litsea cubeba oil terpeneless 5392-40-5

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    Citrus and Allied Essences
    
    Oil Litsea Cubeba Terpeneless 95%
    
    Market Report
    
    Citrus and Allied Essences
    
    Oil Litsea Cubeba Terpeneless Extra

Organoleptic Properties

Odor Type :	citrus
Odor Strength :	medium
Odor Description: at 100.00 %.	sweet lemon citral Luebke, William tgsc, (1997)
Odor sample from :	CA Aromatics Company Inc.
Taste Description:	lemon
Substantivity :	24 Hour(s)

Properties

Physical Properties

Appearance :	pale yellow clear liquid (est)
Food Chemicals Codex Listed :	No
Specific Gravity :	0.88500 to 0.89100 @ 25.00 °C.
Pounds per Gallon - (est). :	7.364 to 7.414
Refractive Index :	1.48600 to 1.49000 @ 20.00 °C.
Boiling Point :	227.00 °C. @ 760.00 mm Hg
Vapor Pressure :	0.091000 mm/Hg @ 25.00 °C.
Flash Point :	195.00 °F. TCC ( 90.56 °C. )
logP (o/w) :	3.127 (est)

Safety

Safety Information

Most important hazard(s) :	Xi - Irritant
	R 36/38 - Irritating to skin and eyes. R 43 - May cause sensitisation by skin contact. S 24 - Avoid contact with skin. S 25 - Avoid contact with eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37 - Wear suitable gloves.
Oral/Parenteral Toxicity :
	intraperitoneal-rat LD50 460 mg/kg Journal of Reproduction and Fertility. Vol. 55, Pg. 347, 1979. oral-mouse LD50 6000 mg/kg Biochemical Journal. Vol. 34, Pg. 1196, 1940. oral-rat LD50 4960 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.
Dermal Toxicity :
	skin-rabbit LD50 2250 mg/kg Food and Chemical Toxicology. Vol. 25, Pg. 505, 1987.
Inhalation Toxicity :
	Not determined

Safety in Use

Safety in Use Information

Category :	flavor and fragrance agents
IFRA Critical Effect :	Sensitization
contains the following IFRA (Annex) restricted components : (non-analysis max. level reference only)
citral		Max. Found: <96.00 % and Reason: Sensitization
IFRA :	View Standard
Fragrance usage is IFRA RESTRICTED. View Standard for complete information.
Please review all IFRA documents for complete information.
IFRA categories : limits in the finished product: (For a description of the categories, refer to the IFRA QRA Information Booklet.)
Category 1 :	0.04 % (1)	Category 2 :	0.05 %
Category 3 :	0.20 %	Category 4 :	0.60 %
Category 5 :	0.30 %	Category 6 :	1.00 % (1)
Category 7 :	0.10 %	Category 8 :	1.40 %
Category 9 :	5.00 %	Category 10 :	2.50 %
Category 11 :	See Note (2)
	Notes :
	(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofi.org).
	(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.
Recommendation for litsea cubeba oil terpeneless flavor usage levels up to :
	170.0000 ppm in the finished product.

Safety References

EPI System :	View
Chemicalize.org :	Calculate predicted properties
NLM Hazardous Substances Data Bank :	Search
Chemical Carcinogenesis Research Information System :	Search
Cancer Citations :	Search
Toxicology Citations :	Search
Env. Mutagen Info. Center :	Search
NLM Developmental and Reproductive Toxicity :	Search
National Toxicology Program :	Search
EPA Substance Registry Services (TSCA) :	5392-40-5
EPA ACToR :	Toxicology Data
National Institute of Allergy and Infectious Diseases :	Data
SCCNFP :	opinion
WGK Germany :	1
	3,7-dimethylocta-2,6-dienal
DTP/NCI :	6170
Chemidplus :	0005392405
EPA/NOAA CAMEO :	hazardous materials
RTECS :	RG5075000 for cas# 5392-40-5

Articles

Articles for the Flavor and Fragrance Industries

PubMed :	Modeling with the logistic regression of the growth/no growth interface of Saccharomyces cerevisiae in relation to 2 antimicrobial terpenes (citral and linalool), pH, and aw.
PubMed :	Flavor of cold-hardy grapes: impact of berry maturity and environmental conditions.
PubMed :	Effect of ubiquinol-10 on citral stability and off-flavor formation in oil-in-water (O/W) nanoemulsions.
PubMed :	Identification of gustatory-olfactory flavor mixtures: effects of linguistic labeling.
PubMed :	Stability of citral in emulsions coated with cationic biopolymer layers.
PubMed :	Intake of dried bonito broth flavored with dextrin solution induced conditioned place preference in mice.
PubMed :	Flavor-intensity perception: effects of stimulus context.
PubMed :	Enhancement of retronasal odors by taste.
PubMed :	Inhibition of citral degradation by oil-in-water nanoemulsions combined with antioxidants.
PubMed :	Flavored waters: influence of ingredients on antioxidant capacity and terpenoid profile by HS-SPME/GC-MS.
PubMed :	Influence of droplet charge on the chemical stability of citral in oil-in-water emulsions.
PubMed :	Coactivation of gustatory and olfactory signals in flavor perception.
PubMed :	Stability of citral in oil-in-water emulsions prepared with medium-chain triacylglycerols and triacetin.
PubMed :	Encapsulation performance of proteins and traditional materials for spray dried flavors.
PubMed :	Flavor authentication studies of alpha-ionone, beta-ionone, and alpha-ionol from various sources.
PubMed :	Chemical and physical stability of citral and limonene in sodium dodecyl sulfate-chitosan and gum arabic-stabilized oil-in-water emulsions.
PubMed :	Flavor components of monoterpenes in citrus essential oils enhance the release of monoamines from rat brain slices.
PubMed :	Tyrosinase inhibitory activity of citrus essential oils.
PubMed :	Essential oil composition of diploid and tetraploid clones of ginger (Zingiber officinale Roscoe) grown in Australia.
PubMed :	Acute and genetic toxicity of essential oil extracted from Litsea cubeba (Lour.) Pers.
PubMed :	Validation of a stimulation protocol suited to the investigation of odor-taste interactions with fMRI.
PubMed :	Aerosolized essential oils and individual natural product compounds as brown treesnake repellents.
PubMed :	Thresholds of carcinogenicity of flavors.
PubMed :	A review of the interactions between milk proteins and dairy flavor compounds.
PubMed :	Comparative study of experimentally induced benign and atypical hyperplasia in the ventral prostate of different rat strains.
PubMed :	Food deprivation reduces rats' oil preference.
PubMed :	Benzaldehyde, citral, and d-limonene flavor perception in the presence of casein and whey proteins.