-acetyltropolone, hinokitiol-related compounds. |
| PubMed:Biological activity of alpha-thujaplicin, the isomer of hinokitiol. |
| PubMed:Biological activity of tropolone. |
| PubMed:Characterization of (-)-matairesinol as a potent inhibitor of casein kinase I in vitro. |
| PubMed:Differential effects of the hiba odor on CNV and MMN. |
| PubMed:Biological activity of 4-acetyltropolone, the minor component of Thujopsis dolabrata SIeb. et Zucc. hondai Mak. |
| PubMed:Chemotaxonomy on the leaf constituents of Thujopsis dolabrata Sieb. et Zucc.-Analysis of neutral extracts (diterpene hydrocarbon). |
| PubMed:Biological activity of alpha-thujaplicin, the minor component of Thujopsis dolabrata SIEB. et ZUCC. var. hondai MAKINO. |
| PubMed:Cytotoxicity of the hinokitiol-related compounds, gamma-thujaplicin and beta-dolabrin. |
| PubMed:Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities. |
| PubMed:Phytogrowth-Inhibitory activities of beta-dolabrin and gamma-thujaplicin, hinokitiol-related compounds and constituents of Thujopsis dolabrata Sieb. et Zucc. var hondai Makino. |
| PubMed:Antimicrobial activity and metalloprotease inhibition of hinokitiol-related compounds, the constituents of Thujopsis dolabrata S. and Z. hondai MAK. |
| PubMed:Survival strategy of hiba (Thujopsis dolabrata var. hondae) and two broad-leaved trees in northern Japan in response to creep and glide pressures of snow. |
| PubMed:Induction of hepatic P450s in rat by essential wood and leaf oils. |
| PubMed:Liver-protective principle of Thujopsis dolabrata leaves. |
| PubMed:Cytotoxic agents of Thujopsis dolabrata (L. fil.) Sieb. et Zucc. |
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Among numerous varieties of thuja all over the world is the Japanese Thuja Dolobrata. This tree grows also in certain parts of Asia and in the southern parts of the U.S.S.R. In Japan, the leaves and the wood are used for the distillation of the oil.
tsca definition 2008: extractives and their physically modified derivatives. thujopsis dolabrata, cupressaceae.
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